{"id":10577,"date":"2017-12-01T07:47:26","date_gmt":"2017-12-01T12:47:26","guid":{"rendered":"https:\/\/engineering.jhu.edu\/magazine-archive\/?p=10577"},"modified":"2017-11-30T12:46:10","modified_gmt":"2017-11-30T17:46:10","slug":"charting-the-connectome","status":"publish","type":"post","link":"https:\/\/engineering.jhu.edu\/magazine-archive\/2017\/12\/charting-the-connectome\/","title":{"rendered":"Charting the Connectome"},"content":{"rendered":"<figure id=\"attachment_10581\" class=\"wp-caption aligncenter\" style=\"width: 890px\"><a href=\"https:\/\/engineering.jhu.edu\/magazine-archive\/wp-content\/uploads\/2017\/11\/Charting-Connectome.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-10581\" src=\"https:\/\/engineering.jhu.edu\/magazine-archive\/wp-content\/uploads\/2017\/11\/Charting-Connectome.jpg\" alt=\"Connectome\" width=\"880\" height=\"683\" srcset=\"https:\/\/engineering.jhu.edu\/magazine-archive\/wp-content\/uploads\/2017\/11\/Charting-Connectome.jpg 880w, https:\/\/engineering.jhu.edu\/magazine-archive\/wp-content\/uploads\/2017\/11\/Charting-Connectome-300x233.jpg 300w, https:\/\/engineering.jhu.edu\/magazine-archive\/wp-content\/uploads\/2017\/11\/Charting-Connectome-768x596.jpg 768w\" sizes=\"auto, (max-width: 880px) 100vw, 880px\" \/><\/a><figcaption class=\"wp-caption-text\">The connectome of a learning and memory center in a fruit fly brain. (Image courtesy of Eichler et. al., 2017, Nature)<\/figcaption><\/figure>\n<p>In an early step toward mapping how all animal brains work, Johns Hopkins Engineering\u2019s <a href=\"https:\/\/engineering.jhu.edu\/ams\/faculty\/carey-priebe\/\" target=\"_blank\" rel=\"noopener\">Carey E. Priebe<\/a> has joined an international team of neuroscientists to create a complete map of the learning and memory center of the fruit fly larva brain.<\/p>\n<p>The map, known as a \u201cconnectome\u201d and <a href=\"http:\/\/www.nature.com\/nature\/journal\/v548\/n7666\/full\/nature23455.html?foxtrotcallback=true\" target=\"_blank\" rel=\"noopener\">recently reported in <em>Nature<\/em><\/a>, could serve as a guide for scientists working their way up the animal kingdom and eventually charting connections among neurons in the brains of mammals. The part of the fruit fly larva brain used in the study corresponds roughly to the cerebral cortex in mammals.<\/p>\n<p>\u201cNobody\u2019s ever done a complete connectome before, other than for a roundworm brain with roughly 300 neurons,\u201d says Priebe, a professor of <a href=\"https:\/\/engineering.jhu.edu\/ams\/\" target=\"_blank\" rel=\"noopener\">applied mathematics<\/a> and statistics, who collaborated with computer scientist <a href=\"http:\/\/www.cis.jhu.edu\/~parky\/\" target=\"_blank\" rel=\"noopener\">Youngser Park<\/a> from the Whiting School\u2019s <a href=\"http:\/\/www.cis.jhu.edu\/\" target=\"_blank\" rel=\"noopener\">Center for Imaging Science<\/a>.<\/p>\n<p>The portion of the fruit fly larva brain mapped in the project includes roughly 1,600 of the 10,000 neurons contained in a larva\u2019s entire brain. The adult fruit fly brain comprises roughly 100,000 neurons, and the leap in complexity to mammals is far greater still. At the top of the chain, the human brain contains 86 billion to 100 billion neurons.<\/p>\n<p>While Priebe does not expect to see a complete synapse-level structural connectome for the human brain completed in his lifetime, he said the new work moves the effort forward. \u201cIt is a step,\u201d he says. \u201cIt\u2019s an early step, but it\u2019s a step.\u201d<\/p>\n","protected":false},"excerpt":{"rendered":"<p>In an early step toward mapping how all animal brains work, Carey E. Priebe has joined an international team of neuroscientists to create a complete map of the learning and memory center of the fruit fly larva brain.<\/p>\n","protected":false},"author":4,"featured_media":10580,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[24],"tags":[2450,2458,2454,2446,2442,2161,113],"class_list":["post-10577","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-impact","tag-fruit-fly-larva","tag-youngser-park","tag-brain","tag-connectome","tag-carey-priebe","tag-applied-mathematics-and-statistics","tag-center-for-imaging-science","issue-winter-2018"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Charting the Connectome - JHU Engineering Magazine<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/engineering.jhu.edu\/magazine-archive\/2017\/12\/charting-the-connectome\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Charting the Connectome - JHU Engineering Magazine\" \/>\n<meta property=\"og:description\" content=\"In an early step toward mapping how all animal brains work, Carey E. 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