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Increasing the Safety of Percutaneous Lung Biopsies

Team: Advanced BME Design Team: PneuTech

Project Description:

A percutaneous core needle lung biopsy is a minimally invasive procedure by which a sample of abnormal lung tissue is obtained through a needle inserted directly into the targeted site of the lung using imaging guidance.The most common complication during this procedure is pneumothorax, a collapsed lung, which occurs in 1 in 5 patients. With over 100,000 procedures performed in the United States alone, pneumothorax contributes to over $120 million in annual hospital costs. Thus, there is a critical need to improve the safety of percutaneous lung biopsies. The current standard of care utilizes a straight needle guided by computed tomography (CT), making it a challenge to direct the needle to the target site while navigating around critical structures, such as major blood vessels, airways, and ribs (Figure 2). Therefore, additional pleural punctures within a single biopsy or a repeat biopsy may be necessary to obtain an adequate sample, increasing the likelihood of pneumothorax. Our solution addresses these issues via a novel needle system equipped with the ability to access any target site in any location while minimizing the number of pleural punctures. By enabling safer high-yield lung biopsy procedures, our device has the potential to revolutionize the lung biopsy space.

Project Photo:

Current straight lung biopsy needle is unable to reach the target behind a rib in just one pleural puncture.

Current straight lung biopsy needle is unable to reach the target behind a rib in just one pleural puncture.

Student Team Members

Katia Kovrizhkin
Sean Darcy
Ashley Tsang
Jacob Desman
Deborah Weidman
Tatiana Pereira
Gohta Aihara

Course Faculty

Project Mentors, Sponsors, and Partners

Clinical Mentor: Dr. Robert Liddell, Ph.D.
Faculty Mentor: Shababa Matin
Dr. Harjit Singh, M.D.
Rich Middlestadt
Dr. Supriya Munshaw, Ph.D.
Bibhav Poudel
Dr. Kimberley Studeman, M.D.
Ian McLane
Sarah Lee