Popel, Aleksander

Professor
Som Biomedical Engineering

Traylor 611
(410) 955-6419
apopel@jhu.edu

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About

Experience
  • 2013 - Present:  JOINT/SECONDARY FACULTY, SOM Oncology Center
  • 2013 - Present:  JOINT/SECONDARY FACULTY, SOM Medicine
  • 2009 - Present:  Professor, SOM Oncology Center
  • 2007 - Present:  Professor, SOM Medicine

Publications

Journal Articles
  • Gkontra P, Norton KA, Zak MM, Clemente C, Agüero J, Ibáñez B, Santos A, Popel AS, Arroyo AG (2018).  Deciphering microvascular changes after myocardial infarction through 3D fully automated image analysis.  Scientific Reports.  8(1).
  • Bazzazi H, Zhang Y, Jafarnejad M, Popel AS (2018).  Computational modeling of synergistic interaction between αVβ3 integrin and VEGFR2 in endothelial cells: Implications for the mechanism of action of angiogenesis-modulating integrin-binding peptides.  Journal of Theoretical Biology.  455.
  • Zhang Y, Bazzazi H, Lima E Silva R, Pandey NB, Green JJ, Campochiaro PA, Popel AS (2018).  Three-Dimensional Transport Model for Intravitreal and Suprachoroidal Drug Injection.  Investigative ophthalmology & visual science.  59(12).
  • Norton KA, Jin K, Popel AS (2018).  Modeling triple-negative breast cancer heterogeneity: Effects of stromal macrophages, fibroblasts and tumor vasculature.  Journal of Theoretical Biology.  452.
  • Jin K, Pandey NB, Popel AS (2018).  Simultaneous blockade of IL-6 and CCL5 signaling for synergistic inhibition of triple-negative breast cancer growth and metastasis.  Breast Cancer Research.  20(1).
  • Bressler EM, Kim J, Shmueli RB, Mirando AC, Bazzazi H, Lee E, Popel AS, Pandey NB, Green JJ (2018).  Biomimetic peptide display from a polymeric nanoparticle surface for targeting and antitumor activity to human triple-negative breast cancer cells.  Journal of Biomedical Materials Research - Part A.  106(6).
  • Bazzazi H, Zhang Y, Jafarnejad M, Isenberg JS, Annex BH, Popel AS (2018).  Computer simulation of TSP1 inhibition of VEGF-Akt-eNOS: An angiogenesis triple threat.  Frontiers in Physiology.  9(MAY).
  • Zhao C, Isenberg JS, Popel AS (2018).  Human expression patterns: qualitative and quantitative analysis of thrombospondin-1 under physiological and pathological conditions.  Journal of Cellular and Molecular Medicine.  22(4).
  • Kim J, Mirando AC, Popel AS, Green JJ (2017).  Gene delivery nanoparticles to modulate angiogenesis.  Advanced Drug Delivery Reviews.  119.
  • Gong C, Milberg O, Wang B, Vicini P, Narwal R, Roskos L, Popel AS (2017).  A computational multiscale agent-based model for simulating spatio-temporal tumour immune response to PD1 and PDL1 inhibition.  Journal of the Royal Society Interface.  14(134).
  • Norton KA, Wallace T, Pandey NB, Popel AS (2017).  An agent-based model of triple-negative breast cancer: The interplay between chemokine receptor CCR5 expression, cancer stem cells, and hypoxia.  BMC Systems Biology.  11(1).
  • Bazzazi H, Isenberg JS, Popel AS (2017).  Inhibition of VEGFR2 activation and its downstream signaling to ERK1/2 and calcium by thrombospondin-1 (TSP1): In silico investigation.  Frontiers in Physiology.  8(FEB).
  • Bazzazi H, Popel AS (2017).  Computational investigation of sphingosine kinase 1 (SphK1) and calcium dependent ERK1/2 activation downstream of VEGFR2 in endothelial cells.  PLoS Computational Biology.  13(2).
  • Lima e Silva R, Kanan Y, Mirando AC, Kim J, Shmueli RB, Lorenc VE, Fortmann SD, Sciamanna J, Pandey NB, Green JJ, Popel AS, Campochiaro PA (2017).  Tyrosine kinase blocking collagen IV-derived peptide suppresses ocular neovascularization and vascular leakage.  Science Translational Medicine.  9(373).
  • Zhao C, Isenberg JS, Popel AS (2017).  Transcriptional and Post-Transcriptional Regulation of Thrombospondin-1 Expression: A Computational Model.  PLoS Computational Biology.  13(1).
  • Dvinsky AS, Popel AS (2017).  Motion of a rigid cylinder between parallel plates in Stokes flow. Part 2: Poiseuille and Couette flow..  INT. J. NUMER. METHODS FLUIDS.  7(8 , Aug. 1987).
  • Barbhuiya MA, Mirando AC, Simons BW, Lemtiri-Chlieh G, Green JJ, Popel AS, Pandey NB, Tran PT (2017).  Therapeutic potential of an anti-angiogenic multimodal biomimetic peptide in hepatocellular carcinoma.  Oncotarget.  8(60).
  • Jin K, Pandey NB, Popel AS (2017).  Crosstalk between stromal components and tumor cells of TNBC via secreted factors enhances tumor growth and metastasis.  Oncotarget.  8(36).
  • Dore-Savard L, Lee E, Kakkad S, Popel AS, Bhujwalla ZM (2016).  The Angiogenic Secretome in VEGF overexpressing Breast Cancer Xenografts.  Scientific Reports.  6.
  • Chu LH, Ganta VC, Choi MH, Chen G, Finley SD, Annex BH, Popel AS (2016).  A multiscale computational model predicts distribution of anti-angiogenic isoform VEGF165bin peripheral arterial disease in human and mouse.  Scientific Reports.  6.
  • Norton KA, Popel AS (2016).  Effects of endothelial cell proliferation and migration rates in a computational model of sprouting angiogenesis.  Scientific Reports.  6.
  • Yankeelov TE, An G, Saut O, Luebeck EG, Popel AS, Ribba B, Vicini P, Zhou X, Weis JA, Ye K, Genin GM (2016).  Multi-scale Modeling in Clinical Oncology: Opportunities and Barriers to Success.  Annals of Biomedical Engineering.  44(9).
  • Clancy CE, An G, Cannon WR, Liu Y, May EE, Ortoleva P, Popel AS, Sluka JP, Su J, Vicini P, Zhou X, Eckmann DM (2016).  Multiscale Modeling in the Clinic: Drug Design and Development.  Annals of Biomedical Engineering.  44(9).
  • Noren DP, Chou WH, Lee SH, Qutub AA, Warmflash A, Wagner DS, Popel AS, Levchenko A (2016).  Endothelial cells decode VEGF-mediated Ca2+ signaling patterns to produce distinct functional responses.  Science Signaling.  9(416).
  • Zhao C, Popel AS (2015).  Computational Model of MicroRNA Control of HIF-VEGF Pathway: Insights into the Pathophysiology of Ischemic Vascular Disease and Cancer.  PLoS Computational Biology.  11(11).
  • Finley SD, Angelikopoulos P, Koumoutsakos P, Popel AS (2015).  Pharmacokinetics of Anti-VEGF Agent aflibercept in cancer predicted by data-driven, molecular-detailed model.  CPT: Pharmacometrics and Systems Pharmacology.  4(11).
  • Chu LH, Vijay CG, Annex BH, Bader JS, Popel AS (2015).  PADPIN: Protein-protein interaction networks of angiogenesis, arteriogenesis, and inflammation in peripheral arterial disease.  Physiological Genomics.  47(8).
  • Fertig EJ, Lee E, Pandey NB, Popel AS (2015).  Analysis of gene expression of secreted factors associated with breast cancer metastases in breast cancer subtypes.  Scientific Reports.  5.
  • Gkontra P, Zak MM, Norton KA, Santos A, Popel AS, Arroyo AG (2015).  A 3D fractal-based approach towards understanding changes in the infarcted heart microvasculature.  Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics).  9351.
  • Lee E, Pandey NB, Popel AS (2015).  Crosstalk between cancer cells and blood endothelial and lymphatic endothelial cells in tumour and organ microenvironment.  Expert Reviews in Molecular Medicine.  17.
  • Norton KA, Popel AS, Pandey NB (2015).  Heterogeneity of chemokine cell-surface receptor expression in triple-negative breast cancer.  American Journal of Cancer Research.  5(4).
