Kuo, Scot C.

Associate Professor
Som Biomedical EngineeringBME Profile

Bldg G10
(410) 955-4536
skuo@jhu.edu

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About

Experience
  • 2013 - Present:  JOINT/SECONDARY FACULTY, SOM Cell Biology
  • 2006 - 2018:  Associate Professor, SOM Cell Biology

Publications

Journal Articles
  • Serbo JV, Kuo S, Lewis S, Lehmann M, Li J, Gracias DH, Romer LH (2016).  Patterning of Fibroblast and Matrix Anisotropy within 3D Confinement is Driven by the Cytoskeleton.  Advanced Healthcare Materials.  5(1).
  • Cockburn IA, Amino R, Kelemen RK, Kuo SC, Tse SW, Radtke A, Mac-Daniel L, Ganusov VV, Zavala F, Ménard R (2013).  In vivo imaging of CD8+T cell-mediated elimination of malaria liver stages.  Proceedings of the National Academy of Sciences of the United States of America.  110(22).
  • DeRose R, Pohlmeyer C, Umeda N, Ueno T, Nagano T, Kuo S, Inoue T (2012).  Spatio-temporal manipulation of small GTPase activity at subcellular level and on timescale of seconds in living cells..  Journal of visualized experiments : JoVE.  (61).
  • Yamanaka S, Campbell NR, An F, Kuo SC, Potter JJ, Mezey E, Maitra A, Selaru FM (2012).  Coordinated effects of microRNA-494 induce G2/M arrest in human cholangiocarcinoma.  Cell Cycle.  11(14).
  • Fisher CI, Kuo SC (2009).  Filament rigidity causes F-actin depletion from nonbinding surfaces.  Proceedings of the National Academy of Sciences of the United States of America.  106(1).
  • Reichl EM, Ren Y, Morphew MK, Delannoy M, Effler JC, Girard KD, Divi S, Iglesias PA, Kuo SC, Robinson DN (2008).  Interactions between Myosin and Actin Crosslinkers Control Cytokinesis Contractility Dynamics and Mechanics.  Current Biology.  18(7).
  • Girard KD, Kuo SC, Robinson DH (2006).  Dictyostelium myosin II mechanochemistry promotes active behavior of the cortex on long time scales.  Proceedings of the National Academy of Sciences of the United States of America.  103(7).
  • Girard KD, Chaney C, Delannoy M, Kuo SC, Robinson DN (2004).  Dynacortin contributes to cortical viscoelasticity and helps define the shape changes of cytokinesis.  EMBO Journal.  23(7).
  • McGrath JL, Eungdamrong NJ, Fisher CI, Peng F, Mahadevan L, Mitchison TJ, Kuo SC (2003).  The force-velocity relationship for the actin-based motility of Listeria monocytogenes.  Current Biology.  13(4).
  • Kuo SC (2001).  Using optics to measure biological forces and mechanics.  Traffic.  2(11).
  • Boustany NN, Kuo SC, Thakor NV (2001).  Optical scatter imaging: Subcellular morphometry in situ with Fourier filtering.  Optics Letters.  26(14).
  • Boustany NN, Thakor NV, Kuo SC (2001).  Optical scatter imaging for in situ subcellular morphometry.  Optics and Photonics News.  12(12).
  • Boustany N, Thompson T, Thakor N, Kuo S (2000).  Dynamic observation of organelle morphology during calcium cell injury with ratiometric dark-field microscopy.  Annals of Biomedical Engineering.  28(SUPPL. 1).
  • Kuo S, McGrath J (2000).  Molecular resolution of listeria monocytogenes motion during actin-based motility.  Annals of Biomedical Engineering.  28(SUPPL. 1).
  • McGrath J, Hartwig J, Kuo S (2000).  Mechanics of F-actin microenvironments probed by Brownian particles.  Annals of Biomedical Engineering.  28(SUPPL. 1).
  • Kuo SC, McGrath JL (2000).  Steps and fluctuations of Listeria monocytogenes during actin-based motility.  Nature.  407(6807).
