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The Institute for NanoBioTechnology Seminar Series will present Vipul Periwal from the National Institutes of Health and his discussion on “Quantitatively predicting the effects of therapeutic intervention in human disease.”
Periwal is a senior investigator at the National Institutes of Health in the Intramural Research Program. His focus is on computational medicine and biological modeling with a goal to use biological modeling to predict systemic responses to perturbations. His current research includes data-driven large-scale biological modeling of disease, model of reactive oxygen species in mitochondria, and adipocyte development and insulin resistance.
Light refreshments will be provided.
The Institute for NanoBioTechnology Summer Seminar Series will present Jay Baraban from the Johns Hopkins School of Medicine and his discussion on “Understanding How a MicroRNA System Affects Synapse Plasticity.”
Baraban, a professor of neuroscience and psychiatry and behavioral sciences at the Johns Hopkins School of Medicine, focuses his research on the neuronal signaling pathways that mediate neuronal morphology and synaptic efficacy, particularly neuronal plasticity induced by environmental stimuli, including drugs. Baraban and his colleagues have identified a protein that changes the strength of a message sent from one nerve to another and which may play a role in addictive behaviors.
The Institute for NanoBioTechnology Summer Seminar Series will present Justin Taraska, from the National Heart, Lung, and Blood Institute, for a discussion on “Understanding the Molecular Topology of the Plasma Membrane.”
Taraska, PI at NHLBI, is a 2012 PECASE recipient, the highest honor bestowed by the U.S. government to outstanding scientists and engineers beginning their independent careers. Taraska studies how vesicles fuse with and are recaptured from the cell surface in excitable cells. He seeks to identify the proteins that control these processes and determine their impact on human health and disease. Focusing on techniques that utilize fluorescence to image the molecular behavior of proteins in parallel with using evanescent field, spectral, and confocal microscopy to image the behavior of individual vesicles in real time.
The Institute for NanoBioTechnology hosts Jerry S.H. Lee for a seminar on “The Center for Strategic Scientific Initiatives: Perspectives on its History, Development and Continuing Mission.”
Lee, Health Sciences Director at NCI’s Center for Strategic Scientific Initiatives (CSSI) provides leadership and input in planning, developing, and implementing rapid strategic scientific and technology initiatives. This includes direct development and application of advanced technologies, creation of new trans-disciplinary teams, and use of available federal funding mechanisms to forge novel partnerships that emphasize innovation and convergence of scientific disciplines. In 2016, Dr. Lee was assigned to the Office of the Vice President to serve as the Deputy Director for Cancer Research and Technology for the White House Cancer Moonshot Task Force.
The Institute for NanoBioTechnology hosts Steven M. Jay, assistant professor at the University of Maryland, College Park, for a seminar on “Uncovering New Insights into Vascular Pharmaceutical Biology and the Design of New Biotherapeutics.”
Steven M. Jay is involved in projects at the interface of vascular and cancer biology, and bioengineering, with the objective of generating new therapies that can be translated to clinical use. His research aims to uncover new biological insights towards the design and development of novel biopharmaceuticals, including proteins and extracellular vesicles (exosomes) through protein engineering for therapeutic vascularization, engineering exosomal nanotechnology for translational therapeutic delivery, and enhancing tissue engineering through drug delivery.
The Johns Hopkins Department of Biomedical Engineering and Institute for NanoBioTechnology co-host a joint distinguished seminar. Arthur J. Coury, University Distinguished Professor in the Department of Chemical Engineering at Northeastern University, will present “Medical Product Translation: Concept to Market and Beyond with Considerations Along the Way.”
Abstract: Developing regulated medical products through all required stages, whether emanating from academic or industrial sources, has led to the understanding of certain principles required to achieve commercial success. Experiences derived from executing product development protocols have generated a list of dozens of variables that should be considered, including technical, economic, regulatory, even ethical topics, before advancing far in this process. Failure to satisfy one or a few of the “imperatives” generated from such an analysis will most likely prevent achieving a successfully marketed product. In this talk, facts and figures of the medical product “playing field” will be presented. Following this, stages of a typical regulated medical product development plan with pitfalls along the way will be offered. Then, a “case study” of a successful vs. unsuccessful commercialized medical device will be provided and explained in light of the “imperatives.” Finally, a note on the potential value of an academic license to a medical product company will be suggested.
The 3rd Annual INBT Undergraduate Research Symposium will showcase recent undergraduate research. This year’s theme is Innovation Through Engineering. There will be industry representatives and networking opportunities. Diisplays of prototypes will be present along with poster presentations. Lunch will be provided.
The schedule will be as follows:
11:30 am Check in
12 – 1:30 pm 1st Poster Session
2 – 3:30 pm 2nd Poster Session
3:45 pm Awards
The annual Nano-Bio Symposium is INBT’s signature event to showcase our multidisciplinary programs and researchers from across the entire University. The event provides an opportunity to hear presentations by leading scholars in the field, both from Hopkins and other institutions. It also offers a unique opportunity to meet and network with faculty and experts to establish new collaborations.
The annual symposium is hosted by INBT and the Physical Science-Oncology Center. This years theme will be Advanced Biomanufacuring and take place at the Homewood campus in the Glass Pavilion.
The Annual Nano-Bio Symposium is a showcase and celebration of the latest discoveries in nanoscience from our multidisciplinary research teams at the Institute for NanoBioTechnology. It brings students and top scholars from Hopkins, other institutions, and industry together to network, share knowledge and ideas, and foster new collaborations.
The theme for the 2019 Nano-Bio Symposium is Translation of Nano & Bio Research.
Visit inbt.jhu.edu/symposium for more information.