  • Chu LH, Annex BH, Popel AS (2015).  Computational drug repositioning for peripheral arterial disease: Prediction of anti-inflammatory and pro-angiogenic therapeutics.  Frontiers in Pharmacology.  6(Aug).
  • Kim E, Lee E, Plummer C, Gil S, Popel AS, Pathak AP (2015).  Vasculature-specific MRI reveals differential anti-angiogenic effects of a biomimetic peptide in an orthotopic breast cancer model.  Angiogenesis.  18(2).
  • Finley SD, Chu LH, Popel AS (2015).  Computational systems biology approaches to anti-angiogenic cancer therapeutics.  Drug Discovery Today.  20(2).
  • Rosca EV, Penet MF, Mori N, Koskimaki JE, Lee E, Pandey NB, Bhujwalla ZM, Popel AS (2014).  A biomimetic collagen derived peptide exhibits anti- Angiogenic activity in triple negative breast cancer.  PLoS ONE.  9(11).
  • Norton KA, Popel AS (2014).  An agent-based model of cancer stem cell initiated avascular tumour growth and metastasis: The effect of seeding frequency and location.  Journal of the Royal Society Interface.  11(100).
  • Chu LH, Lee E, Bader JS, Popel AS (2014).  Angiogenesis interactome and time course microarray data reveal the distinct activation patterns in endothelial cells.  PLoS ONE.  9(10).
  • Lee E, Fertig EJ, Jin K, Sukumar S, Pandey NB, Popel AS (2014).  Breast cancer cells condition lymphatic endothelial cells within pre-metastatic niches to promote metastasis.  Nature Communications.  5.
  • Lee E, Pandey NB, Popel AS (2014).  Lymphatic endothelial cells support tumor growth in breast cancer.  Scientific Reports.  4.
  • Imoukhuede PI, Popel AS (2014).  Quantitative fluorescent profiling of VEGFRs reveals tumor cell and endothelial cell heterogeneity in breast cancer xenografts.  Cancer medicine.  3(2).
  • Logsdon EA, Finley SD, Popel AS, MacGabhann F (2014).  A systems biology view of blood vessel growth and remodelling.  Journal of Cellular and Molecular Medicine.  18(8).
  • Lee E, Pandey NB, Popel AS (2014).  Pre-treatment of mice with tumor-conditioned media accelerates metastasis to lymph nodes and lungs: A new spontaneous breast cancer metastasis model.  Clinical and Experimental Metastasis.  31(1).
  • Vempati P, Popel AS, Mac Gabhann F (2014).  Extracellular regulation of VEGF: Isoforms, proteolysis, and vascular patterning.  Cytokine and Growth Factor Reviews.  25(1).
  • Lee E, Lee SJ, Koskimaki JE, Han Z, Pandey NB, Popel AS (2014).  Inhibition of breast cancer growth and metastasis by a biomimetic peptide.  Scientific Reports.  4.
  • Norton KA, Han Z, Popel AS, Pandey NB (2014).  Antiangiogenic cancer drug sunitinib exhibits unexpected proangiogenic effects on endothelial cells.  OncoTargets and Therapy.  7.
  • Stamatelos SK, Kim E, Pathak AP, Popel AS (2014).  A bioimage informatics based reconstruction of breast tumor microvasculature with computational blood flow predictions.  Microvascular Research.  91.
  • Finley SD, Dhar M, Popel AS (2013).  Compartment model predicts VEGF secretion and investigates the effects of VEGF Trap in tumor-bearing mice.  Frontiers in Oncology.  3 JUL.
  • Tan WH, Popel AS, Mac Gabhann F (2013).  Computational model of VEGFR2 pathway to ERK activation and modulation through receptor trafficking.  Cellular Signalling.  25(12).
  • Shmueli RB, Ohnaka M, Miki A, Pandey NB, Lima e Silva R, Koskimaki JE, Kim J, Popel AS, Campochiaro PA, Green JJ (2013).  Long-term suppression of ocular neovascularization by intraocular injection of biodegradable polymeric particles containing aserpin-derived peptide.  Biomaterials.  34(30).
  • Tan WH, Popel AS, Mac Gabhann F (2013).  Computational Model of Gab1/2-Dependent VEGFR2 Pathway to Akt Activation.  PLoS ONE.  8(6).
  • Imoukhuede PI, Dokun AO, Annex BH, Popel AS (2013).  Endothelial cell-by-cell profiling reveals the temporal dynamics of VEGFR1 and VEGFR2 membrane localization after murine hindlimb ischemia.  American Journal of Physiology - Heart and Circulatory Physiology.  304(8).
  • Finley SD, Popel AS (2013).  Effect of tumor microenvironment on tumor VEGF during anti-VEGF treatment: Systems biology predictions.  Journal of the National Cancer Institute.  105(11).
  • Lee E, Koskimaki JE, Pandey NB, Popel AS (2013).  Inhibition of lymphangiogenesis and angiogenesis in breast tumor xenografts and lymph nodes by a peptide derived from transmembrane protein 45A.  Neoplasia (United States).  15(2).
  • Koskimaki JE, Lee E, Chen W, Rivera CG, Rosca EV, Pandey NB, Popel AS (2013).  Synergy between a collagen IV mimetic peptide and a somatotropin-domain derived peptide as angiogenesis and lymphangiogenesis inhibitors.  Angiogenesis.  16(1).
  • Kim E, Stamatelos S, Cebulla J, Bhujwalla ZM, Popel AS, Pathak AP (2012).  Multiscale imaging and computational modeling of blood flow in the tumor vasculature.  Annals of Biomedical Engineering.  40(11).
  • Chu LH, Rivera CG, Popel AS, Bader JS (2012).  Constructing the angiome: A global angiogenesis protein interaction network.  Physiological Genomics.  44(19).
  • Liu G, Mac Gabhann F, Popel AS (2012).  Effects of Fiber Type and Size on the Heterogeneity of Oxygen Distribution in Exercising Skeletal Muscle.  PLoS ONE.  7(9).
  • Imoukhuede PI, Popel AS (2012).  Expression of VEGF Receptors on Endothelial Cells in Mouse Skeletal Muscle.  PLoS ONE.  7(9).
  • Finley SD, Popel AS (2012).  Predicting the effects of anti-angiogenic agents targeting specific VEGF isoforms.  AAPS Journal.  14(3).
  • Rosca EV, Lal B, Koskimaki JE, Popel AS, Laterra J (2012).  Collagen IV and CXC chemokine-derived antiangiogenic peptides suppress glioma xenograft growth.  Anti-Cancer Drugs.  23(7).
  • Rosca EV, Koskimaki JE, Pandey NB, Tamiz AP, Popel AS (2012).  Structure-Activity Relationship Study of Collagen-Derived Anti-Angiogenic Biomimetic Peptides.  Chemical Biology and Drug Design.  80(1).
  • Li X, Popel AS, Karniadakis GE (2012).  Bloodplasma separation in Y-shaped bifurcating microfluidic channels: A dissipative particle dynamics simulation study.  Physical Biology.  9(2).
  • Stefanini MO, Qutub AA, Mac Gabhann F, Popel AS (2012).  Computational models of VEGF-associated angiogenic processes in cancer.  Mathematical Medicine and Biology.  29(1).
  • Koskimaki JE, Rosca EV, Rivera CG, Lee E, Chen W, Pandey NB, Popel AS (2012).  Serpin-derived peptides are antiangiogenic and suppress breast tumor xenograft growth.  Translational Oncology.  5(2).
  • Lee E, Rosca EV, Pandey NB, Popel AS (2011).  Small peptides derived from somatotropin domain-containing proteins inhibit blood and lymphatic endothelial cell proliferation, migration, adhesion and tube formation.  International Journal of Biochemistry and Cell Biology.  43(12).
  • Finley SD, Engel-Stefanini MO, Imoukhuede PI, Popel AS (2011).  Pharmacokinetics and pharmacodynamics of VEGF-neutralizing antibodies.  BMC Systems Biology.  5.
  • Yen P, Finley SD, Engel-Stefanini MO, Popel AS (2011).  A two-compartment model of VEGF distribution in the mouse.  PLoS ONE.  6(11).
  • Rosca EV, Koskimaki JE, Pandey NB, Wolff AC, Popel AS (2011).  Development of a biomimetic peptide derived from collagen IV with anti-angiogenic activity in breast cancer.  Cancer Biology and Therapy.  12(9).
