Faculty

Laurent Younes

Professor & Chair

Research Interests

  • Statistical Properties of Markov Random Fields
  • Image Analysis
  • Deformation Analysis
  • Shape Recognition

Laurent Younes is a professor and chair of the Department of Applied Mathematics and Statistics. His research focuses on statistical properties of Markov Random Fields; image analysis; deformation analysis; and shape recognition. He earned his doctorate at the Université Paris-Sorbonne.

Education
  • Ph.D. 1988, UNIVERSITY OF PARIS I-SORBONNE
Experience
  • 2014 - Present:  Chairman, Unspecified
Awards
  • 2015:  Fellow of the Institute for Mathematical Statistics
Journal Articles
  • Miller MI, Arguillère S, Tward DJ, Younes L (2018).  Computational anatomy and diffeomorphometry: A dynamical systems model of neuroanatomy in the soft condensed matter continuum.  Wiley Interdisciplinary Reviews: Systems Biology and Medicine.  10(6).
  • Wu D, Faria AV, Younes L, Ross CA, Mori S, Miller MI (2018).  Whole-brain segmentation and change-point analysis of anatomical brain mri—application in premanifest huntington's disease.  Journal of Visualized Experiments.  2018(136).
  • Dinalankara W, Ke Q, Xu Y, Ji L, Pagane N, Lien A, Matam T, Fertig EJ, Price ND, Younes L, Marchionni L, Geman D (2018).  Digitizing omics profiles by divergence from a baseline.  Proceedings of the National Academy of Sciences of the United States of America.  115(18).
  • Tang X, Ross CA, Johnson H, Paulsen JS, Younes L, Albin RL, Ratnanather JT, Miller MI (2018).  Regional subcortical shape analysis in premanifest Huntington's disease.  Human Brain Mapping.
  • Wu D, Faria AV, Younes L, Mori S, Brown T, Johnson H, Paulsen JS, Ross CA, Miller MI (2017).  Mapping the order and pattern of brain structural MRI changes using change-point analysis in premanifest Huntington's disease.  Human Brain Mapping.  38(10).
  • Tang X, Miller MI, Younes L (2017).  Biomarker change-point estimation with right censoring in longitudinal studies.  Annals of Applied Statistics.  11(3).
  • Staneva V, Younes L (2017).  Learning Shape Trends: Parameter Estimation in Diffusions on Shape Manifolds.  IEEE Computer Society Conference on Computer Vision and Pattern Recognition Workshops.  2017-July.
  • Tward D, Miller M, Trouvé A, Younes L (2017).  Parametric Surface Diffeomorphometry for Low Dimensional Embeddings of Dense Segmentations and Imagery.  IEEE Transactions on Pattern Analysis and Machine Intelligence.  39(6).
  • Dirlikov B, Younes L, Nebel MB, Martinelli MK, Tiedemann AN, Koch CA, Fiorilli D, Bastian AJ, Denckla MB, Miller MI, Mostofsky SH (2017).  Novel automated morphometric and kinematic handwriting assessment: A validity study in children with ASD and ADHD.  Journal of Occupational Therapy, Schools, and Early Intervention.  10(2).
  • Tang X, Albert M, Miller MI, Younes L (2016).  Change point estimation of the hippocampal volumes in Alzheimer's disease.  Proceedings - 2016 13th Conference on Computer and Robot Vision, CRV 2016.
  • Arguillère S, Miller MI, Younes L (2016).  Diffeomorphic surface registration with atrophy constraints.  SIAM Journal on Imaging Sciences.  9(3).
  • Richardson CL, Younes L (2016).  Metamorphosis of images in reproducing kernel Hilbert spaces.  Advances in Computational Mathematics.  42(3).
  • Soldan A, Pettigrew C, Cai Q, Wang MC, Moghekar AR, O'Brien RJ, Selnes OA, Albert MS, Rodzon B, Gottesman R, Sacktor N, McKhann G, Turner S, Farrington L, Grega M, Rudow G, D'Agostino D, Rudow S, Miller M, Mori S, Ratnanather T, Brown T, Chi H, Kolasny A, Oishi K, Reigel T, Younes L, Spangler A, Scherer R, Shade D, Ervin A, Jones J, Toepfner M, Parlett L, Patterson A, Mohammed A, Lu D, Troncoso J, Crain B, Pletnikova O, Fisher K (2016).  Hypothetical preclinical Alzheimer disease groups and longitudinal cognitive change.  JAMA Neurology.  73(6).
  • Ardekani S, Jain S, Sanzi A, Corona-Villalobos CP, Abraham TP, Abraham MR, Zimmerman SL, Wu KC, Winslow RL, Miller MI, Younes L (2016).  Shape analysis of hypertrophic and hypertensive heart disease using MRI-based 3D surface models of left ventricular geometry.  Medical Image Analysis.  29.
  • Jain S, Salimpour Y, Younes L, Smith G, Mari Z, Sossi V, Rahmim A (2016).  Application of pattern recognition framework for quantification of Parkinson's disease in DAT SPECT imaging.  2014 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2014.
