Wirtz, Denis

Professor
Chemical And Biomolecular Engineering
http://web1.johnshopkins.edu/wirtzlab/

Garland 265
(410) 516-8094
wirtz@jhu.edu

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News

Johns Hopkins scholars, leaders celebrate faculty research awards

September 4, 2015

Scholars from across Johns Hopkins University’s 10 divisions gathered last night at the George Peabody Library to celebrate 60 innovative research projects that are being supported by the inaugural Catalyst and Discovery awards. Thirty-seven early career scholars (five of them from WSE) received Catalyst Awards and 23 cross-divisional faculty teams, which included 14 WSE faculty […]

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About

Education
  • Ph.D. 1993, STANFORD UNIVERSITY
Experience
  • 2014 - Present:  Chairman, Internal Audit Committee, Risk Assessment Committee
  • 2014 - Present:  Other, University Research Administrations
  • 2014 - Present:  Chairman, High Performance Research Computing Facility, Big Data Group, Institutional Compliance Oversight Committee
  • 2014 - Present:  Chairman, Jhpiego Board of Directors, Gestar exectuive board, Commercial advisory group
  • 2014 - Present:  Chairman, Innovation Policy Committee, Lab Safety Committee, Hopkins Academic Council, Tenure Review Committee
  • 2014 - Present:  Chairman, Practice Center for American Cities
  • 2014 - Present:  Chairman, Research Oversight Committee, Animal Use and Care Committee, Neuroscience Task Force,
  • 2014 - Present:  Chairman, Oversight Committee, Steering Committee
  • 2014 - Present:  Chairman, SRO, Ivy Plus, AAU, NEMB
  • 2014 - Present:  Chairman, Medical Technology Enterprise Consortium (w/ JH Military & Veterns Health Institute), DOD, URS
  • 2014 - Present:  Chairman, Medical Technology Enterprise Consortium (w/ JH Military & Veterns Health Institute), DOD, URS
  • 2014 - Present:  Chairman, Internal Review Committees, Johns Hopkins University
  • 2014 - Present:  Chairman, Microscopy, Equipment Negotiation, Divisional Negotiation
  • 2014 - Present:  Chairman, SIPC, Financial and ROI
  • 2013 - Present:  Joint, SOM Pathology
  • 2011 - Present:  Director, NCI - Postdoctoral Training Program in Nanotechnology for cancer medicine
  • 2011 - Present:  Director, NCI - CNTC Predoctoral Training Program
  • 2010 - Present:  Director, NCI Physical Sciences in Oncology Center
  • 2010 - Present:  Director, NIH-NCI R25 Predoctoral Training Program
  • 2010 - 2010:  Head, Faculty search, Dept Chemical and Biomolecular Engineering, Johns Hopkins University
  • 2009 - Present:  Director, NCI - Physical Sciences Oncology Center
  • 2008 - Present:  Director, NSF REU Program in nanotechnology for biology and medicine
  • 2008 - Present:  Director, NIH-NCI T32 Postdoctoral Training Program
  • 2008 - Present:  Joint, SOM Oncology Center
  • 2007 - Present:  Co-director, IGERT graduate training program, INBT/ChemBE
  • 2006 - Present:  Co-director, Johns Hopkins Institute for NanoBioTechnology
  • 2005 - Present:  Director, HHMI NBMed graduate training program, INBT/ChemBE
  • 2003 - 2003:  Supervisor, Department of Chemical and Biomolecular Engineering
Research Areas
  • CELL migration
  • Cell Adhesion
  • Cell Engineering
  • Cell mechanics
  • High-throughput assays
  • Nuclear mechanics
  • Single-cell assays
Awards
  • 2014:  Plenary talk, IUTAM Symposium on Mechanics of Soft Active Materials
  • 2014:  Plenary talk, annual Longrifles meeting, Johns Hopkins School of Medicine
  • 2013:  2013 Plenary talk, Institute for Neuroscience, annual conference, Coimbra, Portugal
  • 2013:  Plenary talk - International Society for Mechanical Engineers - Global Congress - Nanoengineering for Medicine and Biology - Boston
  • 2012:  Distinguished Lecturer - CNTC cancer center - University of Kentucky
  • 2011:  Section 15c/d Prize of the American Institute of Chemical Engineering (AIChE)
  • 2011:  Elected member of the Board of Directors of the Belgian American Educational Foundation (BAEF)
  • 2011:  Editorial Board Member - Scientific Reports - a Nature Publication
  • 2011:  Guest Editor of a Special Issue of Physical Biology on the Physics of Cancer
  • 2010:  Guest Editor - PNAS
  • 2010:  Elected fellow of the American Physical Society (APS)
  • 2010:  Guest Editor of a Special Issue of Physical Biology on the Physics of Cancer
  • 2009:  Theophilus H. Smoot Professorship in Engineering Science - Whiting School of Engineering - Johns Hopkins University
  • 2009:  Editorial Board Member - Physical Biology
  • 2009:  Editorial Board Member - World Journal of Biological Chemistry
  • 2009:  Editor-in-Chief - Comprehensive Biophysics - Section on Cell Biophysics - Cell Press
  • 2009:  Elected fellow of the American Association for the Advancement of Science (AAAS)
  • 2009:  Schwarz Lecture - Johns Hopkins University
  • 2008:  Editor-in-Chief - Cell Health and the Cytoskeleton
  • 2008:  Named 'Nikon Partner in Science' - Nikon Inc.
  • 2008:  Member - National Science Foundation Advisory Panel on Mechanobiology
  • 2008:  Member - National Cancer Institute Advisory Panel on Physics of Cancer
  • 2007:  Editorial Board Member - Biophysical Journal
  • 2006:  Associate Editor - Journal of Nanomedicine
  • 2006:  Member - Tumor Microenvironment Study Section - NIH
  • 2006:  Editorial Board Member - Nanomedicine: Nanotechnology - Biology and Medicine
  • 2006:  Editorial Board Member - Cell Adhesion and Migration
  • 2006:  Associate Editor - Cell Adhesion and Migration
  • 2005:  Fellow - American Institute for Medical and Biological Engineering
  • 2005:  Felllow of the American Institute for Medical and Biological Engineering
  • 2004:  Member - American Society for Microbiology
  • 2004:  Outstanding Invention of 2004 - Office of Technology Commercialization - University of Maryland - Cell sensor based pathogen detection
  • 2002:  NES/NIRT Award - National Science Foundation
  • 2000:  Member - American Society for Cell Biology
  • 2000:  Member - American Physical Society
  • 1998:  Member - Biophysical Society
  • 1996:  Career-NSF Award
  • 1995:  Member - Society of Rheology
  • 1993:  Postdoctoral Fellowship - "Human Capital and Mobility" program of the European Community
  • 1989:  Research Fellowship - Stanford University
  • 1988:  Belgian American Educational Foundation (BAEF) Fellowship
  • 1988:  Prix Claes from the Royal Academy of Science and Arts of Belgium

Publications

Journal Articles
  • Perestrelo T, Correia M, Ramalho-Santos J, Wirtz D (2018).  Metabolic and Mechanical Cues Regulating Pluripotent Stem Cell Fate.  Trends in Cell Biology.  28(12).
  • Gonzalez NP, Tao J, Rochman ND, Vig D, Chiu E, Wirtz D, Sun SX (2018).  Cell tension and mechanical regulation of cell volume.  Molecular Biology of the Cell.  29(21).
  • Jayatilaka H, Umanzor FG, Shah V, Meirson T, Russo G, Starich B, Tyle P, Lee JSH, Khatau S, Gil-Henn H, Wirtz D (2018).  Tumor cell density regulates matrix metalloproteinases for enhanced migration.  Oncotarget.  9(66).
  • Parekh A, Das S, Parida S, Das CK, Dutta D, Mallick SK, Wu PH, Kumar BNP, Bharti R, Dey G, Banerjee K, Rajput S, Bharadwaj D, Pal I, Dey Kk, Rajesh Y, Jena BC, Biswas A, Banik P, Pradhan AK, Das SK, Das AK, Dhara S, Fisher PB, Wirtz D, Mills GB, Mandal M (2018).  Multi-nucleated cells use ROS to induce breast cancer chemo-resistance in vitro and in vivo.  Oncogene.  37(33).
  • Yu Y, Suryo Rahmanto Y, Lee MH, Wu PH, Phillip JM, Huang CH, Vitolo MI, Gaillard S, Martin SS, Wirtz D, Shih IM, Wang TL (2018).  Inhibition of ovarian tumor cell invasiveness by targeting SYK in the tyrosine kinase signaling pathway.  Oncogene.  37(28).
  • Noë M, Rezaee N, Asrani K, Skaro M, Groot VP, Wu PH, Olson MT, Hong SM, Kim SJ, Weiss MJ, Wolfgang CL, Makary MA, He J, Cameron JL, Wirtz D, Roberts NJ, Offerhaus GJA, Brosens LAA, Wood LD, Hruban RH (2018).  Immunolabeling of Cleared Human Pancreata Provides Insights into Three-Dimensional Pancreatic Anatomy and Pathology.  American Journal of Pathology.  188(7).
  • Wu PH, Aroush DRB, Asnacios A, Chen WC, Dokukin ME, Doss BL, Durand-Smet P, Ekpenyong A, Guck J, Guz NV, Janmey PA, Lee JSH, Moore NM, Ott A, Poh YC, Ros R, Sander M, Sokolov I, Staunton JR, Wang N, Whyte G, Wirtz D (2018).  A comparison of methods to assess cell mechanical properties.  Nature Methods.
  • Wu PH, Gilkes DM, Wirtz D (2018).  The Biophysics of 3D Cell Migration.  Annual Review of Biophysics.  47.
  • Jayatilaka H, Giri A, Karl M, Aifuwa I, Trenton NJ, Phillip JM, Khatau S, Wirtz D (2018).  EB1 and cytoplasmic dynein mediate protrusion dynamics for efficient 3-dimensional cell migration.  FASEB Journal.  32(3).