  • Yamada S, Wirtz D, Kuo SC (2000).  Mechanics of living cells measured by laser tracking microrheology.  Biophysical Journal.  78(4).
  • McGrath JL, Hartwig JH, Kuo SC (2000).  The mechanics of F-actin microenvironments depend on the chemistry of probing surfaces.  Biophysical Journal.  79(6).
  • Roy K, Chu W, McGrath J, Kuo SC, Huang SK, Leong KW (1999).  Nanoparticle mediated oral gene delivery for DNA vaccination.  Proceedings of the Controlled Release Society.  (26).
  • Gheber L, Kuo SC, Hoyt MA (1999).  Motile properties of the kinesin-related Cin8p spindle motor extracted from Saccharomyces cerevisiae cells.  Journal of Biological Chemistry.  274(14).
  • Palmer A, Mason TG, Xu J, Kuo SC, Wirtz D (1999).  Diffusing wave spectroscopy microrheology of actin filament networks.  Biophysical Journal.  76(2).
  • Kuo SC (1998).  A simple assay for local heating by optical tweezers.  Methods in Cell Biology.  (55).
  • Mason TG, Ganesan K, Van Zanten JH, Wirtz D, Kuo SC (1997).  Particle tracking microrheology of complex fluids.  Physical Review Letters.  79(17).
  • Kuo SC (1997).  Chapter 3 A Simple Assay for Local Heating by Optical Tweezers.  Methods in Cell Biology.  55(C).
  • Kuo SC (1995).  Optical Tweezers: A Practical Guide.  Microscopy and Microanalysis.  1(2).
  • Kuo SC, Ramanathan K, Sorg B (1995).  Single kinesin molecules stressed with optical tweezers.  Biophysical Journal.  68(4 SUPPL.).
  • Kuo SC, Sheetz MP (1993).  Force of single kinesin molecules measured with optical tweezers.  Science.  260(5105).
  • Sheetz MP, Kuo SC (1993).  Tracking Nanometer Movements of Single Motor Molecules.  Methods in Cell Biology.  39(C).
  • Wang XF, Kuo SC, Lemasters JJ, Herman B (1992).  Measurements of plasma membrane architecture during hypoxia using multiple fluorescent spectroscopic techniques.  Proceedings of SPIE - The International Society for Optical Engineering.  1640.
  • Kuo SC, Sheetz MP (1992).  Optical tweezers in cell biology.  Trends in Cell Biology.  2(4).
  • Kuo SC, Gelles J, Steuer E, Sheetz MP (1991).  A model for kinesin movement from nanometer-level movements of kinesin and cytoplasmic dynein and force measurements.  Journal of Cell Science.  98(SUPPL. 14).
  • Kucik DF, Kuo SC, Elson EL, Sheetz MP (1991).  Preferential attachment of membrane glycoproteins to the cytoskeleton at the leading edge of lamella.  Journal of Cell Biology.  114(5).
  • Edidin M, Kuo SC, Sheetz MP (1991).  Lateral movements of membrane glycoproteins restricted by dynamic cytoplasmic barriers.  Science.  254(5036).
  • Kuo SC, Koshland DE (1989).  Multiple kinetic states for the flagellar motor switch.  Journal of Bacteriology.  171(11).
  • Kuo SC, Koshland DE (1987).  Roles of cheY and cheZ gene products in controlling flagellar rotation in bacterial chemotaxis of Escherichia coli.  Journal of Bacteriology.  169(3).
  • Kup SC, Koshland DE (1986).  Sequence of the flaA (cheC) locus of Escherichia coli and discovery of a new gene.  Journal of Bacteriology.  166(3).
  • Kuo SC, Koshland DE (1985).  The E. coli cheC gene and a new adjacent flagellar gene: Sequence and behavioral data.  Federation Proceedings.  44(5).
  • Macara IG, Kuo S, Cantley LC (1983).  Evidence that inhibitors of anion exchange induce a transmembrane conformational change in band 3..  Journal of Biological Chemistry.  258(3).
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