Hristova, Kalina

Professor
Materials Science And Engineering

Shaffer Hall 204B
(410) 516-8939
kalina.hristova@jhu.edu

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About

Education
  • Ph.D. 1994, Duke University
  • Master of Science 1988, University of Sofia, Bulgaria
  • Bachelor of Science 1987, University of Sofia, Bulgaria
Experience
  • 2013 - 2016:  Chair, JHU Board of Review
  • 2013:  NIH Study Section, Molecular Structure and Function C, NIH
  • 2009:  NIH Study Section, ZRG1 BCMB-A 95 S, Chemistry and Biophysics Competetive Revisions, NIH
  • 2007 - 2011:  Associate Professor, Materials Science and Engineering, Johns Hopkins University, Baltimore, MD
  • 2002 - Present:  Joint, SOM Biomedical Engineering
  • 2001 - 2007:  Assistant Professor, Materials Science and Engineering, Johns Hopkins University, Baltimore, MD
  • 2001 - Present:  Faculty Mentor, Graduate Program in Molecular and Computational Biophysics
Research Areas
  • Antimicrobial peptides
  • Biomimetics
  • Biosurface interacitons
  • Cell Signaling
  • Interfacial films
  • Membrane cell biology
  • Membrane permeabilization
  • Peptide-bilayer interacitons
  • Structure, assembly, and function of biological membranes
  • Structure of membrane proteins
  • Structure of membranes and lipid bilayers
  • Surface engineering
Awards
  • 2018:  Elected Fellow, American Institute for Medical and Biological Engineering
  • 2017:  Wilsmore Fellow, University of Melbourne
  • 2016:  Elected Fellow, American Physical Society
  • 2016:  Elected Treasurer, The Biophysical Society
  • 2014:  Elected to Council, The Biophysical Society
  • 2011:  Chair, 2012 FASEB Research Conference (Molecular Biophysics of Cellular Membranes)
  • 2011:  Chair, 2012 Membrane Structure and Assembly
  • 2011:  Marlin U. Zimmerman Faculty Scholar, Whiting School of Engineering
  • 2007:  The Margaret Oakley Dayhoff Award, Biophysical Society
  • 2000:  Career Development Award, UC-Irvine
  • 1988:  Gold Badge of Scientific Merit, University of Sofia
Presentations
  • "Department of Molecular & Cellular Physiology seminar series".  November 1, 2019
  • "Biological Membranes and Membrane Proteins: Challenges for Theory and Experiment".  June 1, 2019
  • "Biophysical Society of Canada Annual Meeting: Chemistry, Biophysics, and Biodesign seminar series".  May 1, 2019
  • "Biochemistry, Biophysics, and Biodesign seminar series".  April 1, 2019
  • "Spring ACS National Meeting; Division of Computers in Chemistry".  April 1, 2019
  • "Department of Chemistry: University of Toronto, Canada".  March 1, 2019
  • "Applied Science and Biology seminar series".  November 1, 2018
  • "FASEB Science Research Conference “Molecular Biophysics of Membranes”".  June 1, 2018
  • "Fifth International Conference on Analytical and Nanoanalytical Methods for Biomedical and Environmental Sciences".  May 1, 2018
  • "Molecular Biophysics+Structural Biology Graduate Program Symposium University of Pittsburgh and Carnegie Mellon University".  May 1, 2018
  • "Workshop "Membrane models for Biophysics"".  March 1, 2018
  • "Workshop "Biomembrane models/tools"", Biophysical Society Annual Meeting.  February 1, 2018
  • "Melbourne University Chemical Society lecture".  October 1, 2017
  • "Queensland University of Technology Seminar".  October 1, 2017
  • "Walter and Eliza Hall Institute of Medical Research Seminar".  October 1, 2017
  • "Flinders Chemistry seminar series".  October 1, 2017
  • "Innovation in Two Photon Microspectroscopy", NSF-UWM Symposium.  August 1, 2017
  • "Membrane Proteins: Structure, Function, and Drug Development", 254 American Chemical Society National Meeting.  August 1, 2017
  • "Biological Membranes and Membrane Proteins: Challenges for Theory and Experiment".  June 1, 2017
  • "Symposium: New Insights into Signaling Networks", Endocrinology Society Annual Meeting.  April 1, 2017
  • Biophysics seminar series.  UT Southwestern Medical Center, Dallas, TX.  January 1, 2017
  • "Biophysics seminar series".  January 1, 2017
  • Chemistry seminar series.  Lehigh University, Bethlehem, PA.  October 1, 2016
  • Chemistry Seminar Series.  University of West Virginia, Morgantown, WV.  October 1, 2016
  • "Liposomes, Exosomes, and Virosomes: From Modeling Complex Membrane Processes to Medical Diagnostics and Drug Delivery", Biophysical Society Thematic Meeting.  Ascona, Switzerland.  September 1, 2016
  • Biomembrane Frontiers II Workshop: Emergent Design of Biomembranes.  UC Davis, CA.  September 1, 2016
  • Molecular Cell Biology seminar.  The Norwegian Radium Hospital, Oslo, Norway.  June 1, 2016
  • "The Fourth International Conference on Analytical and Nanoanalytical Methods for Biomedical and Environmental Sciences".  Brasov, Romania.  June 1, 2016
  • Chemistry seminar series.  University of Wisconsin, Madison, WI.  April 1, 2016
  • "Biophysics 101 Lecture", Biophysical Society Annual Meeting.  Los Angeles, CA.  February 1, 2016
  • "Receptor Tyrosine Kinases: Insight into dimerization, structure, and function", 2015 Workshop on Tethered Membranes.  Singapore.  November 1, 2015
  • Membrane Active Peptides and Proteins.  Shanghai, China.  November 1, 2015
  • Chemistry Seminar Series.  October 1, 2015
  • Optical Micro-spectroscopy & Molecular Imaging.  August 1, 2015
  • Biological Membranes and Membrane Proteins: Challenges for Theory and Experiments.  Telluride, CO.  July 1, 2015
  • Canadian Chemical Society Annual Meeting.  Ottawa, Canada.  June 1, 2015
  • Biochemistry and Molecular Biology seminar.  December 1, 2014
  • Chemistry/Biochemistry Seminar Series.  September 1, 2014
  • International Theoretical Course, ""Advances in Lipid-Protein Interactions: Understanding its Importance and Modulation in Cell Physiology".  Cuernavaca, Morelos, México.  August 1, 2014
  • FASEB Science Research Conference, "Molecular Biophysics of Membranes".  Big Sky, MO.  June 1, 2014
  • Third International Conference on Analytical and Nanoanalytical Methods for Biomedical and Environmental Sciences.  Brasov, Romania.  June 1, 2014
  • "Advanced Methods and Applications in Quantitative Fluorescence".  December 1, 2013
  • Physics/Biology seminar series.  Philadelphia, PA.  November 1, 2013
  • Chemistry/Biochemistry seminar series.  Wilmington, NC.  October 1, 2013
  • "Membrane Protein Folding and Functioning".  Telluride, CO.  August 1, 2013
