Iglesias, Pablo A.

Professor
Electrical And Computer Engineering
http://www.ece.jhu.edu/cscl/

Barton Hall 226
(410) 516-6026
pi@jhu.edu

Jump to:

News

About

Education
  • Ph.D., CAMBRIDGE UNIVERSITY
  • Ph.D. 1991, Cambridge University
Experience
  • 2013 - Present:  Joint, SOM Cell Biology
  • 2012 - 2012:  NIH Study Section: 2013/01 MABS meeting, NIH
  • 2008 - Present:  Director, Unspecified
  • 2006 - 2011:  Chair, NIH BRT
  • 2004 - 2007:  Co-Director, Institute for Multi-Scale Modeling of Biological Interactions, Johns Hopkins University
  • 2004 - 2004:  Co-Chair, GENSIPS
  • 2003 - Present:  Joint, SOM Biomedical Engineering
  • 2002 - 2002:  Chair, Conference on Decision and Control
  • 2002 - 2002:  Chair, advisory committee, ECE Department
  • 2001 - 2001:  Co-Chair, Conference on Information Sciences and Systems
  • 1995 - 1995:  Co-Chair, Conference on Information Sciences and Systems
  • 1994 - 1994:  Chair, American Control Conference
Research Areas
  • Regulatory mechanisms that control cell division
  • The sensing and actuation that enable cells to maintain lipid homeostasis
  • Understanding how cells interpret directional cues to guide cell motion
  • Use of control and information theory to study biological signal transduction pathways
Awards
  • 2018:  Semiplenary speaker: European Control Conference - Cambridge - UK - September 2003
  • 2018:  IEEE Senior Member
  • 2017:  Fellow
  • 2012:  Edward J. Schaefer Chair in Electrical Engineering
  • 2012:  Visiting Scientist Position at Max-Planck Institute for the Physics of Complex Systems
  • 2010:  NASA Glenn Research Center Certificate of Recognition for mentorship in the NASA Motivating Undergraduates in Science and Technology (MUST) project
  • 2009:  Distinguished Lecturer: Integrative Biosystems Institute at Georgia Tech
  • 2006:  Distinguished lecturer - IEEE Control Systems Society
  • 2006:  Named a Science Spectrum Trailblazer by Science Spectrum Magazine
  • 1997:  George E. Owen Teaching Award - Johns Hopkins University
  • 1992:  George E. Ives Best Paper Award for the Journal of Imaging Technology - Society for Imaging and Technology
  • 1990:  Best Young Author Prize Finalist - IFAC World Congress - Tallinn USSR
Presentations
  • "Controlling the migratory mode of cells by altering the set point of an excitable network", How to get from A to B: Transitions in Biology.  Princeton New Jersey, United States of America (the).  December 13, 2017
  • "Set point control, excitable systems and cell migration", Control of Cellular and Molecular Systems.  Columbus Ohio, United States of America (the).  October 4, 2017
  • "The set point of an excitable system determines the migratory mode of cells", QCB Workshop on Cells as Dynamical Systems.  San Francisco California, United States of America (the).  May 22, 2017
  • "Excitable and Other Dynamic Behaviors in Migrating Cells", CMS Colloquium.  Pasadena California, United States of America (the).  May 8, 2017
  • "Excitability and other dynamic behaviors regulating motility", Department of Electrical & Computer Eng,.  May 14, 2016
  • "Excitability and other dynamic behaviors regulating motility", Institute of Nano-Biotechnology.  Baltimore, MD.  May 3, 2016
  • Workshop on Control and Observability of Network Dynamics.  Columbus, OH.  April 11, 2016
  • "INFORMATION-THEORETIC CHARACTERIZATION OF CELL SIGNALING NETWORKS", 2015 MBMC Workshop: Communications, Inference, and Computing In Molecular and Biological Systems.  Los Angeles, CS.  December 3, 2015
  • "Excitability and other dynamic behaviors regulating motility", Workshop on Biological Systems and Networks.  Minneapolis, MN.  November 16, 2015
  • "Biased excitable networks: HOW cells direct Motion in response to gradients", Colloquium.  Laurel, MD.  October 2, 2015
  • "Biological Applications of Control", Workshop on Biological applications of Control.  Tel Aviv, Israel.  June 1, 2015
  • "Biased excitable networks and directed cell migration", Random Walks and Nonlinear Dynamics in the Life of Single Cells.  Dresden, Germany.  May 18, 2015
  • "Biased excitable networks and directed cell migration", SY-BIO Workshop.  Dallas, TX.  March 25, 2015
  • "A modular view of directed cell migration", Gordon Research Conference on Gradient Sensing and Directed Cell Migration.  Galveston, TX.  January 25, 2015
  • "Uncovering the cell's guidance mechanism through computational biology", 10th Annual Engineering Science Education Conference.  Toronto, ON, Canada.  January 23, 2015
  • "Evolutionarily Conserved Coupling of Adaptive and Excitable Networks Mediates Eukaryotic Chemotaxis", Biophysical Society Annual Meeting.  Baltimore, MD.  January 1, 2015
  • "Kinetics of Mechanoresponse in the Mammalian Actin Cytoskeleton", Biophysical Society Annual Meeting.  Baltimore, MD.  January 1, 2015
  • "Nucleocytoplasmic Shuttling of a Gata-Family Transcription Factor Functions as a Development Timer", Biophysical Society Annual Meeting.  Baltimore, MD.  January 1, 2015
  • Signaling Across Scales.  Ann Arbor.  March 11, 2014
  • "Novel modeling approaches to cell motility", March meeting of the APS.  Denver.  March 7, 2014

Publications

Journal Articles
  • Devreotes PN, Bhattacharya S, Edwards M, Iglesias PA, Lampert T, Miao Y (2017).  Excitable signal transduction networks in directed cell migration.  Annual Review of Cell and Developmental Biology.  33.
  • Singh P, Ramachandran SK, Zhu J, Kim BC, Biswas D, Ha T, Iglesias PA, Li R (2017).  Sphingolipids facilitate age asymmetry of membrane proteins in dividing yeast cells.  Molecular Biology of the Cell.  28(20).
  • Bhattacharya S, Iglesias PA (2017).  The triggering, curving and stopping of excitable waves during cell migration.  2017 51st Annual Conference on Information Sciences and Systems, CISS 2017.
  • Miao Y, Bhattacharya S, Edwards M, Cai H, Inoue T, Iglesias PA, Devreotes PN (2017).  Altering the threshold of an excitable signal transduction network changes cell migratory modes.  Nature Cell Biology.  (4).
  • Artemenko Y, Axiotakis L, Borleis J, Iglesias PA, Devreotes PN (2016).  Chemical and mechanical stimuli act on common signal transduction and cytoskeletal networks.  Proceedings of the National Academy of Sciences of the United States of America.  113(47).
  • Zeituni EM, Wilson MH, Zheng X, Iglesias PA, Sepanski MA, Siddiqi MA, Anderson JL, Zheng Y, Farber SA (2016).  Endoplasmic reticulum lipid flux influences enterocyte nuclear morphology and lipid-dependent transcriptional responses.  Journal of Biological Chemistry.  291(45).
  • Iglesias P, Bhattacharya S (2016).  Modeling excitable dynamics of chemotactic networks.  Methods in Molecular Biology.  1407.  397-415.
  • Iglesias P (2016).  The use of rate distortion theory to evaluate biological signaling pathways.  IEEE Transactions on Molecular, Biological and Multi-Scale Communications.  2(1).  31-39.
  • Iglesias PA (2016).  The Use of Rate Distortion Theory to Evaluate Biological Signaling Pathways.  IEEE Transactions on Molecular, Biological, and Multi-Scale Communications.  2(1).
