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VRx: TBI Neuromonitoring
- Program: Biomedical Engineering
- Course: EN.580.X12 BME Design Team
- Year: 2025
Project Description:
Mild Traumatic Brain Injury (mTBI) accounts for about 10% of all sports-related injuries each year, posing serious health risks if athletes return to play too soon. Although return-to-play protocols exist, current diagnostic tools like SCAT, ImPACT, and SWAY lack objective biomarkers to accurately guide recovery decisions. Eye movements and pupillary responses have shown promise as potential biomarkers for neurological recovery. Wearable immersive technologies, such as virtual and augmented reality (VR/AR), offer standardized, quantifiable assessments of neurocognitive function. Our team developed a VR-based neuromonitoring system using the Meta Quest Pro 3 to track real-time eye metrics during interactive cognitive and vestibulo-ocular tasks. The system adapts task difficulty while collecting continuous ocular data. Built in Unity, the platform demonstrated reproducible metrics and strong tolerability in healthy subjects. This proof-of-concept highlights the potential of VR to objectively assess oculomotor function, providing a more objective and engaging approach to tracking concussion recovery and enhancing patient safety.
Project Photo:
This image shows a patient using VRx to monitor TBI symptoms, enabling a clinician to make more informed recovery assessments. As the patient engages with the game, objective data from integrated vision, balance, and cognition tests is collected to track recovery progress across the return-to-play timeline.
Student Team Members
- Shalika Subramanian
- Divyansh Lalwani
- Betania Arce
- Pratibha Pradeep
- Aditya Kondepudi
- Arya Kazemnia
- Edmund Tsou
- Isaac Kim
- Jon Browne, MD – Neurology, Johns Hopkins Hospital
- Kemar E. Green, DO – Assistant Professor of Neurology, Johns Hopkins School of Medicine