  • "Biological Membranes and Membrane Proteins: Challenges for Theory and Experiment".  Snowmass Village, CO.  July 1, 2013
  • Theoretical Molecular Biophysics seminar series.  Berlin, Germany.  June 1, 2013
  • Institute for Bioscience and Biotechnology Research seminar series.  Rockville, MD.  May 1, 2013
  • Membrane Biochemistry and Biophysics and Molecular Signaling series.  Rockville, MD.  May 1, 2013
  • NSF-UWM Symposium: Open Forum for Innovation in Two-Photon Microspectroscopy.  Milwaukee, WI.  April 1, 2013
  • "Physics, Chemistry, and Biology of Membrane Proteins".  Tempe, AZ.  May 1, 2012
  • "Imaging the EGFR bio-system; from molecules to man” conference.  London, UK.  May 1, 2012
  • Biophysics and Biophysical Chemistry seminar series.  April 1, 2012
  • "Systems for Membrane Protein Reconstitution", Biophysical Society Annual Meeting.  San Diego, CA.  February 1, 2012
  • Australian Society of Biophysics Meeting.  Wollongong, Australia.  December 1, 2011
  • School of Pharmacy Seminar Series.  October 1, 2011
  • Biochemistry and Biophysics Seminar Series.  March 1, 2011
  • "Membrane Protein Structure and Function", ACS 241st National Meeting.  Anaheim, CA.  February 1, 2011
  • "Peptides in Biotechnology and Biomedicine", Joint 66th Southwest and 62nd Southeastern Regional Meeting of the ACS.  New Orleans, LA.  December 1, 2010
  • Materials Chemistry Seminar Series.  November 1, 2010
  • Physics Seminar Series.  November 1, 2010
  • Membrane Protein Interest Group seminar series.  Bethesda, MD.  October 1, 2010
  • Biochemistry Seminar Series.  October 1, 2010
  • Gordon Research Conference on Biointerface Science.  Les Diablerets, Switzerland.  September 1, 2010
  • BioNanoSciences Symposium.  September 1, 2010
  • Medicinal Physics and Biophysics Seminar Series.  September 1, 2010
  • "Frontiers in Membrane and Membrane Protein Biophysics: Experiments and Theory Experiments and Theory".  Irvine, CA.  August 1, 2010
  • "Receptor Tyrosine Kinases: Biology and Cancer", FASEB Research Conference.  Carefree, AZ.  July 1, 2010
  • Chemistry of Biopolymers seminar series.  April 1, 2010
  • "Biophysics of Membrane-Active Peptides".  Bad Honnef, Germany.  April 1, 2010

Publications

Journal Articles
  • Paul MD, Hristova K (2019).  The RTK Interactome: Overview and Perspective on RTK Heterointeractions.  Chemical Reviews.  119(9).  5881-5921.
  • Kim SY, Pittman AE, Zapata-Mercado E, King GM, Wimley WC, Hristova K (2019).  Mechanism of Action of Peptides That Cause the pH-Triggered Macromolecular Poration of Lipid Bilayers.  Journal of the American Chemical Society.  141(16).  6706-6718.
  • Gomez-Soler M, Gehring MP, Lechtenberg BC, Zapata-Mercado E, Hristova K, Pasquale EB (2019).  Engineering nanomolar peptide ligands that differentially modulate EphA2 receptor signaling.  Journal of Biological Chemistry.  294(22).  8791-8805.
  • King C, Hristova K (2019).  Direct measurements of VEGF–VEGFR2 binding affinities reveal the coupling between ligand binding and receptor dimerization.  Journal of Biological Chemistry.  294(23).  9064-9075.
  • Ahmed F, Hristova K (2018).  Dimerization of the Trk receptors in the plasma membrane: Effects of their cognate ligands.  Biochemical Journal.  475(22).  3669-3685.
  • King C, Wirth D, Workman S, Hristova K (2018).  Interactions between NRP1 and VEGFR2 molecules in the plasma membrane.  Biochimica et Biophysica Acta - Biomembranes.  1860(10).  2118-2125.
  • Walsh SM, Mathiasen S, Christensen SM, Fay JF, King C, Provasi D, Borrero E, Rasmussen SGF, Fung JJ, Filizola M, Hristova K, Kobilka B, Farrens DL, Stamou D (2018).  Single Proteoliposome High-Content Analysis Reveals Differences in the Homo-Oligomerization of GPCRs.  Biophysical Journal.  115(2).  300-312.
  • Li S, Kim SY, Pittman AE, King GM, Wimley WC, Hristova K (2018).  Potent Macromolecule-Sized Poration of Lipid Bilayers by the Macrolittins, A Synthetically Evolved Family of Pore-Forming Peptides.  Journal of the American Chemical Society.  140(20).  6441-6447.
  • Hristova KA, Paul M (2018).  The RTK Interactome: Overview and Perspective on RTK Hetero-Interactions.  Chemical Reviews.
  • Hristova KA, Sing D.R, Kanvinde P, King C, Pasquale E.B (2018).  The EphA2 receptor is activated through induction of distinct, ligand-dependent oligomeric structures.  Communications Biology.  1.  15.
  • King C, Wirth D, Workman S, Hristova K (2017).  Cooperative interactions between VEGFR2 extracellular Ig-like subdomains ensure VEGFR2 dimerization.  Biochimica et Biophysica Acta - General Subjects.  1861(11).  2559-2567.
  • Del Piccolo N, Hristova K (2017).  Quantifying the Interaction between EGFR Dimers and Grb2 in Live Cells.  Biophysical Journal.  113(6).  1353-1364.
  • Hristova K (2017).  Interactions between membrane receptors in cellular membranes.  Biochimica et Biophysica Acta - Biomembranes.  1859(9).  1397.
  • He J, Melnik LI, Komin A, Wiedman G, Fuselier T, Morris CF, Starr CG, Searson PC, Gallaher WR, Hristova K, Garry RF, Wimley WC (2017).  Ebola virus delta peptide is a viroporin.  Journal of Virology.  91(16).
  • Singh DR, Ahmed F, Sarabipour S, Hristova K (2017).  Intracellular Domain Contacts Contribute to Ecadherin Constitutive Dimerization in the Plasma Membrane.  Journal of Molecular Biology.  429(14).  2231-2245.
  • King C, Raicu V, Hristova K (2017).  Understanding the FRET signatures of interacting membrane proteins.  Journal of Biological Chemistry.  292(13).  5291-5310.
  • Komin A, Russell LM, Hristova KA, Searson PC (2017).  Peptide-based strategies for enhanced cell uptake, transcellular transport, and circulation: Mechanisms and challenges.  Advanced Drug Delivery Reviews.  110-111.  52-64.
  • Del Piccolo N, Sarabipour S, Hristova K (2017).  A new method to study heterodimerization of membrane proteins and its application to fibroblast growth factor receptors.  Journal of Biological Chemistry.  292(4).  1188-1301.
  • Wiedman G, Kim SY, Zapata-Mercado E, Wimley WC, Hristova K (2017).  pH-triggered, macromolecule-sized poration of lipid bilayers by synthetically evolved peptides.  Journal of the American Chemical Society.  139(2).  937-945.
  • Wiedman G, Kim SY, Zapata-Mercado E, Wimley WC, Hristova K (2017).  pH-Triggered, Macromolecule-Sized Poration of Lipid Bilayers by Synthetically Evolved Peptides.  Journal of the American Chemical Society.  139(2).  937-945.