  • Srivastava V, Iglesias P, Robinson DN (2016).  Cytokinesis: Robust cell shape regulation.  Seminars in Cell & Developmental Biology.  53.  39-44.
  • Bhattacharya , Bhattacharya S (2016).  The regulation of cell motility through an excitable network.
  • Schiffhauer ES, Luo T, Mohan K, Srivastava V, Qian X, Griffis ER, Iglesias PA, Robinson DN (2016).  Mechanoaccumulative Elements of the Mammalian Actin Cytoskeleton.  Current Biology.  26(11).
  • Bhattacharya S, Iglesias PA (2016).  The Regulation of Cell Motility Through an Excitable Network.  IFAC-PapersOnLine.  49(26).
  • Mohan K, Luo T, Robinson DN, Iglesias PA (2015).  Cell shape regulation through mechanosensory feedback control.  Journal of the Royal Society Interface.  12(109).
  • Swaney KF, Borleis J, Iglesias PA, Devreotes PN (2015).  Novel protein Callipygian defines the back of migrating cells.  Proceedings of the National Academy of Sciences of the United States of America.  112(29).
  • Srivastava V, Iglesias PA, Robinson DN (2015).  Cytokinesis: Robust cell shape regulation.  Seminars in Cell and Developmental Biology.
  • Cai H, Katoh-Kurasawa M, Muramoto T, Santhanam B, Long Y, Li L, Ueda M, Iglesias P, Shaulsky G, Devreotes PN (2015).  Nucleocytoplasmic Shuttling of a Gata-Family Transcription Factor Functions as a Development Timer.  Biophysical Journal.  108(2).  463a.
  • Schiffhauer E, Luo T, Qian X, Mohan K, Iglesias P, Robinson D (2015).  Kinetics of Mechanoresponse in the Mammalian Actin Cytoskeleton.  Biophysical Journal.  108(2).  180a.
  • Swaney KF, Borleis J, Iglesias P, Devreotes PN (2015).  Novel protein Callipygian defines the back of migrating cells.  Proceedings of the National Academy of Sciences.  112(29).  E3845-E3854.
  • Huang C, Tang M, Wang M, Shi C, Iglesias P, Devreotes PN (2015).  Evolutionarily Conserved Coupling of Adaptive and Excitable Networks Mediates Eukaryotic Chemotaxis.  Biophysical Journal.  108(2).  456a.
  • Iglesias P, Shi C (2014).  Comparison of adaptation motifs: temporal, stochastic and spatial responses.  IET Systems Biology.  8(6).  268-281.
  • Huang C, Iglesias P (2014).  Cell memory and adaptation in chemotaxis.  Proceedings of the National Academy of Sciences.  111(43).  15287-15288.
  • Tang M, Wang M, Shi C, Iglesias P, Devreotes PN, Huang C (2014).  Evolutionarily conserved coupling of adaptive and excitable networks mediates eukaryotic chemotaxis.  Nature Communications.  5.  Article: 5175.
  • Wang M, Artemenko Y, Cai W, Iglesias P, Devreotes PN (2014).  The Directional Response of Chemotactic Cells Depends on a Balance between Cytoskeletal Architecture and the External Gradient.  Cell Reports.  9(3).  1110-1121.
  • Shi C, Channels WE, Zheng Y, Iglesias P (2014).  A computational model for the formation of lamin-B mitotic spindle envelope and matrix.  Interface Focus.  4(3).  20130063.
  • Cai H, Katoh-Kurasawa M, Muramoto T, Santhanam B, Long Y, Li L, Ueda M, Iglesias P, Shaulsky G, Devreotes PN (2014).  Nucleocytoplasmic Shuttling of a GATA Transcription Factor Functions as a Development Timer.  Science.  343(6177).  1249531.
  • Robinson DN, Luo T, Mohan K, Srivastava V, Ren Y, Iglesias P (2014).  Molecular Mechanisms of Contractility-Based Cellular Mechanosensing.  Biophysical Journal.  106(2).  357a.
  • Cai H, Katoh-Kurasawa M, Muramoto T, Santhanam B, Long Y, Li L, Ueda M, Iglesias PA, Shaulsky G, Devreotes PN (2014).  Nucleocytoplasmic shuttling of a GATA transcription factor functions as a development timer.  Science.  343(6177).
  • Tang M, Wang M, Shi C, Iglesias PA, Devreotes PN, Huang CH (2014).  Evolutionarily conserved coupling of adaptive and excitable networks mediates eukaryotic chemotaxis.  Nature Communications.  5.
  • Shi C, Channels WE, Zheng Y, Iglesias PA (2014).  A computational model for the formation of lamin-B mitotic spindle envelope and matrix.  Interface Focus.  4(3).
  • Mohan K, Luo T, Robinson DN, Iglesias P (2014).  Computational Model for Cell Shape Regulation through Mechanosensing and Mechanical Feedback.  Biophysical Journal.  106(2).  378a.
  • Wang MJ, Artemenko Y, Cai WJ, Iglesias PA, Devreotes PN (2014).  The directional response of chemotactic cells depends on a balance between cytoskeletal architecture and the external gradient.  Cell Reports.  9(3).
  • Iglesias PA, Shi C (2014).  Comparison of adaptation motifs: Temporal, stochastic and spatial responses.  IET Systems Biology.  8(6).
  • Huang CH, Tang M, Shi C, Iglesias PA, Devreotes PN (2013).  An excitable signal integrator couples to an idling cytoskeletal oscillator to drive cell migration.  Nature Cell Biology.  15(11).
  • Luo T, Mohan K, Iglesias PA, Robinson DN (2013).  Molecular mechanisms of cellular mechanosensing.  Nature Materials.  12(11).
  • Shi C, Iglesias PA (2013).  Excitable behavior in amoeboid chemotaxis.  Wiley Interdisciplinary Reviews: Systems Biology and Medicine.  5(5).
  • Shi C, Huang CH, Devreotes PN, Iglesias PA (2013).  Interaction of Motility, Directional Sensing, and Polarity Modules Recreates the Behaviors of Chemotaxing Cells.  PLoS Computational Biology.  9(7).
  • Zheng Y, Iglesias PA (2013).  Nucleating new branches from old.  Cell.  152(4).
  • Zheng Y, Iglesias P (2013).  Nucleating New Branches from Old.  Cell.  152(4).  669-670.
  • Luo T, Mohan K, Iglesias P, Robinson DN (2013).  The Molecular Landscape of Mechanosensing by the Cell Cortex.  Biophysical Journal.  104.  476.
  • Shi C, Iglesias P (2013).  Excitable behavior in amoeboid chemotaxis.  Wiley Interdisciplinary Reviews: Systems Biology and Medicine.  5(5).  631-642.
  • Huang C, Tang M, Shi C, Iglesias P, Devreotes PN (2013).  An excitable signal integrator couples to an idling cytoskeletal oscillator to drive cell migration.  Nature cell biology.
  • Iglesias P (2013).  Systems Biology: The Role of Engineering in the Reverse Engineering of Biological Signaling.  Cells.  2(2).  393-413.
  • Shi C, Huang C, Devreotes PN, Iglesias P (2013).  Interaction of motility, directional sensing, and polarity modules recreates the behaviors of chemotaxing cells.  PLoS computational biology.  9(7).  e1003122.
  • Robinson DN, Iglesias PA (2012).  Bringing the physical sciences into your cell biology research.  Molecular Biology of the Cell.  23(21).
  • Porter JR, Lee CYS, Espenshade PJ, Iglesias PA (2012).  Regulation of SREBP during hypoxia requires Ofd1-mediated control of both DNA binding and degradation.  Molecular Biology of the Cell.  23(18).
  • Mohan K, Iglesias PA, Robinson DN (2012).  Separation anxiety: Stress, tension and cytokinesis.  Experimental Cell Research.  318(12).