  • Arguillère S, Trélat E, Trouvé A, Younes L (2016).  Registration of multiple shapes using constrained optimal control.  SIAM Journal on Imaging Sciences.  9(1).
  • Mittal R, Seo JH, Vedula V, Choi YJ, Liu H, Huang HH, Jain S, Younes L, Abraham T, George RT (2016).  Computational modeling of cardiac hemodynamics: Current status and future outlook.  Journal of Computational Physics.  305.
  • Ardekani S, Jain S, Sanzi A, Corona-Villalobos CP, Abraham TP, Abraham MR, Zimmerman SL, Wu KC, Winslow RL, Miller M, Younes L (2016).  Shape analysis of hypertrophic and hypertensive heart disease using MRI-based 3D surface models of left ventricular geometry.  Medical image analysis.  29.  12-23.
  • Arguillère S, Miller M, Younes L (2016).  Diffeomorphic surface registration with atrophy constraints.  SIAM Journal Imaging Science.  9(3).
  • Tward D, Miller M, Trouve A, Younes E (2016).  Parametric surface diffeomorphometry for low dimensional embeddings of dense segmentations and imagery.  IEEE transactions on pattern analysis and machine intelligence.
  • Faria AV, Ratnanather JT, Tward DJ, Lee DS, Van Den Noort F, Wu D, Brown T, Johnson H, Paulsen JS, Ross CA, Younes L, Miller MI (2016).  Linking white matter and deep gray matter alterations in premanifest Huntington disease.  NeuroImage: Clinical.  11.
  • Richardson CL, Younes E (2016).  Metamorphosis of images in reproducing kernel Hilbert spaces.  Advances in Computational Mathematics.  42(3).  573-603.
  • Arguillere S, Trélat E, Trouvé A, Younes E (2016).  Registration of Multiple Shapes using Constrained Optimal Control.  SIAM Journal on Imaging Sciences.  9(1).  344-385.
  • Mittal R, Seo JH, Vedula V, Choi YJ, Liu H, Huang HH, Jain S, Younes L, Abraham T, George RT (2016).  Computational modeling of cardiac hemodynamics: Current status and future outlook.  Journal of Computational Physics.  305.  1065-1082.
  • Faria AV, Ratnanather J, Tward DJ, Lee DS, Van Den Noort F, Wu D, Brown T, Johnson H, Paulsen JS, Ross CA, Younes E, Miller M (2016).  Linking white matter and deep gray matter alterations in premanifest Huntington disease.  NeuroImage: Clinical.  11.  450-460.
  • Miller MI, Trouvé A, Younes L (2015).  Hamiltonian Systems and Optimal Control in Computational Anatomy: 100 Years since D'Arcy Thompson.  Annual Review of Biomedical Engineering.  17.
  • Vedula V, George R, Younes L, Mittal R (2015).  Hemodynamics in the left atrium and its effect on ventricular flow patterns.  Journal of Biomechanical Engineering.  137(11).
  • Geman D, Ochs M, Price ND, Tomasetti C, Younes L (2015).  An argument for mechanism-based statistical inference in cancer.  Human Genetics.  134(5).
  • Geman D, Geman S, Hallonquist N, Younes L (2015).  Visual Turing test for computer vision systems.  Proceedings of the National Academy of Sciences of the United States of America.  112(12).
  • Miller MI, Younes L, Ratnanather JT, Brown T, Trinh H, Lee DS, Tward D, Mahon PB, Mori S, Albert M (2015).  Amygdalar atrophy in symptomatic Alzheimer's disease based on diffeomorphometry: The BIOCARD cohort.  Neurobiology of Aging.  36(S1).
  • Arguillère S, Trélat E, Trouvé A, Younes L (2015).  Shape deformation analysis from the optimal control viewpoint.  Journal des Mathematiques Pures et Appliquees.  104(1).
  • Soldan A, Pettigrew C, Lu Y, Wang MC, Selnes O, Albert M, Brown T, Ratnanather JT, Younes L, Miller MI, Rodzon B, Gottesman R, Sacktor N, McKhann G, Turner S, Farrington L, Grega M, D'Agostino D, Feagen S, Dolan D, Dolan H, Mori S, Kolasny A, Oishi K, Schneider W, O'Brien R, Moghekar A, Spangler A, Scherer R, Meinert C, Shade D, Ervin A, Jones J, Toepfner M, Parlett L, Patterson A, Lassiter L, Cai Q, Troncoso J, Crain B, Pletnikova O, Rudow G, Fisher K, Cernansky J, Holtzman D, Knopman D, Kukull W, McArdle J, Buckholtz N, Hsiao J, Ryan L, Evans J (2015).  Relationship of medial temporal lobe atrophy, APOE genotype, and cognitive reserve in preclinical Alzheimer's disease.  Human Brain Mapping.  36(7).
  • Mahon PB, Lee DS, Trinh H, Tward D, Miller MI, Younes L, Barta PE, Ratnanather JT (2015).  Morphometry of the amygdala in schizophrenia and psychotic bipolar disorder.  Schizophrenia Research.  164(1-3).