  • Hristova K, Del Piccolo N, Sarabipour S (2017).  A New Method to Study Heterodimerization of Membrane Proteins and its Application to Fibroblast Growth Factor Receptors.  Journal of Biological Chemistry.
  • Singh DR, Ahmed F, Paul MD, Gedam M, Pasquale EB, Hristova K (2017).  The SAM domain inhibits EphA2 interactions in the plasma membrane.  Biochimica et Biophysica Acta - Molecular Cell Research.  1864(1).  31-38.
  • Singh DR, Ahmed F, Paul MD, Gedam M, Pasquale EB, Hristova K (2017).  The {SAM} domain inhibits EphA2 interactions in the plasma membrane.  Biochimica et Biophysica Acta (BBA) - Molecular Cell Research.  1864(1).  31 - 38.
  • Sarabipour S, Hristova K (2016).  Pathogenic Cysteine Removal Mutations in FGFR Extracellular Domains Stabilize Receptor Dimers and Perturb the TM Dimer Structure.  Journal of Molecular Biology.  428(20).  3903-3910.
  • Singh DR, Pasquale EB, Hristova K (2016).  A small peptide promotes EphA2 kinase-dependent signaling by stabilizing EphA2 dimers.  Biochimica et Biophysica Acta - General Subjects.  1860(9).  1922-1928.
  • Sarabipour S, Hristova K (2016).  Effect of the achondroplasia mutation on FGFR3 dimerization and FGFR3 structural response to fgf1 and fgf2: A quantitative FRET study in osmotically derived plasma membrane vesicles.  Biochimica et Biophysica Acta - Biomembranes.  1858(7).  1436-1442.
  • Sarabipour S, Ballmer-Hofer K, Hristova K (2016).  VEGFR-2 conformational switch in response to ligand binding.  eLife.  5(APRIL2016).
  • Sarabipour S, Ballmer-Hofer K, Hristova K (2016).  VEGFR-2 conformational switch in response to ligand binding.  eLife.  5.  e13876.
  • King C, Stoneman M, Raicu V, Hristova K (2016).  Fully quantified spectral imaging reveals in vivo membrane protein interactions.  Integrative Biology (United Kingdom).  8(2).  216-229.
  • Hristova K, Sarabipour S (2016).  Mechanism of FGF receptor dimerization and activation.  Nature Communications.  7.
  • Sarabipour S, Hristova K (2016).  Mechanism of FGF receptor dimerization and activation.  Nature Communications.  7.
  • Singh DR, Pasquale EB, Hristova K (2016).  A small peptide promotes EphA2 kinase-dependent signaling by stabilizing EphA2 dimers.  Biochimica et Biophysica Acta (BBA) - General Subjects.  1860(9).  1922 - 1928.
  • Sarabipour S, Hristova K (2016).  Pathogenic Cysteine Removal Mutations in {FGFR} Extracellular Domains Stabilize Receptor Dimers and Perturb the {TM} Dimer Structure.  Journal of Molecular Biology.  428(20).  3903 - 3910.
  • Sarabipour S, Hristova K (2016).  Effect of the achondroplasia mutation on {FGFR3} dimerization and {FGFR3} structural response to fgf1 and fgf2: A quantitative {FRET} study in osmotically derived plasma membrane vesicles.  Biochimica et Biophysica Acta (BBA) - Biomembranes.  1858(7, Part A).  1436 - 1442.
  • King C, Stoneman M, Raicu V, Hristova K (2016).  Fully quantified spectral imaging reveals in vivo membrane protein interactions.  Integr. Biol..  8(2).  216-229.
  • Singh DR, Ahmed F, King C, Gupta N, Salotto M, Pasquale EB, Hristova K (2015).  EphA2 receptor unliganded dimers suppress EphA2 pro-tumorigenic signaling.  Journal of Biological Chemistry.  290(45).  27271-27279.
  • Singh DR, Cao QQ, King C, Salotto M, Ahmed F, Zhou XY, Pasquale EB, Hristova K (2015).  Unliganded EphA3 dimerization promoted by the SAM domain.  Biochemical Journal.  471(1).  101-109.
  • Sarabipour S, Del Piccolo N, Hristova K (2015).  Characterization of Membrane Protein Interactions in Plasma Membrane Derived Vesicles with Quantitative Imaging Förster Resonance Energy Transfer.  Accounts of Chemical Research.  48(8).  2262-2269.
  • Sarabipour S, Chan RB, Zhou B, Di Paolo G, Hristova K (2015).  Analytical characterization of plasma membrane-derived vesicles produced via osmotic and chemical vesiculation.  Biochimica et Biophysica Acta - Biomembranes.  1848(7).  1591-1598.
  • Huang W, Besar K, Zhang Y, Yang S, Wiedman G, Liu Y, Guo W, Song J, Hemker K, Hristova K, Kymissis IJ, Katz HE (2015).  A high-capacitance salt-free dielectric for self-healable, printable, and flexible organic field effect transistors and chemical sensor.  Advanced Functional Materials.  25(24).  3745-3755.
  • Del Piccolo N, Placone J, Hristova K (2015).  Effect of thanatophoric dysplasia type i mutations on FGFR3 dimerization.  Biophysical Journal.  108(2).  272-278.
  • Del Piccolo N, Placone J, Hristova K (2015).  Effect of Thanatophoric Dysplasia Type I Mutations on FGFR3 Dimerization.  Biophysical Journal.  108(2).  272-278.
  • Sarabipour S, Chan RB, Zhou B, Di Paolo G, Hristova K (2015).  Analytical characterization of plasma membrane-derived vesicles produced via osmotic and chemical vesiculation.  Biochimica et Biophysica Acta (BBA) - Biomembranes.  1848(7).  1591 - 1598.
  • Sarabipour S, Hristova K (2015).  {FGFR3} Unliganded Dimer Stabilization by the Juxtamembrane Domain.  Journal of Molecular Biology.  427(8).  1705 - 1714.
  • Singh DR, Ahmed F, King C, Gupta N, Salotto M, Pasquale EB, Hristova K (2015).  EphA2 unliganded dimers suppress EphA2 pro-tumorigenic signaling.  Journal of Biological Chemistry.
  • Singh D, Cao Q, King C, Salotto M, Ahmed F, Zhou X, Pasquale E, Hristova K (2015).  Unliganded EphA3 dimerization promoted by the SAM domain.  Biochemical Journal.  471(1).  101-109.
  • Wiedman G, Wimley WC, Hristova K (2015).  Testing the limits of rational design by engineering pH sensitivity into membrane-active peptides.  Biochimica et Biophysica Acta (BBA) - Biomembranes.  1848(4).  951-957.
  • Sarabipour S, Del Piccolo N, Hristova K (2015).  Characterization of Membrane Protein Interactions in Plasma Membrane Derived Vesicles with Quantitative Imaging Forster Resonance Energy Transfer.  Accounts of Chemical Research.  48(8).  2262-2269.
  • He L, Hristova K (2015).  Quantification of the Effects of Mutations on Receptor Tyrosine Kinase (RTK) Activation in Mammalian Cells.  Receptor Tyrosine Kinases: Methods and Protocols.  1233.  81-87.
