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Dialyseal: Leak-Resistant Catheter for Peritoneal Dialysis

Project Description:

Peritoneal Dialysis (PD) is the preferred treatment for children with end-stage renal disease (ESRD) as they await kidney transplant. However, the catheter implantation requires a two-week recovery period to mitigate leakage complications, preventing immediate treatment. As a result, many patients are forced to undergo hemodialysis (HD) or continuous renal replacement therapy (CRRT) to maintain solute clearance during their recovery period, which devastates their vasculature and permanently stunts development. We designed a device that can prevent leakage immediately post-catheter insertion, enabling urgent start PD for pediatrics. Our device creates a water-tight seal within 24 hours and offers a simple, robust deployment workflow compatible with minimally invasive catheter insertion techniques.

Project Photo:

The Dialyseal logo depicts a kidney. Two lines represent arteries and veins flowing into the kidney, and a droplet of water signifies the catheter leakage currently faced by peritoneal dialysis patients.

Dialyseal logo. This project created a leak-resistant catheter for peritoneal dialysis in infants, reducing the complications that occur as a result of dialysate leakage during the dialysis process.

Student Team Members

Jayvik Joshi
Saathvik Chandupatla
William Li
Elliot Montgomery
Aarushi Pant
Ty Lockwood
Sophie Tanenbaum
Hayley Tang

Course Faculty

Project Mentors, Sponsors, and Partners

Isam Nasr, MD – Johns Hopkins Medicine; Director, Pediatric Trauma Program