  • Tang X, Holland D, Dale AM, Younes L, Miller MI (2015).  Baseline shape diffeomorphometry patterns of subcortical and ventricular structures in predicting conversion of mild cognitive impairment to Alzheimer's disease.  Journal of Alzheimer's Disease.  44(2).
  • Tang X, Holland D, Dale AM, Younes L, Miller MI (2015).  The diffeomorphometry of regional shape change rates and its relevance to cognitive deterioration in mild cognitive impairment and Alzheimer's disease.  Human Brain Mapping.  36(6).
  • Miller MI, Ratnanather JT, Tward DJ, Brown T, Lee DS, Ketcha M, Mori K, Wang MC, Mori S, Albert MS, Younes L, Rodzon B, Selnes O, Gottesman R, Sacktor N, McKhann G, Turner S, Farrington L, Grega M, D'Agostino D, Feagen S, Dolan D, Dolan H, Kolasny A, Schneider W, O'Brien R, Moghekar A, Meehan R, Scherer R, Meinert C, Shade D, Ervin A, Jones J, Toepfner M, Parlett L, Patterson A, Lassiter L, Li S, Lu Y, Troncoso J, Crain B, Pletnikova O, Rudow G, Fisher K (2015).  Network neurodegeneration in Alzheimer's disease via MRI based shape diffeomorphometry and high-field atlasing.  Frontiers in Bioengineering and Biotechnology.  3(MAY).
  • Miller M, Trouvé A, Younes L (2015).  Hamiltonian Systems and Optimal Control in Computational Anatomy: 100 Years Since D'Arcy Thompson.  Annual review of biomedical engineering.  17.  447-509.
  • Geman D, Geman S, Hallonquist N, Younes L (2015).  Visual turing test for computer vision systems.  Proceedings of the National Academy of Sciences.  112(12).  3618-3623.
  • Arguillere S, Trélat E, Trouvé A, Younes L (2015).  Multiple shape registration using constrained optimal control.  SIAM Journal Imaging Science.
  • Vedula V, George R, Younes L, Mittal R (2015).  Hemodynamics in the left atrium and its effect on ventricular flow patterns.  Journal of biomechanical engineering.  137(11).  111003.
  • Tang X, Holland D, Dale AM, Younes L, Miller M (2015).  The diffeomorphometry of regional shape change rates and its relevance to cognitive deterioration in mild cognitive impairment and Alzheimer's disease.  Human brain mapping.  36(6).  2093-2117.
  • Arguillere S, Trélat E, Trouvé A, Younes L (2015).  Shape deformation analysis from the optimal control viewpoint.  Journal de Mathématiques Pures et Appliquées.  104(1).  139-178.
  • Tang X, Holland D, Dale AM, Younes L, Miller M (2015).  Baseline shape diffeomorphometry patterns of subcortical and ventricular structures in predicting conversion of mild cognitive impairment to Alzheimer's disease..  Journal of Alzheimer's disease : JAD.  44(2).  599-611.
  • Miller M, Younes L, Ratnanather J, Brown T, Trinh H, Lee D, Tward D, Mahon PB, Mori S, Albert M (2015).  Amygdalar atrophy in symptomatic Alzheimer's disease based on diffeomorphometry: the BIOCARD cohort..  Neurobiology of aging.  36 Suppl 1.  S3-S10.
  • Soldan A, Pettigrew C, Lu Y, Wang M, Selnes O, Albert M, Brown T, Ratnanather J, Younes L, Miller M (2015).  Relationship of medial temporal lobe atrophy, APOE genotype, and cognitive reserve in preclinical Alzheimer's disease.  Human brain mapping.  36(7).  2826-2841.
  • Miller M, Ratnanather J, Tward DJ, Brown T, Lee DS, Ketcha M, Mori K, Wang M, Mori S, Albert MS, Younes L (2015).  Network neurodegeneration in Alzheimer's disease via MRI based shape diffeomorphometry and high-field atlasing.  Frontiers in bioengineering and biotechnology.  3.
  • Mahon PB, Lee DS, Trinh H, Tward D, Miller M, Younes L, Barta P, Ratnanather J (2015).  Morphometry of the amygdala in schizophrenia and psychotic bipolar disorder.  Schizophrenia research.  164(1).  199-202.
  • Geman D, Ochs M, Price ND, Tomasetti C, Younes L (2014).  An argument for mechanism-based statistical inference in cancer..  Human genetics.
  • Murawski AM, Gurbani S, Harper JS, Klunk M, Younes L, Jain SK, Jedynak BM (2014).  Imaging the evolution of reactivation pulmonary tuberculosis in mice using 18F-FDG PET.  Journal of Nuclear Medicine.  55(10).