  • Rivera CG, Rosca EV, Pandey NB, Koskimaki JE, Bader JS, Popel AS (2011).  Novel peptide-specific quantitative structure-activity relationship (QSAR) analysis applied to collagen IV peptides with antiangiogenic activity.  Journal of Medicinal Chemistry.  54(19).
  • Rivera CG, Mellberg S, Claesson-Welsh L, Bader JS, Popel AS (2011).  Analysis of VEGF-A regulated gene expression in endothelial cells to identify genes linked to angiogenesis.  PLoS ONE.  6(9).
  • Rosca EV, Koskimaki JE, Rivera CG, Pandey NB, Tamiz AP, Popel AS (2011).  Anti-angiogenic peptides for cancer therapeutics.  Current Pharmaceutical Biotechnology.  12(8).
  • Rivera CG, Bader JS, Popel AS (2011).  Angiogenesis-associated crosstalk between collagens, CXC chemokines, and thrombospondin domain-containing proteins.  Annals of Biomedical Engineering.  39(8).
  • Vempati P, Popel AS, Mac Gabhann F (2011).  Formation of VEGF isoform-specific spatial distributions governing angiogenesis: computational analysis.  BMC Systems Biology.  5.
  • Liu G, Qutub AA, Vempati P, Mac Gabhann F, Popel AS (2011).  Module-based multiscale simulation of angiogenesis in skeletal muscle.  Theoretical Biology and Medical Modelling.  8(1).
  • Imoukhuede PI, Popel AS (2011).  Quantification and cell-to-cell variation of vascular endothelial growth factor receptors.  Experimental Cell Research.  317(7).
  • Waters SL, Alastruey J, Beard DA, Bovendeerd PHM, Davies PF, Jayaraman G, Jensen OE, Lee J, Parker KH, Popel AS, Secomb TW, Siebes M, Sherwin SJ, Shipley RJ, Smith NP, van de Vosse FN (2011).  Theoretical models for coronary vascular biomechanics: Progress & challenges.  Progress in Biophysics and Molecular Biology.  104(1-3).
  • Stefanini MO, Wu FTH, Mac Gabhann F, Popel AS (2010).  Increase of plasma VEGF after intravenous administration of bevacizumab is predicted by a pharmacokinetic model.  Cancer Research.  70(23).
  • Fedosov DA, Caswell B, Popel AS, Karniadakis GEM (2010).  Blood Flow and Cell-Free Layer in Microvessels.  Microcirculation.  17(8).
  • Gabhann FM, Qutub AA, Annex BH, Popel AS (2010).  Systems biology of pro-angiogenic therapies targeting the VEGF system.  Wiley Interdisciplinary Reviews: Systems Biology and Medicine.  2(6).
  • Gabhann FM, Annex BH, Popel AS (2010).  Gene therapy from the perspective of systems biology.  Current Opinion in Molecular Therapeutics.  12(5).
  • Vempati P, Mac Gabhann F, Popel AS (2010).  Quantifying the proteolytic release of extracellular matrix-sequestered VEGF with a computational model.  PLoS ONE.  5(7).
  • Wu FTH, Stefanini MO, Mac Gabhann F, Kontos CD, Annex BH, Popel AS (2010).  VEGF and soluble VEGF receptor-1 (sFlt-1) distributions in peripheral arterial disease: An in silico model.  American Journal of Physiology - Heart and Circulatory Physiology.  298(6).
  • Wu FTH, Stefanini MO, Gabhann FM, Kontos CD, Annex BH, Popel AS (2010).  A systems biology perspective on sVEGFR1: Its biological function, pathogenic role and therapeutic use.  Journal of Cellular and Molecular Medicine.  14(3).
  • Koskimaki JE, Karagiannis ED, Tang BC, Hammers H, Watkins DN, Pili R, Popel AS (2010).  Pentastatin-1, a collagen IV derived 20-mer peptide, suppresses tumor growth in a small cell lung cancer xenograft model.  BMC Cancer.  10.
  • Wu FTH, Stefanini MO, Gabhann FM, Popel AS (2009).  Chapter 18 Modeling of Growth Factor-Receptor Systems. From Molecular-Level Protein Interaction Networks to Whole-Body Compartment Models.  Methods in Enzymology.  467(C).
  • Qutub AA, Liu G, Vempati P, Popel AS (2009).  Integration of angiogenesis modules at multiple scales: From molecular to tissue.  Pacific Symposium on Biocomputing 2009, PSB 2009.
  • Chung B, Kim S, Johnson PC, Popel AS (2009).  Computational fluid dynamics of aggregating red blood cells in postcapillary venules.  Computer Methods in Biomechanics and Biomedical Engineering.  12(4).
  • Stefanini MO, Wu FTH, Gabhann FM, Popel AS (2009).  The presence of VEGF receptors on the luminal surface of endothelial cells affects VEGF distribution and VEGF signaling.  PLoS Computational Biology.  5(12).
  • Cano MdV, Karagiannis ED, Soliman M, Bakir B, Zhuang W, Popel AS, Gehlbach PL (2009).  A peptide derived from type 1 thrombospondin repeat-containing protein WISP-1 inhibits corneal and choroidal neovascularization.  Investigative Ophthalmology and Visual Science.  50(8).
  • Schumacher K, Popel A, Anvari B, Brownell W, Spector A (2009).  Computational analysis of the tether pulling experiment to probe cellular membranes.  Proceedings of the ASME Summer Bioengineering Conference 2009, SBC2009.  (PART A).
  • Schumacher KR, Popel AS, Anvari B, Brownell WE, Spector AA (2009).  Computational analysis of the tether-pulling experiment to probe plasma membrane-cytoskeleton interaction in cells.  Physical Review E - Statistical, Nonlinear, and Soft Matter Physics.  80(4).
  • Popel AS, Hunter PJ (2009).  Systems biology and physiome projects.  Wiley Interdisciplinary Reviews: Systems Biology and Medicine.  1(2).
  • Chen K, Popel AS (2009).  Nitric oxide production pathways in erythrocytes and plasma.  Biorheology.  46(2).
  • Chen K, Pittman RN, Popel AS (2009).  Hemorrhagic shock and nitric oxide release from erythrocytic nitric oxide synthase: A quantitative analysis.  Microvascular Research.  78(1).
  • Wu FTH, Stefanini MO, Mac Gabhann F, Kontos CD, Annex BH, Popel AS (2009).  Computational kinetic model of VEGF trapping by soluble VEGF receptor-1: Effects of transendothelial and lymphatic macromolecular transport.  Physiological Genomics.  38(1).
  • Zhang J, Johnson PC, Popel AS (2009).  Effects of erythrocyte deformability and aggregation on the cell free layer and apparent viscosity of microscopic blood flows.  Microvascular Research.  77(3).
  • Wu FTH, Stefanini MO, Mac Gabhann F, Popel AS (2009).  A compartment model of VEGF distribution in humans in the presence of soluble VEGF receptor-1 acting as a ligand trap.  PLoS ONE.  4(4).
  • Qutub A, Gabhann F, Karagiannis E, Vempati P, Popel A (2009).  Multiscale models of angiogenesis.  IEEE Engineering in Medicine and Biology Magazine.  28(2).
  • Qutub AA, Popel AS (2009).  Elongation, proliferation and migration differentiate endothelial cell phenotypes and determine capillary sprouting.  BMC Systems Biology.  3.
  • Koskimaki JE, Karagiannis ED, Rosca EV, Vesuna F, Winnard PT, Raman V, Bhujwalla ZM, Popel AS (2009).  Peptides derived from type IV collagen, CXC chemokines, and thrombospondin-1 domain-containing proteins inhibit neovascularization and suppress tumor growth in MDA-MB-231 breast cancer xenografts.  Neoplasia.  11(12).
  • Gabhann FM, Popel AS (2008).  Systems biology of vascular endothelial growth factors.  Microcirculation.  15(8).
  • Karagiannis ED, Popel AS (2008).  A systematic methodology for proteome-wide identification of peptides inhibiting the proliferation and migration of endothelial cells.  Proceedings of the National Academy of Sciences of the United States of America.  105(37).
  • Sharan M, Vovenko EP, Vadapalli A, Popel AS, Pittman RN (2008).  Experimental and theoretical studies of oxygen gradients in rat pial microvessels.  Journal of Cerebral Blood Flow and Metabolism.  28(9).