  • Porter JR, Burg JS, Espenshade PJ, Iglesias PA (2012).  Identifying a static nonlinear structure in a biological system using noisy, sparse data.  Journal of Theoretical Biology.  300.
  • Kee YS, Ren Y, Dorfman D, Iijima M, Firtel R, Iglesias PA, Robinson DN (2012).  A mechanosensory system governs myosin II accumulation in dividing cells.  Molecular Biology of the Cell.  23(8).
  • Iglesias PA, Devreotes PN (2012).  Biased excitable networks: How cells direct motion in response to gradients.  Current Opinion in Cell Biology.  24(2).
  • Poirier CC, Ng WP, Robinson DN, Iglesias PA (2012).  Deconvolution of the cellular force-generating subsystems that govern cytokinesis furrow ingression.  PLoS Computational Biology.  8(4).
  • Porter JR, Andrews BW, Iglesias PA (2012).  A framework for designing and analyzing binary decision-making strategies in cellular systems..  Integrative biology : quantitative biosciences from nano to macro.  4(3).
  • Iglesias PA (2012).  Chemoattractant signaling in Dictyostelium: Adaptation and amplification.  Science Signaling.  5(213).
  • Iglesias PA (2012).  A systems biology view of adaptation in sensory mechanisms.  Advances in Experimental Medicine and Biology.  736.
  • Luo T, Mohan K, Srivastava V, Ren Y, Iglesias PA, Robinson DN (2012).  Understanding the cooperative interaction between myosin II and actin cross-linkers mediated by actin filaments during mechanosensation.  Biophysical Journal.  102(2).
  • Porter JR, Lee CS, Espenshade PJ, Iglesias P (2012).  Regulation of SREBP during hypoxia requires Ofd1-mediated control of both DNA bindingand degradation.  Molecular biology of the cell.  23(18).  3764-3774.
  • Seir Kee Y, Ren Y, Dorfman D, Iijima M, Firtel R, Iglesias P, Robinson D (2012).  A Mechanosensory System Governs Myosin II Cleavage Furrow Accumulation.  Biophysical Journal.  102(3).  349a.
  • Porter JR, Burg JS, Espenshade PJ, Iglesias P (2012).  Identifying a static nonlinear structure in a biological system using noisy, sparse data.  Journal of theoretical biology.  300.  232-241.
  • Poirier CC, Ng WP, Robinson DN, Iglesias P (2012).  Deconvolution of the cellular force-generating subsystems that govern cytokinesis furrow ingression.  PLoS computational biology.  8(4).  e1002467.
  • Luo T, Mohan K, Srivastava V, Ren Y, Iglesias P, Robinson DN (2012).  Understanding the cooperative interaction between myosin II and actin cross-linkers mediated by actin filaments during mechanosensation.  Biophysical journal.  102(2).  238-247.
  • Iglesias P (2012).  Chemoattractant signaling in dictyostelium: adaptation and amplification.  Science signaling.  5(213).  pe8.
  • Kee Y, Ren Y, Dorfman D, Iijima M, Firtel R, Iglesias P, Robinson DN (2012).  A mechanosensory system governs myosin II accumulation in dividing cells.  Molecular biology of the cell.  23(8).  1510-1523.
  • Iglesias P, Devreotes PN (2012).  Biased excitable networks: how cells direct motion in response to gradients.  Current Opinion in Cell Biology.  24(2).  245-253.
  • Mohan K, Iglesias P, Robinson DN (2012).  Separation anxiety: Stress, tension and cytokinesis.  Experimental Cell Research.  318(12).  1428-1434.
  • Porter JR, Andrews BW, Iglesias P (2012).  A framework for designing and analyzing binary decision-making strategies in cellular systems.  Integrative Biology.  4(3).  310-317.
  • Robinson DN, Iglesias P (2012).  Bringing the physical sciences into your cell biology research.  Molecular biology of the cell.  23(21).  4167-4170.
  • McDole K, Xiong Y, Iglesias PA, Zheng Y (2011).  Lineage mapping the pre-implantation mouse embryo by two-photon microscopy, new insights into the segregation of cell fates.  Developmental Biology.  355(2).
  • Shi C, Channels WE, Zheng Y, Iglesias PA (2011).  A continuum computational model of mitotic matrix formation.  2011 45th Annual Conference on Information Sciences and Systems, CISS 2011.
  • Porter JR, Iglesias PA, Burg JS, Espenshade PJ (2011).  Overcoming data limitations to identify a static nonlinearity in a biological signaling cascade.  2011 45th Annual Conference on Information Sciences and Systems, CISS 2011.
  • De Keijzer S, Galloway J, Harms GS, Devreotes PN, Iglesias PA (2011).  Disrupting microtubule network immobilizes amoeboid chemotactic receptor in the plasma membrane.  Biochimica et Biophysica Acta - Biomembranes.  1808(6).
  • Xiong Y, Huang C, Iglesias P, Devreotes PN (2011).  A LEGI-Biased Excitable Network Controls Temporal and Spatial Responses to Chemoattractants.  Biophysical Journal.  100(3 Supplement 1).
  • Kee YS, Firtel R, Iglesias P, Robinson D (2011).  Mechanosensing Directs Mitotic Signaling Proteins to Sites of High Mechanical Stress to Regulate Cytokinesis Through a Feedback Control System.  Biophysical Journal.  100(3).  444a-445a.
  • Poirier CC, Ng W, Robinson DN, Iglesias P (2011).  A Dynamic Model of Furrow Ingression during Cytokinesis.  Biophysical Journal.  100(3).  610a.
  • Poirier CC, Zheng Y, Iglesias P (2011).  Enclosing, Deformable Membrane Aids in Focusing and Stabilizing the Mitotic Spindle.  Biophysical Journal.  100(3).  450a.
  • McDole K, Xiong Y, Iglesias P, Zheng Y (2011).  Lineage mapping the pre-implantation mouse embryo by two-photon microscopy, new insights into the segregation of cell fates.  Developmental biology.  355(2).  239-249.
  • Porter JR, Burg JS, Espenshade PJ, Iglesias PA (2010).  Ergosterol regulates sterol regulatory element binding protein (SREBP) cleavage in fission yeast.  Journal of Biological Chemistry.  285(52).
  • Poirier CC, Zheng Y, Iglesias PA (2010).  Mitotic membrane helps to focus and stabilize the mitotic spindle.  Biophysical Journal.  99(10).
  • Zhou Q, Kee YS, Poirier CC, Jelinek C, Osborne J, Divi S, Surcel A, Will ME, Eggert US, Müller-Taubenberger A, Iglesias PA, Cotter RJ, Robinson DN (2010).  14-3-3 coordinates microtubules, rac, and myosin II to control cell mechanics and cytokinesis.  Current Biology.  20(21).
  • Goodman B, Channels W, Qiu M, Iglesias P, Yang G, Zheng Y (2010).  Lamin B counteracts the kinesin Eg5 to restrain spindle pole separation during spindle assembly.  Journal of Biological Chemistry.  285(45).
  • Xiong Y, Iglesias PA (2010).  Tools for analyzing cell shape changes during chemotaxis.  Integrative Biology.  2(11-12).
  • Xiong Y, Huang CH, Iglesias PA, Devreotes PN (2010).  Cells navigate with a local-excitation, global-inhibition-biased excitable network.  Proceedings of the National Academy of Sciences of the United States of America.  107(40).
  • Xiong Y, Kabacoff C, Franca-Koh J, Devreotes PN, Robinson DN, Iglesias PA (2010).  Automated characterization of cell shape changes during amoeboid motility by skeletonization.  BMC Systems Biology.  4.