  • Younes L, Ratnanather JT, Brown T, Aylward E, Nopoulos P, Johnson H, Magnotta VA, Paulsen JS, Margolis RL, Albin RL, Miller MI, Ross CA, Wassink T, Cross S, Kimble M, Ryan P, Epping EA, Chiu E, Yastrubetskaya O, Preston J, Goh A, Psych D, Antonopoulos S, Loi S, Chua P, Komiti A, Raymond L, Decolongon J, Varvaris M, Mallonee WM, Suter G, Samii A, Macaraeg A, Jones R, Wood-Siverio C, Factor SA, Testa C, Barker RA, Mason S, McCusker E, Griffith J, Loy C, Gunn D, Orth M, Sübmuth S, Barth K, Trautmann S, Quaid K, Wesson M, Wojcieszek J, Guttman M, Sheinberg A, Karmalkar I, Perlman S, Clemente B, Geschwind MD, Kang G, Satris G, Warner T, Burrows M, Rosser A, Price K, Hunt S, Marshall F, Chesire A, Wodarski M, Hickey C, Panegyres P, Lee J, Andrew S, Perlmutter J, Barton S, Schmidt A, Miedzybrodzka Z, Rae D, D'Alessandro M, Craufurd D, Bek J, Howard E, Mazzoni P, Marder K, Wasserman P, Kumar R, Erickson D, Wheelock V, Tempkin T, Kjer L, Martin W, King P, Wieler M, Sran S, Suchowersk...Danzer P (2014).  Regionally selective atrophy of subcortical structures in prodromal HD as revealed by statistical shape analysis.  Human Brain Mapping.  35(3).
  • Staneva V, Younes L (2014).  Modeling and estimation of shape deformation for topology-preserving object tracking.  SIAM Journal on Imaging Sciences.  7(1).
  • Tward D, Jovicich J, Soricelli A, Frisoni G, Trouvé A, Younes L, Miller M (2014).  Improved reproducibility of neuroanatomical definitions through diffeomorphometry and complexity reduction.  Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics).  8679.
  • Jain S, Tward DJ, Lee DS, Kolasny A, Brown T, Ratnanather JT, Miller MI, Younes L (2014).  Computational anatomy gateway: Leveraging XSEDE computational resources for shape analysis.  ACM International Conference Proceeding Series.
  • Richardson CL, Younes E (2014).  Metamorphosis of Images in Reproducing Kernel Hilbert Spaces.  arXiv preprint arXiv:1409.6573.
  • Tang X, Holland D, Dale AM, Younes L, Miller MI (2014).  Shape abnormalities of subcortical and ventricular structures in mild cognitive impairment and Alzheimer's disease: Detecting, quantifying, and predicting.  Human Brain Mapping.  35(8).
  • Younes L, Albert M, Miller MI (2014).  Inferring changepoint times of medial temporal lobe morphometric change in preclinical Alzheimer's disease.  NeuroImage: Clinical.  5.
  • Ardekani S, Gunter G, Jain S, Weiss RG, Miller MI, Younes L (2014).  Estimating dense cardiac 3D motion using sparse 2D tagged MRI cross-sections.  2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2014.
  • Younes L, Albert M, Miller M (2014).  Inferring changepoint times of medial temporal lobe morphometric change in preclinical Alzheimer's disease.  NeuroImage: Clinical.
  • Arguillere S, Trélat E, Trouvé A, Younes E (2014).  Shape deformation and optimal control.  ESAIM: Proceedings and Surveys.  45.  300-307.
  • Gorospe G, Younes L, Tung L, Vidal R (2013).  A metamorphosis distance for embryonic cardiac action potential interpolation and classification..  Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention.  16(Pt 1).
  • Simcha DM, Younes L, Aryee MJ, Geman D (2013).  Identification of direction in gene networks from expression and methylation.  BMC Systems Biology.  7.
  • Miller MI, Younes L, Ratnanather JT, Brown T, Trinh H, Postell E, Lee DS, Wang MC, Mori S, O'Brien R, Albert M (2013).  The diffeomorphometry of temporal lobe structures in preclinical Alzheimer's disease.  NeuroImage: Clinical.  3.
  • Gorospe G, Younes L, Tung L, Vidal R (2013).  A metamorphosis distance for embryonic cardiac action potential interpolation and classification.  Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics).  8149 LNCS(PART 1).
  • Tward DJ, Ma J, Miller MI, Younes L (2013).  Robust diffeomorphic mapping via geodesically controlled active shapes.  International Journal of Biomedical Imaging.  2013.
  • Richardson CL, Younes L (2013).  Computing metamorphoses between discrete measures.  Journal of Geometric Mechanics.  5(1).
  • Jain A, Younes L (2013).  A kernel class allowing for fast computations in shape spaces induced by diffeomorphisms.  Journal of Computational and Applied Mathematics.  245(1).
  • Sánchez-Vega F, Eisner J, Younes L, Geman D (2013).  Learning multivariate distributions by competitive assembly of marginals.  IEEE Transactions on Pattern Analysis and Machine Intelligence.  35(2).
  • Vadakkumpadan F, Trayanova N, Younes L, Wu KC (2012).  Left-ventricular shape analysis for predicting sudden cardiac death risk.  Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS.
  • Vadakkumpadan F, Trayanova N, Younes L, Wu KC (2012).  Left-ventricular shape analysis for predicting sudden cardiac death risk..  Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference.
