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Micro-needle Delivery Device for Gastric Remodeling
- Program: Mechanical Engineering
- Course: EN.530.404 MechE Senior Design
- Year: 2026
Project Description:
Laparoscopic Sleeve Gastrectomy (LSG) is one of the most effective surgical treatments for obesity and related metabolic disorders (Wojciak, 2020), yet it remains an irreversible and moderately invasive procedure associated with risks such as staple-line leaks, postoperative pain, and prolonged recovery. Dr. Akshintala and his team at the Johns Hopkins University School of Medicine are investigating endoscopic methods for gastric remodeling through localized drug delivery. Current endoscopic injectors are limited by single-needle designs, which make drug administration to large gastric regions time-consuming and inefficient. Our senior design project seeks to develop a novel endoscopic microneedle array capable of delivering a sustained-release bleomycin microparticle formulation into the submucosal layer of the stomach.
Project Photo:
The JHUSOM26 team holds an endoscope and their 2mm quad needle injector
