{"id":55460,"date":"2025-11-11T15:53:17","date_gmt":"2025-11-11T20:53:17","guid":{"rendered":"https:\/\/engineering.jhu.edu\/magazine\/?p=55460"},"modified":"2025-11-25T10:12:57","modified_gmt":"2025-11-25T15:12:57","slug":"pathways-to-entrepreneurship","status":"publish","type":"post","link":"https:\/\/engineering.jhu.edu\/magazine\/impact\/pathways-to-entrepreneurship\/","title":{"rendered":"Pathways to Entrepreneurship"},"content":{"rendered":"\n<p class=\"has-text-align-left\">Benefiting society is a prime motivator for many scientists and engineers.&nbsp; A direct way to pursue this aim is via entrepreneurship, where discoveries in the lab can translate to the commercial sector. Yet for many faculty members, finding the time to launch a business, given their myriad other responsibilities, is inherently daunting.<\/p>\n\n\n\n<p>To help navigate the challenges of entrepreneurship at Johns Hopkins, the university established a tech incubator, <a href=\"https:\/\/ventures.jhu.edu\/programs-services\/fastforward\/resources-programs\/\" target=\"_blank\" rel=\"noreferrer noopener\">Johns Hopkins Technology Ventures<\/a> (JHTV), over a decade ago. JHTV guides researchers on whichever path makes the most sense for their particular innovation. The paths available include creating a startup company (often the most readily thought of), as well as obtaining a patent or seeking corporate collaboration and licensing opportunities. \u201cWe work with a lot of faculty to get their ideas out of academia and out into the world,\u201d says <a href=\"https:\/\/ventures.jhu.edu\/bios\/elizabeth-burger\/\" target=\"_blank\" rel=\"noreferrer noopener\">Elizabeth Burger,<\/a> the senior director of strategic initiatives at JHTV. \u201cThrough one or more of the entrepreneurial pathways, we\u2019re here to support faculty on their journey, especially junior faculty who are new to this kind of enterprise.\u201d<\/p>\n\n\n\n<div><div class=\"wp-block-image\">\n<figure class=\"alignright size-medium is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"200\" height=\"300\" src=\"https:\/\/engineering.jhu.edu\/magazine\/wp-content\/uploads\/2025\/11\/JHU9436-200x300.jpg\" alt=\"Photo of Jude Phillip, standing in front of a yellow backdrop.\" class=\"wp-image-55472\" style=\"width:400px\" srcset=\"https:\/\/engineering.jhu.edu\/magazine\/wp-content\/uploads\/2025\/11\/JHU9436-200x300.jpg 200w, https:\/\/engineering.jhu.edu\/magazine\/wp-content\/uploads\/2025\/11\/JHU9436-683x1024.jpg 683w, https:\/\/engineering.jhu.edu\/magazine\/wp-content\/uploads\/2025\/11\/JHU9436-768x1152.jpg 768w, https:\/\/engineering.jhu.edu\/magazine\/wp-content\/uploads\/2025\/11\/JHU9436-1024x1536.jpg 1024w, https:\/\/engineering.jhu.edu\/magazine\/wp-content\/uploads\/2025\/11\/JHU9436-1365x2048.jpg 1365w, https:\/\/engineering.jhu.edu\/magazine\/wp-content\/uploads\/2025\/11\/JHU9436-scaled.jpg 1707w\" sizes=\"auto, (max-width: 200px) 100vw, 200px\" \/><\/figure>\n<\/div><\/div>\n\n\n\n<p>One young faculty member who is working with JHTV to realize the profound potential of his research is <a href=\"https:\/\/engineering.jhu.edu\/faculty\/jude-phillip\/\" target=\"_blank\" rel=\"noreferrer noopener\">Jude Phillip, Engr \u201915<\/a> (PhD), an assistant professor of biomedical engineering who joined Johns Hopkins in 2023. His lab focuses on developing technologies that can predict and modify aging trajectories, overall helping people live healthily into their 70s, 80s, and beyond. \u201cWe\u2019re applying engineering to aging research,\u201d says Phillip. \u201cWe want our work to have an impact on people, whether it be through clinicians or hospital systems or right-to-end users.\u201d<\/p>\n\n\n\n<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\">\n<p>&#8220;Through one or more of the entrepreneurial pathways, we\u2019re here to support faculty on their journey, especially junior faculty who are new to this kind of enterprise.