{"id":16004,"date":"2022-01-20T08:42:56","date_gmt":"2022-01-20T13:42:56","guid":{"rendered":"https:\/\/engineering.jhu.edu\/magazine-archive\/?p=16004"},"modified":"2022-01-20T08:42:56","modified_gmt":"2022-01-20T13:42:56","slug":"personalized-treatment-for-ptsd","status":"publish","type":"post","link":"https:\/\/engineering.jhu.edu\/magazine-archive\/2022\/01\/personalized-treatment-for-ptsd\/","title":{"rendered":"Personalized Treatment for PTSD"},"content":{"rendered":"<img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-large wp-image-16013\" src=\"https:\/\/engineering.jhu.edu\/magazine-archive\/wp-content\/uploads\/2022\/01\/Option-A-1024x791.jpg\" alt=\"3D rendering of negative thoughts\" width=\"1024\" height=\"791\" srcset=\"https:\/\/engineering.jhu.edu\/magazine-archive\/wp-content\/uploads\/2022\/01\/Option-A-1024x791.jpg 1024w, https:\/\/engineering.jhu.edu\/magazine-archive\/wp-content\/uploads\/2022\/01\/Option-A-300x232.jpg 300w, https:\/\/engineering.jhu.edu\/magazine-archive\/wp-content\/uploads\/2022\/01\/Option-A-768x593.jpg 768w, https:\/\/engineering.jhu.edu\/magazine-archive\/wp-content\/uploads\/2022\/01\/Option-A-1536x1187.jpg 1536w, https:\/\/engineering.jhu.edu\/magazine-archive\/wp-content\/uploads\/2022\/01\/Option-A.jpg 2000w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/>\n<p>During a trauma, our bodies go into a state of sympathetic response, commonly known as fight-or- flight mode. For some people with post-traumatic stress disorder, this state of hypervigilance becomes the status quo, and symptoms such as irritability and an overactive startle response feel impossible to shake.<\/p>\n<p>Blythe Karow \u201902, co-founder and CEO of Evren Technologies, has developed a medical device to treat PTSD. The Phoenix is an earbud, worn for about an hour a day, that delivers an electrical stimulation to the vagus nerve, which carries signals to the brain. The stimulation, which Karow says feels like \u201ca light tingle\u201d and adjusts based on the user\u2019s stress level, boosts the parasympathetic response to put the user in a more relaxed state.<\/p>\n<p>\u201cWe\u2019re providing personalized medicine within the Phoenix earbud,\u201d says Karow.<\/p>\n<figure id=\"attachment_16009\" class=\"wp-caption alignright\" style=\"width: 224px\"><img loading=\"lazy\" decoding=\"async\" class=\"size-medium wp-image-16009\" src=\"https:\/\/engineering.jhu.edu\/magazine-archive\/wp-content\/uploads\/2022\/01\/Blythe-Karow-214x300.jpg\" alt=\"Blythe Karow\" width=\"214\" height=\"300\" srcset=\"https:\/\/engineering.jhu.edu\/magazine-archive\/wp-content\/uploads\/2022\/01\/Blythe-Karow-214x300.jpg 214w, https:\/\/engineering.jhu.edu\/magazine-archive\/wp-content\/uploads\/2022\/01\/Blythe-Karow-731x1024.jpg 731w, https:\/\/engineering.jhu.edu\/magazine-archive\/wp-content\/uploads\/2022\/01\/Blythe-Karow-768x1076.jpg 768w, https:\/\/engineering.jhu.edu\/magazine-archive\/wp-content\/uploads\/2022\/01\/Blythe-Karow.jpg 900w\" sizes=\"auto, (max-width: 214px) 100vw, 214px\" \/><figcaption class=\"wp-caption-text\">Blythe Karow<\/figcaption><\/figure>\n<p>In a 10-person proof-of-concept study, Karow says 90% responded to the treatment, and those users saw a 21-point average reduction in the severity of their PTSD symptoms. In July, the Phoenix became part of the U.S. Food and Drug Administration\u2019s Breakthrough Devices Program, a designation for devices that provide better treatments for serious conditions and that is meant to speed up its development and review process. The device could be available to the public as early as 2023, Karow says, and reimbursement could be accelerated, depending on forthcoming rulings by the Centers for Medicare and Medicaid Services.<\/p>\n<p>The granddaughter of a research pharmacist, Karow realized at Johns Hopkins that she wasn\u2019t meant for the laboratory. In her third year, she landed a pivotal internship at Medtronic, a global medical technology firm, which sent her down the path of medical device development.<\/p>\n<p>Karow says she thrives on understanding and addressing her customers\u2019 pain points. \u201cA lot of people think, \u2018If you build it, they will come,\u2019\u201d she says. \u201cBut I\u2019m very focused on human-centered design.