  • He L, Tao J, Maity D, Si F, Wu Y, Wu T, Prasath V, Wirtz D, Sun SX (2018).  Role of membrane-tension gated Ca2+ flux in cell mechanosensation.  Journal of Cell Science.  131(4).
  • Harris MJ, Wirtz D, Wu PH (2018).  Dissecting cellular mechanics: Implications for aging, cancer, and immunity.  Seminars in Cell and Developmental Biology.
  • Lin YA, Kang M, Chen WC, Ou YC, Cheetham AG, Wu PH, Wirtz D, Loverde SM, Cui H (2018).  Isomeric control of the mechanical properties of supramolecular filament hydrogels.  Biomaterials Science.  6(1).
  • Koons B, Sharma P, Ye Z, Mukherjee A, Lee MH, Wirtz D, Behkam B, Nain AS (2017).  Cancer Protrusions on a Tightrope: Nanofiber Curvature Contrast Quantitates Single Protrusion Dynamics.  ACS Nano.  11(12).
  • Li Y, He L, Gonzalez NAP, Graham J, Wolgemuth C, Wirtz D, Sun SX (2017).  Going with the Flow: Water Flux and Cell Shape during Cytokinesis.  Biophysical Journal.  113(11).
  • Kim JK, Louhghalam A, Lee G, Schafer BW, Wirtz D, Kim DH (2017).  Nuclear lamin A/C harnesses the perinuclear apical actin cables to protect nuclear morphology.  Nature Communications.  8(1).
  • He L, Sneider A, Chen W, Karl M, Prasath V, Wu PH, Mattson G, Wirtz D (2017).  Mammalian cell division in 3D matrices via quantitative confocal reflection microscopy.  Journal of Visualized Experiments.  2017(129).
  • Perestrelo T, Chen W, Correia M, Le C, Pereira S, Rodrigues AS, Sousa MI, Ramalho-Santos J, Wirtz D (2017).  Pluri-IQ: Quantification of Embryonic Stem Cell Pluripotency through an Image-Based Analysis Software.  Stem Cell Reports.  9(2).
  • Wang Y, Gong J, Wirtz D, Schafer BW (2017).  Affine and non-affine deformations quantified in cytoskeletal networks through three-dimensional form-finding model.  Journal of the Mechanical Behavior of Biomedical Materials.  72.
  • Phillip JM, Wu PH, Gilkes DM, Williams W, McGovern S, Daya J, Chen J, Aifuwa I, Lee JSH, Fan R, Walston J, Wirtz D (2017).  Biophysical and biomolecular determination of cellular age in humans.  Nature Biomedical Engineering.  1(7).
  • Ju JA, Godet I, Ye IC, Byun J, Jayatilaka H, Lee SJ, Xiang L, Samanta D, Lee MH, Wu PH, Wirtz D, Semenza GL, Gilkes DM (2017).  Hypoxia Selectively Enhances Integrin α5β1receptor expression in breast cancer to promote metastasis.  Molecular Cancer Research.  15(6).
  • Jayatilaka H, Tyle P, Chen JJ, Kwak M, Ju J, Kim HJ, Lee JSH, Wu PH, Gilkes DM, Fan R, Wirtz D (2017).  Synergistic IL-6 and IL-8 paracrine signalling pathway infers a strategy to inhibit tumour cell migration.  Nature Communications.  8.
  • Ahmadzadeh H, Webster MR, Behera R, Valencia AMJ, Wirtz D, Weeraratna AT, Shenoy VB (2017).  Modeling the two-way feedback between contractility and matrix realignment reveals a nonlinear mode of cancer cell invasion.  Proceedings of the National Academy of Sciences of the United States of America.  114(9).
  • Agarwal A, Wu PH, Hughes EG, Fukaya M, Tischfield MA, Langseth AJ, Wirtz D, Bergles DE (2017).  Transient Opening of the Mitochondrial Permeability Transition Pore Induces Microdomain Calcium Transients in Astrocyte Processes.  Neuron.  93(3).
  • Stroka KM, Wong BS, Shriver M, Phillip JM, Wirtz D, Kontrogianni-Konstantopoulos A, Konstantopoulos K (2017).  Loss of giant obscurins alters breast epithelial cell mechanosensing of matrix stiffness.  Oncotarget.  8(33).
  • Shah MY, Martinez-Garcia E, Phillip JM, Chambliss AB, Popovic R, Ezponda T, Small EC, Will C, Phillip MP, Neri P, Bahlis NJ, Wirtz D, Licht JD (2016).  MMSET/WHSC1 enhances DNA damage repair leading to an increase in resistance to chemotherapeutic agents.  Oncogene.  35(45).
  • Paul CD, Hung WC, Wirtz D, Konstantopoulos K (2016).  Engineered Models of Confined Cell Migration.  Annual Review of Biomedical Engineering.  18.
  • Hung WC, Yang JR, Yankaskas CL, Wong BS, Wu PH, Pardo-Pastor C, Serra SA, Chiang MJ, Gu Z, Wirtz D, Valverde MA, Yang JT, Zhang J, Konstantopoulos K (2016).  Confinement Sensing and Signal Optimization via Piezo1/PKA and Myosin II Pathways.  Cell Reports.  15(7).
  • Sarnecki JS, Burns KH, Wood LD, Waters KM, Hruban RH, Wirtz D, Wu PH (2016).  A robust nonlinear tissue-component discrimination method for computational pathology.  Laboratory Investigation.  96(4).
  • Gu Y, Chiu SL, Liu B, Wu PH, Delannoy M, Lin DT, Wirtz D, Huganir RL (2016).  Differential vesicular sorting of AMPA and GABAA receptors.  Proceedings of the National Academy of Sciences of the United States of America.  113(7).
  • Hecht VC, Sullivan LB, Kimmerling RJ, Kim DH, Hosios AM, Stockslager MA, Stevens MM, Kang JH, Wirtz D, Vander Heiden MG, Manalis SR (2016).  Biophysical changes reduce energetic demand in growth factor-deprived lymphocytes.  Journal of Cell Biology.  212(4).
  • He L, Chen W, Wu PH, Jimenez A, Wong BS, San A, Konstantopoulos K, Wirtz D (2016).  Local 3D matrix confinement determines division axis through cell shape.  Oncotarget.  7(6).
  • Wu PH, Phillip JM, Khatau SB, Chen WC, Stirman J, Rosseel S, Tschudi K, Van Patten J, Wong M, Gupta S, Baras AS, Leek JT, Maitra A, Wirtz D (2015).  Evolution of cellular morpho-phenotypes in cancer metastasis.  Scientific Reports.  5.
  • Phillip JM, Aifuwa I, Walston J, Wirtz D (2015).  The Mechanobiology of Aging.  Annual Review of Biomedical Engineering.  17.
  • Fraley SI, Wu PH, He L, Feng Y, Krisnamurthy R, Longmore GD, Wirtz D (2015).  Three-dimensional matrix fiber alignment modulates cell migration and MT1-MMP utility by spatially and temporally directing protrusions.  Scientific Reports.  5.
  • Palmieri B, Bresler Y, Wirtz D, Grant M (2015).  Multiple scale model for cell migration in monolayers: Elastic mismatch between cells enhances motility.  Scientific Reports.  5.
  • Yoon AR, Stasinopoulos I, Kim JH, Yong HM, Kilic O, Wirtz D, Bhujwalla ZM, An SS (2015).  COX-2 dependent regulation of mechanotransduction in human breast cancer cells.  Cancer Biology and Therapy.  16(3).
  • Valencia AMJ, Wu PH, Yogurtcu ON, Rao P, DiGiacomo J, Godet I, He L, Lee MH, Gilkes D, Sun SX, Wirtz D (2015).  Collective cancer cell invasion induced by coordinated contractile stresses.  Oncotarget.  6(41).
  • Wu PH, Giri A, Wirtz D (2015).  Statistical analysis of cell migration in 3D using the anisotropic persistent random walk model.  Nature Protocols.  10(3).
  • Aifuwa I, Giri A, Longe N, Lee SH, An SS, Wirtz D (2015).  Senescent stromal cells induce cancer cell migration via inhibition of RhoA/ROCK/myosin-based cell contractility.  Oncotarget.  6(31).
  • Kim DH, Li B, Si F, Phillip JM, Wirtz D, Sun SX (2015).  Volume regulation and shape bifurcation in the cell nucleus.  Journal of Cell Science.  128(18).
  • Shea DJ, Wirtz D, Stebe KJ, Konstantopoulos K (2015).  Distinct kinetic and mechanical properties govern mucin 16- and podocalyxin-mediated tumor cell adhesion to E- and L-selectin in shear f low.  Oncotarget.  6(28).
  • Lee MH, Wu PH, Gilkes D, Aifuwa I, Wirtz D (2015).  Normal mammary epithelial cells promote carcinoma basement membrane invasion by inducing microtubule-rich protrusions.  Oncotarget.  6(32).
  • Yu Y, Gaillard S, Phillip JM, Huang TC, Pinto SM, Tessarollo NG, Zhang Z, Pandey A, Wirtz D, Ayhan A, Davidson B, Wang TL, Shih IM (2015).  Inhibition of Spleen Tyrosine Kinase Potentiates Paclitaxel-Induced Cytotoxicity in Ovarian Cancer Cells by Stabilizing Microtubules.  Cancer Cell.  28(1).
  • Kim DH, Wirtz D (2015).  Cytoskeletal tension induces the polarized architecture of the nucleus.  Biomaterials.  48.
  • He L, Wirtz D (2014).  Switching from protease-independent to protease-dependent cancer cell invasion.  Biophysical Journal.  107(11).
  • Stroka KM, Jiang H, Chen SH, Tong Z, Wirtz D, Sun SX, Konstantopoulos K (2014).  Water permeation drives tumor cell migration in confined microenvironments.  Cell.  157(3).