  • Xiong Y, Kabacoff C, Franca-Koh J, Devreotes PN, Robinson DN, Iglesias P (2010).  Automated characterization of cell shape changes during amoeboid motility by skeletonization.  BMC systems biology.  4(1).  33.
  • Goodman B, Channels W, Qiu M, Iglesias P, Yang G, Zheng Y (2010).  Lamin B counteracts the kinesin Eg5 to restrain spindle pole separation during spindle assembly.  Journal of Biological Chemistry.  285(45).  35238-35244.
  • Porter JR, Burg JS, Espenshade PJ, Iglesias P (2010).  Ergosterol regulates sterol regulatory element binding protein (SREBP) cleavage in fission yeast.  Journal of Biological Chemistry.  285(52).  41051-41061.
  • Poirier CC, Zheng Y, Iglesias P (2010).  Mitotic membrane helps to focus and stabilize the mitotic spindle.  Biophysical journal.  99(10).  3182-3190.
  • Xiong Y, Iglesias P (2010).  Tools for analyzing cell shape changes during chemotaxis.  Integrative Biology.  2(11-12).  561-567.
  • Ingalls BP, Iglesias P (2010).  A Primer on Control Engineering.  Control Theory and Systems Biology.  1-28.
  • Xiong Y, Huang C, Iglesias P, Devreotes PN (2010).  Cells navigate with a local-excitation, global-inhibition-biased excitable network.  Proceedings of the National Academy of Sciences.  107(40).  17079-17086.
  • Kee YS, Firtel R, Iglesias P, Robinson D (2010).  Myosin II is an Active Stress Sensor at the Core of a Cell Division Control System.  Biophysical Journal.  98(3).  161a-162a.
  • Channels WE, Iglesias P (2010).  Simulating Filament Dynamics in Cellular Systems.  Elements of Computational Systems Biology.  141-162.
  • Yang L, Iglesias PA (2009).  Modeling spatial and temporal dynamics of chemotactic networks..  Methods in molecular biology (Clifton, N.J.).  571.
  • Xiong Y, Iglesias PA (2009).  Automated characterization of amoeboid motility.  Proceedings - 43rd Annual Conference on Information Sciences and Systems, CISS 2009.
  • Ghaemi R, Sun J, Iglesias PA, Del Vecchio D (2009).  A method for determining the robustness of bio-molecular oscillator models.  BMC Systems Biology.  3.
  • Ren Y, Effler JC, Norstrom M, Luo T, Firtel RA, Iglesias PA, Rock RS, Robinson DN (2009).  Mechanosensing through Cooperative Interactions between Myosin II and the Actin Crosslinker Cortexillin I.  Current Biology.  19(17).
  • Iglesias PA (2009).  Spatial regulation of PI3K signaling during chemotaxis.  Wiley Interdisciplinary Reviews: Systems Biology and Medicine.  1(2).
  • Ren Y, Effler JC, Norstrom M, Luo T, Firtel RA, Iglesias P, Rock RS, Robinson DN (2009).  Mechanosensing through cooperative interactions between myosin II and the actin crosslinker cortexillin I.  Current Biology.  19(17).  1421-1428.
  • Iglesias P (2009).  Spatial regulation of PI3K signaling during chemotaxis.  Wiley Interdisciplinary Reviews: Systems Biology and Medicine.  1(2).  247-253.
  • Ghaemi R, Sun J, Iglesias P, Del Vecchio D (2009).  A method for determining the robustness of bio-molecular oscillator models.  BMC systems biology.  3(1).  95.
  • Andrews B, Sontag ED, Iglesias PA (2008).  An approximate internal model principle: Applications to nonlinear models of biological systems.  IFAC Proceedings Volumes (IFAC-PapersOnline).  17(1 PART 1).
  • Arkowitz RA, Iglesias PA (2008).  Basic principles of polarity establishment and maintenance. Conference on Mechanisms of Cell Polarity.  EMBO Reports.  9(9).
  • Tang L, Franca-Koh J, Xiong Y, Chen MY, Long Y, Bickford RM, Knecht DA, Iglesias PA, Devreotes PN (2008).  tsunami, the Dictyostelium homolog of the Fused kinase, is required for polarization and chemotaxis.  Genes and Development.  22(16).
  • Yang L, Effler JC, Kutscher BL, Sullivan SE, Robinson DN, Iglesias PA (2008).  Modeling cellular deformations using the level set formalism.  BMC Systems Biology.  2.
  • Kamimura Y, Xiong Y, Iglesias PA, Hoeller O, Bolourani P, Devreotes PN (2008).  PIP3-Independent Activation of TorC2 and PKB at the Cell's Leading Edge Mediates Chemotaxis.  Current Biology.  18(14).
  • Reichl EM, Ren Y, Morphew MK, Delannoy M, Effler JC, Girard KD, Divi S, Iglesias PA, Kuo SC, Robinson DN (2008).  Interactions between Myosin and Actin Crosslinkers Control Cytokinesis Contractility Dynamics and Mechanics.  Current Biology.  18(7).
  • Channels WE, Nédélec FJ, Zheng Y, Iglesias PA (2008).  Spatial regulation improves antiparallel microtubule overlap during mitotic spindle assembly.  Biophysical Journal.  94(7).
  • Iglesias PA, Devreotes PN (2008).  Navigating through models of chemotaxis.  Current Opinion in Cell Biology.  20(1).
  • Krishnan J, Iglesias PA (2008).  Systems analysis of regulatory processes underlying eukaryotic gradient perception.  IEEE Transactions on Automatic Control.  53(SPECIAL ISSUE).
  • Reichl EM, Ren Y, Morphew MK, Delannoy M, Effler JC, Girard KD, Divi S, Iglesias P, Kuo SC, Robinson DN (2008).  Interactions between myosin and actin crosslinkers control cytokinesis contractility dynamics and mechanics.  Current Biology.  18(7).  471-480.
  • Channels WE, Nédélec FJ, Zheng Y, Iglesias P (2008).  Spatial regulation improves antiparallel microtubule overlap during mitotic spindle assembly.  Biophysical journal.  94(7).  2598-2609.
  • Andrews B, Sontag ED, Iglesias P (2008).  An approximate internal model principle: Applications to nonlinear models of biological systems.  Proceedings of the 17th IFAC World Congress.  6-11.
  • Krishnan J, Iglesias P (2008).  Systems analysis of regulatory processes underlying eukaryotic gradient perception.  Automatic Control, IEEE Transactions on.  53(Special Issue).  126-138.
  • Kamimura Y, Xiong Y, Iglesias P, Hoeller O, Bolourani P, Devreotes PN (2008).  PIP< sub> 3-Independent Activation of TorC2 and PKB at the Cell's Leading Edge Mediates Chemotaxis.  Current Biology.  18(14).  1034-1043.
  • Yang L, Effler JC, Kutscher BL, Sullivan SE, Robinson DN, Iglesias P (2008).  Modeling cellular deformations using the level set formalism.  BMC systems biology.  2(1).  68.
  • Arkowitz RA, Iglesias P (2008).  Basic principles of polarity establishment and maintenance.  EMBO reports.  9(9).  847-852.
  • Tang L, Franca-Koh J, Xiong Y, Chen M, Long Y, Bickford RM, Knecht DA, Iglesias P, Devreotes PN (2008).  tsunami, the Dictyostelium homolog of the Fused kinase, is required for polarization and chemotaxis.  Genes & development.  22(16).  2278-2290.
  • Iglesias P, Devreotes PN (2008).  Navigating through models of chemotaxis.  Current opinion in cell biology.  20(1).  35-40.
  • Iglesias PA, Khammash M, Munsky B, Sontag ED, Del Vecchio D (2007).  Systems biology and control - A tutorial.  Proceedings of the IEEE Conference on Decision and Control.
