Analysis of Ethics Surrounding Automated Vehicles

Prof. Igusa & Prof. Johnathon Ehsani (Bloomberg School of Public Health) hope that their work regarding ethics of autonomous vehicle testing can help shape recommendations for regulatory bodies and state and industry lawmakers.

Radiation Therapy for Brain Tumors

Prof. Kimia Ghobadi is working to analyze how to target high does of radiation to brain tumors while sparing as much healthy tissue as possible.

Climate Change, Superstorms, and Civil Engineering

Prof. Sauleh Siddiqui speaks on how the field of civil engineering is changing to address issues from a systems perspective amidst growing global concerns.

Modern societal problems require the development of a new scientific way to analyze and address them – one that focuses on the connections between different systems as opposed to the broad buckets into which traditional disciplines dump problems.

The goal of the Center for Systems Science and Engineering (CSSE) at JHU is to further the development of this science of interconnection by using fundamental engineering principles. We want to move systems science away from empirical ad hoc approaches into strategies based on scientifically-grounded analysis using fundamental mathematics, integrating uncertainty, and navigating the conflicting objectives inherent in successful engineering design.

Systems Science is a modeling approach that embraces the dynamic interaction of engineered, human-behavioral, and natural components in time and space. It considers the system as a sum of its parts, where a change in any one part has system-wide ramifications.

As shown below, our research is focused on the areas of Energy, Health, and Transportation, and is upheld by our modeling toolkit. Inspired by optimization — the math of decisions – the toolkit integrates computation, data, and physical science, along with their context in human society, in order to support system function and make our lives safer. Theoretical advancement of network analysis, data science, and computational modeling surround our central pillar of resilience to ensure that we stay grounded to our goal as engineers – ensuring that society can optimally bounce back from any threat.

Using the toolkit, we work across many temporal and spatial scales, from understanding how to immediately deliver care to the next patient, to figuring out optimal energy infrastructure buildout to protect against threats of climate change.

In addition to engineering faculty, CSSE utilizes the expertise of researchers from the schools of Medicine, Public Health, Nursing, Arts and Sciences, Business, and Education as well as members of JHU’s Applied Physics Laboratory and the Center for Governance Excellence. We have a host of collaborations beyond JHU with core partners at the MICA Center for Social Design, DIW Berlin, and R-CITI in Australia.


Graduate students interested in pursuing the Systems Program area should express this interest in their application and be interested in working with one of the Center for System Science and Engineering-affiliated faculty.

Graduate Admissions »

Program Leads:

Affiliated Faculty:

Affiliated Research Groups and Institutes

Systems Relevant Associations



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