  • Wu PH, Giri A, Sun SX, Wirtz D (2014).  Three-dimensional cell migration does not follow a random walk.  Proceedings of the National Academy of Sciences of the United States of America.  111(11).
  • Aw Yong KM, Zeng Y, Vindivich D, Phillip JM, Wu PH, Wirtz D, Getzenberg RH (2014).  Morphological effects on expression of growth differentiation factor 15 (GDF15), a marker of metastasis.  Journal of Cellular Physiology.  229(3).
  • Gilkes DM, Xiang L, Lee SJ, Chaturvedi P, Hubbi ME, Wirtz D, Semenza GL (2014).  Hypoxia-inducible factors mediate coordinated RhoA-ROCK1 expression and signaling in breast cancer cells.  Proceedings of the National Academy of Sciences of the United States of America.  111(3).
  • Gilkes DM, Semenza GL, Wirtz D (2014).  Hypoxia and the extracellular matrix: Drivers of tumour metastasis.  Nature Reviews Cancer.  14(6).
  • Wu P, Giri A, Sun S, Wirtz D (2014).  Three-dimensional cell migration does not follow a random walk.  Proceedings of the National Academy of Sciences of the United States of America.  111(11).  3949-3954.
  • Castillo M, Ebensperger R, Wirtz D, Walczak M, Hurtado DE, Celedon A (2014).  Local mechanical response of cells to the controlled rotation of magnetic nanorods.  Journal of Biomedical Materials Research - Part B Applied Biomaterials.  102(8).
  • Stroka KM, Jiang H, Chen S, Tong Z, Wirtz D, Sun S, Konstantopoulos K (2014).  Water permeation drives tumor cell migration in confined microenvironments.  Cell.  157(3).  611-23.
  • Kim DH, Cho S, Wirtz D (2014).  Tight coupling between nucleus and cell migration through the perinuclear actin cap.  Journal of Cell Science.  127(11).
  • Stroka KM, Jiang H, Chen S, Tong Z, Wirtz D, Sun S, Konstantopoulos K (2014).  Water Permeation Drives Tumor Cell Migration in Confined Microenvironments.  Cell.  157(3).  611-623.
  • Razafsky D, Wirtz D, Hodzic D (2014).  Nuclear envelope in nuclear positioning and cell migration.  Advances in Experimental Medicine and Biology.  773.
  • Guo Q, Phillip JM, Majumdar S, Wu PH, Chen J, Calderón-Colón X, Schein O, Smith BJ, Trexler MM, Wirtz D, Elisseeff JH (2013).  Modulation of keratocyte phenotype by collagen fibril nanoarchitecture in membranes for corneal repair.  Biomaterials.  34(37).
  • Bajpai S, Feng Y, Wirtz D, Longmore GD (2013).  β-Catenin serves as a clutch between low and high intercellular E-cadherin bond strengths.  Biophysical Journal.  105(10).
  • Dobrowsky TM, Rabi SA, Nedellec R, Daniels BR, Mullins JI, Mosier DE, Siliciano RF, Wirtz D (2013).  Adhesion and fusion efficiencies of human immunodeficiency virus type 1 (HIV-1) surface proteins.  Scientific Reports.  3.
  • Giri A, Bajpai S, Trenton N, Jayatilaka H, Longmore GD, Wirtz D (2013).  The Arp2/3 complex mediates multigeneration dendritic protrusions for efficient 3-dimensional cancer cell migration.  FASEB Journal.  27(10).
  • Chau E, Galloway JF, Nelson A, Breysse PN, Wirtz D, Searson PC, Sidhaye VK (2013).  Effect of modifying quantum dot surface charge on airway epithelial cell uptake in vitro.  Nanotoxicology.  7(6).
  • Stukalin EB, Aifuwa I, Kim JS, Wirtz D, Sun SX (2013).  Age-dependent stochastic models for understanding population fluctuations in continuously cultured cells.  Journal of the Royal Society Interface.  10(85).
  • Agus DB, Alexander JF, Arap W, Ashili S, Aslan JE, Austin RH, Backman V, Bethel KJ, Bonneau R, Chen W-C, Chen-Tanyolac C, Choi NC, Curley SA, Dallas M, Damania D, Davies PCW, Decuzzi P, Dickinson L, Estevez-Salmeron L, Estrella V, Ferrari M, Fischbach C, Foo J, Fraley SI, Frantz C, Fuhrmann A, Gascard P, Gatenby RA, Geng Y, Gerecht S, Gillies RJ, Godin B, Grady WM, Greenfield A, Hemphill C, Hempstead BL, Hielscher A, Hillis WD, Holland EC, Ibrahim-Hashim A, Jacks T, Johnson RH, Joo A, Katz JE, Kelbauskas L, Kesselman C, King MR, Konstantopoulos K, Kraning-Rush CM, Kuhn P, Kung K, Kwee B, Lakins JN, Lambert G, Liao D, Licht JD, Liphardt JT, Liu L, Lloyd MC, Lyubimova A, Mallick P, Marko J, McCarty OJT, Meldrum DR, Michor F, Mumenthaler SM, Nandakumar V, O'Halloran TV, Oh S, Pasqualini R, Paszek MJ, Philips KG, Poultney CS, Rana K, Reinhart-King CA, Ros R, Semenza GL, Senechal P, Shuler ML, Srinivasan S, Staunton JR, Stypula Y, Subramanian H, Tlsty TD, Tormoen GW, Tseng Y, Van O...Wu P-H (2013).  A physical sciences network characterization of non-tumorigenic and metastatic cells.  Scientific Reports.  3.
  • Chambliss AB, Wu PH, Chen WC, Sun SX, Wirtz D (2013).  Simultaneously defining cell phenotypes, cell cycle, and chromatin modifications at single-cell resolution.  FASEB Journal.  27(7).
  • Kim DH, Chambliss AB, Wirtz D (2013).  The multi-faceted role of the actin cap in cellular mechanosensation and mechanotransduction.  Soft Matter.  9(23).
  • Gilkes DM, Chaturvedi P, Bajpai S, Wong CC, Wei H, Pitcairn S, Hubbi ME, Wirtz D, Semenza GL (2013).  Collagen prolyl hydroxylases are essential for breast cancer metastasis.  Cancer Research.  73(11).
  • Gilkes DM, Bajpai S, Wong CC, Chaturvedi P, Hubbi ME, Wirtz D, Semenza GL (2013).  Procollagen lysyl hydroxylase 2 is essential for hypoxia-induced breast cancer metastasis.  Molecular Cancer Research.  11(5).
  • Gilkes DM, Bajpai S, Chaturvedi P, Wirtz D, Semenza GL (2013).  Hypoxia-inducible f0actor 1 (HIF-1) promotes extracellular matrix remodeling under hypoxic conditions by inducing P4HA1, P4HA2, and PLOD2 expression in fibroblasts.  Journal of Biological Chemistry.  288(15).
  • Kim DH, Wirtz D (2013).  Focal adhesion size uniquely predicts cell migration.  FASEB Journal.  27(4).
  • Chen WC, Wu PH, Phillip JM, Khatau SB, Choi JM, Dallas MR, Konstantopoulos K, Sun SX, Lee JSH, Hodzic D, Wirtz D (2013).  Functional interplay between the cell cycle and cell phenotypes.  Integrative Biology (United Kingdom).  5(3).
  • Lu Y, Chen JJ, Mu L, Xue Q, Wu Y, Wu PH, Li J, Vortmeyer AO, Miller-Jensen K, Wirtz D, Fan R (2013).  High-throughput secretomic analysis of single cells to assess functional cellular heterogeneity.  Analytical Chemistry.  85(4).
  • Konstantopoulos K, Wu PH, Wirtz D (2013).  Dimensional control of cancer cell migration.  Biophysical Journal.  104(2).
  • Chambliss AB, Khatau SB, Erdenberger N, Robinson DK, Hodzic D, Longmore GD, Wirtz D (2013).  The LINC-anchored actin cap connects the extracellular milieu to the nucleus for ultrafast mechanotransduction.  Scientific Reports.  3.
  • Stukalin E, Aifuwa I, Kim J, Wirtz D, Sun S (2013).  Age-dependent stochastic models for understanding population fluctuations in continuously cultured cells..  Journal of the Royal Society, Interface / the Royal Society.  10(85).  20130325.
  • Kim D, Wirtz D (2013).  Focal adhesion size uniquely predicts cell migration.  FASEB Journal.  27(4).  1351-1361.
  • Chen W, Wu PH, Phillip JM, Khatau SB, Choi J, Dallas MR, Konstantopoulos K, Sun S, Lee JS, Hodzic D, Wirtz D (2013).  Functional interplay between the cell cycle and cell phenotypes.  Integr Biol (Camb).  5(3).  523-34.
  • Wirtz D (2013).  Interstitial friction greatly impacts membrane mechanics.  Biophysical Journal.  104(6).  1217-1218.
  • Agus DB, Alexander JF, Arap W, Ashili S, Aslan JE, Austin RH, Backman V, Bethel KJ, Bonneau R, Chen WC, Chen-Tanyolac C, Choi NC, Curley SA, Dallas M, Damania D, Davies PC, Decuzzi P, Dickinson L, Estevez-Salmeron L, Estrella V, Ferrari M, Fischbach C,... (2013).  A physical sciences network characterization of non-tumorigenic and metastatic cells..  Scientific reports.  3.  1449.
  • Gong J, Zhang D, Tseng Y, Li B, Wirtz D, Schafer BW (2013).  Form-finding model shows how cytoskeleton network stiffness is realized..  PloS one.  8(10).
  • Chen W, Wu P, Phillip JM, Khatau SB, Choi JM, Dallas MR, Konstantopoulos K, Sun S, Lee JS, Hodzic D, Wirtz D (2013).  Functional interplay between the cell cycle and cell phenotypes.  Integrative Biology.  5(3).  523-534.