  • Andrews BW, Iglesias PA, Yi TM (2007).  Coping with noise in E. coli chemotaxis.  Forty-first Annual Conference on Information Sciences and Systems, CISS 2007 - Proceedings.
  • Andrews BW, Iglesias PA (2007).  Rate distortion theory in cellular signaling.  Forty-first Annual Conference on Information Sciences and Systems, CISS 2007 - Proceedings.
  • Kabacoff C, Xiong Y, Musib R, Reichl EM, Kim J, Iglesias PA, Robinson DN (2007).  Dynacortin facilitates polarization of chemotaxing cells.  BMC Biology.  5.
  • Andrews BW, Iglesias PA (2007).  Control engineering and systems biology.  Lecture Notes in Control and Information Sciences.  367.
  • Andrews BW, Iglesias PA (2007).  An information-theoretic characterization of the optimal gradient sensing response of cells.  PLoS Computational Biology.  3(8).
  • Li HY, Win PN, Wong CH, Iglesias PA, Zheng Y (2007).  Coordination of chromosome alignment and mitotic progression by the chromosome-based ran signal.  Cell Cycle.  6(15).
  • Yi TM, Andrews BW, Iglesias PA (2007).  Control Analysis of Bacterial Chemotaxis Signaling.  Methods in Enzymology.  422.
  • Poirier CC, Iglesias PA (2007).  An integrative approach to understanding mechanosensation.  Briefings in Bioinformatics.  8(4).
  • Chen L, Iijima M, Tang M, Landree MA, Huang YE, Xiong Y, Iglesias PA, Devreotes PN (2007).  PLA2 and PI3K/PTEN Pathways Act in Parallel to Mediate Chemotaxis.  Developmental Cell.  12(4).
  • Paliwal S, Iglesias PA, Campbell K, Hilioti Z, Groisman A, Levchenko A (2007).  MAPK-mediated bimodal gene expression and adaptive gradient sensing in yeast.  Nature.  446(7131).
  • Krishnan J, Iglesias PA (2007).  Receptor-mediated and intrinsic polarization and their interaction in chemotaxing cells.  Biophysical Journal.  92(3).
  • Andrews BW, Iglesias P (2007).  An information-theoretic characterization of the optimal gradient sensing response of cells.  PLoS computational biology.  3(8).  e153.
  • Li HY, Ng WP, Wong CH, Iglesias P, Zheng Y (2007).  Coordination of chromosome alignment and mitotic progression chromosome-based Ran signal.  CELL CYCLE-LANDES BIOSCIENCE-.  6(15).  1886.
  • Effler JC, Iglesias PA, Robinson DN (2007).  A Mechanosensory System Controls Cell Shape Changes during Mitosis.  Cell Cycle.  6(1).
  • Paliwal S, Iglesias P, Campbell K, Hilioti Z, Groisman A, Levchenko A (2007).  MAPK-mediated bimodal gene expression and adaptive gradient sensing in yeast.  Nature.  446(7131).  46-51.
  • Kabacoff C, Xiong Y, Musib R, Reichl EM, Kim J, Iglesias P, Robinson DN (2007).  Dynacortin facilitates polarization of chemotaxing cells.  BMC biology.  5(1).  53.
  • Poirier CC, Iglesias P (2007).  An integrative approach to understanding mechanosensation.  Briefings in bioinformatics.  8(4).  258-265.
  • Yi T, Andrews BW, Iglesias P (2007).  Control analysis of bacterial chemotaxis signaling.  Methods in enzymology.  422.  123-140.
  • Chen L, Iijima M, Tang M, Landree MA, Huang YE, Xiong Y, Iglesias P, Devreotes PN (2007).  PLA< sub> 2 and PI3K/PTEN Pathways Act in Parallel to Mediate Chemotaxis.  Developmental cell.  12(4).  603-614.
  • Effler JC, Iglesias P, Robinson DN (2007).  A mechanosensory system controls cell shape changes during mitosis.  CELL CYCLE-LANDES BIOSCIENCE-.  6(1).  30.
  • Andrews BW, Iglesias PA, Sontag ED (2006).  Signal detection and approximate adaptation implies an approximate internal model.  Proceedings of the IEEE Conference on Decision and Control.
  • Andrews BW, Yi TM, Iglesias PA (2006).  Optimal noise filtering in the chemotactic response of Escherichia coli.  PLoS Computational Biology.  2(11).
  • Effler JC, Kee YS, Berk JM, Tran MN, Iglesias PA, Robinson D (2006).  Mitosis-Specific Mechanosensing and Contractile-Protein Redistribution Control Cell Shape.  Current Biology.  16(19).
  • Kim J, Bates DG, Postlethwaite I, Ma L, Iglesias PA (2006).  Robustness analysis of biochemical network models.  IEE Proceedings: Systems Biology.  153(3).
  • Yang L, Iglesias PA (2006).  Positive feedback may cause the biphasic response observed in the chemoattractant-induced response of Dictyostelium cells.  Systems and Control Letters.  55(4).
  • Effler JC, Iglesias PA, Robinson DN (2006).  Regulating cell shape during cytokinesis.  Lecture Notes in Control and Information Sciences.  329.
  • Andrews BW, Yi T, Iglesias P (2006).  Optimal noise filtering in the chemotactic response of Escherichia coli.  PLoS computational biology.  2(11).  e154.
  • Kim J, Bates DG, Postlethwaite I, Ma L, Iglesias P (2006).  Robustness analysis of biochemical network models.  IEE Proceedings-Systems Biology.  153(3).  96-104.
  • Effler JC, Kee Y, Berk JM, Tran MN, Iglesias P, Robinson DN (2006).  Mitosis-specific mechanosensing and contractile-protein redistribution control cell shape.  Current biology.  16(19).  1962-1967.
  • Yang L, Iglesias P (2006).  Positive feedback may cause the biphasic response observed in the chemoattractant-induced response of< i> Dictyostelium cells.  Systems & control letters.  55(4).  329-337.
  • Vong QP, Cao K, Li HY, Iglesias PA, Zheng Y (2005).  Cell biology: Chromosome alignment and segregation regulated by ubiquitination of survivin.  Science.  310(5753).
  • Iglesias PA (2005).  Directional migration: A prototypical cellular control system.  Proceedings of the 44th IEEE Conference on Decision and Control, and the European Control Conference, CDC-ECC '05.  2005.
  • Kim J, Bates DG, Postlethwaite I, Ma L, Iglesias PA (2005).  Robustness analysis of biochemical networks using μ-analysis and hybrid optimisation.  Proceedings of the 44th IEEE Conference on Decision and Control, and the European Control Conference, CDC-ECC '05.  2005.
  • Prill RJ, Iglesias PA, Levchenko A (2005).  Dynamic properties of network motifs contribute to biological network organization..  PLoS biology.  3(11).
  • Prill RJ, Iglesias PA, Levchenko A (2005).  Dynamic properties of network motifs contribute to biological network organization.  PLoS Biology.  3(11).
  • Yang L, Iglesias PA (2005).  Feedback induced biphasic response in the chemotaxis pathway of Dictyostelium.  Proceedings of the American Control Conference.  6.
  • Krishnan J, Iglesias PA (2005).  A modelling framework describing the enzyme regulation of membrane lipids underlying gradient perception in Dictyostelium cells II: Input-output analysis.  Journal of Theoretical Biology.  235(4).
  • Prill RJ, Iglesias P, Levchenko A (2005).  Dynamic properties of network motifs contribute to biological network organization.  PLoS biology.  3(11).  e343.
  • Iglesias P (2005).  Directional migration: a prototypical cellular control system.  IEEE CONFERENCE ON DECISION AND CONTROL.  44(3).  2326.