  • Wiedman G, Wimley WC, Hristova K (2015).  Testing the limits of rational design by engineering pH sensitivity into membrane-active peptides.  Biochimica et Biophysica Acta - Biomembranes.  1848(4).  951-957.
  • Hristova K, Hinderliter A (2015).  Of Rafts and Lipid Chain Lengths.  Biophysical Journal.  108(9).  2096 -.
  • Sarabipour S, Hristova K (2015).  FGFR3 unliganded dimer stabilization by the juxtamembrane domain.  Journal of Molecular Biology.  427(8).  1705-1714.
  • Kavran JM, McCabe JM, Byrne PO, Connacher MK, Wang Z, Ramek A, Sarabipour S, Shan Y, Shaw DE, Hristova K, Cole PA, Leahy DJ (2014).  How IGF-1 activates its receptor.  eLife.  3.
  • Wiedman G, Fuselier T, He J, Searson PC, Hristova K, Wimley WC (2014).  Highly efficient macromolecule-sized poration of lipid bilayers by a synthetically evolved peptide.  Journal of the American Chemical Society.  136(12).  4724-4731.
  • King C, Sarabipour S, Byrne P, Leahy DJ, Hristova K (2014).  The FRET signatures of noninteracting proteins in membranes: Simulations and experiments.  Biophysical Journal.  106(6).  1309-1317.
  • Sarabipour S, King C, Hristova K (2014).  Uninduced high-yield bacterial expression of fluorescent proteins.  Analytical Biochemistry.  449(1).  155-157.
  • Wimley WC, Hristova K (2014).  Interfacially active peptides and proteins Preface.  Biochimica Et Biophysica Acta-Biomembranes.  1838(9).  2139-2139.
  • Sarabipour S, King C, Hristova K (2014).  Uninduced high-yield bacterial expression of fluorescent proteins.  Analytical Biochemistry.  449.  155-157.
  • Placone J, He L, Del Piccolo N, Hristova K (2014).  Strong dimerization of wild-type ErbB2/Neu transmembrane domain and the oncogenic Val664Glu mutant in mammalian plasma membranes.  Biochimica Et Biophysica Acta-Biomembranes.  1838(9).  2326-2330.
  • Kavran JM, McCabe JM, Byrne PO, Connacher MK, Wang Z, Ramek A, Sarabipour S, Shan Y, Shaw DE, Hristova K, Cole PA, Leahy DJ (2014).  How IGF-1 Activates its Receptor.  Elife.  3.
  • Sarabipour S, Hristova K (2014).  FGF1 and FGF2 Induced FGFR3 Dimerization in Plasma Membrane Derived Vesicles.  Biophysical Journal.  106(2).  103A-103A.
  • Kavran JM, McCabe JM, Byrne PO, Connacher MK, Wang Z, Ramek A, Sarabipour S, Shan Y, Shaw DE, Hristova K, Cole PA, Leahy DJ (2014).  How IGF-1 activates its receptor.  eLife.  3.
  • King CR, Sarabipour S, Byrne P, Leahy D, Hristova K (2014).  The FRET Signatures of Non-Interacting Proteins in Cellular Membranes.  Biophysical Journal.  106(2).  719A-719A.
  • King C, Sarabipour S, Byrne P, Leahy DJ, Hristova K (2014).  The FRET Signatures of Noninteracting Proteins in Membranes: Simulations and Experiments.  Biophysical Journal.  106(6).  1309-1317.
  • Wiedman G, Fuselier T, He J, Searson P, Hristova K, Wimley WC (2014).  A Novel Functional Class of Pore-Forming Peptides.  Biophysical Journal.  106(2).  85A-86A.
  • Singh DR, King C, Placone J, Cao Q, Ghosh P, Hristova K (2014).  Dimerization of FGFR3 in Living Cells.  Biophysical Journal.  106(2).  480A-480A.
  • Placone J, He L, Del Piccolo N, Hristova K (2014).  Strong dimerization of wild-type ErbB2/Neu transmembrane domain and the oncogenic Val664Glu mutant in mammalian plasma membranes.  Biochimica et Biophysica Acta - Biomembranes.  1838(9).  2326-2330.
  • Wimley WC, Hristova K (2014).  Interfacially active peptides and proteins.  Biochimica et Biophysica Acta - Biomembranes.  1838(9).  2139.
  • Wiedman G, Fuselier T, He J, Searson P, Hristova K, Wimley WC (2014).  Highly Efficient Macromolecule-Sized Poration of Lipid Bilayers by a Synthetically Evolved Peptide.  Journal of the American Chemical Society.  136(12).  4724-4731.
  • Bocharov EV, Lesovoy DM, Goncharuk SA, Goncharuk MV, Hristova K, Arseniev AS (2013).  Structure of FGFR3 transmembrane domain dimer: Implications for signaling and human pathologies.  Structure.  21(11).  2087-2093.
  • He J, Kauffman WB, Fuselier T, Naveen SK, Voss TG, Hristova K, Wimley WC (2013).  Direct cytosolic delivery of polar cargo to cells by spontaneous membrane-translocating peptides.  Journal of Biological Chemistry.  288(41).  29974-29986.
  • Sarabipour S, Hristova K (2013).  FGFR3 transmembrane domain interactions persist in the presence of its extracellular domain.  Biophysical Journal.  105(1).  165-171.
  • Cruz J, Mihailescu M, Wiedman G, Herman K, Searson PC, Wimley WC, Hristova K (2013).  A membrane-translocating peptide penetrates into bilayers without significant bilayer perturbations.  Biophysical Journal.  104(11).  2419-2428.
  • Sarabipour S, Hristova K (2013).  Glycophorin A transmembrane domain dimerization in plasma membrane vesicles derived from CHO, HEK 293T, and A431 cells.  Biochimica et Biophysica Acta - Biomembranes.  1828(8).  1829-1833.
  • Wiedman G, Herman K, Searson P, Wimley WC, Hristova K (2013).  The electrical response of bilayers to the bee venom toxin melittin: Evidence for transient bilayer permeabilization.  Biochimica et Biophysica Acta - Biomembranes.  1828(5).  1357-1364.
  • Chen F, Sarabipour S, Hristova K (2013).  Multiple Consequences of a Single Amino Acid Pathogenic RTK Mutation: The A391E Mutation in FGFR3.  PLoS ONE.  8(2).
  • Cruz J, Mihailescu M, Wiedman G, Herman K, Searson P, Wimley WC, Hristova K (2013).  A Membrane-Translocating Peptide Penetrates into Bilayers without Significant Bilayer Perturbations.  Biophysical Journal.  104(11).  2419-2428.
  • Wiedman G, Herman K, Searson P, Wimley WC, Hristova K (2013).  Electrical Response of Bilayers to the Bee Venom Toxin Melittin.  Biophysical Journal.  104(2).  65A-65A.
  • Bocharov EV, Lesovoy DM, Goncharuk SA, Goncharuk MV, Hristova K, Arseniev AS (2013).  Structure of FGFR3 Transmembrane Domain Dimer: Implications for Signaling and Human Pathologies.  Structure.  21(11).  2087-2093.
  • He J, Kauffman WB, Fuselier T, Naveen SK, Voss TG, Hristova K, Wimley WC (2013).  Direct Cytosolic Delivery of Polar Cargo to Cells by Spontaneous Membrane-translocating Peptides.  Journal of Biological Chemistry.  288(41).  29974-29986.