  • Chambliss AB, Wu P, Chen W, Sun S, Wirtz D (2013).  Simultaneously defining cell phenotypes, cell cycle, and chromatin modifications at single-cell resolution.  Faseb Journal.  27(7).  2667-2676.
  • Chambliss A, Khatau S, Erdenberger N, Robinson D, Hodzic D, Longmore G, Wirtz D (2013).  The LINC-anchored actin cap connects the extracellular milieu to the nucleus for ultrafast mechanotransduction..  Scientific reports.  3.  1087.
  • Chau E, Galloway JF, Nelson A, Breysse PN, Wirtz D, Searson P, Sidhaye VK (2013).  Effect of modifying quantum dot surface charge on airway epithelial cell uptake in vitro.  Nanotoxicology.  7(6).  1143-1151.
  • Gong J, Zhang D, Tseng Y, Li B, Wirtz D, Schafer B (2013).  Form-finding model shows how cytoskeleton network stiffness is realized..  PloS one.  8(10).
  • Stukalin EB, Aifuwa I, Kim J, Wirtz D, Sun S (2013).  Age-dependent stochastic models for understanding population fluctuations in continuously cultured cells.  Journal of the Royal Society Interface.  10(85).
  • Konstantopoulos K, Wu P, Wirtz D (2013).  Dimensional control of cancer cell migration.  Biophysical Journal.  104(2).  279-280.
  • Yap KL, Fraley SI, Thiaville MM, Jinawath N, Nakayama K, Wang J, Wang TL, Wirtz D, Shih IM (2012).  NAC1 is an actin-binding protein that is essential for effective cytokinesis in cancer cells.  Cancer Research.  72(16).
  • Kim DH, Khatau SB, Feng Y, Walcott S, Sun SX, Longmore GD, Wirtz D (2012).  Actin cap associated focal adhesions and their distinct role in cellular mechanosensing.  Scientific Reports.  2.
  • Raman PS, Alves CS, Wirtz D, Konstantopoulos K (2012).  Distinct kinetic and molecular requirements govern CD44 binding to hyaluronan versus fibrin(ogen).  Biophysical Journal.  103(3).
  • Khatau SB, Bloom RJ, Bajpai S, Razafsky D, Zang S, Giri A, Wu PH, Marchand J, Celedon A, Hale CM, Sun SX, Hodzic D, Wirtz D (2012).  The distinct roles of the nucleus and nucleus-cytoskeleton connections in three-dimensional cell migration.  Scientific Reports.  2.
  • Lee MH, Wu PH, Staunton JR, Ros R, Longmore GD, Wirtz D (2012).  Mismatch in mechanical and adhesive properties induces pulsating cancer cell migration in epithelial monolayer.  Biophysical Journal.  102(12).
  • Dallas MR, Liu G, Chen WC, Thomas SN, Wirtz D, Huso DL, Konstantopoulos K (2012).  Divergent roles of CD44 and carcinoembryonic antigen in colon cancer metastasis.  FASEB Journal.  26(6).
  • Khatau SB, Kusuma S, Hanjaya-Putra D, Mali P, Cheng L, Lee JSH, Gerecht S, Wirtz D (2012).  The differential formation of the LINC-mediated perinuclear actin cap in pluripotent and somatic cells.  PLoS ONE.  7(5).
  • Fraley SI, Feng Y, Giri A, Longmore GD, Wirtz D (2012).  Dimensional and temporal controls of three-dimensional cell migration by zyxin and binding partners.  Nature Communications.  3.
  • Wu PH, Hale CM, Chen WC, Lee JSH, Tseng Y, Wirtz D (2012).  High-throughput ballistic injection nanorheology to measure cell mechanics.  Nature Protocols.  7(1).
  • Wirtz D (2012).  MO‐C‐BRCD‐02: Physics of Cancer Cell Migration.  Medical Physics.  39(6).
  • Khatau SB, Kusuma S, Hanjaya-Putra D, Mali P, Cheng L, Lee JS, Gerecht S, Wirtz D (2012).  The differential formation of the LINC-mediated perinuclear actin cap in pluripotent and somatic cells..  PloS one.  7(5).  e36689.
  • Dallas MR, Liu G, Chen W, Thomas SN, Wirtz D, Huso DL, Konstantopoulos K (2012).  Divergent roles of CD44 and carcinoembryonic antigen in colon cancer metastasis.  FASEB J.  26(6).  2648-56.
  • Kim D, Khatau SB, Feng Y, Walcott S, Sun S, Longmore GD, Wirtz D (2012).  Actin cap associated focal adhesions and their distinct role in cellular mechanosensing.  Scientific Reports.  2.
  • Khatau SB, Bloom RJ, Bajpai S, Razafsky D, Zang S, Giri A, Wu P, Marchand J, Celedon A, Hale CM, Sun S, Hodzic D, Wirtz D (2012).  The distinct roles of the nucleus and nucleus-cytoskeleton connections in three-dimensional cell migration.  Scientific Reports.  2.
  • Dallas M, Liu G, Chen W, Thomas S, Wirtz D, Huso D, Konstantopoulos K (2012).  Erratum: Divergent roles of CD44 and carcinoembryonic antigen in colon cancer metastasis (FASEB Journal (2012) 26 (2648-2656) DOI: 10.1096/fj.12- 203786).  FASEB Journal.  26(11).  4774.
  • Raman PS, Alves CS, Wirtz D, Konstantopoulos K (2012).  Distinct kinetic and molecular requirements govern CD44 binding to hyaluronan versus fibrin(ogen).  Biophys J.  103(3).  415-23.
  • Walcott S, Kim D, Wirtz D, Sun S (2012).  Erratum: Nucleation and decay initiation are the stiffness-sensitive phases of focal adhesion maturation. (Biophysical Journal (2011) 101 (2919-2928)).  Biophysical Journal.  102(2).  377.
  • Hale CM, Chen WC, Khatau SB, Daniels BR, Lee JSH, Wirtz D (2011).  SMRT analysis of MTOC and nuclear positioning reveals the role of EB1 and LIC1 in single-cell polarization.  Journal of Cell Science.  124(24).
  • Celedon A, Hale CM, Wirtz D (2011).  Magnetic manipulation of nanorods in the nucleus of living cells.  Biophysical Journal.  101(8).
  • Wong CCL, Gilkes DM, Zhang H, Chen J, Wei H, Chaturvedi P, Fraley SI, Wong CM, Khoo US, Ng IOL, Wirtz D, Semenza GL (2011).  Hypoxia-inducible factor 1 is a master regulator of breast cancer metastatic niche formation.  Proceedings of the National Academy of Sciences of the United States of America.  108(39).
  • Wirtz D, Konstantopoulos K, Searson PC (2011).  The physics of cancer: The role of physical interactions and mechanical forces in metastasis.  Nature Reviews Cancer.  11(7).
  • Raman PS, Alves CS, Wirtz D, Konstantopoulos K (2011).  Single-molecule binding of CD44 to fibrin versus P-selectin predicts their distinct shear-dependent interactions in cancer.  Journal of Cell Science.  124(11).
  • Wirtz D (2011).  Editor-in-Chief: Professor Denis Wirtz.  Cell Health and Cytoskeleton.  3(1).
  • Wirtz D, Konstantopoulos K, Searson P (2011).  The physics of cancer: The role of physical interactions and mechanical forces in metastasis.  Nature Reviews Cancer.  11(7).  512-522.
  • Raman PS, Alves CS, Wirtz D, Konstantopoulos K (2011).  Single-molecule binding of CD44 to fibrin versus P-selectin predicts their distinct shear-dependent interactions in cancer.  J Cell Sci.  124(Pt 11).  1903-10.
  • Kim D, Wirtz D (2011).  Recapitulating cancer cell invasion in vitro.  Proceedings of the National Academy of Sciences of the United States of America.  108(17).  6693-6694.
  • Lee JSH, Denis W (2011).  Physical oncology.  Physical Biology.  8(1).
  • Lee J, Wirtz D (2011).  Physical oncology. Preface..  Physical biology.  8(1).  010301.
  • Wirtz D, Konstantopoulos K, Searson P (2011).  The physics of cancer: The role of physical interactions and mechanical forces in metastasis.  Nature Reviews Cancer.  11(7).  512-522.
  • Cheung LSL, Raman PS, Balzer EM, Wirtz D, Konstantopoulos K (2011).  Biophysics of Selectin-Ligand interactions in inflammation and cancer.  Physical Biology.  8(1).
  • Wirtz D (2011).  Editor-in-Chief: Professor Denis Wirtz.  Cell Health and Cytoskeleton.  3(1).  1.
  • Cheung LS, Raman PS, Balzer EM, Wirtz D, Konstantopoulos K (2011).  Biophysics of selectin-ligand interactions in inflammation and cancer.  Phys Biol.  8(1).  015013.
  • Celedon A, Wirtz D, Sun S (2010).  Torsional mechanics of DNA are regulated by small-molecule intercalation.  Journal of Physical Chemistry B.  114(50).
  • Mali P, Wirtz D, Searson PC (2010).  Interplay of RhoA and motility in the programmed spreading of daughter cells postmitosis.  Biophysical Journal.  99(11).
  • Daniels BR, Hale CM, Khatau SB, Kusuma S, Dobrowsky TM, Gerecht S, Wirtz D (2010).  Differences in the microrheology of human embryonic stem cells and human induced pluripotent stem cells.  Biophysical Journal.  99(11).
  • Daniels BR, Hale CM, Khatau SB, Kusuma S, Dobrowsky TM, Gerecht S, Wirtz D (2010).  Differences in the microrheology of human embryonic stem cells and human induced pluripotent stem cells..  Biophysical journal.  99(11).  3563-70.
  • Dajkovic A, Pichoff S, Lutkenhaus J, Wirtz D (2010).  Cross-linking FtsZ polymers into coherent Z rings.  Molecular Microbiology.  78(3).