  • Vong QP, Cao K, Li HY, Iglesias P, Zheng Y (2005).  Chromosome alignment and segregation regulated by ubiquitination of survivin.  Science.  310(5753).  1499-1504.
  • Ma L, Janetopoulos C, Yang L, Devreotes PN, Iglesias PA (2004).  Two complementary, local excitation, global inhibition mechanisms acting in parallel can explain the chemoattractant-induced regulation of PI(3,4,5)P 3 response in Dictyostelium cells.  Biophysical Journal.  87(6).
  • Manahan CL, Iglesias PA, Long Y, Devreotes PN (2004).  Chemoattractant signaling in Dictyostelium discoideum.  Annual Review of Cell and Developmental Biology.  20.
  • Zang G, Iglesias PA (2004).  Fading memory and stability.  Journal of the Franklin Institute.  340(6-7).
  • Paliwal S, Ma L, Krishnan J, Levchenko A, Iglesias PA (2004).  Responding to directional cues: A tale of two cells.  IEEE Control Systems Magazine.  24(4).
  • Krishnan J, Iglesias PA (2004).  A modeling framework describing the enzyme regulation of membrane lipids underlying gradient perception in Dictyostelium cells.  Journal of Theoretical Biology.  229(1).
  • Janetopoulos C, Ma L, Devreotes PN, Iglesias PA (2004).  Chemoattractant-induced phosphatidylinositol 3,4,5-trisphosphate accumulation is spatially amplified and adapts, independent of the actin cytoskeleton.  Proceedings of the National Academy of Sciences of the United States of America.  101(24).
  • Krishnan J, Iglesias PA (2004).  Uncovering directional sensing: where are we headed?.  Systems biology.  1(1).
  • Manahan CL, Iglesias P, Long Y, Devreotes PN (2004).  Chemoattractant signaling in Dictyostelium discoideum.  Annu. Rev. Cell Dev. Biol..  20.  223-253.
  • Janetopoulos C, Ma L, Devreotes PN, Iglesias P (2004).  Chemoattractant-induced phosphatidylinositol 3, 4, 5-trisphosphate accumulation is spatially amplified and adapts, independent of the actin cytoskeleton.  Proceedings of the National Academy of Sciences of the United States of America.  101(24).  8951-8956.
  • Kutscher B, Devreotes P, Iglesias PA (2004).  Local excitation, global inhibition mechanism for gradient sensing: an interactive applet..  Science's STKE : signal transduction knowledge environment.  2004(219).
  • Ma L, Janetopoulos C, Yang L, Devreotes PN, Iglesias P (2004).  Two Complementary, Local Excitation, Global Inhibition Mechanisms Acting in Parallel Can Explain the Chemoattractant-Induced Regulation of PI (3, 4, 5) P< sub> 3 Response in< i> Dictyostelium Cells.  Biophysical journal.  87(6).  3764-3774.
  • Kutscher B, Devreotes P, Iglesias P (2004).  Local excitation, global inhibition mechanism for gradient sensing: an interactive applet.  Science Signaling.  2004(219).  pl3.
  • Paliwal S, Ma L, Krishnan J, Levchenko A, Iglesias P (2004).  Responding to directional cues: a tale of two cells [biochemical signaling pathways].  Control Systems, IEEE.  24(4).  77-90.
  • Iglesias PA (2003).  Feedback control in intracellular signaling pathways: Regulating chemotaxis in dictyostelium discoideum.  European Journal of Control.  9(2-3).
  • Zang G, Iglesias PA (2003).  Nonlinear extension of Bode's integral based on an information-theoretic interpretation.  Systems and Control Letters.  50(1).
  • Zang G, Iglesias P (2003).  Fading memory and stability.  Journal of the Franklin Institute.  340(6).  489-502.
  • Krishnan J, Iglesias PA (2003).  Analysis of the signal transduction properties of a module of spatial sensing in eukaryotic chemotaxis.  Bulletin of Mathematical Biology.  65(1).
  • Iglesias P (2003).  Feedback Control in Intracellular Signaling Pathways: Regulating Chemotaxis in< i> Dictyostelium Discoideum.  European journal of control.  9(2).  227-236.
  • Zang G, Iglesias P (2003).  Nonlinear extension of Bode's integral based on an information-theoretic interpretation.  Systems & control letters.  50(1).  11-19.
  • Ma L, Iglesias PA (2002).  Quantifying robustness of biochemical network models.  BMC Bioinformatics.  3.
  • Ma L, Iglesias P (2002).  Robustness analysis of a self-oscillating molecular network in Dictyostelium Discoideum.  Proceedings of the IEEE Conference on Decision and Control.  3.
  • Levchenko A, Iglesias PA (2002).  Models of eukaryotic gradient sensing: Application to chemotaxis of amoebae and neutrophils.  Biophysical Journal.  82(1).
  • Iglesias PA (2002).  Logarithmic integrals and system dynamics: An analogue of Bode's sensitivity integral for continuous-time, time-varying systems.  Linear Algebra and Its Applications.  343.
  • Iglesias P (2002).  Logarithmic integrals and system dynamics: an analogue of Bode's sensitivity integral for continuous-time, time-varying systems.  Linear algebra and its applications.  343.  451-471.
  • Iglesias PA, Levchenko A (2002).  Modeling the cell's guidance system..  Science's STKE : signal transduction knowledge environment.  2002(148).
  • Levchenko A, Iglesias P (2002).  Models of eukaryotic gradient sensing: application to chemotaxis of amoebae and neutrophils.  Biophysical journal.  82(1).  50-63.
  • Ma L, Iglesias P (2002).  Robustness analysis of a self-oscillating molecular network in dictyostelium discoideum.  IEEE CONFERENCE ON DECISION AND CONTROL.  3.  2538-2543.
  • Iglesias P, Levchenko A (2002).  Modeling the cell's guidance system.  Science Signaling.  2002(148).  re12.
  • Ma L, Iglesias P (2002).  Quantifying robustness of biochemical network models.  BMC bioinformatics.  3(1).  38.
  • Iglesias PA (2001).  An analogue of Bode's integral for stable non linear systems: Relations to entropy.  Proceedings of the IEEE Conference on Decision and Control.  4.
  • Iglesias PA, Levchenko A (2001).  A general framework for achieving integral control in chemotactic biological signaling mechanisms.  Proceedings of the IEEE Conference on Decision and Control.  1.
  • Iglesias PA (2001).  Tradeoffs in linear time-varying systems: An analogue of Bode's sensitivity integral.  Automatica.  37(10).
  • Iglesias PA (2001).  A time-varying analogue of Jensen's formula.  Integral Equations and Operator Theory.  40(1).
  • O'Brien RT, Iglesias PA (2001).  On the poles and zeros of linear, time-varying systems.  IEEE Transactions on Circuits and Systems I: Fundamental Theory and Applications.  48(5).
  • Iglesias P (2001).  A time-varying analogue of Jensen's formula.  Integral Equations and Operator Theory.  40(1).  34-51.
  • Iglesias P, Zang G (2001).  Szego's First Limit Theorem in Terms of a Realization of a Continuous-Time Time-Varying System.  International Journal of Applied Mathematics and Computer Science.  11.  1261-1276.
  • Iglesias PA (2001).  An analogue of Bode's sensitivity integral for continuous-time, time-varying systems.  Proceedings of the American Control Conference.  1.
  • Iglesias P (2001).  Tradeoffs in linear time-varying systems: an analogue of Bode's sensitivity integral.  Automatica.  37(10).  1541-1550.
  • O’Brien R, Iglesias P (2001).  On the poles and zeros of linear, time-varying systems.  Circuits and Systems I: Fundamental Theory and Applications, IEEE Transactions on.  48(5).  565-577.
  • Iglesias PA (2000).  The strictly proper discrete-time controller for the normalized left-coprime factorization robust stabilization problem.  IEEE Transactions on Automatic Control.  45(3).