  • Wiedman G, Herman K, Searson P, Wimley WC, Hristova K (2013).  The electrical response of bilayers to the bee venom toxin melittin: Evidence for transient bilayer permeabilization.  Biochimica Et Biophysica Acta-Biomembranes.  1828(5).  1357-1364.
  • Chen F, Sarabipour S, Hristova K (2013).  Multiple Consequences of a Single Amino Acid Pathogenic RTK Mutation: The A391E Mutation in FGFR3.  Plos One.  8(2).
  • Wiedman G, Herman K, Searson P, Wimley W, Hristova K (2013).  Electrical response of lipid bilayers to the bee venom toxin melittin using electrochemical impedance spectroscopy.  Abstracts of Papers of the American Chemical Society.  245.
  • He J, Fuselier T, Hristova K, Wimley WC (2013).  Exploring the Sequence Determinants of Spontaneous Membrane-Translocating Peptides.  Biophysical Journal.  104(2).  250A-250A.
  • Sarabipour S, Hristova K (2013).  GpA Dimerization in Plasma Membranes of CHO, HEK293T and A431 Cells.  Biophysical Journal.  104(2).  223A-223A.
  • Hristova K, Sarabipour S (2013).  GpA dimerization in plasma membrane vesicles derived from CHO, HEK 293T, and A431 cells.  Abstracts of Papers of the American Chemical Society.  245.
  • Hristova K (2013).  Production of plasma membrane vesicles with chloride salts and their utility as a cell membrane mimetic for biophysical characterization of membrane protein interactions.  Abstracts of Papers of the American Chemical Society.  245.
  • Sarabipour S, Hristova K (2013).  Glycophorin A transmembrane domain dimerization in plasma membrane vesicles derived from CHO, HEK 293T, and A431 cells.  Biochimica Et Biophysica Acta-Biomembranes.  1828(8).  1829-1833.
  • He J, Fuselier T, Hristova K, Wimley WC (2013).  Sequence determinants of spontaneous membrane-translocating peptides.  Abstracts of Papers of the American Chemical Society.  245.
  • Sarabipour S, Hristova K (2013).  FGFR3 Transmembrane Domain Interactions Persist in the Presence of Its Extracellular Domain.  Biophysical Journal.  105(1).  165-171.
  • He L, Hristova K (2012).  Consequences of replacing EGFR juxtamembrane domain with an unstructured sequence.  Scientific Reports.  2.
  • Del Piccolo N, Placone J, He L, Agudelo SC, Hristova K (2012).  Production of plasma membrane vesicles with chloride salts and their utility as a cell membrane mimetic for biophysical characterization of membrane protein interactions.  Analytical Chemistry.  84(20).  8650-8655.
  • Placone J, Hristova K (2012).  Direct Assessment of the Effect of the Gly380Arg Achondroplasia Mutation on FGFR3 Dimerization Using Quantitative Imaging FRET.  PLoS ONE.  7(10).
  • He J, Hristova K, Wimley WC (2012).  A highly charged voltage-sensor helix spontaneously translocates across membranes.  Angewandte Chemie - International Edition.  51(29).  7150-7153.
  • Stahl PJ, Cruz JC, Li Y, Michael Yu S, Hristova K (2012).  On-the-resin N-terminal modification of long synthetic peptides.  Analytical Biochemistry.  424(2).  137-139.
  • Ohsfeldt E, Huang SH, Baycin-Hizal D, Kristoffersen L, Le TMT, Li E, Hristova K, Betenbaugh MJ (2012).  Increased expression of the integral membrane proteins EGFR and FGFR3 in anti-apoptotic Chinese hamster ovary cell lines.  Biotechnology and Applied Biochemistry.  59(3).  155-162.
  • He L, Serrano C, Niphadkar N, Shobnam N, Hristova K (2012).  Effect of the G375C and G346E achondroplasia mutations on FGFR3 activation.  PLoS ONE.  7(4).
  • Lin J, Motylinski J, Krauson AJ, Wimley WC, Searson PC, Hristova K (2012).  Interactions of membrane active peptides with planar supported bilayers: An impedance spectroscopy study.  Langmuir.  28(14).  6088-6096.
  • He L, Hristova K (2012).  Physical-chemical principles underlying RTK activation, and their implications for human disease.  Biochimica et Biophysica Acta - Biomembranes.  1818(4).  995-1005.
  • Li E, Wimley WC, Hristova K (2012).  Transmembrane helix dimerization: Beyond the search for sequence motifs.  Biochimica et Biophysica Acta - Biomembranes.  1818(2).  183-193.
  • Li E, Wimley WC, Hristova K (2012).  Transmembrane helix dimerization: Beyond the search for sequence motifs.  Biochimica Et Biophysica Acta-Biomembranes.  1818(2).  183-193.
  • Stahl PJ, Cruz JC, Li Y, Yu SM, Hristova K (2012).  On-the-resin N-terminal modification of long synthetic peptides.  Analytical Biochemistry.  424(2).  137-139.
  • Ohsfeldt E, Huang S, Baycin-Hizal D, Kristoffersen L, Le TT, Li E, Hristova K, Betenbaugh M (2012).  Increased expression of the integral membrane proteins EGFR and FGFR3 in anti-apoptotic Chinese hamster ovary cell lines.  Biotechnology and Applied Biochemistry.  59(3).  155-162.
  • Del Piccolo N, Placone J, He L, Agudelo SC, Hristova K (2012).  Production of Plasma Membrane Vesicles with Chloride Salts and Their Utility as a Cell Membrane Mimetic for Biophysical Characterization of Membrane Protein Interactions.  Analytical Chemistry.  84(20).  8650-8655.
  • Placone J, Hristova K (2012).  Direct Assessment of the Effect of the Gly380Arg Achondroplasia Mutation on FGFR3 Dimerization Using Quantitative Imaging FRET.  Plos One.  7(10).
  • Lin J, Motylinski J, Krauson AJ, Wimley WC, Searson P, Hristova K (2012).  Interactions of Membrane Active Peptides with Planar Supported Bilayers: An Impedance Spectroscopy Study.  Langmuir.  28(14).  6088-6096.
  • He L, Hristova K (2012).  Physical-chemical principles underlying RTK activation, and their implications for human disease.  Biochimica Et Biophysica Acta-Biomembranes.  1818(4).  995-1005.
  • He L, Serrano C, Niphadkar N, Shobnam N, Hristova K (2012).  Effect of the G375C and G346E Achondroplasia Mutations on FGFR3 Activation.  Plos One.  7(4).
  • Hristova K (2012).  Platforms for Characterization of Membrane Protein Interactions.  Biophysical Journal.  102(3).  439A-439A.
  • He J, Hristova K, Wimley WC (2012).  A Highly Charged Voltage-Sensor Helix Spontaneously Translocates across Membranes.  Angewandte Chemie-International Edition.  51(29).  7150-7153.
  • Wimley WC, Hristova K (2012).  The Isolated S4 Voltage Sensor Helix Translocates Spontaneously Across Membranes.  Biophysical Journal.  102(3).  615A-615A.
  • Wiedman G, Wimley W, Searson P, Hristova K (2012).  Effect of Melittin and Gain-of-Function Melittin Analogs, Discovered by High-Throughput Screening, on Bilayer Properties: An Electrical Impedance Spectroscopy Study.  Biophysical Journal.  102(3).  91A-91A.