  • Stahl PJ, Romano NH, Wirtz D, Yu SM (2010).  PEG-based hydrogels with collagen mimetic peptide-mediated and tunable physical cross-links.  Biomacromolecules.  11(9).
  • Daniels BR, Dobrowsky TM, Perkins EM, Sun SX, Wirtz D (2010).  MEX-5 enrichment in the C. elegans early embryo mediated by differential diffusion.  Development.  137(15).
  • Dobrowsky TM, Daniels BR, Siliciano RF, Sun SX, Wirtz D (2010).  Organization of cellular receptors into a nanoscale junction during HIV-1 adhesion.  PLoS Computational Biology.  6(7).
  • Fraley SI, Feng Y, Krishnamurthy R, Kim DH, Celedon A, Longmore GD, Wirtz D (2010).  A distinctive role for focal adhesion proteins in three-dimensional cell motility.  Nature Cell Biology.  12(6).
  • Esue O, Rupprecht L, Sun SX, Wirtz D (2010).  Dynamics of the bacterial intermediate filament crescentin in vitroand in vivo.  PLoS ONE.  5(1).
  • Khatau SB, Kim DH, Hale CM, Bloom RJ, Wirtz D (2010).  The perinuclear actin cap in health and disease.  Nucleus.  1(4).
  • Dobrowsky T, Daniels B, Siliciano R, Sun S, Wirtz D (2010).  Organization of Cellular Receptors into a Nanoscale Junction during HIV-1 Adhesion.  Plos Computational Biology.  6(7).
  • Mali P, Wirtz D, Searson P (2010).  Interplay of RhoA and motility in the programmed spreading of daughter cells postmitosis.  Biophysical Journal.  99(11).  3526-3534.
  • DANIELS B, DOBROWSKY T, PERKINS E, SUN S, Wirtz D (2010).  MEX-5 enrichment in the C. elegans early embryo mediated by differential diffusion.  Development.  137(15).  2579-2585.
  • Wirtz D, Khatau SB (2010).  Protein filaments: Bundles from boundaries.  Nature Materials.  9(10).
  • Wirtz D, Khatau S (2010).  Protein filaments: Bundles from boundaries.  Nature Materials.  9(10).  788-790.
  • Wildt B, Wirtz D, Searson PC (2010).  Triggering cell detachment from patterned electrode arrays by programmed subcellular release.  Nature Protocols.  5(7).
  • Wildt B, Wirtz D, Searson P (2010).  Triggering cell detachment from patterned electrode arrays by programmed subcellular release.  Nature Protocols.  5(7).  1273-1280.
  • Dobrowsky T, Daniels B, Siliciano R, Sun S, Wirtz D (2010).  Organization of cellular receptors into a nanoscale junction during HIV-1 adhesion..  PLoS computational biology.  6(7).  e1000855.
  • ESUE O, RUPPRECHT L, SUN S, Wirtz D (2010).  Dynamics of the Bacterial Intermediate Filament Crescentin In Vitro and In Vivo.  PLOS ONE.  5(1).
  • Celedon A, Wirtz D, Sun S (2010).  Torsional Mechanics of DNA Are Regulated by Small-Molecule Intercalation.  Journal of Physical Chemistry B.  114(50).  16929-16935.
  • Wirtz D (2009).  Particle-tracking microrheology of living cells: Principles and applications.  Annual Review of Biophysics.  38(1).
  • Khatau SB, Hale CM, Stewart-Hutchinson PJ, Patel MS, Stewart CL, Searson PC, Hodzic D, Wirtz D (2009).  A perinuclear actin cap regulates nuclear shape.  Proceedings of the National Academy of Sciences of the United States of America.  106(45).
  • Hale CM, Sun SX, Wirtz D (2009).  Resolving the role of actoymyosin contractility in cell microrheology.  PLoS ONE.  4(9).
  • Bajpai S, Feng Y, Krishnamurthy R, Longmore GD, Wirtz D (2009).  Loss of α-catenin decreases the strength of single E-cadherin bonds between human cancer cells.  Journal of Biological Chemistry.  284(27).
  • Celedon A, Nodelman IM, Wildt B, Dewan R, Searson P, Wirtz D, Bowman GD, Sun SX (2009).  Magnetic tweezers measurement of single molecule torque.  Nano Letters.  9(4).
  • Galloway JF, Park J, Lee KH, Wirtz D, Searson PC (2009).  Exploiting nucleation and growth in the synthesis and electrical passivation of CdSe quantum dots.  Science of Advanced Materials.  1(1).
  • Lai SK, Wang YY, Wirtz D, Hanes J (2009).  Micro- and macrorheology of mucus.  Advanced Drug Delivery Reviews.  61(2).
  • Daniels BR, Perkins EM, Dobrowsky TM, Sun SX, Wirtz D (2009).  Asymmetric enrichment of PIE-1 in the Caenorhabditis elegans zygote mediated by binary counterdiffusion.  Journal of Cell Biology.  184(4).
  • Esue O, Tseng Y, Wirtz D (2009).  α-actinin and filamin cooperatively enhance the stiffness of actin filament networks.  PLoS ONE.  4(2).
  • Wildt B, Wirtz D, Searson PC (2009).  Programmed subcellular release for studying the dynamics of cell detachment.  Nature Methods.  6(3).
  • Lai SK, Wang YY, Cone R, Wirtz D, Hanes J (2009).  Altering mucus rheology to "solidify" human mucus at the nanoscale.  PLoS ONE.  4(1).
  • Lan G, Daniels BR, Dobrowsky TM, Wirtz D, Sun SX (2009).  Condensation of FtsZ filaments can drive bacterial cell division.  Proceedings of the National Academy of Sciences of the United States of America.  106(1).
  • CELEDON A, NODELMAN I, WILDT B, DEWAN R, Searson P, Wirtz D, BOWMAN G, SUN S (2009).  Magnetic Tweezers Measurement of Single Molecule Torque.  NANO LETTERS.  9(4).  1720-1725.
  • HALE C, SUN S, Wirtz D (2009).  Resolving the Role of Actoymyosin Contractility in Cell Microrheology.  PLOS ONE.  4(9).
  • DANIELS B, PERKINS E, DOBROWSKY T, SUN S, Wirtz D (2009).  Asymmetric enrichment of PIE-1 in the Caenorhabditis elegans zygote mediated by binary counterdiffusion.  JOURNAL OF CELL BIOLOGY.  184(4).  473-479.
  • Wildt B, Wirtz D, Searson P (2009).  Programmed subcellular release for studying the dynamics of cell detachment.  Nature Methods.  6(3).  211-213.
  • LAN G, DANIELS B, DOBROWSKY T, Wirtz D, SUN S (2009).  Condensation of FtsZ filaments can drive bacterial cell division.  PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA.  106(1).  121-126.
  • Wirtz D (2009).  Particle-tracking microrheology of living cells: Principles and applications.  Annual Review of Biophysics.  38(1).  301-326.
  • Khatau SB, Hale CM, Stewart-Hutchinson PJ, Patel MS, Stewart CL, Searson P, Hodzic D, Wirtz D (2009).  A perinuclear actin cap regulates nuclear shape.  Proceedings of the National Academy of Sciences of the United States of America.  106(45).  19017-19022.
  • Dobrowsky TM, Panorchan P, Konstantopoulos K, Wirtz D (2008).  Chapter 15 Live-Cell Single-Molecule Force Spectroscopy.  Methods in Cell Biology.  89.
  • Thompson MS, Wirtz D (2008).  Chapter 18 Sensing Cytoskeletal Mechanics by Ballistic Intracellular Nanorheology (BIN) Coupled with Cell Transfection.  Methods in Cell Biology.  89.
  • Esue O, Harris ES, Higgs HN, Wirtz D (2008).  The Filamentous Actin Cross-Linking/Bundling Activity of Mammalian Formins.  Journal of Molecular Biology.  384(2).
  • Hale CM, Shrestha AL, Khatau SB, Stewart-Hutchinson PJ, Hernandez L, Stewart CL, Hodzic D, Wirtz D (2008).  Dysfunctional connections between the nucleus and the actin and microtubule networks in laminopathic models.  Biophysical Journal.  95(11).
  • Lai SK, Wang YY, Hida K, Cone R, Wirtz D, Hanes J (2008).  Selective control of mucus mesh size and nanorheology for prevention of infectious diseases.  AIChE Annual Meeting, Conference Proceedings.
  • Bajpai S, Correia J, Feng Y, Figueiredo J, Sun SX, Longmore GD, Suriano G, Wirtz D (2008).  α-Catenin mediates initial E-cadherin-dependent cell- cell recognition and subsequent bond strengthening.  Proceedings of the National Academy of Sciences of the United States of America.  105(47).
  • Lan G, Dajkovic A, Wirtz D, Sun SX (2008).  Polymerization and bundling kinetics of FtsZ filaments.  Biophysical Journal.  95(8).
  • Bloom RJ, George JP, Celedon A, Sun SX, Wirtz D (2008).  Mapping local matrix remodeling induced by a migrating tumor cell using three-dimensional multiple-particle tracking.  Biophysical Journal.  95(8).
  • Dobrowsky TM, Zhou Y, Sun SX, Siliciano RF, Wirtz D (2008).  Monitoring early fusion dynamics of human immunodeficiency virus type 1 at single-molecule resolution.  Journal of Virology.  82(14).
  • Stewart-Hutchinson PJ, Hale CM, Wirtz D, Hodzic D (2008).  Structural requirements for the assembly of LINC complexes and their function in cellular mechanical stiffness.  Experimental Cell Research.  314(8).
  • Zhou X, Rowe RG, Hiraoka N, George JP, Wirtz D, Mosher DF, Virtanen I, Chernousov MA, Weiss SJ (2008).  Fibronectin fibrillogenesis regulates three-dimensional neovessel formation.  Genes and Development.  22(9).