&#8221; \u2014Elizabeth Burger<\/p>\n<\/blockquote>\n\n\n\n<p>Boosting older adults\u2019 welfare is a largely unmet and increasingly dire issue; by the mid-2040s, it\u2019s estimated that more people will be over 60 than under 18 years of age across much of the developed world, including the United States. Given this urgency, Phillip and colleagues are presently exploring all three entrepreneurial pathways. Over the last few years, the researchers have submitted several reports of invention to Johns Hopkins. These discoveries are presently being evaluated for potential patenting or commercial application by JHTV, which meets with Phillip regularly to offer development feedback and strategy.<\/p>\n\n\n\n<p>Meanwhile, companies in the pharmaceutical and venture capital spaces have also begun reaching out to Phillip &nbsp;about possible partnerships, investment, and licensing. In light of such buzz, Phillip and his team are additionally considering creating their own startup, again leveraging JHTV\u2019s expertise. \u201cWe have a lot of ways we can go at this time, and JHTV has been super-instrumental in getting us to this stage,\u201d says Phillip, who serves on the JHTV faculty advisory committee.<\/p>\n\n\n\n<p>One key discovery from Phillip and colleagues is that senescent cells\u2014aged cells that no longer divide and proliferate\u2014are not all the same, as had been thought. Studies have tied the buildup of senescent cells to age-related disease, due to these cells releasing pro-inflammatory molecules that degrade tissue function. Phillip revealed, however, with machine learning and imaging techniques that at least three subtypes of senescent cells exist, only one of which strongly correlates with unhealthy aging.<\/p>\n\n\n\n<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\">\n<p>\u201cWe have a lot of ways we can go at this time, and JHTV has been super instrumental in getting us to this stage.\u201d \u2014Jude Phillip<\/p>\n<\/blockquote>\n\n\n\n<p>Those findings, in turn, have spurred development of screening platforms for gauging how different senescent cell subtypes respond to so-called senolytics\u2014an emerging new drug class that targets senescent cells and could, in theory, lessen the brunt of some age-related maladies. \u201cThe goal here is not to kill all senescent cells, because some have beneficial roles,\u201d says Phillip. \u201cWe just want to kill the bad ones.\u201d Phillip and his colleagues continue to mature their techniques while assessing the most advantageous entrepreneurial approach. In this vein, JHTV has also connected Phillip with alumni entrepreneurs who\u2019ve successfully pushed out companies, as well as hosted lunch-and-learn workshops where businesspeople have shared their startup, patent-filing, and licensing experiences.<\/p>\n\n\n\n<p>\u201cWe\u2019re really excited about what our work could do for the critical challenge of aging populations,\u201d says Phillip.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Securing Next-Generation Communications<\/h2>\n\n\n\n<p>Another junior faculty member walking the entrepreneurial path is <a href=\"https:\/\/engineering.jhu.edu\/faculty\/alex-marder\/\" target=\"_blank\" rel=\"noreferrer noopener\">Alex Marder<\/a>. Like Phillip, he joined Johns Hopkins a couple of years ago. Marder\u2019s research centers on enhancing the security of 5G communications networks, initially for use by the Department of Defense (DoD). 5G is continuing to roll out worldwide, offering much higher speeds and data capacities than today\u2019s 4G. For the federal workforce, though\u2014especially the military\u2014accessing new, public 5G can pose significant security concerns because third-party network infrastructure might contain unknown and untrusted hardware. As a result, sensitive communications could be intercepted by adversaries.<\/p>\n\n\n\n<p>\u201cThe issue is that the DoD needs to be able to use cellphones and other devices, both tactically and not tactically, in military and other settings, and it\u2019s not yet known how to do that securely,\u201d says Marder, who is an assistant professor of computer science. \u201cBut we\u2019ve come up with a solution.