  • He L, Hristova K (2012).  Consequences of replacing EGFR juxtamembrane domain with an unstructured sequence.  Scientific Reports.  2.
  • Chen F, Hristova K (2011).  The physical basis of FGFR3 response to fgf1 and fgf2.  Biochemistry.  50(40).  8576-8582.
  • He L, Hoffmann AR, Serrano C, Hristova K, Wimley WC (2011).  High-throughput selection of transmembrane sequences that enhance receptor tyrosine kinase activation.  Journal of Molecular Biology.  412(1).  43-54.
  • Chen F, Degnin C, Laederich M, Horton WA, Hristova K (2011).  The A391E mutation enhances FGFR3 activation in the absence of ligand.  Biochimica et Biophysica Acta - Biomembranes.  1808(8).  2045-2050.
  • Sánchez-Martín MJ, Hristova K, Pujol M, Gómara MJ, Haro I, Asunción Alsina M, Antònia Busquets M (2011).  Analysis of HIV-1 fusion peptide inhibition by synthetic peptides from E1 protein of GB virus C.  Journal of Colloid and Interface Science.  360(1).  124-131.
  • Marks JR, Placone J, Hristova K, Wimley WC (2011).  Spontaneous membrane-translocating peptides by orthogonal high-throughput screening.  Journal of the American Chemical Society.  133(23).  8995-9004.
  • He L, Shobnam N, Wimley WC, Hristova K (2011).  FGFR3 heterodimerization in achondroplasia, the most common form of human dwarfism.  Journal of Biological Chemistry.  286(15).  13272-13281.
  • Chen F, Degin C, Laederich M, Horton W, Hristova K (2011).  The A391E Mutation Enhances FGFR3 Activation in the Absence of Ligand.  Biophysical Journal.  100(3).  419-419.
  • Lin J, Krauson AJ, Wimley WC, Searson P, Hristova K (2011).  Interactions of Membrane Active Peptides with Planar Supported Bilayers: an Impedance Spectroscopy Study.  Biophysical Journal.  100(3).  351-351.
  • Sarabipour S, Li E, Hristova K (2011).  Effect of FGFR3 Juxtamembrane Domain on FGFR3 Dimerization.  Biophysical Journal.  100(3).  546-546.
  • Placone J, Hristova K (2011).  Probing Skeletal Dysplasias Caused by Mutations of FGFR3 Using Qi-FRET.  Biophysical Journal.  100(3).  547-547.
  • Serrano CM, He L, Hoffman A, Wimley WC, Hristova K (2011).  The Homodimerization Propensities of Transmembrane Helices Selected from a Combinatorial Library Characterized using In Vivo Phosphorylation and Dimerization Assays.  Biophysical Journal.  100(3).  419-419.
  • Wimley WC, Hristova K (2011).  Antimicrobial Peptides: Successes, Challenges and Unanswered Questions.  Journal of Membrane Biology.  239(1-2).  27-34.
  • Marks JR, Placone J, Hristova K, Wimley WC (2011).  Spontaneous Membrane-Translocating Peptides by Orthogonal High-Throughput Screening.  Journal of the American Chemical Society.  133(23).  8995-9004.
  • He L, Shobnam N, Hristova K (2011).  Specific inhibition of a pathogenic receptor tyrosine kinase by its transmembrane domain.  Biochimica Et Biophysica Acta-Biomembranes.  1808(1).  253-259.
  • Jesus Sanchez-Martin M, Hristova K, Pujol M, Gomara MJ, Haro I, Asuncion Alsina M, Antonia Busquets M (2011).  Analysis of HIV-1 fusion peptide inhibition by synthetic peptides from E1 protein of GB virus C.  Journal of Colloid and Interface Science.  360(1).  124-131.
  • He L, Shobnam N, Hristova K (2011).  Specific inhibition of a pathogenic receptor tyrosine kinase by its transmembrane domain.  Biochimica et Biophysica Acta - Biomembranes.  1808(1).  253-259.
  • Wimley WC, Hristova K (2011).  Antimicrobial peptides: Successes, challenges and unanswered questions.  Journal of Membrane Biology.  239(1-2).  27-34.
  • Hristova K, Wimley WC (2011).  A look at arginine in membranes.  Journal of Membrane Biology.  239(1-2).  49-56.
  • Chen L, Hristova K (2011).  Characterization of Lipid Asymmetry in Plasma Membrane-Derived Vesicles.  Biophysical Journal.  100(3).  338-338.
  • Chen F, Degnin C, Laederich M, Horton WA, Hristova K (2011).  The A391E mutation enhances FGFR3 activation in the absence of ligand.  Biochimica Et Biophysica Acta-Biomembranes.  1808(8).  2045-2050.
  • Cruz JC, Mihailescu M, Wimley W, Hristova K (2011).  Studies of Membrane-Active Peptides Using Neutron Diffraction.  Biophysical Journal.  100(3).  334-334.
  • Schick S, Hristova K (2011).  Assembly of the M2 tetramer is strongly modulated by lipid chain length.  Abstracts of Papers of the American Chemical Society.  241.
  • Chen F, Hristova K (2011).  The Physical Basis of FGFR3 Response to fgf1 and fgf2.  Biochemistry.  50(40).  8576-8582.
  • Hristova K, Wimley WC (2011).  A Look at Arginine in Membranes.  Journal of Membrane Biology.  239(1-2).  49-56.
  • Marks JR, Placone J, Hristova K, Wimley WC (2011).  Peptides with multiple arginine residues can spontaneously translocate across lipid bilayer membranes.  Abstracts of Papers of the American Chemical Society.  241.
  • He L, Shobnam N, Wimley WC, Hristova K (2011).  FGFR3 Heterodimerization in Achondroplasia, the Most Common Form of Human Dwarfism.  Journal of Biological Chemistry.  286(15).  13272-13281.
  • He L, Agudelo SC, Hristova K (2011).  Role of EGFR Juxtamembrane Domain in EGFR Activation.  Biophysical Journal.  100(3).  418-418.
  • He L, Hoffmann AR, Serrano C, Hristova K, Wimley WC (2011).  High-Throughput Selection of Transmembrane Sequences That Enhance Receptor Tyrosine Kinase Activation.  Journal of Molecular Biology.  412(1).  43-54.
  • Marks JR, Hristova K, Wimley WC (2011).  Peptides with Multiple Arginines can Spontaneously Translocate across Lipid Vesicle Membranes and across Living Cell Membranes.  Biophysical Journal.  100(3).  494-494.
  • Chen L, Placone J, Novicky L, Hristova K (2010).  The extracellular domain of fibroblast growth factor receptor 3 inhibits ligand-independent dimerization.  Science Signaling.  3(150).
  • He L, Horton W, Hristova K (2010).  Physical basis behind achondroplasia, the most common form of human dwarfism.  Journal of Biological Chemistry.  285(39).  30103-30114.
  • Lin J, Szymanski J, Searson PC, Hristova K (2010).  Electrically addressable, biologically relevant surface-supported bilayers.  Langmuir.  26(14).  12054-12059.
