Eun Hyun Ahn is an instructor in the Department of Biomedical Engineering. Ahn’s research lab has focuses on the detection of low-frequency mutations on a genome-wide level using a novel deep sequencing technology termed Duplex Sequencing (DS) and the regulation of cell function by microenvironments such as extracellular matrix (ECM)-biomimetic nanotopography. These cutting-edge experimental approaches have been applied to study genomic changes and migratory phenotypes of breast cancer and glioblastoma. The ultimate goals of the Ahn lab’s current and future research projects are to identify biomarkers for the early detection of therapy resistance and tumor recurrence using cutting-edge deep sequencing and ECM-biomimetics technologies, and to develop a novel strategy for preclinical screening of anti-migratory chemotherapeutic agents.