\u201d<\/p>\n<p>After earning her master\u2019s degree in business administration from the University of Virginia and working with and consulting for startups and major medical device companies, Karow moved home to Gainesville, Florida, in 2017. She connected with her co-founder, serial entrepreneur Weaver Gaines, and together they met University of Florida scientists who were researching the use of vagal nerve stimulation for PTSD.<\/p>\n<p>\u201cI was like, \u2018Hold up, I know PTSD,\u2019\u201d Karow says. \u201cI come from a very long tradition of military service. I know there\u2019s a great need.\u201d Soon after, those scientists joined Karow and Gaines to become Evren\u2019s co-founders.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Blythe Karow \u201902, co-founder and CEO of Evren Technologies, has developed a medical device to treat PTSD by boosting the parasympathetic response to put the user in a more relaxed state.<\/p>\n","protected":false},"author":4,"featured_media":16013,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[26],"tags":[],"class_list":["post-16004","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-alumni","issue-winter-2022"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.7 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Personalized Treatment for PTSD - JHU Engineering Magazine<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/engineering.jhu.edu\/magazine-archive\/2022\/01\/personalized-treatment-for-ptsd\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Personalized Treatment for PTSD - JHU Engineering Magazine\" \/>\n<meta property=\"og:description\" content=\"Blythe Karow \u201902, co-founder and CEO of Evren Technologies, has developed a medical device to treat PTSD by boosting the parasympathetic response to put the user in a more relaxed state.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/engineering.jhu.edu\/magazine-archive\/2022\/01\/personalized-treatment-for-ptsd\/\" \/>\n<meta property=\"og:site_name\" content=\"JHU Engineering Magazine\" \/>\n<meta property=\"article:published_time\" content=\"2022-01-20T13:42:56+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/engineering.jhu.edu\/magazine-archive\/wp-content\/uploads\/2022\/01\/Option-A-1024x791.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1024\" \/>\n\t<meta property=\"og:image:height\" content=\"791\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Abby Lattes\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Abby Lattes\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"3 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"NewsArticle\",\"@id\":\"https:\\\/\\\/engineering.jhu.edu\\\/magazine-archive\\\/2022\\\/01\\\/personalized-treatment-for-ptsd\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/engineering.jhu.edu\\\/magazine-archive\\\/2022\\\/01\\\/personalized-treatment-for-ptsd\\\/\"},\"author\":{\"name\":\"Abby Lattes\",\"@id\":\"https:\\\/\\\/engineering.jhu.edu\\\/magazine-archive\\\/#\\\/schema\\\/person\\\/0244393be370fbc3ead8ec26062e9742\"},\"headline\":\"Personalized Treatment for PTSD\",\"datePublished\":\"2022-01-20T13:42:56+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/engineering.jhu.edu\\\/magazine-archive\\\/2022\\\/01\\\/personalized-treatment-for-ptsd\\\/\"},\"wordCount\":423,\"commentCount\":0,\"image\":{\"@id\":\"https:\\\/\\\/engineering.jhu.edu\\\/magazine-archive\\\/2022\\\/01\\\/personalized-treatment-for-ptsd\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/engineering.jhu.edu\\\/magazine-archive\\\/wp-content\\\/uploads\\\/2022\\\/01\\\/Option-A.jpg\",\"articleSection\":[\"Alumni\"],\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\\\/\\\/engineering.jhu.edu\\\/magazine-archive\\\/2022\\\/01\\\/personalized-treatment-for-ptsd\\\/#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/engineering.jhu.edu\\\/magazine-archive\\\/2022\\\/01\\\/personalized-treatment-for-ptsd\\\/\",\"url\":\"https:\\\/\\\/engineering.jhu.edu\\\/magazine-archive\\\/2022\\\/01\\\/personalized-treatment-for-ptsd\\\/\",\"name\":\"Personalized Treatment for PTSD - JHU Engineering