  • Chen L, Novicky L, Merzlyakov M, Hristov T, Hristova K (2010).  Measuring the energetics of membrane protein dimerization in mammalian membranes.  Journal of the American Chemical Society.  132(10).  3628-3635.
  • Lin J, Szymanski J, Chsearson P, Hristova K (2010).  Effect of a polymer cushion on the electrical properties and stability of surface-supported lipid bilayers.  Langmuir.  26(5).  3544-3548.
  • Chen L, Novicky LJ, Merzlyakov M, Hristova K (2010).  Energetics of Glycophorin A Dimerization in Mammalian Plasma Membranes.  Biophysical Journal.  98(3).  224A-224A.
  • Sarabipour S, Hristova K (2010).  Quantitative Measurements of Receptor Interactions in Mammalian Cells: Implications for Human Pathologies.  Biophysical Journal.  98(3).  245A-246A.
  • Schick S, Chen L, Li E, Lin J, Koeper I, Hristova K (2010).  Assembly of the M2 Tetramer Is Strongly Modulated by Lipid Chain Length.  Biophysical Journal.  99(6).  1810-1817.
  • Marks JR, Krauson AJ, Hristova K, Wimley WC (2010).  Membrane-Active Peptides: Stable Pore-Forming or Cell-Penetrating Peptides Selected With Orthogonal High-Throughput Screening.  Biophysical Journal.  98(3).  85A-85A.
  • Chen L, Novicky L, Merzlyakov M, Hristov T, Hristova K (2010).  Measuring the Energetics of Membrane Protein Dimerization in Mammalian Membranes.  Journal of the American Chemical Society.  132(10).  3628-3635.
  • Lin J, Szymanski J, Searson P, Hristova K (2010).  Effect of a Polymer Cushion on the Electrical Properties and Stability of Surface-Supported Lipid Bilayers.  Langmuir.  26(5).  3544-3548.
  • Chen L, Placone J, Novicky L, Hristova K (2010).  The Extracellular Domain of Fibroblast Growth Factor Receptor 3 Inhibits Ligand-Independent Dimerization.  Science Signaling.  3(150).
  • Lin J, Szymanski J, Searson P, Hristova K (2010).  Design of a Biologically Relevant Supported Bilayer Platform for the Study of Membrane Active Peptides.  Biophysical Journal.  98(3).  285A-285A.
  • He L, Horton W, Hristova K (2010).  Physical Basis behind Achondroplasia, the Most Common Form of Human Dwarfism.  Journal of Biological Chemistry.  285(39).  30103-30114.
  • Lin J, Szymanski J, Searson P, Hristova K (2010).  Electrically Addressable, Biologically Relevant Surface-Supported Bilayers.  Langmuir.  26(14).  12054-12059.
  • He L, Hristova K (2010).  The Physical Basis Behind Achondroplasia, the Most Common Form of Human Dwarfism.  Biophysical Journal.  98(3).  246A-246A.
  • Li E, Hristova K (2010).  Receptor tyrosine kinase transmembrane domains Function, dimer structure and dimerization energetics.  Cell Adhesion & Migration.  4(2).  249-254.
  • Lin J, Szymanski J, Searson P, Hristova K (2010).  Electrically addressable, biologically relevant surface supported bilayers.  Abstracts of Papers of the American Chemical Society.  240.
  • Li E, Hristova K (2010).  Receptor tyrosine kinase transmembrane domains: Function, dimer structure and dimerization energetics.  Cell Adhesion and Migration.  4(2).  249-254.
  • Schick S, Chen L, Li E, Lin J, Köper I, Hristova K (2010).  Assembly of the M2 Tetramer Is Strongly Modulated by Lipid Chain Length.  Biophysical Journal.  99(6).  1810-1817.
  • Snider C, Jayasinghe S, Hristova K, White SH (2009).  MPEx: A tool for exploring membrane proteins.  Protein Science.  18(12).  2624-2628.
  • Li E, Merzlyakov M, Lin J, Searson P, Hristova K (2009).  Utility of surface-supported bilayers in studies of transmembrane helix dimerization.  Journal of Structural Biology.  168(1).  53-60.
  • O'Connor S, Li E, Majors BS, He L, Placone J, Baycin D, Betenbaugh MJ, Hristova K (2009).  Increased expression of the integral membrane protein ErbB2 in Chinese hamster ovary cells expressing the anti-apoptotic gene Bcl-x L.  Protein Expression and Purification.  67(1).  41-47.
  • Soong R, Merzlyakov M, Hristova K (2009).  Hill coefficient analysis of transmembrane helix dimerization.  Journal of Membrane Biology.  230(1).  49-55.
  • Walkenhorst WF, Merzlyakov M, Hristova K, Wimley WC (2009).  Polar residues in transmembrane helices can decrease electrophoretic mobility in polyacrylamide gels without causing helix dimerization.  Biochimica et Biophysica Acta - Biomembranes.  1788(6).  1321-1331.
  • Han X, Hristova K (2009).  Viewing the bilayer hydrocarbon core using neutron diffraction.  Journal of Membrane Biology.  227(3).  123-131.
  • Li E, Merzlyakov M, Lin J, Searson P, Hristova K (2009).  Utility of surface-supported bilayers in studies of transmembrane helix dimerization.  Journal of Structural Biology.  168(1).  53-60.
  • Chen L, Merzlyakov M, Cohen T, Shai Y, Hristova K (2009).  Energetics of ErbB1 transmembrane domain dimerization in lipid bilayers.  Biophysical Journal.  96(11).  4622-4630.
  • Snider C, Jayasinghe S, Hristova K, White SH (2009).  MPEx: A tool for exploring membrane proteins.  Protein Science.  18(12).  2624-2628.
  • Hristova K (2009).  New tools for studies of membrane protein dimerization in mammalian membranes.  Abstracts of Papers of the American Chemical Society.  237.
  • Han X, Hristova K (2009).  Viewing the Bilayer Hydrocarbon Core Using Neutron Diffraction.  Journal of Membrane Biology.  227(3).  123-131.
  • Soong R, Merzlyakov M, Hristova K (2009).  Hill Coefficient Analysis of Transmembrane Helix Dimerization.  Journal of Membrane Biology.  230(1).  49-55.
  • Chen L, Merzlyakov M, Cohen T, Shai Y, Hristova K (2009).  Energetics of ErbB1 Transmembrane Domain Dimerization in Lipid Bilayers.  Biophysical Journal.  96(11).  4622-4630.
  • Li E, Placone J, Hristova K (2009).  EGFR ligand-mediated activation: insights from a quantitative study in mammalian membranes.  Faseb Journal.  23.
  • Walkenhorst WF, Merzlyakov M, Hristova K, Wimley WC (2009).  Polar residues in transmembrane helices can decrease electrophoretic mobility in polyacrylamide gels without causing helix dimerization.  Biochimica Et Biophysica Acta-Biomembranes.  1788(6).  1321-1331.
  • O’Connor S, Li E, Majors BS, He L, Placone J, Baycin D, Betenbaugh M, Hristova K (2009).  Increased expression of the integral membrane protein ErbB2 in Chinese hamster ovary cells expressing the anti-apoptotic gene Bcl-x(L).  Protein Expression and Purification.  67(1).  41-47.