  • Dajkovic A, Lan G, Sun SX, Wirtz D, Lutkenhaus J (2008).  MinC Spatially Controls Bacterial Cytokinesis by Antagonizing the Scaffolding Function of FtsZ.  Current Biology.  18(4).
  • DOBROWSKY T, ZHOU Y, SUN S, SILICIANO R, Wirtz D (2008).  Monitoring early fusion dynamics of human immunodeficiency virus type 1 at single-molecule resolution.  JOURNAL OF VIROLOGY.  82(14).  7022-7033.
  • LAN G, DAJKOVIC A, Wirtz D, SUN S (2008).  Polymerization and bundling kinetics of FtsZ filaments.  BIOPHYSICAL JOURNAL.  95(8).  4045-4056.
  • BAJPAI S, CORREIA J, FENG Y, FIGUEIREDO J, SUN S, LONGMORE G, SURIANO G, Wirtz D (2008).  alpha-Catenin mediates initial E-cadherin-dependent cell-cell recognition and subsequent bond strengthening.  PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA.  105(47).  18331-18336.
  • BLOOM R, GEORGE J, CELEDON A, SUN S, Wirtz D (2008).  Mapping local matrix remodeling induced by a migrating tumor cell using three-dimensional multiple-particle tracking.  BIOPHYSICAL JOURNAL.  95(8).  4077-4088.
  • DAJKOVIC A, LAN G, SUN S, Wirtz D, LUTKENHAUS J (2008).  MinC spatially controls bacterial cytokinesis by antagonizing the scaffolding function of FtsZ.  CURRENT BIOLOGY.  18(4).  235-244.
  • Dobrowsky TM, Panorchan P, Konstantopoulos K, Wirtz D (2008).  Chapter 15: Live-cell single-molecule force spectroscopy.  Methods Cell Biol.  89.  411-32.
  • Panorchan P, Lee JSH, Daniels BR, Kole TP, Tseng Y, Wirtz D (2007).  Probing Cellular Mechanical Responses to Stimuli Using Ballistic Intracellular Nanorheology.  Methods in Cell Biology.  83.
  • Xu J, Chang T, Inglett GE, Kim S, Tseng Y, Wirtz D (2007).  Micro-heterogeneity and micro-rheological properties of high-viscosity oat β-glucan solutions.  Food Chemistry.  103(4).
  • Lee JSH, Hale CM, Panorchan P, Khatau SB, George JP, Tseng Y, Stewart CL, Hodzic D, Wirtz D (2007).  Nuclear lamin A/C deficiency induces defects in cell mechanics, polarization, and migration.  Biophysical Journal.  93(7).
  • Esue O, Carson AA, Tseng Y, Wirtz D (2006).  A direct interaction between actin and vimentin filaments mediated by the tail domain of vimentin.  Journal of Biological Chemistry.  281(41).
  • Panorchan P, George JP, Wirtz D (2006).  Probing Intercellular Interactions between Vascular Endothelial Cadherin Pairs at Single-molecule Resolution and in Living Cells.  Journal of Molecular Biology.  358(3).
  • Lee JSH, Panorchan P, Hale CM, Khatau SB, Kole TP, Tseng Y, Wirtz D (2006).  Ballistic intracellular nanorheology reveals ROCK-hard cytoplasmic stiffening response to fluid flow.  Journal of Cell Science.  119(9).
  • Esue O, Wirtz D, Tseng Y (2006).  GTPase activity, structure, and mechanical properties of filaments assembled from bacterial cytoskeleton protein MreB.  Journal of Bacteriology.  188(3).
  • Panorchan P, Thompson MS, Davis KJ, Tseng Y, Konstantopoulos K, Wirtz D (2006).  Single-molecule analysis of cadherin-mediated cell-cell adhesion.  Journal of Cell Science.  119(1).
  • Panorchan P, Thompson M, Davis KJ, Tseng Y, Konstantopoulos K, Wirtz D (2006).  Single-molecule analysis of cadherin-mediated cell-cell adhesion.  J Cell Sci.  119(Pt 1).  66-74.
  • Atilgan E, Wirtz D, Sun SX (2006).  Mechanics and dynamics of actin-driven thin membrane protrusions.  Biophysical Journal.  90(1).
  • Panorchan P, Lee JSH, Kole TP, Tseng Y, Wirtz D (2006).  Microrheology and ROCK signaling of human endothelial cells embedded in a 3D matrix.  Biophysical Journal.  91(9).
  • ATILGAN E, Wirtz D, SUN S (2006).  Mechanics and dynamics of actin-driven thin membrane protrusions.  BIOPHYSICAL JOURNAL.  90(1).  65-76.
  • Sun SX, Wirtz D (2006).  Mechanics of enveloped virus entry into host cells.  Biophysical Journal.  90(1).
  • SUN S, Wirtz D (2006).  Mechanics of enveloped virus entry into host cells.  BIOPHYSICAL JOURNAL.  90(1).  L10-L12.
  • Daniels BR, Masi BC, Wirtz D (2006).  Probing single-cell micromechanics in vivo: The microrheology of C. elegans developing embryos.  Biophysical Journal.  90(12).
  • Chang MI, Panorchan P, Dobrowsky TM, Tseng Y, Wirtz D (2005).  Single-molecule analysis of human immunodeficiency virus type 1 gp120-receptor interactions in living cells.  Journal of Virology.  79(23).
  • Wirtz D (2005).  Live-cell microrheology.  AIChE Annual Meeting, Conference Proceedings.
  • Tseng Y, Kole TP, Lee JSH, Fedorov E, Almo SC, Schafer BW, Wirtz D (2005).  How actin crosslinking and bundling proteins cooperate to generate an enhanced cell mechanical response.  Biochemical and Biophysical Research Communications.  334(1).
  • Esue O, Tseng Y, Wirtz D (2005).  The rapid onset of elasticity during the assembly of the bacterial cell-division protein FtsZ.  Biochemical and Biophysical Research Communications.  333(2).
  • Esue O, Tseng Y, Wirtz D (2005).  Mechanical shear can accelerate the gelation of actin filament networks.  Physical Review Letters.  95(4).
  • Gupton SL, Anderson KL, Kole TP, Fischer RS, Ponti A, Hitchcock-DeGregori SE, Danuser G, Fowler VM, Wirtz D, Hanein D, Waterman-Storer CM (2005).  Cell migration without a lamellipodium: Translation of actin dynamics into cell movement mediated by tropomyosin.  Journal of Cell Biology.  168(4).
  • Lee JSH, Chang MI, Tseng Y, Wirtz D (2005).  Cdc42 mediates nucleus movement and MTOC polarization in Swiss 3T3 fibroblasts under mechanical shear stress.  Molecular Biology of the Cell.  16(2).
  • Esue O, Cordero M, Wirtz D, Tseng Y (2005).  The assembly of MreB, a prokaryotic homolog of actin.  Journal of Biological Chemistry.  280(4).
  • Atilgan E, Wirtz D, Sun S (2005).  Morphology of the lamellipodium and organization of actin filaments at the leading edge of crawling cells.  Biophysical Journal.  89(5).  3589-3602.
  • Kole T, Tseng Y, Jiang I, Katz J, Wirtz D (2005).  Intracellular mechanics of migrating fibroblasts.  Molecular Biology of the Cell.  16(1).  328-338.
  • Esue O, Tseng Y, Wirtz D (2005).  The rapid onset of elasticity during the assembly of the bacterial cell-division protein FtsZ.  Biochemical and Biophysical Research Communications.  333(2).  508-516.
  • Kole TP, Tseng Y, Jiang I, Katz JL, Wirtz D (2005).  Intracellular mechanics of migrating fibroblasts.  Molecular Biology of the Cell.  16(1).
  • Tseng Y, Kole T, Lee J, Fedorov E, Almo S, Schafer B, Wirtz D (2005).  How actin crosslinking and bundling proteins cooperate to generate an enhanced cell mechanical response.  Biochemical and Biophysical Research Communications.  334(1).  183-192.
  • Atilgan E, Wirtz D, Sun SX (2005).  Morphology of the lamellipodium and organization of actin filaments at the leading edge of crawling cells.  Biophysical Journal.  89(5).
  • ATILGAN E, Wirtz D, SUN S (2005).  Morphology of the lamellipodium and organization of actin filaments at the leading edge of crawling cells.  BIOPHYSICAL JOURNAL.  89(5).  3589-3602.
  • Tseng Y, Wirtz D (2004).  Dendritic branching and homogenization of actin networks mediated by Arp2/3 complex.  Physical Review Letters.  93(25).
  • Dawson M, Wirtz D, Hanes J (2004).  Gene carriers modified with PEG demonstrate increased transport and stability in mucus as explored with high-resolution nanoparticle tracking.  AIChE Annual Meeting, Conference Proceedings.
  • Dawson M, Wirtz D, Hanes J (2004).  Microscopic viscoelasticity of CF sputum determined by high-resolution nanoparticle tracking.  AIChE Annual Meeting, Conference Proceedings.
  • Kole TP, Tseng Y, Wirtz D (2004).  Intracellular microrheology as a tool for the measurement of the local mechanical properties of live cells.  Methods in Cell Biology.  2004(78).
  • Panorchan P, Schafer BW, Wirtz D, Tseng Y (2004).  Nuclear envelope breakdown requires overcoming the mechanical integrity of the nuclear lamina.  Journal of Biological Chemistry.  279(42).
  • Kole TP, Tseng Y, Huang L, Katz JL, Wirtz D (2004).  Rho kinase regulates the intracellular micromechanical response of adherent cells to Rho activation.  Molecular Biology of the Cell.  15(7).
  • Klein MG, Shi W, Ramagopal U, Tseng Y, Wirtz D, Kovar DR, Staiger CJ, Almo SC (2004).  Structure of the actin crosslinking core of fimbrin.  Structure.  12(6).