  • Stefanini MO, Wu FTH, Mac Gabhann F, Popel AS (2008).  A compartment model of VEGF distribution in blood, healthy and diseased tissues.  BMC Systems Biology.  2.
  • Qutub AA, Popel AS (2008).  Reactive oxygen species regulate hypoxia-inducible factor 1α differentially in cancer and ischemia.  Molecular and Cellular Biology.  28(16).
  • Chen K, Pittman RN, Popel AS (2008).  Nitric oxide in the vasculature: Where does it come from and where does it go? A quantitative perspective.  Antioxidants and Redox Signaling.  10(7).
  • Karagiannis ED, Popel AS (2008).  Novel anti-angiogenic peptides derived from ELR-containing CXC chemokines.  Journal of Cellular Biochemistry.  104(4).
  • Schumacher KR, Popel AS, Anvari B, Brownell WE, Spector AA (2008).  Modeling the mechanics of tethers pulled from the cochlear outer hair cell membrane.  Journal of Biomechanical Engineering.  130(3).
  • Demetriades AM, Deering T, Liu H, Lu L, Gehlbach P, Packer JD, Gabhann FM, Popel AS, Wei LL, Campochiaro PA (2008).  Trans-scleral delivery of antiangiogenic proteins.  Journal of Ocular Pharmacology and Therapeutics.  24(1).
  • Chen K, Piknova B, Pittman RN, Schechter AN, Popel AS (2008).  Nitric oxide from nitrite reduction by hemoglobin in the plasma and erythrocytes.  Nitric Oxide - Biology and Chemistry.  18(1).
  • Zhang J, Johnson PC, Popel AS (2008).  Red blood cell aggregation and dissociation in shear flows simulated by lattice Boltzmann method.  Journal of Biomechanics.  41(1).
  • Vempati P, Karagiannis ED, Popel AS (2007).  A biochemical model of matrix metalloproteinase 9 activation and inhibition.  Journal of Biological Chemistry.  282(52).
  • Ji JW, Mac Gabhann F, Popel AS (2007).  Skeletal muscle VEGF gradients in peripheral arterial disease: Simulations of rest and exercise.  American Journal of Physiology - Heart and Circulatory Physiology.  293(6).
  • Tsoukias NM, Goldman D, Vadapalli A, Pittman RN, Popel AS (2007).  A computational model of oxygen delivery by hemoglobin-based oxygen carriers in three-dimensional microvascular networks.  Journal of Theoretical Biology.  248(4).
  • Kut C, Mac Gabhann F, Popel AS (2007).  Where is VEGF in the body? A meta-analysis of VEGF distribution in cancer.  British Journal of Cancer.  97(7).
  • Liao Z, Feng S, Popel AS, Brownell WE, Spector AA (2007).  Outer hair cell active force generation in the cochlear environment.  Journal of the Acoustical Society of America.  122(4).
  • Hazarika S, Dokun AO, Li Y, Popel AS, Kontos CD, Annex BH (2007).  Impaired angiogenesis after hindlimb ischemia in type 2 diabetes mellitus: Differential regulation of vascular endothelial growth factor receptor 1 and soluble vascular endothelial growth factor receptor 1.  Circulation Research.  101(9).
  • Karagiannis ED, Popel AS (2007).  Peptides derived from type I thrombospondin repeat-containing proteins of the CCN family inhibit proliferation and migration of endothelial cells.  International Journal of Biochemistry and Cell Biology.  39(12).
  • Qutub AA, Popel AS (2007).  Three autocrine feedback loops determine HIF1α expression in chronic hypoxia.  Biochimica et Biophysica Acta - Molecular Cell Research.  1773(10).
  • Kim S, Kong RL, Popel AS, Intaglietta M, Johnson PC (2007).  Temporal and spatial variations of cell-free layer width in arterioles.  American Journal of Physiology - Heart and Circulatory Physiology.  293(3).
  • Kim S, Zhen J, Popel AS, Intaglietta M, Johnson PC (2007).  Contributions of collision rate and collision efficiency to erythrocyte aggregation in postcapillary venules at low flow rates.  American Journal of Physiology - Heart and Circulatory Physiology.  293(3).
  • Chen K, Pittman RN, Popel AS (2007).  Vascular smooth muscle NO exposure from intraerythrocytic SNOHb: A mathematical model.  Antioxidants and Redox Signaling.  9(8).
  • Karagiannis ED, Popel AS (2007).  Anti-angiogenic peptides identified in thrombospondin type I domains.  Biochemical and Biophysical Research Communications.  359(1).
  • Mac Gabhann F, Popel AS (2007).  Dimerization of VEGF receptors and implications for signal transduction: A computational study.  Biophysical Chemistry.  128(2-3).
  • Das B, Bishop JJ, Kim S, Meiselman HJ, Johnson PC, Popel AS (2007).  Red blood cell velocity profiles in skeletal muscle venules at low flow rates are described by the Casson model.  Clinical Hemorheology and Microcirculation.  36(3).
  • Mac Gabhann F, Ji JW, Popel AS (2007).  Multi-scale computational models of pro-angiogenic treatments in peripheral arterial disease.  Annals of Biomedical Engineering.  35(6).
  • Zhi M, Ratnanather JT, Ceyhan E, Popel AS, Brownell WE (2007).  Hypotonic swelling of salicylate-treated cochlear outer hair cells.  Hearing Research.  228(1-2).
  • Mac Gabhann F, Demetriades AM, Deering T, Packer JD, Shah SM, Duh E, Campochiaro PA, Popel AS (2007).  Protein transport to choroid and retina following periocular injection: Theoretical and experimental study.  Annals of Biomedical Engineering.  35(4).
  • Chen K, Popel AS (2007).  Vascular and perivascular nitric oxide release and transport: Biochemical pathways of neuronal nitric oxide synthase (NOS1) and endothelial nitric oxide synthase (NOS3).  Free Radical Biology and Medicine.  42(6).
  • Karagiannis ED, Popel AS (2007).  Identification of novel short peptides derived from the α4, α5, and α6 fibrils of type IV collagen with anti-angiogenic properties.  Biochemical and Biophysical Research Communications.  354(2).
  • Mac Gabhann F, Ji JW, Popel AS (2007).  VEGF gradients, receptor activation, and sprout guidance in resting and exercising skeletal muscle.  Journal of Applied Physiology.  102(2).
  • Chung B, Johnson PC, Popel AS (2007).  Application of Chimera grid to modelling cell motion and aggregation in a narrow tube.  International Journal for Numerical Methods in Fluids.  53(1).
  • Mac Gabhann F, Popel AS (2007).  Interactions of VEGF isoforms with VEGFR-1, VEGFR-2, and neuropilin in vivo: A computational model of human skeletal muscle.  American Journal of Physiology - Heart and Circulatory Physiology.  292(1).
  • Zhang J, Johnson PC, Popel AS (2007).  An immersed boundary lattice Boltzmann approach to simulate deformable liquid capsules and its application to microscopic blood flows.  Physical Biology.  4(4).
  • Mac Gabhann F, Popel AS (2006).  Targeting neuropilin-1 to inhibit VEGF signaling in cancer: Comparison of therapeutic approaches.  PLoS Computational Biology.  2(12).
  • Qutub AA, Popel AS (2006).  A computational model of intracellular oxygen sensing by hypoxia-inducible factor HIF1α.  Journal of Cell Science.  119(16).
  • Chen K, Popel AS (2006).  Theoretical analysis of biochemical pathways of nitric oxide release from vascular endothelial cells.  Free Radical Biology and Medicine.  41(4).
  • Ji JW, Tsoukias NM, Goldman D, Popel AS (2006).  A computational model of oxygen transport in skeletal muscle for sprouting and splitting modes of angiogenesis.  Journal of Theoretical Biology.  241(1).
  • Kim S, Kong RL, Popel AS, Intaglietta M, Johnson PC (2006).  A computer-based method for determination of the cell-free layer width in microcirculation.  Microcirculation.  13(3).
  • Kim S, Popel AS, Intaglietta M, Johnson PC (2006).  Effect of erythrocyte aggregation at normal human levels on functional capillary density in rat spinotrapezius muscle.  American Journal of Physiology - Heart and Circulatory Physiology.  290(3).
  • Kavdia M, Popel AS (2006).  Venular endothelium-derived NO can affect paired arteriole: A computational model.  American Journal of Physiology - Heart and Circulatory Physiology.  290(2).
