Engineering
Design Center

49+
Engineering
design courses
1,900
Engineering design
graduates
36+
Engineering
design-focused
student groups
200+
2024 Design
Day projects

Save the Date! Design Day 2025 is on April 29.

Save the Date! Design Day 2025 is on April 29.

CircuFlow: An Extracorporeal Device to Reduce Afterload During VA-ECMO

Cardiogenic shock (CS) is a life-threatening condition in which the left ventricle (LV) cannot pump blood effectively due to impaired contractility. Venoarterial Extracorporeal Membrane Oxygenation (VA-ECMO) is a life-support technology that removes blood from the venous system, oxygenates it outside the body, and returns it to the arterial system for organ perfusion. VA-ECMO is often the only option for critically ill CS patients who cannot tolerate invasive procedures. Despite its benefits, VA-ECMO has a high mortality rate of nearly 60%, mainly due to increased afterload—the resistance the LV must overcome to eject blood. In patients on VA-ECMO, afterload increases due to continuous retrograde blood flow toward the aortic root. During systole, the compromised LV cannot expel residual blood against this higher pressure, causing blood stasis and LV distension. CircuFlow, a non-invasive device, reduces afterload during systole by creating pulsatile flow and alleviates LV burden, reducing downstream complications.

NeuroFilm: An Implantable Electrospun Substrate for Muscle Stimulation and EMG Recording

Roughly 20% of the world population struggle with musculoskeletal disorders. Typical treatments often target side effects, rather than targeting the atrophied or atypical muscular tissue.

This project proposes an electrode called “NeuroFilm” that aims to aid in muscle repair and reinnervation, as well as monitoring. These electrodes are made of sodium alginate (SA), poly (vinyl alcohol) (PVA), poly (3,4-ethylenedioxythiophene) polystyrene sulfonate (PEDOT:PSS), and glutaraldehyde (GA).

These conductive films are highly fibrous in an isotropic manner. The average diameter of these fibers is around 28 μm. Before the addition of GA, the electrospinning solution shows behavior consistent with the liquid phase, but following the addition of GA, an increase in viscous behavior occurs. The electrochemical properties of this film are comparable to those of a semiconductor.

Both subcutaneous and epimysial implantation levels will be tested, with the expectation that epimysial will outperform due to its direct interface with the muscle in question.

Taliyah

Biomedical Engineering

It is wonderful to watch students from different departments work together to support better engineering design opportunities at Hopkins.

To identify what can satisfy students from every engineering perspective has been both challenging and rewarding, as I’ve learned leading the multidisciplinary student advisory board for the Design Center.

Kareem

Computer Engineering

The First Year Seminar Design CornerStone helped me get exposed to a wide range of engineering disciplines and introduced me to all the makerspace and departments opportunities at Hopkins!

I am excited to take advantage of all the resources available to strengthen my engineering skills.

Alexander

Materials Science and Engineering

Being granted the opportunity to lead a design team has offered me the skillset necessary to apply both engineering and leadership skills in a collaborative environment. I look forward to utilizing these experiences in the medical device space!

 
First-year mechanical engineers’ minicars battle it out on racetrack
Author: Jonathan Deutschman  Photos: Will Kirk The classic paradox asks: What happens…
 
DnATA
Team Members: Julian Chow, Resham Talwar, Varen Talwar Department: Chemical and Biomolecular…