Magazine\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/engineering.jhu.edu\\\/magazine-archive\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/engineering.jhu.edu\\\/magazine-archive\\\/2022\\\/01\\\/personalized-treatment-for-ptsd\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/engineering.jhu.edu\\\/magazine-archive\\\/2022\\\/01\\\/personalized-treatment-for-ptsd\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/engineering.jhu.edu\\\/magazine-archive\\\/wp-content\\\/uploads\\\/2022\\\/01\\\/Option-A.jpg\",\"datePublished\":\"2022-01-20T13:42:56+00:00\",\"author\":{\"@id\":\"https:\\\/\\\/engineering.jhu.edu\\\/magazine-archive\\\/#\\\/schema\\\/person\\\/0244393be370fbc3ead8ec26062e9742\"},\"breadcrumb\":{\"@id\":\"https:\\\/\\\/engineering.jhu.edu\\\/magazine-archive\\\/2022\\\/01\\\/personalized-treatment-for-ptsd\\\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/engineering.jhu.edu\\\/magazine-archive\\\/2022\\\/01\\\/personalized-treatment-for-ptsd\\\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/engineering.jhu.edu\\\/magazine-archive\\\/2022\\\/01\\\/personalized-treatment-for-ptsd\\\/#primaryimage\",\"url\":\"https:\\\/\\\/engineering.jhu.edu\\\/magazine-archive\\\/wp-content\\\/uploads\\\/2022\\\/01\\\/Option-A.jpg\",\"contentUrl\":\"https:\\\/\\\/engineering.jhu.edu\\\/magazine-archive\\\/wp-content\\\/uploads\\\/2022\\\/01\\\/Option-A.jpg\",\"width\":2000,\"height\":1545,\"caption\":\"3D rendering of negative thoughts\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/engineering.jhu.edu\\\/magazine-archive\\\/2022\\\/01\\\/personalized-treatment-for-ptsd\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/engineering.jhu.edu\\\/magazine-archive\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Personalized Treatment for PTSD\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/engineering.jhu.edu\\\/magazine-archive\\\/#website\",\"url\":\"https:\\\/\\\/engineering.jhu.edu\\\/magazine-archive\\\/\",\"name\":\"JHU Engineering Magazine\",\"description\":\"\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/engineering.jhu.edu\\\/magazine-archive\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Person\",\"@id\":\"https:\\\/\\\/engineering.jhu.edu\\\/magazine-archive\\\/#\\\/schema\\\/person\\\/0244393be370fbc3ead8ec26062e9742\",\"name\":\"Abby Lattes\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/c56cb7af5427f847aa288542444ba9ff3d2107bf85dc6c6d44a4d1315608258d?s=96&r=g\",\"url\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/c56cb7af5427f847aa288542444ba9ff3d2107bf85dc6c6d44a4d1315608258d?s=96&r=g\",\"contentUrl\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/c56cb7af5427f847aa288542444ba9ff3d2107bf85dc6c6d44a4d1315608258d?s=96&r=g\",\"caption\":\"Abby Lattes\"}}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Personalized Treatment for PTSD - JHU Engineering Magazine","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/engineering.jhu.edu\/magazine-archive\/2022\/01\/personalized-treatment-for-ptsd\/","og_locale":"en_US","og_type":"article","og_title":"Personalized Treatment for PTSD - JHU Engineering Magazine","og_description":"Blythe Karow \u201902, co-founder and CEO of Evren Technologies, has developed a medical device to treat PTSD by boosting the parasympathetic response to put the user in a more relaxed state.","og_url":"https:\/\/engineering.jhu.edu\/magazine-archive\/2022\/01\/personalized-treatment-for-ptsd\/","og_site_name":"JHU Engineering Magazine","article_published_time":"2022-01-20T13:42:56+00:00","og_image":[{"width":1024,"height":791,"url":"https:\/\/engineering.jhu.edu\/magazine-archive\/wp-content\/uploads\/2022\/01\/Option-A-1024x791.jpg","type":"image\/jpeg"}],"author":"Abby Lattes","twitter_card":"summary_large_image","twitter_misc":{"Written by":"Abby Lattes","Est. reading time":"3 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"NewsArticle","@id":"https:\/\/engineering.jhu.edu\/magazine-archive\/2022\/01\/personalized-treatment-for-ptsd\/#article","isPartOf":{"@id":"https:\/\/engineering.jhu.edu\/magazine-archive\/2022\/01\/personalized-treatment-for-ptsd\/"},"author":{"name":"Abby Lattes","@id":"https:\/\/engineering.jhu.edu\/magazine-archive\/#\/schema\/person\/0244393be370fbc3ead8ec26062e9742"},"headline":"Personalized Treatment for