  • Karagiannis ED, Popel AS (2006).  Distinct modes of collagen type I proteolysis by matrix metalloproteinase (MMP) 2 and membrane type I MMP during the migration of a tip endothelial cell: Insights from a computational model.  Journal of Theoretical Biology.  238(1).
  • Gabhann FM, Ji JW, Popel AS (2006).  Computational model of vascular endothelial growth factor spatial distribution in muscle and pro-angiogenic cell therapy.  PLoS Computational Biology.  2(9).
  • Mac Gabhann F, Yang MT, Popel AS (2005).  Monte Carlo simulations of VEGF binding to cell surface receptors in vitro.  Biochimica et Biophysica Acta - Molecular Cell Research.  1746(2).
  • Liao Z, Popel AS, Brownell WE, Spector AA (2005).  High-frequency force generation in the constrained cochlear outer hair cell: A model study.  JARO - Journal of the Association for Research in Otolaryngology.  6(4).
  • Bagchi P, Johnson PC, Popel AS (2005).  Computational fluid dynamic simulation of aggregation of deformable cells in a shear flow.  Journal of Biomechanical Engineering.  127(7).
  • Liao Z, Popel AS, Brownell WE, Spector AA (2005).  Effect of voltage-dependent membrane properties on active force generation in cochlear outer hair cell.  Journal of the Acoustical Society of America.  118(6).
  • Spector AA, Popel AS, Eatock RA, Brownell WE (2005).  Mechanosensitive channels in the lateral wall can enhance the cochlear outer hair cell frequency response.  Annals of Biomedical Engineering.  33(8).
  • Mac Gabhann F, Popel AS (2005).  Differential binding of VEGF isoforms to VEGF receptor 2 in the presence of neuropilin-1: A computational model.  American Journal of Physiology - Heart and Circulatory Physiology.  288(6 57-6).
  • Liao Z, Popel AS, Brownell WE, Spector AA (2005).  Modeling high-frequency electromotility of cochlear outer hair cell in microchamber experiment.  Journal of the Acoustical Society of America.  117(4 I).
  • Popel AS, Johnson PC (2005).  Microcirculation and hemorheology.  Annual Review of Fluid Mechanics.  37.
  • Kim S, Popel AS, Intaglietta M, Johnson PC (2005).  Aggregate formation of erythrocytes in postcapillary venules.  American Journal of Physiology - Heart and Circulatory Physiology.  288(2 57-2).
  • Murdock DR, Ermilov SA, Spector AA, Popel AS, Brownell WE, Anvari B (2005).  Effects of chlorpromazine on mechanical properties of the outer hair cell plasma membrane.  Biophysical Journal.  89(6).
  • Filion RJ, Popel AS (2005).  Intracoronary administration of FGF-2: A computational model of myocardial deposition and retention.  American Journal of Physiology - Heart and Circulatory Physiology.  288(1 57-1).
  • Mac Gabhann F, Karagiannis ED, Popel AS (2004).  Building blocks for computational models of angiogenesis.  Conference Record - Asilomar Conference on Signals, Systems and Computers.  1.
  • Karagiannis ED, Popel AS (2004).  A theoretical model of type I collagen proteolysis by matrix metalloproteinase (MMP) 2 and membrane type 1 MMP in the presence of tissue inhibitor of metalloproteinase 2.  Journal of Biological Chemistry.  279(37).
  • Kavdia M, Popel AS (2004).  Contribution of nNOS- and eNOS-derived NO to microvascular smooth muscle NO exposure.  Journal of Applied Physiology.  97(1).
  • Filion RJ, Popel AS (2004).  A reaction-diffusion model of basic fibroblast growth factor interactions with cell surface receptors.  Annals of Biomedical Engineering.  32(5).
  • Tsoukias NM, Kavdia M, Popel AS (2004).  A theoretical model of nitric oxide transport in arterioles: Frequency- vs. amplitude-dependent control of cGMP formation.  American Journal of Physiology - Heart and Circulatory Physiology.  286(3 55-3).
  • Bishop JJ, Nance PR, Popel AS, Intaglietta M, Johnson PC (2004).  Relationship between erythrocyte aggregate size and flow rate in skeletal muscle venules.  American Journal of Physiology - Heart and Circulatory Physiology.  286(1 55-1).
  • Mac Gabhann F, Popel AS (2004).  Model of competitive binding of vascular endothelial growth factor and placental growth factor to VEGF receptors on endothelial cells.  American Journal of Physiology - Heart and Circulatory Physiology.  286(1 55-1).
  • Tsoukias NM, Popel AS (2003).  A model of nitric oxide capillary exchange.  Microcirculation.  10(6).
  • Popel AS, Goldman D, Vadapalli A (2003).  Modeling of oxygen diffusion from the blood vessels to intracellular organelles.  Advances in Experimental Medicine and Biology.  530.
  • Spector AA, Brownell WE, Popel AS (2003).  Effect of outer hair cell piezoelectricity on high-frequency receptor potentials.  Journal of the Acoustical Society of America.  113(1).
  • Kavdia M, Popel AS (2003).  Wall shear stress differentially affects NO level in arterioles for volume expanders and Hb-based O2carriers.  Microvascular Research.  66(1).
  • Spector AA, Brownell WE, Popel AS (2002).  Effect of outer hair cell membrane piezoelectric properties on the receptor potential under high-frequency conditions.  Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings.  1.
  • Bishop JJ, Popel AS, Intaglietta M, Johnson PC (2002).  Effect of aggregation and shear rate on the dispersion of red blood cells flowing in venules.  American Journal of Physiology - Heart and Circulatory Physiology.  283(5 52-5).
  • Kavdia M, Tsoukias NM, Popel AS (2002).  Model of nitric oxide diffusion in an arteriole: Impact of hemoglobin-based blood substitutes.  American Journal of Physiology - Heart and Circulatory Physiology.  282(6 51-6).
  • Tsoukias NM, Popel AS (2002).  Erythrocyte consumption of nitric oxide in presence and absence of plasma-based hemoglobin.  American Journal of Physiology - Heart and Circulatory Physiology.  282(6 51-6).
  • Vadapalli A, Goldman D, Popel AS (2002).  Calculations of oxygen transport by red blood cells and hemoglobin solutions in capillaries.  Artificial Cells, Blood Substitutes, and Immobilization Biotechnology.  30(3).
  • Spector AA, Ameen M, Charalambides PG, Popel AS (2002).  Nanostructure, effective properties, and deformation pattern of the cochlear outer hair cell cytoskeleton.  Journal of Biomechanical Engineering.  124(2).
  • Wootton DM, Popel AS, Alevriadou BR (2002).  An experimental and theoretical study on the dissolution of mural fibrin clots by tissue-type plasminogen activator.  Biotechnology and Bioengineering.  77(4).
  • Kavdia M, Pittman RN, Popel AS (2002).  Theoretical analysis of effects of blood substitute affinity and cooperativity on organ oxygen transport.  Journal of Applied Physiology.  93(6).
  • Sharan M, Popel AS (2002).  A compartmental model for oxygen transport in brain microcirculation in the presence of blood substitutes.  Journal of Theoretical Biology.  216(4).
  • Specter AA, Ameen M, Popel AS (2001).  Mechanics of the cochlear outer hair cell composite membrane.  American Society of Mechanical Engineers, Bioengineering Division (Publication) BED.  50.
  • Sharan M, Popel AS (2001).  A two-phase model for flow of blood in narrow tubes with increased effective viscosity near the wall.  Biorheology.  38(5-6).
  • Brownell WE, Spector AA, Raphael RM, Popel AS (2001).  Micro- and nanomechanics of the cochlear outer hair cell.  Annual Review of Biomedical Engineering.  3.
  • Bishop JJ, Nance PR, Popel AS, Intaglietta M, Johnson PC (2001).  Erythrocyte margination and sedimentation in skeletal muscle venules.  American Journal of Physiology - Heart and Circulatory Physiology.  281(2 50-2).
  • Bishop JJ, Popel AS, Intaglietta M, Johnson PC (2001).  Effects of erythrocyte aggregation and venous network geometry on red blood cell axial migration.  American Journal of Physiology - Heart and Circulatory Physiology.  281(2 50-2).
  • Bishop JJ, Popel AS, Intaglietta M, Johnson PC (2001).  Rheological effects of red blood cell aggregation in the venous network: A review of recent studies.  Biorheology.  38(2-3).