\u201d<\/p>\n\n\n\n<p>Marder and colleagues have developed mobile device software that can identify the hardware on cell towers before the device proceeds with data transfer. Rather than trying to fingerprint hardware through physical properties of manufacturing, as prior approaches have explored, Marder\u2019s platform instead observes the behavior of the hardware. That behavior gives telltale signs that reveal the hardware\u2019s maker, helping DoD workers to assess and avoid risks.<\/p>\n\n\n\n<p>\u201cThe phone basically looks at the equipment that lives on the cell tower and even beyond, and gauges if this is equipment we want to be connecting to,\u201d says Marder.<\/p>\n\n\n\n<p>To commercialize the technology, Marder and colleagues created a startup last year called Revelare Networks (pronounced \u201crev-UH-layr,\u201d derived from a Latin word meaning \u201creveal\u201d). The company, supported by DoD funding, has now grown to seven employees and is further implementing Marder\u2019s network visibility and reliability tools. Field testing has also begun, with Marder and team having recently shipped several phones to U.S. Special Forces in Okinawa to vet cellular networks.<\/p>\n\n\n\n<p>JHTV has advised Marder through the startup process which, he says, is indeed significantly time-consuming, as one might expect. To help shoulder the load, Marder and colleagues have out- sourced some of the chief financial officer-centric tasks to an outside company, and may look to bring in a fractional or full-time CEO down the road.<\/p>\n\n\n\n<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\">\n<p>\u201cJHTV has been an invaluable resource for us. We\u2019re looking forward to seeing Revelare grow and our tools potentially allowing everyone to have a secure 5G experience.\u201d \u2014Alex Marder<\/p>\n<\/blockquote>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"alignright size-medium is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"200\" height=\"300\" src=\"https:\/\/engineering.jhu.edu\/magazine\/wp-content\/uploads\/2025\/11\/JHU9557-2-200x300.jpg\" alt=\"Photo of Alex Marder, standing in front of a yellow backdrop.\" class=\"wp-image-55478\" style=\"width:400px\" srcset=\"https:\/\/engineering.jhu.edu\/magazine\/wp-content\/uploads\/2025\/11\/JHU9557-2-200x300.jpg 200w, https:\/\/engineering.jhu.edu\/magazine\/wp-content\/uploads\/2025\/11\/JHU9557-2-683x1024.jpg 683w, https:\/\/engineering.jhu.edu\/magazine\/wp-content\/uploads\/2025\/11\/JHU9557-2-768x1152.jpg 768w, https:\/\/engineering.jhu.edu\/magazine\/wp-content\/uploads\/2025\/11\/JHU9557-2-1024x1536.jpg 1024w, https:\/\/engineering.jhu.edu\/magazine\/wp-content\/uploads\/2025\/11\/JHU9557-2-1365x2048.jpg 1365w, https:\/\/engineering.jhu.edu\/magazine\/wp-content\/uploads\/2025\/11\/JHU9557-2-scaled.jpg 1707w\" sizes=\"auto, (max-width: 200px) 100vw, 200px\" \/><\/figure>\n<\/div>\n\n\n<p>Marder has also filed two patents for the underlying technology, with one of the patents going through Johns Hopkins and receiving process assistance from JHTV on how to protect as much of the intellectual property as possible. \u201cJHTV has been an invaluable resource for us,\u201d says Marder.<\/p>\n\n\n\n<p>Marder\u2019s hope is\u2014as has happened previously with technological innovations like the internet and the Global Positioning System\u2014that his team\u2019s 5G-securing technologies are proven effective in the defense sector and will eventually translate to the everyday civilian sector. \u201cWe\u2019re looking forward to seeing Revelare grow and our tools potentially allowing everyone to have a secure 5G experience,\u201d says Marder.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Faculty turn their discoveries into impactful commercial ventures.<\/p>\n","protected":false},"author":4,"featured_media":55511,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[34],"tags":[],"issue":[104],"class_list":["post-55460","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-impact","issue-fall-2025"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.9 - 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