  • Iglesias PA, Peters MA (2000).  Entropy formula for nonlinear systems.  Journal of the Franklin Institute.  337(7).
  • Iglesias PA, Urban TJ (2000).  Loop Shaping Design for Missile Autopilots: Controller Configurations and Weighting Filter Selection.  Journal of Guidance, Control, and Dynamics.  23(3).
  • Iglesias P (2000).  The strictly proper discrete-time controller for the normalized left-coprime factorization robust stabilization problem.  Automatic Control, IEEE Transactions on.  45(3).  516-520.
  • Iglesias P, Urban TJ (2000).  Loop shaping design for missile autopilots: controller configurations and weighting filter selection.  Journal of Guidance, Control, and Dynamics.  23(3).  516-525.
  • Iglesias P, Peters MA (2000).  An entropy formula for nonlinear systems.  Journal of the Franklin Institute.  337(7).  859-874.
  • Peters MA, Iglesias PA (1999).  A spectral test for observability and reachability of time-varying systems.  SIAM Journal on Control and Optimization.  37(5).
  • O'Brien RT, Iglesias PA, Besançon-Voda A, Wang LY (1999).  Discussion on time-varying systems and adaptation: Some thoughts on and beyond 'robust controller design for linear, time-varying systems'.  European Journal of Control.  5(2-4).
  • Peters MA, Iglesias PA (1999).  The relationship between minimum entropy control and risk-sensitive control for time-varying systems.  IEEE Transactions on Automatic Control.  44(5).
  • Peters MA, Iglesias PA (1999).  Spectral test for observability and reachability of time-varying systems and the Riccati difference equation.  Proceedings of the IEEE Conference on Decision and Control.  3.
  • Iglesias PA (1999).  Use of frozen-time H∞ controllers in time-varying applications.  IEE Proceedings: Control Theory and Applications.  146(1).
  • Urban TJ, Iwaskiw P, Iglesias PA (1999).  Understanding missile autopilot design using the H∞ loop shaping design procedure.  IEEE Conference on Control Applications - Proceedings.  1.
  • Iglesias PA (1999).  Analytic constraints in feedback control of linear time-varying systems: Bode's sensitivity integral.  Proceedings of the American Control Conference.  6.
  • O'Brien RT, Iglesias PA (1999).  Robust controller design for linear, time-varying systems.  European Journal of Control.  5(2-4).
  • Iglesias PA (1999).  On the Riccati difference equation of optimal control.  Linear and Multilinear Algebra.  46(4).
  • Iglesias P (1999).  On the Riccati difference equation of optimal control.  Linear and Multilinear Algebra.  46(4).  313-326.
  • O'Brien RT, Iglesias PA (1998).  Pole/zero cancellations in time-varying systems.  International Journal of Control.  71(1).
  • O'Brien RT, Iglesias PA (1998).  Time-varying steering control for an autonomous highway vehicle.  Proceedings of the American Control Conference.  1.
  • Iglesias PA (1998).  Strictly proper discrete-time controller for the normalized left-coprime factorization robust stabilization problem.  Proceedings of the IEEE Conference on Decision and Control.  4.
  • O'Brien RT, Iglesias PA (1998).  Robust controller design for time-varying systems.  Proceedings of the IEEE Conference on Decision and Control.  4.
  • O'Brien RT, Iglesias PA (1998).  Closed loop cancellations in ℋ∞ control of time-varying systems.  International Journal of Control.  71(1).
  • Iglesias P, O’Brien, Jr RT (1998).  Pole/zero cancellations in time-varying systems.  International Journal of Control.  71(1).  103-130.
  • Iglesias P, O’Brien, Jr RT (1998).  Closed loop cancellations in H infinity control of time-varying systems.  International Journal of Control.  71(1).  163-189.
  • Peters MA, Iglesias PA (1997).  Spectral test for observability and detectability of discrete-time linear time-varying systems.  Proceedings of the IEEE Conference on Decision and Control.  4.
  • Peters MA, Iglesias PA (1997).  Continuous-time time-varying entropy.  Mathematics of Control, Signals, and Systems.  10(1).
  • Iglesias PA, Peters MA (1997).  On the induced norms of discrete-time and hybrid time-varying systems.  International Journal of Robust and Nonlinear Control.  7(9).
  • Peters MA, Iglesias PA (1997).  Minimum entropy control for discrete-time time-varying systems.  Automatica.  33(4).
  • Iglesias P, Peters MA (1997).  Continuous-time time-varying entropy.  Mathematics of Control, Signals and Systems.  10(1).  76-96.
  • O'Brien RT, Iglesias PA (1997).  Poles and zeros for time-varying systems.  Proceedings of the American Control Conference.  5.
  • Iglesias P, Peters MA (1997).  On the induced norms of discrete-time and hybrid time-varying systems.  International Journal of Robust and Nonlinear Control.  7(9).  811-833.
  • O'Brien RT, Iglesias PA, Urban TJ (1996).  Vehicle lateral control for automated highway systems.  IEEE Transactions on Control Systems Technology.  4(3).
  • Iglesias PA (1996).  An entropy formula for time-varying discrete-time control systems.  SIAM Journal on Control and Optimization.  34(5).
  • Iglesias P (1996).  An entropy formula for time-varying discrete-time control systems.  SIAM journal on control and optimization.  34(5).  1691-1706.
  • Iglesias P, Peters MA (1996).  Connections between minimum entropy control and linear exponential quadratic Gaussian control: The time-varying case.  Proceedings of the Conference on Information Sciences and Systems.  2.  674.
  • Peters MA, Iglesias PA (1995).  Connections between minimum entropy control and mixed H2/H∞ control for time-varying systems.  Systems and Control Letters.  26(5).
  • O'Brien RT, Iglesias PA, Urban TJ (1995).  Lane change maneuver via H∞ steering control methods.  IEEE Conference on Control Applications - Proceedings.
  • Peters MA, Iglesias PA (1995).  Minimum entropy controller as a mixed H2/H∞ controller: the time-varying case.  Proceedings of the IEEE Conference on Decision and Control.  2.
  • Iglesias PA (1995).  Input-output stability of sampled-data linear time-varying systems.  IEEE Transactions on Automatic Control.  40(9).
  • Iglesias P, Peters MA (1995).  Connections between minimum entropy control and mixed H2/H∞ control for time-varying systems.  Systems & control letters.  26(5).  341-347.
  • Iglesias P, Peters MA (1995).  Minimum entropy control for discrete-time time-varying systems: The disturbance feedforward problem.  Proc. 1995 Conf. Inf. Sci. Sys., Baltimore, MD.  130-135.
  • Iglesias P (1995).  Input-output stability of sampled-data linear time-varying systems.  IEEE transactions on automatic control.  40(9).  1646-1650.
  • Iglesias PA (1994).  On the stability of sampled-data linear time-varying feedback systems.  Proceedings of the IEEE Conference on Decision and Control.  1.
  • Iglesias PA (1993).  Input-output stability of sampled-data linear time-varying systems.  Proceedings of the IEEE Conference on Decision and Control.  1.
  • Iglesias PA, Mustafa D (1993).  State-Space Solution of the Discrete-Time Minimum Entropy Control Problem Via Separation.  IEEE Transactions on Automatic Control.  38(10).
  • Iglesias PA, Glover K (1991).  State-space approach to discrete-time H∞ control.  International Journal of Control.  54(5).
  • Popovic ZD, Iglesias P, Parco D, Robinette S (1991).  Characterization of microscopic electrical defects in xerographic photoreceptors.  Journal of imaging technology.  17(2).
  • Iglesias PA (1991).  On the use of robust regulators in adaptive control.  IFAC Symposia Series - Proceedings of a Triennial World Congress.  2.