  • Bishop JJ, Nance PR, Popel AS, Intaglietta M, Johnson PC (2001).  Effect of erythrocyte aggregation on velocity profiles in venules.  American Journal of Physiology - Heart and Circulatory Physiology.  280(1 49-1).
  • Goldman D, Popel AS (2001).  A computational study of the effect of vasomotion on oxygen transport from capillary networks.  Journal of Theoretical Biology.  209(2).
  • Spector AA, Ameen M, Popel AS (2001).  Simulation of motor-driven cochlear outer hair cell electromotility.  Biophysical Journal.  81(1).
  • Spector A, Ameen M, Charalambides P, Popel A (2000).  Computational modeling of the cochlear outer hair cell cytoskeleton.  Annals of Biomedical Engineering.  28(SUPPL. 1).
  • Goldman D, Popel AS (2000).  Computational modeling of oxygen transport from complex capillary networks: Relation to the microcircalation physiome.  Advances in Experimental Medicine and Biology.  471.
  • Spector A, Ameen M, Popel A (2000).  Simulation of cochlear outer hair cell electromotility.  Annals of Biomedical Engineering.  28(SUPPL. 1).
  • Golub AS, Popel AS, Zheng L, Pittman RN (2000).  Analysis of phosphorescence decay for nonuniform oxygen tension: Consequences of finite excitation flash duration.  Advances in Experimental Medicine and Biology.  471.
  • Eggleton CD, Vadapalli A, Roy TK, Popel AS (2000).  Calculations of intracapillary oxygen tension distributions in muscle.  Mathematical Biosciences.  167(2).
  • Goldman D, Popel AS (2000).  A computational study of the effect of capillary network anastomoses and tortuosity on oxygen transport.  Journal of Theoretical Biology.  206(2).
  • Vadapalli A, Pittman RN, Popel AAS (2000).  Estimating oxygen transport resistance of the microvascular wall.  American Journal of Physiology - Heart and Circulatory Physiology.  279(2 48-2).
  • Das B, Johnson PC, Popel AS (2000).  Computational fluid dynamic studies of leukocyte adhesion effects on non-Newtonian blood flow through microvessels.  Biorheology.  37(3).
  • Bishop JJ, Nance PR, Popel AS, Intaglietta M, Johnson PC (2000).  Diameter changes in skeletal muscle venules during arterial pressure reduction.  American Journal of Physiology - Heart and Circulatory Physiology.  279(1 48-1).
  • Ratnanather JT, Popel AS, Brownell WE (2000).  An analysis of the hydraulic conductivity of the extracisternal space of the cochlear outer hair cell.  Journal of Mathematical Biology.  40(4).
  • Raphael RM, Popel AS, Brownell WE (2000).  A membrane bending model of outer hair cell electromotility.  Biophysical Journal.  78(6).
  • Goldman D, Popel AS (1999).  Computational model of oxygen transport applied to capillary networks in skeletal muscle.  American Society of Mechanical Engineers, Bioengineering Division (Publication) BED.  42.
  • Spector AA, Ameen M, Charalambides PG, Popel AS (1999).  Mechanical properties of the outer hair cell cytoskeleton: simulation of the microstructure and molecular organization.  American Society of Mechanical Engineers, Bioengineering Division (Publication) BED.  42.
  • Wootton DM, Popel AS, Alevriadou BR (1999).  Model of lysis of mural platelet-fibrin thrombi.  Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings.  2.
  • Johnson PC, Bishop JJ, Popel S, Intaglietta M (1999).  Effects of red cell aggregation on the venous microcirculation.  Biorheology.  36(5-6).
  • Pittman RN, Japee SA, Goldman D, Popel AS (1999).  Automated measurements of morphological, hemodynamic and oxygenation parameters in capillary networks and their use in computational models.  Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings.  2.
  • Gruben KG, Halperin HR, Popel AS, Tsitlik JE (1999).  Canine sternal force-displacement relationship during cardiopulmonary resuscitation.  IEEE Transactions on Biomedical Engineering.  46(7).
  • Popel AS, Pries AR, Slaaf DW (1999).  Microcirculation physiome project.  Journal of Vascular Research.  36(3).
  • Spector AA, Brownell WE, Popel AS (1999).  Nonlinear active force generation by cochlear outer hair cell.  Journal of the Acoustical Society of America.  105(4).
  • Golub AS, Popel AS, Zheng L, Pittman RN (1999).  Analysis of phosphorescence decay in heterogeneous systems: Consequences of finite excitation flash duration.  Photochemistry and Photobiology.  69(6).
  • Spector AA, Brownell WE, Popel AS (1999).  Mechanical and electromotile characteristics of auditory outer hair cells.  Medical and Biological Engineering and Computing.  37(2).
  • Sharan M, Gupta S, Popel AS (1998).  Parametric analysis of the relationship between end-capillary and mean tissue PO2 as predicted by a mathematical model.  Journal of Theoretical Biology.  195(4).
  • Spector AA, Brownell WE, Popel AS (1998).  Elastic properties of the composite outer hair cell wall.  Annals of Biomedical Engineering.  26(1).
  • Eggleton CD, Roy TK, Popel AS (1998).  Predictions of capillary oxygen transport in the presence of fluorocarbon additives.  American Journal of Physiology - Heart and Circulatory Physiology.  44(6).
  • Pittman RN, Golub AS, Popel AS, Zheng L (1998).  Interpretation of phosphorescence quenching measurements made in the presence of oxygen gradients.  Advances in Experimental Medicine and Biology.  454.
  • Eggleton CD, Roy TK, Popel AS (1998).  Predictions of capillary oxygen transport in the presence of fluorocarbon additives.  American Journal of Physiology - Heart and Circulatory Physiology.  275(6 44-6).
  • Das B, Johnson PC, Popel AS (1998).  Effect of nonaxisymmetric hematocrit distribution on non-Newtonian blood flow in small tubes.  Biorheology.  35(1).
  • Spector AA, Brownell WE, Popel AS (1998).  Estimation of elastic moduli and bending stiffness of the anisotropic outer hair cell wall.  Journal of the Acoustical Society of America.  103(2).
  • Spector AA, Brownell WE, Popel AS (1998).  Analysis of the micropipet experiment with the anisotropic outer hair cell wall.  Journal of the Acoustical Society of America.  103(2).
  • Sharan M, Popel AS, Hudak ML, Koehler RC, Traystman RJ, Jones MD (1998).  An analysis of hypoxia in sheep brain using a mathematical model.  Annals of Biomedical Engineering.  26(1).
  • Eggleton CD, Popel AS (1998).  Large deformation of red blood cell ghosts in a simple shear flow.  Physics of Fluids.  10(8).
  • Popel AS, Greene AS, Ellis CG, Ley KF, Skalak TC, Tonellato PJ (1998).  The Microcirculation Physiome Project..  Annals of biomedical engineering.  26(6).
  • Das B, Enden G, Popel AS (1997).  Stratified multiphase model for blood flow in a venular bifurcation.  Annals of Biomedical Engineering.  25(1).
  • Cabel M, Meiselman HJ, Popel AS, Johnson PC (1997).  Contribution of red blood cell aggregation to venous vascular resistance in skeletal muscle.  American Journal of Physiology - Heart and Circulatory Physiology.  272(2 41-2).
  • Cabel M, Meiselman HJ, Popel AS, Johnson PC (1997).  Contribution of red blood cell aggregation to venous vascular resistance in skeletal muscle.  American Journal of Physiology - Heart and Circulatory Physiology.  41(2).
  • Sit PS, Spector AA, Lue AJC, Popel AS, Brownell WE (1997).  Micropipette aspiration on the outer hair cell lateral wall.  Biophysical Journal.  72(6).
  • Golub AS, Popel AS, Zheng L, Pittman RN (1997).  Analysis of phosphorescence in heterogeneous systems using distributions of quencher concentration.  Biophysical Journal.  73(1).
  • Spector AA, Brownell WE, Popel AS (1997).  Estimation of elastic characteristics of the auditory outer hair cell.  American Society of Mechanical Engineers, Bioengineering Division (Publication) BED.  35.
  • Spector AA, Brownell WE, Popel AS (1996).  A model for cochlear outer hair cell deformations in micropipette aspiration experiments: An analytical solution.  Annals of Biomedical Engineering.  24(2).
  • Spector AA, Brownell WE, Popel AS (1996).  An elastic model of a composite cell membrane: interpretation and design of experiments.  American Society of Mechanical Engineers, Bioengineering Division (Publication) BED.  33.