  • Younes L (2012).  Constrained Diffeomorphic Shape Evolution.  Foundations of Computational Mathematics.  12(3).
  • Sánchez-Vega F, Eisner J, Younes E, Geman D (2012).  Learning Multivariate Distributions by Competitive Assembly of Marginals.  IEEE Transactions on Pattern Analysis and Machine Intelligence.  99.
  • Ardekani S, Jain A, Jain S, Abraham TP, Abraham MR, Zimmerman S, Winslow RL, Miller MI, Younes L (2012).  Matching sparse sets of cardiac image cross-sections using large deformation diffeomorphic metric mapping algorithm.  Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics).  7085 LNCS.
  • Qiu A, Younes L, Miller MI (2012).  Principal component based diffeomorphic surface mapping.  IEEE Transactions on Medical Imaging.  31(2).
  • Younes L (2012).  Spaces and manifolds of shapes in computer vision: An overview.  Image and Vision Computing.  30(6-7).
  • Oishi K, Akhter K, Mielke M, Ceritoglu C, Zhang J, Jiang H, Li X, Younes L, Miller MI, van Zijl PCM, Albert M, Lyketsos CG, Mori S (2011).  Multi-modal MRI analysis with disease-specific spatial filtering: Initial testing to predict mild cognitive impairment patients who convert to Alzheimer's disease.  Frontiers in Neurology.  AUG.
  • Reading SAJ, Oishi K, Redgrave GW, Mcentee J, Shanahan M, Yoritomo N, Younes L, Mori S, Miller MI, Van Zijl P, Margolis RL, Ross CA (2011).  Diffuse Abnormality of Low to Moderately Organized White Matter in Schizophrenia.  Brain Connectivity.  1(6).
  • Du J, Younes L, Qiu A (2011).  Whole brain diffeomorphic metric mapping via integration of sulcal and gyral curves, cortical surfaces, and images.  NeuroImage.  56(1).
  • Yörük E, Ochs MF, Geman D, Younes L (2011).  A comprehensive statistical model for cell signaling.  IEEE/ACM Transactions on Computational Biology and Bioinformatics.  8(3).
  • Vidal C, Beggs D, Younes L, Jain SK, Jedynak B (2011).  Incorporating user input in template-based segmentation.  Proceedings - International Symposium on Biomedical Imaging.
  • Arrate F, Tilak Ratnanather J, Younes L (2010).  Diffeomorphic active contours.  SIAM Journal on Imaging Sciences.  3(2).
  • Ma J, Miller MI, Younes L (2010).  A bayesian generative model for surface template estimation.  International Journal of Biomedical Imaging.  2010.
  • Allassonnière S, Younes L (2010).  A stochastic algorithm for probabilistic independent component analysis.  Annals of Applied Statistics.  4(1).
  • Ardekani S, Weiss RG, Lardo AC, George RT, Lima JAC, Wu KC, Miller MI, Winslow RL, Younes L (2009).  Cardiac motion analysis in ischemic and non-ischemic cardiomyopathy using parallel transport.  Proceedings - 2009 IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI 2009.
  • Qiu A, Wang L, Younes L, Harms MP, Ratnanather JT, Miller MI, Csernansky JG (2009).  Neuroanatomical asymmetry patterns in individuals with schizophrenia and their non-psychotic siblings.  NeuroImage.  47(4).
  • Ceritoglu C, Oishi K, Li X, Chou MC, Younes L, Albert M, Lyketsos C, van Zijl PCM, Miller MI, Mori S (2009).  Multi-contrast large deformation diffeomorphic metric mapping for diffusion tensor imaging.  NeuroImage.  47(2).
  • Ziane R, Younes L (2009).  Design of a program for straightening standard television pictures taken from the stands. A preliminary stage to the kinematic study of team sport playing actions.  Science et Motricite.  66(1).
  • Ardekani S, Weiss RG, Lardo AC, George RT, Lima JAC, Wu KC, Miller MI, Winslow RL, Younes L (2009).  Computational Method for Identifying and Quantifying Shape Features of Human Left Ventricular Remodeling.  Annals of Biomedical Engineering.  37(6).
  • Chou HF, Younes L (2009).  Smoothing fields of frames using conjugate norms on reproducing kernel hilbert spaces.  Proceedings of SPIE - The International Society for Optical Engineering.  7246.
  • Younes L, Arrate F, Miller MI (2009).  Evolutions equations in computational anatomy..  NeuroImage.  45(1 Suppl).
  • Qiu A, Albert M, Younes L, Miller MI (2009).  Time sequence diffeomorphic metric mapping and parallel transport track time-dependent shape changes..  NeuroImage.  45(1 Suppl).
  • Zhang W, Li X, Zhang J, Luft A, Hanley DF, van Zijl P, Miller MI, Younes L, Mori S (2009).  Landmark-referenced voxel-based analysis of diffusion tensor images of the brainstem white matter tracts. Application in patients with middle cerebral artery stroke.  NeuroImage.  44(3).
  • Holm DD, Trouvé A, Younes L (2009).  The Euler-Poincaré theory of metamorphosis.  Quarterly of Applied Mathematics.  67(4).
