Create

Design Project Gallery

Project Search
Search projects by keyword, program, course, or submission year.

Neuro Prima

Project Description:

Neuro Prima is a medical device venture innovating a solution to provide brain decompression and skull reconstruction for severe Traumatic Brain Injury (TBI) patients in a single procedure, as the Standard of Care requires two invasive surgeries. The novel implant eliminates the need for the second surgery, decreasing patient complication rates and dramatically reducing costs for patients and payors.

Project Photo:

Neuro Prima Logo and Name

Neuro Prima – Transforming Brain Decompression and Skull Reconstruction in TBI Patients

Project Poster

Open full size poster in new tab (PDF)

Project Poster Summary:

Neuro Prima is only solution that integrates two highly invasive and complex surgeries into a single one. Our novel implant delivers both clinical and economic value to all key stakeholders—patients, providers, and healthcare facilities. By addressing this critical need, we are unlocking a significant market opportunity. Our team has developed a robust business model and a well-defined go-to-market strategy to successfully navigate the preclinical and clinical phases. With a clear path to commercialization, Neuro Prima is positioned to create substantial value throughout the development journey.

Course Faculty

  • Youseph Yazdi

Project Mentors, Sponsors, and Partners

  • Center of Bioengineering Innovation & Design (CBID)

Project Video

Traumatic brain injury (TBI) is a leading cause of death and disability worldwide, with 10-20% of patients developing life-threatening elevated intracranial pressure (ICP). The Standard of Care for this life-threatening condition is a two-procedure intervention – decompressive craniectomy (DC) followed by a cranioplasty several months later – both of which are highly invasive surgeries that carry significant length of stay, cost, and complications around 35% for cranioplasty. This two-procedure, staged approach necessitates an extensive treatment period, imposing substantial financial burdens on both patients and payors, and demanding a complex recovery process.