  • Jerry RA, Popel AS, Brownell WE (1996).  Potential distribution for a spheroidal cell having a conductive membrane in an electric field.  IEEE Transactions on Biomedical Engineering.  43(9).
  • Roy TK, Popel AS (1996).  Theoretical predictions of end-capillary PO2in muscles of athletic and nonathletic animals at V̇O(2max).  American Journal of Physiology - Heart and Circulatory Physiology.  271(2 40-2).
  • Roy TK, Popel AS (1996).  Theoretical predictions of end-capillary PO2 in muscles of athletic and nonathletic animals at V̇O2max.  American Journal of Physiology - Heart and Circulatory Physiology.  40(2).
  • Ratnanather JT, Zhi M, Brownell WE, Popel AS (1996).  The ratio of elastic moduli of cochlear outer hair cells derived from osmotic experiments.  Journal of the Acoustical Society of America.  99(2).
  • Dutta A, Wang L, Meng H, Pittman RN, Popel AS (1996).  Oxygen tension profiles in isolated hamster retractor muscle at different temperatures.  Microvascular Research.  51(3).
  • Ratnanather JT, Zhi M, Brownell WE, Popel AS (1996).  Measurements and a model of the outer hair cell hydraulic conductivity.  Hearing Research.  96(1-2).
  • Spector AA, Brownell WE, Popel AS (1995).  Mechanical model of the outer hair cell wall.  American Society of Mechanical Engineers, Bioengineering Division (Publication) BED.  31.
  • Dutta A, Popel AS (1995).  A Theoretical Analysis of Intracellular Oxygen Diffusion.  Journal of Theoretical Biology.  176(4).
  • Jerry RA, Popel AS, Brownell WE (1995).  Outer hair cell length changes in an external electric field. I. The role of intracellular electro-osmotically generated pressure gradients.  Journal of the Acoustical Society of America.  98(4).
  • Jerry RA, Popel AS, Brownell WE (1995).  Outer hair cell length changes in an external electric field. II. The role of electrokinetic forces on the cell surface.  Journal of the Acoustical Society of America.  98(4).
  • Dutta A, Popel AS (1994).  Analysis of tissue diffusivity using mathematical models.  Advances in Experimental Medicine and Biology.  361.
  • Torres Filho IP, Cyrino FZ, Popel AS, Bouskela E, Johnson PC (1994).  Morphometric analysis of the anastomosing arteriolar network in cat sartorius muscle..  International journal of microcirculation, clinical and experimental / sponsored by the European Society for Microcirculation.  14(1-2).
  • Ong J, Enden G, Popel AS (1994).  Converging Three-Dimensional Stokes Flow of Two Fluids in a T-Type Bifurcation.  Journal of Fluid Mechanics.  270.
  • Popel AS, Johnson PC, Kameneva MV, Wild MA (1994).  Capacity for red blood cell aggregation is higher in athletic mammalian species than in sedentary species.  Journal of Applied Physiology.  77(4).
  • Enden G, Popel AS (1994).  A numerical study of plasma skimming in small vascular bifurcations.  Journal of Biomechanical Engineering.  116(1).
  • Ong JG, Enden G, Popel AS (1993).  Numerical simulation of blood flow in a venular bifurcation.  American Society of Mechanical Engineers, Bioengineering Division (Publication) BED.  26.
  • Popel AS, Enden G (1993).  An analytical solution for steady flow of a Quemada fluid in a circular tube.  Rheologica Acta.  32(4).
  • Gruben KG, Guerci AD, Halperin HR, Popel AS, Tsitlik JE (1993).  Sternal force-displacement relationship during cardiopulmonary resuscitation.  Journal of Biomechanical Engineering.  115(2).
  • Wang CH, Popel AS (1993).  Effect of red blood cell shape on oxygen transport in capillaries.  Mathematical Biosciences.  116(1).
  • Popel AS, Enden G, Ong J (1992).  Mechanics of blood flow in arteriolar and venular bifurcations.  American Society of Mechanical Engineers, Heat Transfer Division, (Publication) HTD.  231.
  • Tsitlik JE, Halperin HR, Popel AS, Shoukas AA, Yin FCP, Westerhof N (1992).  Modeling the circulation with three-terminal electrical networks containing special nonlinear capacitors.  Annals of Biomedical Engineering.  20(6).
  • Enden G, Popel AS (1992).  A numerical study of the shape of the surface separating flow into branches in microvascular bifurcations.  Journal of Biomechanical Engineering.  113(4).
  • Popel AS (1991).  Oxygen transport in resting skeletal muscle. Theory vs experiment.  Annals of Biomedical Engineering.  19(5).
  • Enden G, Popel AS (1991).  Computational analysis of flow division in vascular bifurcations at low Reynolds number.  American Society of Mechanical Engineers, Bioengineering Division (Publication) BED.  20.
  • Weerappuli DPV, Pittman RN, Popel AS (1990).  Effect of convection in capillaries on oxygen removal from arterioles in striated muscle.  Journal of Theoretical Biology.  147(2).
  • Torres Filho IP, Popel AS, Johnson PC, Cyrino FZ, Bouskela E (1990).  Shape and orientation of arterial loops in cat sartorius muscle..  International journal of microcirculation, clinical and experimental / sponsored by the European Society for Microcirculation.  9(3).
  • Bankman IN, Gruben KG, Halperin HR, Popel AS, Guerci AD, Tsitlik JE (1990).  Identification of Dynamic Mechanical Parameters of the Human Chest During Manual Cardiopulmonary Resuscitation.  IEEE Transactions on Biomedical Engineering.  37(2).
  • Popel AS (1989).  Theory of oxygen transport to tissue.  Critical Reviews in Biomedical Engineering.  17(3).
  • Sherman TF, Popel AS, Koller A, Johnson PC (1989).  The cost of departure from optimal radii in microvascular networks.  Journal of Theoretical Biology.  136(3).
  • Hudak ML, Jones MD, Popel AS, Koehler RC, Traystman RJ, Zeger SL (1989).  Hemodilution causes size-dependent constriction of pial arterioles in the cat.  American Journal of Physiology - Heart and Circulatory Physiology.  257(3).
  • Sharan M, Jones MD, Koehler RC, Traystman RJ, Popel AS (1989).  A compartmental model for oxygen transport in brain microcirculation.  Annals of Biomedical Engineering.  17(1).
  • Sharan M, Popel AS (1989).  Algorithm for computing oxygen dissociation curve with pH, PCO2, and CO in sheep blood.  Journal of Biomedical Engineering.  11(1).
  • Sharan M, Popel AS (1989).  A mathematical model of countercurrent exchange of oxygen between paired arterioles and venules.  Mathematical and Computer Modelling.  12(9).
  • Weerappuli DPV, Popel AS (1989).  A model of oxygen exchange between an arteriole or venule and the surrounding tissue.  Journal of Biomechanical Engineering.  111(1).
  • Popel AS, Pittman RN, Ellsworth ML, Weerappuli DP (1989).  Measurements of oxygen flux from arterioles imply high permeability of perfused tissue to oxygen..  Advances in Experimental Medicine and Biology.  248.
  • Popel AS, Pittman RN, Ellsworth ML (1989).  Rate of oxygen loss from arterioles is an order of magnitude higher than expected.  American Journal of Physiology - Heart and Circulatory Physiology.  256(3).
  • Popel AS, Torres Filho IP, Johnson PC, Bouskela E (1988).  A new scheme for hierarchical classification of anastomosing vessels..  International journal of microcirculation, clinical and experimental / sponsored by the European Society for Microcirculation.  7(2).
  • Sharan M, Popel AS (1988).  A mathematical model of countercurrent exchange of oxygen between paired arterioles and venules.  Mathematical Biosciences.  91(1).
  • Varela FE, Popel AS (1988).  Effect of intracapillary resistance to oxygen transport on the diffusional shunting between capillaries.  Journal of Biomedical Engineering.  10(5).
  • Ellsworth ML, Popel AS, Pittman RN (1988).  Assessment and impact of heterogeneities of convective oxygen transport parameters in capillaries of striated muscle: Experimental and theoretical.  Microvascular Research.  35(3).
  • Popel AS, Liu A, Dawant B, Koller A, Johnson PC (1988).  Distribution of vascular resistance in terminal arteriolar networks of cat sartorius muscle.  American Journal of Physiology - Heart and Circulatory Physiology.  254(6).