  • Vidal C, Hewitt J, Davis S, Younes L, Jain S, Jedynak B (2009).  Template registration with missing parts: Application to the segmentation of M. tuberculosis infected lungs.  Proceedings - 2009 IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI 2009.
  • Chou HF, Younes L (2009).  Smoothing directional vector fields using dual norms.  SIAM Journal on Imaging Sciences.  2(1).
  • Glaunès J, Qiu A, Miller MI, Younes L (2008).  Large deformation diffeomorphic metric curve mapping.  International Journal of Computer Vision.  80(3).
  • Younes L, Qiu A, Winslow RL, Miller MI (2008).  Transport of relational structures in groups of diffeomorphisms.  Journal of Mathematical Imaging and Vision.  32(1).
  • Ma J, Miller MI, Trouvé A, Younes L (2008).  Bayesian template estimation in computational anatomy.  NeuroImage.  42(1).
  • Qiu A, Younes L, Miller MI, Csernansky JG (2008).  Parallel transport in diffeomorphisms distinguishes the time-dependent pattern of hippocampal surface deformation due to healthy aging and the dementia of the Alzheimer's type.  NeuroImage.  40(1).
  • Qiu A, Younes L, Miller MI (2008).  Intrinsic and extrinsic analysis in computational anatomy.  NeuroImage.  39(4).
  • Huang H, Yamamoto A, Hossain MA, Younes L, Mori S (2008).  Quantitative cortical mapping of fractional anisotropy in developing rat brains.  Journal of Neuroscience.  28(6).
  • Younes L, Michor PW, Shah J, Mumford D (2008).  A metric on shape space with explicit geodesics.  Atti della Accademia Nazionale dei Lincei, Classe di Scienze Fisiche, Matematiche e Naturali, Rendiconti Lincei Matematica e Applicazioni.  19(1).
  • Sirong Z, Younes L, Zweck J, Ratnanather JT (2007).  Diffeomorphic surface flows: A novel method of surface evolution.  SIAM Journal on Applied Mathematics.  68(3).
  • Beg MF, Dickie R, Golds G, Younes L (2007).  Consistent realignment of 3D diffusion tensor MRI eigenvectors.  Progress in Biomedical Optics and Imaging - Proceedings of SPIE.  6512(PART 3).
  • Qiu A, Younes L, Wang L, Ratnanather JT, Gillepsie SK, Kaplan G, Csernansky J, Miller MI (2007).  Combining anatomical manifold information via diffeomorphic metric mappings for studying cortical thinning of the cingulate gyrus in schizophrenia.  NeuroImage.  37(3).
  • Wang L, Beg F, Ratnanather T, Ceritpglu C, Younes L, Morris JC, Csernansky JG, Miller MI (2007).  Large deformation diffeomorphism and momentum based hippocampal shape discrimination in dementia of the alzheimer type.  IEEE Transactions on Medical Imaging.  26(4).
  • Gadat S, Younes L (2007).  A stochastic algorithm for feature selection in pattern recognition.  Journal of Machine Learning Research.  8.
  • Younes L (2007).  Jacobi fields in groups of diffeomorphisms and applications.  Quarterly of Applied Mathematics.  65(1).
  • Cao Y, Miller MI, Mori S, Winslow RL, Younes L (2006).  Diffeomorphic matching of diffusion tensor images.  Proceedings of the IEEE Computer Society Conference on Computer Vision and Pattern Recognition.  2006.
  • Garcin L, Younes L (2006).  Geodesic matching with free extremities.  Journal of Mathematical Imaging and Vision.  25(3).
  • Younes L (2006).  Combining geodesic interpolating splines and affine transformations.  IEEE Transactions on Image Processing.  15(5).
  • Feldman T, Younes L (2006).  Homeostatic image perception: An artificial system.  Computer Vision and Image Understanding.  102(1).
  • Miller MI, Trouvé A, Younes L (2006).  Geodesic shooting for computational anatomy.  Journal of Mathematical Imaging and Vision.  24(2).
  • Helm PA, Younes L, Beg MF, Ennis DB, Leclercq C, Faris OP, McVeigh E, Kass D, Miller MI, Winslow RL (2006).  Evidence of structural remodeling in the dyssynchronous failing heart.  Circulation Research.  98(1).
  • Cao Y, Miller MI, Winslow RL, Younes L (2005).  Large deformation diffeomorphic metric mapping of fiber orientations.  Proceedings of the IEEE International Conference on Computer Vision.  II.
  • Garcin L, Younes L (2005).  Geodesic image matching: A wavelet based energy minimization scheme.  Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics).  3757 LNCS.
  • Allassonnière S, Trouvé A, Younes L (2005).  Geodesic shooting and diffeomorphic matching via textured meshes.  Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics).  3757 LNCS.
  • Trouvé A, Younes L (2005).  Local geometry of deformable templates.  SIAM Journal on Mathematical Analysis.  37(1).
  • Helm PA, Tseng HJ, Younes L, McVeigh ER, Winslow RL (2005).  Ex vivo 3D diffusion tensor imaging and quantification of cardiac laminar structure.  Magnetic Resonance in Medicine.  54(4).