  • Hanley WD, Wirtz D, Konstantopoulos K (2004).  Distinct kinetic and mechanical properties govern selectin-leukocyte interactions.  Journal of Cell Science.  117(12).
  • Dawson M, Krauland E, Wirtz D, Hanes J (2004).  Transport of polymeric nanoparticle gene carriers in gastric mucus.  Biotechnology Progress.  20(3).
  • Tseng Y, Lee JSH, Kole TP, Jiang I, Wirtz D (2004).  Micro-organization and visco-elasticity of the interphase nucleus revealed by particle nanotracking.  Journal of Cell Science.  117(10).
  • Heidemann SR, Wirtz D (2004).  Towards a regional approach to cell mechanics.  Trends in Cell Biology.  14(4).
  • Suh J, Wirtz D, Hanes J (2004).  Real-time intracellular transport of gene nanocarriers studied by multiple particle tracking.  Biotechnology Progress.  20(2).
  • Tseng Y, An KM, Esue O, Wirtz D (2004).  The Bimodal Role of Filamin in Controlling the Architecture and Mechanics of F-actin Networks.  Journal of Biological Chemistry.  279(3).
  • Panorchan P, Schafer B, Wirtz D, Tseng Y (2004).  Nuclear envelope breakdown requires overcoming the mechanical integrity of the nuclear lamina.  Journal of Biological Chemistry.  279(42).  43462-43467.
  • Panorchan P, Wirtz D, Tseng Y (2004).  Structure-function relationship of biological gels revealed by multiple-particle tracking and differential interference contrast microscopy: The case of human lamin networks.  Physical Review E - Statistical Physics, Plasmas, Fluids, and Related Interdisciplinary Topics.  70(4).
  • Hanley WD, Wirtz D, Konstantopoulos K (2004).  Distinct kinetic and mechanical properties govern selectin-leukocyte interactions.  J Cell Sci.  117(Pt 12).  2503-11.
  • Dawson M, Wirtz D, Hanes J (2003).  Enhanced Viscoelasticity of Human Cystic Fibrotic Sputum Correlates with Increasing Microheterogeneity in Particle Transport.  Journal of Biological Chemistry.  278(50).
  • Yamada S, Wirtz D, Coulombe PA (2003).  The mechanical properties of simple epithelial keratins 8 and 18: Discriminating between interfacial and bulk elasticities.  Journal of Structural Biology.  143(1).
  • Zhou Y, Wirtz D, Chirikjian GS (2003).  Determining the Gaussian probability distribution of the best-fit ellipsoid of revolution for a polymer chain from planar projections.  Inverse Problems.  19(3).
  • Suh J, Wirtz D, Hanes J (2003).  Efficient active transport of gene nanocarriers to the cell nucleus.  Proceedings of the National Academy of Sciences of the United States of America.  100(7).
  • Hanley W, McCarty O, Jadhav S, Tseng Y, Wirtz D, Konstantopoulos K (2003).  Single molecule characterization of P-selectin/ligand binding.  Journal of Biological Chemistry.  278(12).
  • Li HY, Wirtz D, Zheng Y (2003).  A mechanism of coupling RCC1 mobility to RanGTP production on the chromatin in vivo.  Journal of Cell Biology.  160(5).
  • Konstantopoulos K, Hanley W, Wirtz D (2003).  Receptor-ligand binding: 'Catch' bonds finally caught.  Current Biology.  13(15).  R611-R613.
  • Hanley W, McCarty O, Jadhav S, Tseng Y, Wirtz D, Konstantopoulos K (2003).  Single molecule characterization of P-selectin/ligand binding.  J Biol Chem.  278(12).  10556-61.
  • Suh J, Wirtz D, Hanes J (2002).  Real-time quantitation of intracellular polycation/DNA nanocomplex transport: Evidence for directed motion.  Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings.  1.
  • Tseng Y, Kole TP, Wirtz D (2002).  Micromechanical mapping of live cells by multiple-particle-tracking microrheology.  Biophysical Journal.  83(6).
  • Rahman A, Tseng Y, Wirtz D (2002).  Micromechanical coupling between cell surface receptors and RGD peptides.  Biochemical and Biophysical Research Communications.  296(3).
  • Tseng Y, Kole TP, Lee SHJ, Wirtz D (2002).  Local dynamics and viscoelastic properties of cell biological systems.  Current Opinion in Colloid and Interface Science.  7(3-4).
  • Tseng Y, Schafer BW, Almo SC, Wirtz D (2002).  Functional synergy of actin filament cross-linking proteins.  Journal of Biological Chemistry.  277(28).
  • Tseng Y, An KM, Wirtz D (2002).  Microheterogeneity controls the rate of gelation of actin filament networks.  Journal of Biological Chemistry.  277(20).
  • Xu J, Tseng Y, Carriere CJ, Wirtz D (2002).  Microheterogeneity and microrheology of wheat gliadin suspensions studied by multiple-particle tracking.  Biomacromolecules.  3(1).
  • Yamada S, Wirtz D, Coulombe PA (2002).  Pairwise assembly determines the intrinsic potential for self-organization and mechanical properties of keratin filaments.  Molecular Biology of the Cell.  13(1).
  • Yamada S, Wirtz D, Coulombe P (2002).  Pairwise assembly determines the intrinsic potential for self-organization and mechanical properties of keratin filaments.  Molecular Biology of the Cell.  13(1).  382-391.
  • Tseng Y, Schafer B, Almo S, Wirtz D (2002).  Functional synergy of actin filament cross-linking proteins.  Journal of Biological Chemistry.  277(28).  25609-25616.
  • Goodman A, Tseng Y, Wirtz D (2002).  Effect of length, topology, and concentration on the microviscosity and microheterogeneity of DNA solutions.  Journal of Molecular Biology.  323(2).
  • Wirtz D (2001).  Regulation of cell-matrix adhesion strength by cytoskeleton re-organization.  American Society of Mechanical Engineers, Bioengineering Division (Publication) BED.  50.
  • Bousquet O, Linglei M, Yamada S, Gu C, Idei T, Takahashi K, Wirtz D, Coulombe PA (2001).  The nonhelical tail domain of keratin 14 promotes filament bundling and enhances the mechanical properties of keratin intermediate filaments in vitro.  Journal of Cell Biology.  155(5).
  • Tseng Y, Fedorov E, McCaffery JM, Almo SC, Wirtz D (2001).  Micromechanics and ultrastructure of actin filament networks crosslinked by human fascin: A comparison with α-actinin.  Journal of Molecular Biology.  310(2).
  • Ma L, Yamada S, Wirtz D, Coulombe PA (2001).  A 'hot-spot' mutation alters the mechanical properties of keratin filament networks.  Nature Cell Biology.  3(5).
  • Tseng Y, Wirtz D (2001).  Mechanics and multiple-particle tracking microheterogeneity of α-actinin-cross-linked actin filament networks.  Biophysical Journal.  81(3).
  • Xu J, Bietz JA, Felker FC, Carriere CJ, Wirtz D (2001).  Rheological properties of vital wheat gluten suspensions.  Cereal Chemistry.  78(2).
  • Xu J, Bietz J, Felker F, Carriere C, Wirtz D (2001).  Rheological properties of vital wheat gluten suspensions.  Cereal Chemistry.  78(2).  181-185.
  • Xu J, Tseng Y, Wirtz D (2000).  Strain hardening of actin filament networks: Regulation by the dynamic cross-linking protein α-actinin.  Journal of Biological Chemistry.  275(46).
  • Coulombe PA, Bousquet O, Ma L, Yamada S, Wirtz D (2000).  The 'ins' and 'outs' of intermediate filament organization.  Trends in Cell Biology.  10(10).
  • Haber C, Ruiz SA, Wirtz D (2000).  Shape anisotropy of a single random-walk polymer.  Proceedings of the National Academy of Sciences of the United States of America.  97(20).
  • Xu J, Tseng Y, Wirtz D (2000).  Strain hardening of actin filament networks: Regulation by the dynamic cross-linking protein α-actinin.  Journal of Biological Chemistry.  275(46).  35886-35892.
  • Coulombe P, Bousquet O, Ma L, Yamada S, Wirtz D (2000).  The 'ins' and 'outs' of intermediate filament organization.  Trends in Cell Biology.  10(10).  420-428.
  • Haber C, Wirtz D (2000).  Magnetic tweezers for DNA micromanipulation.  Review of Scientific Instruments.  71(12).
  • Yamada S, Wirtz D, Kuo SC (2000).  Mechanics of living cells measured by laser tracking microrheology.  Biophysical Journal.  78(4).
  • Apgar J, Tseng Y, Fedorov E, Herwig MB, Almo SC, Wirtz D (2000).  Multiple-particle tracking measurements of heterogeneities in solutions of actin filaments and actin bundles.  Biophysical Journal.  79(2).
  • Haber C, Wirtz D (2000).  Shear-induced assembly of λ-phage DNA.  Biophysical Journal.  79(3).
  • LeDuc P, Pfister B, Xu Y, Wirtz D, Bao G (1999).  In situ dynamics of concentrated DNA molecules in a shear flow.  American Society of Mechanical Engineers, Bioengineering Division (Publication) BED.  43.
  • LeDuc P, Tsourkas A, Wirtz D, Bao G (1999).  Dynamics of individual deoxyribonucleic acid molecules visualized in situ with shear strain.  Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings.  2.
  • Wirtz D, Evans E (1999).  Materials science of the cell.  MRS Bulletin.  24(10).
  • LeDuc P, Tsourkas A, Lavan D, Wirtz D, Bao G (1999).  Visualization of the real-time dynamics of individual deoxyribonucleic acid molecules under shear strain.  American Society of Mechanical Engineers, Bioengineering Division (Publication) BED.  42.
  • Ma L, Xu J, Coulombe PA, Wirtz D (1999).  Keratin filament suspensions show unique micromechanical properties.  Journal of Biological Chemistry.  274(27).