PTSD","datePublished":"2022-01-20T13:42:56+00:00","mainEntityOfPage":{"@id":"https:\/\/engineering.jhu.edu\/magazine-archive\/2022\/01\/personalized-treatment-for-ptsd\/"},"wordCount":423,"commentCount":0,"image":{"@id":"https:\/\/engineering.jhu.edu\/magazine-archive\/2022\/01\/personalized-treatment-for-ptsd\/#primaryimage"},"thumbnailUrl":"https:\/\/engineering.jhu.edu\/magazine-archive\/wp-content\/uploads\/2022\/01\/Option-A.jpg","articleSection":["Alumni"],"inLanguage":"en-US","potentialAction":[{"@type":"CommentAction","name":"Comment","target":["https:\/\/engineering.jhu.edu\/magazine-archive\/2022\/01\/personalized-treatment-for-ptsd\/#respond"]}]},{"@type":"WebPage","@id":"https:\/\/engineering.jhu.edu\/magazine-archive\/2022\/01\/personalized-treatment-for-ptsd\/","url":"https:\/\/engineering.jhu.edu\/magazine-archive\/2022\/01\/personalized-treatment-for-ptsd\/","name":"Personalized Treatment for PTSD - JHU Engineering Magazine","isPartOf":{"@id":"https:\/\/engineering.jhu.edu\/magazine-archive\/#website"},"primaryImageOfPage":{"@id":"https:\/\/engineering.jhu.edu\/magazine-archive\/2022\/01\/personalized-treatment-for-ptsd\/#primaryimage"},"image":{"@id":"https:\/\/engineering.jhu.edu\/magazine-archive\/2022\/01\/personalized-treatment-for-ptsd\/#primaryimage"},"thumbnailUrl":"https:\/\/engineering.jhu.edu\/magazine-archive\/wp-content\/uploads\/2022\/01\/Option-A.jpg","datePublished":"2022-01-20T13:42:56+00:00","author":{"@id":"https:\/\/engineering.jhu.edu\/magazine-archive\/#\/schema\/person\/0244393be370fbc3ead8ec26062e9742"},"breadcrumb":{"@id":"https:\/\/engineering.jhu.edu\/magazine-archive\/2022\/01\/personalized-treatment-for-ptsd\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/engineering.jhu.edu\/magazine-archive\/2022\/01\/personalized-treatment-for-ptsd\/"]}]},{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/engineering.jhu.edu\/magazine-archive\/2022\/01\/personalized-treatment-for-ptsd\/#primaryimage","url":"https:\/\/engineering.jhu.edu\/magazine-archive\/wp-content\/uploads\/2022\/01\/Option-A.jpg","contentUrl":"https:\/\/engineering.jhu.edu\/magazine-archive\/wp-content\/uploads\/2022\/01\/Option-A.jpg","width":2000,"height":1545,"caption":"3D rendering of negative thoughts"},{"@type":"BreadcrumbList","@id":"https:\/\/engineering.jhu.edu\/magazine-archive\/2022\/01\/personalized-treatment-for-ptsd\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/engineering.jhu.edu\/magazine-archive\/"},{"@type":"ListItem","position":2,"name":"Personalized Treatment for PTSD"}]},{"@type":"WebSite","@id":"https:\/\/engineering.jhu.edu\/magazine-archive\/#website","url":"https:\/\/engineering.jhu.edu\/magazine-archive\/","name":"JHU Engineering Magazine","description":"","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/engineering.jhu.edu\/magazine-archive\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Person","@id":"https:\/\/engineering.jhu.edu\/magazine-archive\/#\/schema\/person\/0244393be370fbc3ead8ec26062e9742","name":"Abby Lattes","image":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/secure.gravatar.com\/avatar\/c56cb7af5427f847aa288542444ba9ff3d2107bf85dc6c6d44a4d1315608258d?s=96&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/c56cb7af5427f847aa288542444ba9ff3d2107bf85dc6c6d44a4d1315608258d?s=96&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/c56cb7af5427f847aa288542444ba9ff3d2107bf85dc6c6d44a4d1315608258d?s=96&r=g","caption":"Abby Lattes"}}]}},"_links":{"self":[{"href":"https:\/\/engineering.jhu.edu\/magazine-archive\/wp-json\/wp\/v2\/posts\/16004","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/engineering.jhu.edu\/magazine-archive\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/engineering.jhu.edu\/magazine-archive\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/engineering.jhu.edu\/magazine-archive\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/engineering.jhu.edu\/magazine-archive\/wp-json\/wp\/v2\/comments?post=16004"}],"version-history":[{"count":1,"href":"https:\/\/engineering.jhu.edu\/magazine-archive\/wp-json\/wp\/v2\/posts\/16004\/revisions"}],"predecessor-version":[{"id":16014,"href":"https:\/\/engineering.jhu.edu\/magazine-archive\/wp-json\/wp\/v2\/posts\/16004\/revisions\/16014"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/engineering.jhu.edu\/magazine-archive\/wp-json\/wp\/v2\/media\/16013"}],"wp:attachment":[{"href":"https:\/\/engineering.jhu.edu\/magazine-archive\/wp-json\/wp\/v2\/media?parent=16004"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/engineering.jhu.edu\/magazine-archive\/wp-json\/wp\/v2\/categories?post=16004"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/engineering.jhu.edu\/magazine-archive\/wp-json\/wp\/v2\/tags?post=16004"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}