  • Cao Y, Miller MI, Winslow RL, Younes L (2005).  Large deformation diffeomorphic metric mapping of vector fields.  IEEE Transactions on Medical Imaging.  24(9).
  • Bitouk D, Miller MI, Younes L (2005).  Clutter invariant ATR.  IEEE Transactions on Pattern Analysis and Machine Intelligence.  27(5).
  • Trouvé A, Younes L (2005).  Metamorphoses through lie group action.  Foundations of Computational Mathematics.  5(2).
  • Beg MF, Miller MI, Trouvé A, Younes L (2005).  Computing large deformation metric mappings via geodesic flows of diffeomorphisms.  International Journal of Computer Vision.  61(2).
  • Lu L, Hager GD, Younes L (2005).  A three tiered approach for articulated object action modeling and recognition.  Advances in Neural Information Processing Systems.
  • Guo H, Rangarajan A, Joshi S, Younes L (2004).  Non-rigid registration of shapes via diffeomorphic point matching.  2004 2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano.  1.
  • Garcin L, Rangarajan A, Younes L (2004).  Non rigid registration of shapes via diffeomorphic point matching and clustering.  Proceedings - International Conference on Image Processing, ICIP.  2.
  • Vaillant M, Miller MI, Younes L, Trouvé A (2004).  Statistics on diffeomorphisms via tangent space representations.  NeuroImage.  23(SUPPL. 1).
  • Holm DD, Tilak Ratnanather J, Trouvé A, Younes L (2004).  Soliton dynamics in computational anatomy.  NeuroImage.  23(SUPPL. 1).
  • Glaunes J, Trouvé A, Younes L (2004).  Diffeomorphic matching of distributions: A new approach for unlabelled point-sets and sub-manifolds matching.  Proceedings of the IEEE Computer Society Conference on Computer Vision and Pattern Recognition.  2.
  • Guo H, Rangarajan A, Joshi SC, Younes L (2004).  A new joint clustering and diffeomorphism estimation algorithm for non-rigid shape matching.  IEEE Computer Society Conference on Computer Vision and Pattern Recognition Workshops.  2004-January(January).
  • Miller MI, Trouvé A, Younes L (2003).  The metric spaces, Euler equations, and normal geodesic image motions of computational anatomy.  IEEE International Conference on Image Processing.  2.
  • Beg MF, Miller M, Trouvé A, Younes L (2003).  The Euler-Lagrange equation for interpolating sequence of landmark datasets.  Lecture Notes in Computer Science.  2879(PART 2).
  • Bitouk D, Miller MI, Younes L (2003).  Asymptotic Performance Analysis for Object Recognition in Clutter.  Proceedings of SPIE - The International Society for Optical Engineering.  5094.
  • Beg MF, Miller MI, Trouve A, Younes L (2002).  Computing metrics on anatomical shapes in computational anatomy.  Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings.  2.
  • Bitouk D, Miller MI, Younes L (2002).  Empirically generated metric spaces for ATR in clutter.  Conference Record of the Asilomar Conference on Signals, Systems and Computers.  2.
  • Miller MI, Trouvé A, Younes L (2002).  On the metrics and Euler-Lagrange equations of computational anatomy.  Annual Review of Biomedical Engineering.  4.
  • Beg MF, Miller MI, Trouvé A, Younes L (2002).  Computational anatomy: Computing metrics on anatomical shapes.  Proceedings - International Symposium on Biomedical Imaging.  2002-January.
  • Miller MI, Younes L (2001).  Group actions, homeomorphisms, and matching: A general framework.  International Journal of Computer Vision.  41(1-2).
  • Camion V, Younes L (2001).  Geodesic interpolating splines.  Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics).  2134.
  • Trouvé A, Younes L (2000).  On a class of diffeomorphic matching problems in one dimension.  SIAM Journal on Control and Optimization.  39(4).
  • Younes L (2000).  Calibrating parameters of cost functionals.  Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics).  1843.
  • Bereziat D, Herlin I, Younes L (2000).  Generalized optical flow constraint and its physical interpretation.  Proceedings of the IEEE Computer Society Conference on Computer Vision and Pattern Recognition.  2.
  • Trouvé A, Younes L (2000).  Diffeomorphic matching problems in one dimension: Designing and minimizing matching functionals.  Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics).  1842.
  • Younes L (1999).  Optimal matching between shapes via elastic deformations.  Image and Vision Computing.  17(5).
  • Bereziat D, Herlin I, Younes L (1999).  Motion estimation using a volume conservation hypothesis.  ICASSP, IEEE International Conference on Acoustics, Speech and Signal Processing - Proceedings.  6.
  • Younes L (1998).  Synchronous random fields and image restoration.  IEEE Transactions on Pattern Analysis and Machine Intelligence.  20(4).
  • Younes L (1998).  Stochastic gradient estimation strategies for Markov random fields.  Proceedings of SPIE - The International Society for Optical Engineering.  3459.
