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Mapping Rosacea and Socioeconomic Inequality Impact Across the United Kingdom: Evidence from a Large-Scale Population-Based Cohort
- Program: Applied Mathematics and Statistics
- Course: EN.553.500 Undergraduate Research
- Year: 2026
Project Description:
Rosacea is a chronic inflammatory skin condition with complex interactions between genetic, environmental, and lifestyle factors. However, little is known about how its distribution varies geographically and socioeconomically across the United Kingdom. We analyzed data from 279,504 UK Biobank participants of unrelated White British ancestry with no personal history of rosacea at baseline. Index of multiple deprivation (IMD) consisted of 7 domains: crime, education, employment, health, housing, income, and living environment. We used logistic regression (general linear model with binomial family) to explore the association between IMD and rosacea risk, adjusting for potential confounders including alcohol intake frequency, skin color, body mass index, smoking status, and sex. We repeated the analyses for each IMD subdomains. Our study provides the first large-scale evidence that socioeconomic factors could be an independent and modifiable risk factor for rosacea.


