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Sort-A-Cell: Acoustic Sorting for Cellular Injection Therapies
- Program: Biomedical Engineering
- Course: EN.580.X12 BME Design Team
- Year: 2026
Project Description:
Corneal edema is characterized by a blue “cobblestoned” appearance in the eye. If unregulated, canines develop painful ulcers on their ocular surfaces and progressively lose vision, resulting in blindness, and about 90M dogs are at risk of developing this. Corneal transplants are the leading surgical intervention for human cases. However, early successes were unable to be scaled up due to an inability to maintain the cell viability of the donor endothelial layer, as well as a lack of canine donor supply. Cellular injection therapy has been growing as an alternative to corneal transplants due to higher immune compatibility and its ability to serve many canine patients.
Project Photo:
Sort-A-Cell: An Acoustic Microfluidic Cell Sorting Device to purify cell suspensions for use in stem cell injection therapies.