  • Younes L (1998).  Computable elastic distances between shapes.  SIAM Journal on Applied Mathematics.  58(2).
  • Azencott R, Wang JP, Younes L (1997).  Texture classification using windowed fourier filters.  IEEE Transactions on Pattern Analysis and Machine Intelligence.  19(2).
  • Béréziat D, Herlin I, Younes L (1997).  Motion detection in meteorological images sequences: Two methods and their comparison.  Proceedings of SPIE - The International Society for Optical Engineering.  3217.
  • Azencott R, Wang JP, Younes L (1997).  Texture classification using windowed Fourier filters.  IEEE Transactions on Pattern Analysis and Machine Intelligence.  19(2).
  • Azencott R, Younes L (1997).  An energy minimization method for matching and comparing structured object representations.  Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics).  1223.
  • Azencott R, Coldefy F, Younes L (1996).  A distance for elastic matching in object recognition.  Proceedings - International Conference on Pattern Recognition.  1.
  • Younes L (1996).  Synchronous Boltzmann machines can be universal approximators.  Applied Mathematics Letters.  9(3).
  • Younes L (1994).  Synchronous image restoration.  Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics).  801 LNCS.
  • Azencott R, Doutriaux A, Younes L (1993).  Synchronous boltzmann machines and curve identification tasks.  Network: Computation in Neural Systems.  4(4).
  • Younes L (1989).  Parametric Inference for imperfectly observed Gibbsian fields.  Probability Theory and Related Fields.  82(4).
Book Chapters
  • Trouvé A, Younes L (2015).  Shape spaces.  Handbook of Mathematical Methods in Imaging: Volume 1, Second Edition.
  • Glaunès J, Trouvé A, Younes L (2006).  Modeling Planar Shape Variation via Hamiltonian flows of curves.  Modeling and Simulation in Science, Engineering and Technology.  (9780817643768).
Conference Proceedings
  • Younes E (2000).  Calibrating Parameters of Cost Functionals in Computer Vision.  ECCV 2000.
Patents
  • Dirlikov B, Miller M, Mostofsky S, Younes E  "Kinematic and morphometric analysis of digitized handwriting tracings", 2015.
  • "Riemannian Diffeomorphic Mapping and Some Applications", Flows, mappings and shapes.  Cambridge, United Kingdom of Great Britain and Northern Ireland (the).  December 12, 2017
  • "What can we learn from large deformation diffeomorphic metric mapping on spaces of rigid bodies?", Shape analysis and computational anatomy.  Cambridge, United Kingdom of Great Britain and Northern Ireland (the).  November 14, 2017
  • "Mechanical Aspects of LDDMM", Applications-Driven Geometric Functional Data Analysis.  October 9, 2017
  • "Hybrid Large Deformation Diffeomorphic Metric Mapping", SIAM conf. Imaging Science.  Pittsburgh Pennsylvania, United States of America (the).  July 14, 2017
  • "Hybrid LDDMM", New Trends in Applied Geometric Mechanics.  Madrid, Spain.  July 4, 2017
  • SSIMA 2016.  July 1, 2016
  • Mathematics of Shape and Applications.  Singapore.  July 1, 2016
  • Biomedical Imaging and Computer Vision.  Singapore.  July 1, 2016
  • ISNPS 2016.  Avignon, France.  June 1, 2016
  • Geometric Analysis in Control and Vision Theory.  Voss, Norway.  May 1, 2016
  • SIAM conference in Imaging Science.  Albuquerque.  May 1, 2016
  • Statistical Analysis of Manifold Data and Beyond.  UK.  April 1, 2016
  • Regular seminar Simon Frazer U..  Vancouver.  August 1, 2015
  • Joint Statistical Meetings.  Seattle.  August 1, 2015
  • SSIMA Imaging Summer School.  Romania.  July 1, 2015
  • Neuroscience summer school.  July 1, 2015
  • Classic and Stochastic Geometric Mechanics.  Lausanne.  June 1, 2015
  • SIAM Conference on Computational Science and Engineering.  Salt Lake City.  March 1, 2015
  • "Image-based flow modeling in a two-chamber model of the left heart", 67th Annual APS DFD Meeting.  San Francisco, California.  November 25, 2014
  • "Statistical studies, Metamorphosis and Cardiac Computational Anatomy: a summary of recent work.", Shape Meeting.  London.  June 1, 2014
  • "Shape Analysis of Cardiac Images", SIAM Conference in Imaging Science.  Hong Kong.  May 1, 2014
  • "Smooth or Singular Metamorphoses for Images and Measures", SIAM Conference in Imaging Science.  Hong Kong.  May 1, 2014
  • "Statistical Shape Analysis in Computational Anatomy", Workshop 2: Morphogenesis, Regeneration, and the Analysis of Shape.  Ohio State.  February 10, 2014
  • "Diffeomorphic Shape Analysis", 14th Annual Winter School in eScience.  Geilo, Norway.  January 18, 2014
  • "Riemannian Metrics on Spaces of Deformable Images and Measures: from Singular to Smooth", Joint Mathematical Meetings.  Baltimore.  January 1, 2014
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