  • Popel AS (1987).  OXYGEN EXCHANGE IN MUSCLE AND BRAIN TISSUE..  American Society of Mechanical Engineers, Bioengineering Division (Publication) BED.  3.
  • Bankman IN, Gruben KG, Popel AS, Halperin HR, Thakor NV, Tsitlik JE (1987).  LEAST-MEAN-SQUARE PARAMETER IDENTIFICATION FOR CHEST COMPLIANCE MODELING IN CPR..  IEEE/Engineering in Medicine and Biology Society Annual Conference.
  • Koller A, Dawant B, Liu A, Popel AS, Johnson PC (1987).  Quantitative analysis of arteriolar network architecture in cat sartorius muscle.  American Journal of Physiology - Heart and Circulatory Physiology.  253(1).
  • Tsitlik JE, Halperin HR, Guerci AD, Dvorine LS, Popel AS, Siu CO, Yin FCP, Weisfeldt ML (1987).  Augmentation of pressure in a vessel indenting the surface of the lung.  Annals of Biomedical Engineering.  15(3-4).
  • Dvinsky AS, Popel AS (1987).  Motion of a rigid cylinder between parallel plates in Stokes flow. Part 1: motion in a quiescent fluid and sedimentation..  INT. J. NUMER. METHODS FLUIDS.  7(8 , Aug. 1987).
  • Dvinsky AS, Popel AS (1987).  Motion of a rigid cylinder between parallel plates in stokes flow. Part 2: Poiseuille and couette flow.  Computers and Fluids.  15(4).
  • Dvinsky AS, Popel AS (1987).  Motion of a rigid cylinder between parallel plates in stokes flow. Part 1: Motion in a quiescent fluid and sedimentation.  Computers and Fluids.  15(4).
  • Ellsworth ML, Liu A, Dawant B, Popel AS, Pittman RN (1987).  Analysis of vascular pattern and dimensions in arteriolar networks of the retractor muscle in young hamsters.  Microvascular Research.  34(2).
  • Dawant B, Levin M, Popel AS (1986).  Effect of dispersion of vessel diameters and lengths in stochastic networks. I. Modeling of microcirculatory flow.  Microvascular Research.  31(2).
  • Federspiel WJ, Popel AS (1986).  A theoretical analysis of the effect of the particulate nature of blood on oxygen release in capillaries.  Microvascular Research.  32(2).
  • Dvinsky AS, Popel AS (1986).  Numerical solution of two-dimensional stokes equations for flow with particles in a channel of arbitrary shape using boundary-conforming coordinates.  Journal of Computational Physics.  67(1).
  • Popel AS, Charny CK, Dvinsky AS (1986).  Effect of heterogeneous oxygen delivery on the oxygen distribution in skeletal muscle.  Mathematical Biosciences.  81(1).
  • Levin M, Dawant B, Popel AS (1986).  Effect of dispersion of vessel diameters and lengths in stochastic networks. II. Modeling of microvascular hematocrit distribution.  Microvascular Research.  31(2).
  • Levin M, Popel AS (1983).  MODELING OF BLOOD FLOW IN MICROVASCULAR NETWORKS..  American Society of Mechanical Engineers, Applied Mechanics Division, AMD.  56.
  • Dvinsky AS, Popel AS (1983).  TWO-DIMENSIONAL CREEPING FLOW AROUND A FREE RIGID PARTICLE IN A CHANNEL OF ARBITRARY SHAPE..  American Society of Mechanical Engineers, Applied Mechanics Division, AMD.  56.
  • Levin M, Popel AS (1983).  Modeling of blood flow in microvascular networks..  IN: 1983 ASME BIOMECHANICS SYMP., PRESENTED AT THE APPL. MECH., BIOENGNG., & FLUIDS ENGNG. CONF., (HOUSTON, U.S.A.: JUN. 19-2.  56 ) (FED-Vol.1).
  • Klitzman B, Popel AS, Duling BR (1983).  Oxygen transport in resting and contracting hamster cremaster muscles: Experimental and theoretical microvascular studies.  Microvascular Research.  25(1).
  • Popel AS (1982).  Oxygen diffusive shunts under conditions of heterogeneous oxygen delivery.  Journal of Theoretical Biology.  96(4).
  • Popel AS (1981).  Mathematical modeling of oxygen transport near a tissue surface: effect of the surface PO2.  Mathematical Biosciences.  55(3-4).
  • Popel AS (1980).  A model of pressure and flow distribution in branching networks.  Journal of Applied Mechanics, Transactions ASME.  47(2).
  • Popel AS (1980).  A model of pressure and flow distribution in branching networks..  TRANS. ASME J. APPL. MECH..  47(2 , Jun.1980).
  • Popel AS (1980).  Oxygen diffusion from capillary layers with concurrent flow.  Mathematical Biosciences.  50(3-4).
  • Popel AS (1979).  Diffusion in tissue slices with metabolism obeying Michaelis-Menten kinetics.  Journal of Theoretical Biology.  80(3).
  • Popel AS (1979).  EFFECT OF HETEROGENEITY OF CAPILLARY FLOW ON THE CAPILLARY HEMATOCRIT..  American Society of Mechanical Engineers, Applied Mechanics Division, AMD.  32.
  • Popel AS (1979).  Shielding of heat transfer from a boundary.  Journal of Heat Transfer.  101(3).
  • Popel AS, Gross JF (1979).  Analysis of oxygen diffusion from arteriolar networks.  American Journal of Physiology - Heart and Circulatory Physiology.  6(6).
  • Popel AS, Gross JF (1978).  Mass transfer in the entrance region of a circular tube.  International Journal of Heat and Mass Transfer.  21(8).
  • Popel AS (1978).  Analysis of capillary-tissue diffusion in multicapillary systems.  Mathematical Biosciences.  39(3-4).
  • Popel' AS (1976).  Motion of a spherical particle under the influence of osmotic forces.  Fluid Dynamics.  9(6).
  • Purinya BA, Popel' AS (1976).  Seminar on Biomechanics.  Polymer Mechanics.  10(4).
  • Popel AS, Regirer SA, Shadrina NK (1975).  Equations of kinetics for aggregation processes in suspensions. PMM vol.39, n{ring equal to}1, 1975, pp.130-143.  Journal of Applied Mathematics and Mechanics.  39(1).
  • Levtov VA, Popel' AS, Regirer SA, Shadrina NK (1974).  On an optical effect in blood flow.  Fluid Dynamics.  6(6).
  • Ivanova SV, Popel' AS (1974).  Motion of a drop in a viscous liquid under the action of an insoluble surface-active substance.  Fluid Dynamics.  9(2).
  • Popel AS, Regirer SA, Usick PI (1974).  A continuum model of blood flow..  Biorheology.  11(6).
  • Popel AS (1972).  Disk oscillations in a fluid with intrinsic angular momentum.  Fluid Dynamics.  5(1).
  • Popel AS (1972).  Some cases of two-dimensional duct flow of a fluid with internal rotation.  Fluid Dynamics.  4(6).
  • Popel AS (1972).  Hydrodynamics of suspensions.  Fluid Dynamics.  4(4).
  • Popel AS (1971).  Boundary layer on a rotating disk with account for the Hall effect.  Fluid Dynamics.  2(6).
Book Chapters
  • Popel AS, Pittman RN (2014).  The microcirculation physiome.  Biomechanics: Principles and Practices.
  • Mac Gabhann F, Stefanini MO, Popel AS (2012).  Simulating therapeutics using multiscale models of the VEGF receptor system in cancer.  Modeling Tumor Vasculature: Molecular, Cellular, and Tissue Level Aspects and Implications.  9781461400523.
  • Rivera CG, Chu LH, Bader JS, Popel AS (2012).  Applications of Network Bioinformatics to Cancer Angiogenesis.  Systems Biology in Cancer Research and Drug Discovery.  9789400748194.
  • Qutub AA, Gabhann FM, Karagiannis ED, Popel AS (2010).  In Silico Modeling of Angiogenesis at Multiple Scales: From Nanoscale to Organ System.  Multiscale Modeling of Particle Interactions: Applications in Biology and Nanotechnology.
  • Zhang J, Johnson PC, Popel AS (2010).  Microscopic hemodynamics and hemorheology with the immersed-boundary lattice-boltzmann method.  Computational Hydrodynamics of Capsules and Biological Cells.
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