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CryoRay: Top-Down Intralesional Cryotherapy Microneedle

Project Description:

Our device is a single-microneedle attachment that administers liquid nitrogen in a top-down manner. By delivering the cryogen 2-3 mm below the surface of the skin, this novel top-down intralesional cryogen administration allows for keloid tissue remodeling below the surface, resulting in a more effective cryotherapy treatment while still reducing additional skin trauma.

Project Photo:

Needle delivering cryotherapy in a blue ice ball into a skin lesion, with multiple layers of the skin showing.

Microneedle delivering liquid nitrogen to 2-3 mm below the surface of the skin, precisely targeting keloid cells to promote healthy scar remodeling and tissue regeneration.

Project Poster

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Student Team Members

  • Alana Yee
  • Harrsha Kumar
  • Helen Wang
  • Alice Yu
  • Maanya Bajaj
  • Brandon Chong
  • Minh Pham
  • Sindhu Gokaraju

Course Faculty

Project Mentors, Sponsors, and Partners

  • Andrew Tadros, MD, PhD – Johns Hopkins School of Medicine, Department of Dermatology
  • Jihad Alhariri, MD – Johns Hopkins School of Medicine, Department of Dermatology
  • Elise Ng, MD – Johns Hopkins School of Medicine, Department of Dermatology
  • Sashank Reddy, MD, PhD – Johns Hopkins School of Medicine, Department of Plastic and Reconstructive Surgery