  • Iglesias P, Parco D, Popovic Z, Robinette S (1991).  Characterization of microscopic electrical defects in xerographic photoreceptors.  Journal of imaging technology.  17(2).  71-75.
  • Glover K, Iglesias P (1991).  State-space approach to discrete-time H∞ control.  International Journal of Control.  54(5).  1031-1073.
  • Iglesias PA, Glover K (1990).  State space solutions to H∞ control problems at optimality: Full information problem.  Proceedings of the IEEE Conference on Decision and Control.  2.
  • Popovic ZD, Parco D, Iglesias P (1990).  Nature of microscopic electrical defects in organic photoreceptors.  Proceedings of SPIE - The International Society for Optical Engineering.  1253.
  • Iglesias PA, Mustafa D, Glover K (1990).  Discrete time H∞ controllers satisfying a minimum entropy criterion.  Systems and Control Letters.  14(4).
  • Glover K, Iglesias P (1990).  State space solutions to H-infinity control problems at optimality: full information problem.  Proceedings of the 29th IEEE Conference on Decision and Control.  2.  1032-1033.
  • Iglesias P, Popovic Z (1989).  Characterization of Microscopie Elelectrical Non-Uniformities in Xerographic Photoreceptors.  Fifth International Congress on Advances and Non-Impact printing Technologies.  11-14.
Books
  • Iglesias P, Ingalls BP (2010).  Control theory and systems biology.  MIT Press.
  • Iglesias P, Peters MA (1997).  Minimum entropy control for time-varying systems.  Springer.
Book Chapters
  • Bhattacharya S, Iglesias PA (2016).  Modeling excitable dynamics of chemotactic networks.  Methods in Molecular Biology.  1407.
  • Iglesias P (2016).  Dynamics of Gradient Sensing and Chemotaxis.  Encyclopedia of Cell Biology.  Academic Press.  4 - 9.
  • Iglesias P (2016).  A Modular View of the Signaling System Regulating Chemotaxis.  Physical Models of Cell Motility.  Springer International Publishing.  95-134.
  • Iglesias PA (2015).  Dynamics of Gradient Sensing and Chemotaxis.  Encyclopedia of Cell Biology.  4.
  • Iglesias P (2014).  Spatial Description of Biochemical Networks.  Encyclopedia of Systems and Control.  Springer London.  1-9.
  • Iglesias P (2012).  A systems biology view of adaptation in sensory mechanisms.  Advances in Systems Biology.  Springer New York.  499-516.
  • Channels WE, Iglesias PA (2010).  Simulating Filament Dynamics in Cellular Systems.  Elements of Computational Systems Biology.
  • Yang L, Iglesias P (2009).  Modeling spatial and temporal dynamics of chemotactic networks.  Chemotaxis.  Humana Press.  489-505.
  • Andrews BW, Iglesias P (2007).  Control engineering and systems biology.  Mathematical Methods for Robust and Nonlinear Control.  Springer London.  267-288.
  • Effler JC, Iglesias P, Robinson DN (2006).  Regulating cell shape during cytokinesis.  Control of Uncertain Systems: Modelling, Approximation, and Design.  Springer Berlin Heidelberg.  203-224.
  • Iglesias P, Peters MA (1997).  Induced Operator Norms.  Minimum Entropy Control for Time-Varying Systems.  Birkhäuser Boston.  26-45.
  • Iglesias P, Peters MA (1997).  Discrete-Time Entropy.  Minimum Entropy Control for Time-Varying Systems.  Birkhäuser Boston.  46-68.
  • Iglesias P, Peters MA (1997).  Connections With Related Optimal Control Problems.  Minimum Entropy Control for Time-Varying Systems.  Birkhäuser Boston.  69-93.
Other Publications
  • Iglesias P (1994).  On the stabilization of discrete-time linear time-varying systems.  Technical Report TR 94/08, Dept. Elec. & Comp. Eng., Johns Hopkins Univ., Baltimore, MD.
Conference Proceedings
  • Iglesias P (2013).  Excitable Systems in Cell Motility.  Proc. 52nd IEEE Conf. on Decision and Control.  52nd IEEE Conf. on Decision and Control.  757-762.
  • Shi C, Channels WE, Zheng Y, Iglesias P (2011).  A continuum computational model of mitotic matrix formation.  Information Sciences and Systems (CISS), 2011 45th Annual Conference on.  1-5.
  • Porter JR, Iglesias P, Burg JS, Espenshade PJ (2011).  Overcoming data limitations to identify a static nonlinearity in a biological signaling cascade.  Information Sciences and Systems (CISS), 2011 45th Annual Conference on.  1-6.
  • Xiong Y, Iglesias P (2009).  Automated characterization of amoeboid motility.  Information Sciences and Systems, 2009. CISS 2009. 43rd Annual Conference on.  369-370.
  • Andrews BW, Iglesias P, Yi T (2007).  Coping with Noise in E. coli Chemotaxis.  Information Sciences and Systems, 2007. CISS'07. 41st Annual Conference on.  442-443.
  • Iglesias P, Khammash M, Munsky B, Sontag ED, Del Vecchio D (2007).  Systems biology and control-A tutorial.  Decision and Control, 2007 46th IEEE Conference on.  1-12.
  • Andrews BW, Iglesias P (2007).  Rate distortion theory in cellular signaling.  Information Sciences and Systems, 2007. CISS'07. 41st Annual Conference on.  172-173.
  • Effler JC, Kee Y, Berk JM, Ren Y, Tran MN, Iglesias P, Robinson DN (2007).  Mechanosensing and contractile protein redistribution control cell shape during cytokinesis.  BIOPHYSICAL JOURNAL.  304A-304A.
  • Andrews BW, Iglesias P, Sontag ED (2006).  Signal detection and approximate adaptation implies an approximate internal model.  Decision and Control, 2006 45th IEEE Conference on.  2364-2369.
  • Yang L, Iglesias P (2005).  Feedback induced biphasic response in the chemotaxis pathway of Dictyostelium.  American Control Conference, 2005. Proceedings of the 2005.  4393-4398.
  • Kim J, Bates DG, Postlethwaite I, Ma L, Iglesias P (2005).  Robustness Analysis of Biochemical Networks Using $μ$-Analysis and Hybrid Optimisation.  Decision and Control, 2005 and 2005 European Control Conference. CDC-ECC'05. 44th IEEE Conference on.  6234-6239.
  • Yi T, Iglesias P, Ingalls B (2003).  Control theory in biology: From mca to chemotaxis.  In Tutorial at ICSB.
  • Iglesias P, Iwaskiw P, Urban TJ (1999).  Understanding missile autopilot design using the H∞ loop shaping design procedure.  Control Applications, 1999. Proceedings of the 1999 IEEE International Conference on.  1.  236-242.
  • Iglesias P (1999).  Analytic constraints in feedback control of linear time-varying systems: Bode's sensitivity integral.  American Control Conference, 1999. Proceedings of the 1999.  6.  3790-3794.
  • Iglesias P, O’Brien, Jr RT (1997).  Poles and zeros for time-varying systems.  American Control Conference, 1997. Proceedings of the 1997.  5.  2672-2676.
  • Iglesias P, Peters MA (1994).  Minimum entropy control for discrete-time time-varying systems: The full information problem.  Dept. Elec. & Comp. Eng., Johns Hopkins Univ.
  • Iglesias P (1994).  On the stability of sampled-data linear time-varying feedback systems.  Decision and Control, 1994., Proceedings of the 33rd IEEE Conference on.  1.  219-224.
  • Iglesias P, Parco D, Popovic ZD (1990).  Nature of microscopic electrical defects in organic photoreceptors.  SC-DL tentative.  175-182.
Back to top