  • LeDuc P, Haber C, Bao G, Wirtz D (1999).  Dynamics of individual flexible polymers in a shear flow.  Nature.  399(6736).
  • Rufener K, Palmer A, Xu J, Wirtz D (1999).  High-frequency dynamics and microrheology of macromolecular solutions probed by diffusing wave spectroscopy: the case of concentrated solutions of F-actin.  Journal of Non-Newtonian Fluid Mechanics.  82(2-3).
  • Palmer A, Rufener K, Wirtz D, Xu J (1999).  High-frequency dynamics and microrheology of macromolecular solutions probed by diffusing wave spectroscopy: the case of concentrated solutions of F-actin.  Journal of Non-Newtonian Fluid Mechanics.  82(2-3).  303-314.
  • Palmer A, Mason TG, Xu J, Kuo SC, Wirtz D (1999).  Diffusing wave spectroscopy microrheology of actin filament networks.  Biophysical Journal.  76(2).
  • Kuo S, Palmer A, Wirtz D, Xu J (1999).  Erratum: Diffusing wave spectroscopy microrheology of actin filament networks (Biophysical Journal (1999) 76 (1063-1071)).  Biophysical Journal.  76(4).  2317.
  • Evans E, Wirtz D (1999).  Materials science of the cell.  MRS Bulletin.  24(10).  19-20.
  • Xu J, Viasnoff V, Wirtz D (1998).  Compliance of actin filament networks measured by particle-tracking microrheology and diffusing wave spectroscopy.  Rheologica Acta.  37(4).
  • Xu J, Palmer A, Wirtz D (1998).  Rheology and microrheology of semiflexible polymer solutions: Actin filament networks.  Macromolecules.  31(19).
  • Petka WA, Harden JL, McGrath KP, Wirtz D, Tirrell DA (1998).  Reversible hydrogels from self-assembling artificial proteins.  Science.  281(5375).
  • Mason TG, Dhople A, Wirtz D (1998).  Linear viscoelastic moduli of concentrated DNA solutions.  Macromolecules.  31(11).
  • Xu J, Wirtz D, Pollard TD (1998).  Dynamic cross-linking by α-actinin determines the mechanical properties of actin filament networks.  Journal of Biological Chemistry.  273(16).
  • Silva AS, Wirtz D (1998).  Dominant diffusing mode in the self-similar phase separation of a magnetic suspension in a magnetic field.  Langmuir.  14(3).
  • Silva A, Wirtz D (1998).  Dominant diffusing mode in the self-similar phase separation of a magnetic suspension in a magnetic field.  Langmuir.  14(3).  578-581.
  • Palmer A, Cha B, Wirtz D (1998).  Structure and dynamics of actin filament solutions in the presence of latrunculin A.  Journal of Polymer Science, Part B: Polymer Physics.  36(17).
  • Cha B, Palmer A, Wirtz D (1998).  Structure and dynamics of actin filament solutions in the presence of latrunculin A.  Journal of Polymer Science, Part B: Polymer Physics.  36(17).  3007-3015.
  • Palmer A, Wirtz D, Xu J (1998).  High-frequency viscoelasticity of crosslinked actin filament networks measured by diffusing wave spectroscopy.  Rheologica Acta.  37(2).  97-106.
  • Palmer A, Wirtz D, Xu J (1998).  Rheology and microrheology of semiflexible polymer solutions: Actin filament networks.  Macromolecules.  31(19).  6486-6492.
  • Palmer A, Xu J, Wirtz D (1998).  High-frequency viscoelasticity of crosslinked actin filament networks measured by diffusing wave spectroscopy.  Rheologica Acta.  37(2).
  • Mason TG, Ganesan K, Van Zanten JH, Wirtz D, Kuo SC (1997).  Particle tracking microrheology of complex fluids.  Physical Review Letters.  79(17).
  • Mason TG, Dhople A, Wirtz D (1997).  Concentrated DNA rheology and microrheology.  Materials Research Society Symposium - Proceedings.  463.
  • Silva AS, Bond R, Plouraboué F, Wirtz D (1996).  Fluctuation dynamics of a single magnetic chain.  Physical Review E - Statistical Physics, Plasmas, Fluids, and Related Interdisciplinary Topics.  54(5).
  • Wirtz D (1995).  Direct measurement of the transport properties of a single DNA molecule.  Physical Review Letters.  75(12).
  • Wirtz D (1995).  Direct measurement of the transport properties of a single DNA molecule.  Physical Review Letters.  75(12).  2436-2439.
  • Fermigier M, Wirtz D (1995).  Periodic structures and substructures in magnetic suspensions.  Langmuir.  11(2).  398-400.
  • Wirtz D, Fermigier M (1995).  Periodic Structures and Substructures in Magnetic Suspensions.  Langmuir.  11(2).
  • Wirtz D (1994).  Fluctuation enhancement and reduction in sheared polymer solutions.  Macromolecules.  27(20).
  • Wirtz D (1994).  Flow-induced scattering peak in the structure factor of polymer solutions.  Physical Review E.  50(3).  R1755-R1758.
  • Wirtz D (1994).  Flow-induced scattering peak in the structure factor of polymer solutions.  Physical Review E.  50(3).
  • Wirtz D, Werner DE, Fuller GG (1994).  Structure and optical anisotropies of critical polymer solutions in electric fields.  The Journal of Chemical Physics.  101(2).
  • Wirtz D, Fermigier M (1994).  One-dimensional patterns and wavelength selection in magnetic fluids.  Physical Review Letters.  72(14).
  • Fermigier M, Wirtz D (1994).  Erratum: "One-dimensional patterns and wavelength selection in magnetic fluids" (Physical Review Letters (1994) 72, 24, (2294)).  Physical Review Letters.  72(24).  3919.
  • Wirtz D (1994).  Fluctuation enhancement and reduction in sheared polymer solutions.  Macromolecules.  27(20).  5639-5642.
  • Wirtz D, Fuller GG (1993).  Phase transitions induced by electric fields in near-critical polymer solutions.  Physical Review Letters.  71(14).
  • Fuller G, Wirtz D (1993).  Phase transitions induced by electric fields in near-critical polymer solutions.  Physical Review Letters.  71(14).  2236-2239.
  • Wirtz D, Berend K, Fuller GG (1992).  Electric-field-induced structure in polymer solutions near the critical point.  Macromolecules.  25(26).
  • Berend K, Fuller G, Wirtz D (1992).  Electric-field-induced structure in polymer solutions near the critical point.  Macromolecules.  25(26).  7234-7246.
  • Wirtz D, Kim D (2014).  Cytoskeletal tension induces the 3D polarized architecture of the nucleus.  Biomaterials.
  • Wirtz D, Giri A, Wu P (2014).  Statistical analysis of cell migration in 3D using the anisotropic persistent random walk model.  Nature Protocols.
  • Bhujwalla Z, Stasinopoulos I, Yoon A, Kim J, Kilic O, Yong H, An S (2014).  COX-2 dependent regulation of mechanotransduction in human breast cancer cells.  Cancer Biology and Therapy.
Books
  • Wirtz D (2012).  Introduction.  Comprehensive Biophysics.  7.  1-1.
  • Wirtz D (2012).  Biophysics of molecular cell mechanics.  Comprehensive Biophysics.  7.  104-121.
  • Cheung LS, Raman P, Wirtz D, Konstantopoulos K (2012).  Biophysics of selectin-mediated cell adhesion.  Comprehensive Biophysics.  7.  10-32.
Book Chapters
  • Kim DH, Hah J, Wirtz D (2018).  Mechanics of the cell nucleus.  Advances in Experimental Medicine and Biology.  1092.
  • Wirtz D (2012).  Introduction.  Comprehensive Biophysics.  7.
  • Wirtz D (2012).  Biophysics of molecular cell mechanics.  Comprehensive Biophysics.  7.
  • Cheung LSL, Raman PS, Wirtz D, Konstantopoulos K (2012).  Biophysics of selectin-mediated cell adhesion.  Comprehensive Biophysics.  7.
  • Dobrowsky TM, Wirtz D (2011).  Single-molecule analysis of cell-virus binding interactions.  Cell Signaling Reactions: Single-Molecular Kinetic Analysis.
Conference Proceedings
  • Wirtz D (2005).  Live-cell microrheology.  AIChE Annual Meeting, Conference Proceedings.  1132.
  • Dawson M, Wirtz D, Hanes J (2004).  Microscopic viscoelasticity of CF sputum determined by high-resolution nanoparticle tracking.  AIChE Annual Meeting, Conference Proceedings.  1315-1316.
  • Dawson M, Wirtz D, Hanes J (2004).  Gene carriers modified with PEG demonstrate increased transport and stability in mucus as explored with high-resolution nanoparticle tracking.  AIChE Annual Meeting, Conference Proceedings.  1263.
  • Dawson M, Wirtz D, Hanes J (2004).  Gene carriers modified with PEG demonstrate increased transport and stability in mucus as explored with high-resolution nanoparticle tracking.  AIChE Annual Meeting, Conference Proceedings.  8383.
  • Dawson M, Wirtz D, Hanes J (2004).  Gene carriers modified with PEG demonstrate increased transport and stability in mucus as explored with high-resolution nanoparticle tracking.  AIChE Annual Meeting, Conference Proceedings.  6345.
  • Wirtz D (2001).  Regulation of cell-matrix adhesion strength by cytoskeleton re-organization.  American Society of Mechanical Engineers, Bioengineering Division (Publication) BED.  50.  659-660.
  • Bao G, LeDuc P, Tsourkas A, Wirtz D (1999).  Dynamics of individual deoxyribonucleic acid molecules visualized in situ with shear strain.  Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings.  2.  1194.
  • Dhople A, Mason T, Wirtz D (1997).  Concentrated DNA rheology and microrheology.  Materials Research Society Symposium - Proceedings.  463.  153-158.
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