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Recent news reports stated that the National Security Agency has pursued new methods that have allowed the agency to monitor telephone and online communication, encrypted information that was thought to be virtually immune to eavesdropping. What steps can and should computer scientists take in response to this privacy threat? How will the recent revelations affect the future of cryptography—the field of encoding and decoding electronic communication and transmissions for the purposes of privacy, reliability and efficiency?
To address these questions, the Johns Hopkins University Information Security Institute will host an hour-long roundtable discussion, moderated by Anton Dahbura, interim executive director of the Information Security Institute, and Avi Rubin, the institute’s technical director. Other participants will include Johns Hopkins cyber-security experts Matthew Green, Stephen Checkoway and Giuseppe Ateniese.
The event will be streamed live at https://connect.johnshopkins.edu/jhuisicrypto/, and also will be posted online following the event.
NOTE: Seating at this public event will be limited. Members of the media who plan to cover the discussion are asked to RSVP to Phil Sneiderman, email@example.com.
Laurent Younes, professor and chair of the Department of Applied Mathematics and Statistics at Johns Hopkins University, will present “Change Point Estimation of Brain Shape Data in Relation with Alzheimer’s Disease.”
Abstract: The manifestation of an event, such as the onset of a disease, is not always immediate and often requires some time for its repercussions to become observable. Slowly progressing diseases, and in particular neuro-degenerative disorders such as Alzheimer’s disease (AD), fall into this category. The manifestation of such diseases is related to the onset of cognitive or functional impairment and, at the time when this occurs, the disease may have already had been affecting the brain anatomically and functionally for a considerable time. We consider a statistical two-phase regression model in which the change point of a disease biomarker is measured relative to another point in time, such as the manifestation of the disease, which is subject to right-censoring (i.e., possibly unobserved over the entire course of the study). We develop point estimation methods for this model, based on maximum likelihood, and bootstrap validation methods. The effectiveness of our approach is illustrated by numerical simulations, and by the estimation of a change point for atrophy in the context of Alzheimer’s disease, wherein it is related to the cognitive manifestation of the disease. This work is a collaboration with Marilyn Albert, Xiaoying Tang and Michael Miller, and was partially supported by the NIH.
For those who cannot make it to the Homewood campus, the seminar will be video-conferenced to Traylor 709 on the School of Medicine campus.
For those who attend at Homewood, lunch will be provided at noon.
The Institute for NanoBioTechnology Seminar Series will present Vipul Periwal from the National Institutes of Health and his discussion on “Quantitatively predicting the effects of therapeutic intervention in human disease.”
Periwal is a senior investigator at the National Institutes of Health in the Intramural Research Program. His focus is on computational medicine and biological modeling with a goal to use biological modeling to predict systemic responses to perturbations. His current research includes data-driven large-scale biological modeling of disease, model of reactive oxygen species in mitochondria, and adipocyte development and insulin resistance.
Light refreshments will be provided.
The Institute for NanoBioTechnology Summer Seminar Series will present Jay Baraban from the Johns Hopkins School of Medicine and his discussion on “Understanding How a MicroRNA System Affects Synapse Plasticity.”
Baraban, a professor of neuroscience and psychiatry and behavioral sciences at the Johns Hopkins School of Medicine, focuses his research on the neuronal signaling pathways that mediate neuronal morphology and synaptic efficacy, particularly neuronal plasticity induced by environmental stimuli, including drugs. Baraban and his colleagues have identified a protein that changes the strength of a message sent from one nerve to another and which may play a role in addictive behaviors.
The Institute for NanoBioTechnology Summer Seminar Series will present Justin Taraska, from the National Heart, Lung, and Blood Institute, for a discussion on “Understanding the Molecular Topology of the Plasma Membrane.”
Taraska, PI at NHLBI, is a 2012 PECASE recipient, the highest honor bestowed by the U.S. government to outstanding scientists and engineers beginning their independent careers. Taraska studies how vesicles fuse with and are recaptured from the cell surface in excitable cells. He seeks to identify the proteins that control these processes and determine their impact on human health and disease. Focusing on techniques that utilize fluorescence to image the molecular behavior of proteins in parallel with using evanescent field, spectral, and confocal microscopy to image the behavior of individual vesicles in real time.
The Institute for NanoBioTechnology hosts Jerry S.H. Lee for a seminar on “The Center for Strategic Scientific Initiatives: Perspectives on its History, Development and Continuing Mission.”
Lee, Health Sciences Director at NCI’s Center for Strategic Scientific Initiatives (CSSI) provides leadership and input in planning, developing, and implementing rapid strategic scientific and technology initiatives. This includes direct development and application of advanced technologies, creation of new trans-disciplinary teams, and use of available federal funding mechanisms to forge novel partnerships that emphasize innovation and convergence of scientific disciplines. In 2016, Dr. Lee was assigned to the Office of the Vice President to serve as the Deputy Director for Cancer Research and Technology for the White House Cancer Moonshot Task Force.
The Institute for NanoBioTechnology hosts Steven M. Jay, assistant professor at the University of Maryland, College Park, for a seminar on “Uncovering New Insights into Vascular Pharmaceutical Biology and the Design of New Biotherapeutics.”
Steven M. Jay is involved in projects at the interface of vascular and cancer biology, and bioengineering, with the objective of generating new therapies that can be translated to clinical use. His research aims to uncover new biological insights towards the design and development of novel biopharmaceuticals, including proteins and extracellular vesicles (exosomes) through protein engineering for therapeutic vascularization, engineering exosomal nanotechnology for translational therapeutic delivery, and enhancing tissue engineering through drug delivery.