  • He L, Hristova K (2008).  Pathogenic Activation of Receptor Tyrosine Kinases in Mammalian Membranes.  Journal of Molecular Biology.  384(5).  1130-1142.
  • Mikhail M, Kalina H (2008).  Chapter 6 Forster Resonance Energy Transfer Measurements of Transmembrane Helix Dimerization Energetics.  Methods in Enzymology.  450.  107-127.
  • Chang WK, Wimley WC, Searson PC, Hristova K, Merzlyakov M (2008).  Characterization of antimicrobial peptide activity by electrochemical impedance spectroscopy.  Biochimica et Biophysica Acta - Biomembranes.  1778(10).  2430-2436.
  • Posokhov YO, Merzlyakov M, Hristova K, Ladokhin AS (2008).  A simple "proximity" correction for Förster resonance energy transfer efficiency determination in membranes using lifetime measurements.  Analytical Biochemistry.  380(1).  134-136.
  • Li E, Placone J, Merzlyakov M, Hristova K (2008).  Quantitative measurements of protein interactions in a crowded cellular environment.  Analytical Chemistry.  80(15).  5976-5985.
  • Han X, Hristova K, Wimley WC (2008).  Protein folding in membranes: Insights from neutron diffraction studies of a membrane β-sheet oligomer.  Biophysical Journal.  94(2).  492-505.
  • Lin J, Merzlyakov M, Hristova K, Searson P (2008).  Impedance spectroscopy of bilayer membranes on single crystal silicon.  Biointerphases.  3(2).  FA33-FA40.
  • He L, Hristova K (2008).  Pathogenic Activation of Receptor Tyrosine Kinases in Mammalian Membranes.  Journal of Molecular Biology.  384(5).  1130-1142.
  • Hristova K (2008).  COLL 52-Structural characterization of proteins in multilayers.  Abstracts of Papers of the American Chemical Society.  236.
  • Merzlyakov M, Li E, Hristova K (2008).  Surface supported bilayer platform for studies of lateral association of proteins in membranes.  Biointerphases.  3(2).
  • Lin J, Merzlyakov M, Hristova K, Searsona PC (2008).  Impedance spectroscopy of bilayer membranes on single crystal silicon.  Biointerphases.  3(2).
  • Posokhov YO, Merzlyakov M, Hristova K, Ladokhin AS (2008).  A simple "proximity" correction for Forster resonance energy transfer efficiency determination in membranes using lifetime measurements.  Analytical Biochemistry.  380(1).  134-136.
  • Merzlyakov M, Li E, Hristova K (2008).  Surface supported bilayer platform for studies of lateral association of proteins in membranes (Mini Review).  Biointerphases.  3(2).  FA80-FA84.
  • Li E, Placone J, Merzlyakov M, Hristova K (2008).  Quantitative measurements of protein interactions in a crowded cellular environment.  Analytical Chemistry.  80(15).  5976-5985.
  • Chang WK, Wimley WC, Searson P, Hristova K, Merzlyakov M (2008).  Characterization of antimicrobial peptide activity by electrochemical impedance spectroscopy.  Biochimica Et Biophysica Acta-Biomembranes.  1778(10).  2430-2436.
  • Han X, Hristova K, Wimley WC (2008).  Protein folding in membranes: Insights from neutron diffraction studies of a membrane beta-sheet oligomer.  Biophysical Journal.  94(2).  492-505.
  • Nikolov V, Lin J, Merzlyakov M, Hristova K, Searson PC (2007).  Electrical measurements of bilayer membranes formed by Langmuir-Blodgett deposition on single-crystal silicon.  Langmuir.  23(26).  13040-13045.
  • You M, Spangler J, Li E, Han X, Ghosh P, Hristova K (2007).  Effect of pathogenic cysteine mutations on FGFR3 transmembrane domain dimerization in detergents and lipid bilayers.  Biochemistry.  46(39).  11039-11046.
  • Sahalov H, O'Brien B, Stebe KJ, Hristova K, Searson PC (2007).  Influence of applied potential on the impedance of alkanethiol SAMs.  Langmuir.  23(19).  9681-9685.
  • Merzlyakov M, Chen L, Hristova K (2007).  Studies of receptor tyrosine kinase transmembrane domain interactions: The EmEx-FRET method.  Journal of Membrane Biology.  215(2-3).  93-103.
  • Merzlyakov M, Chen L, Hristova K (2007).  Studies of receptor tyrosine kinase transmembrane domain interactions: The EmEx-FRET method.  Journal of Membrane Biology.  215(2-3).  93-103.
  • Nikolov V, Lin J, Merzlyakov M, Hristova K, Searson P (2007).  Electrical measurements of bilayer membranes formed by Langmuir-Blodgett deposition on single-crystal silicon.  Langmuir.  23(26).  13040-13045.
  • Li E, Chen F, Merzlyakov M, Placone J, Hristova K (2007).  Measurements of FGFR3 dimerization in the plasma membrane using Forster resonance energy transfer.  Biophysical Journal.  558A-558A.
  • Sahalov H, O’Brien B, Stebe KJ, Hristova K, Searson P (2007).  Influence of applied potential on the impedance of alkanethiol SAMs.  Langmuir.  23(19).  9681-9685.
  • Chen L, Krishnamoothy G, Cui J, Sept D, Hristova K (2007).  Measuring the dimerization of FGFR3 transmembrane domain in cell membrane.  Biophysical Journal.  558A-558A.
  • He L, Li E, O’Connor S, Placone J, Hristova K (2007).  Studies of molecular mechanism of FGFR3 associated pathogenesis in cells.  Biophysical Journal.  558A-558A.
  • Merzlyakov M, Chen L, Li E, Hristova K (2007).  Quantitative FRET imaging of membrane protein interactions in cells.  Biophysical Journal.  558A-558A.
  • Searson P, Nikolov V, Merzlyakov M, Tomich J, Hristova K (2007).  Supported bilayers with functional ion channels.  Biophysical Journal.  251A-251A.
  • Soong R, Herrera A, Majumdar A, Tomich J, Hristova K (2007).  Towards high-resolution structure of FGFR3 transmembrane domains through H-1-H-1 NOESY and TOCSY NMR studies.  Biophysical Journal.  558A-558A.
  • O’Connor SK, He L, Li E, Betenbaugh M, Hristova K (2007).  Membrane protein expression in anti-apoptotic mammalian cells.  Biophysical Journal.  392A-392A.
  • Han X, Hristova K (2007).  Direct measurements of bilayer hydrocarbon core thickness in the presence of membrane proteins.  Biophysical Journal.  558A-558A.
  • You M, Spangler J, Li E, Han X, Ghosh P, Hristova K (2007).  Effect of pathogenic cysteine mutations on FGFR3 transmembrane domain dimerization in detergents and lipid bilayers.  Biochemistry.  46(39).  11039-11046.
  • Merzlyakov M, Li E, Gitsov I, Hristova K (2006).  Surface-supported bilayers with transmembrane proteins: Role of the polymer cushion revisited.  Langmuir.  22(24).  10145-10151.
  • Nikolov V, Radisic A, Hristova K, Searson PC (2006).  Bias-dependent admittance in hybrid bilayer membranes.  Langmuir.  22(17).  7156-7158.
  • Merzlyakov M, Li E, Casas R, Hristova K (2006).  Spectral Förster resonance energy transfer detection of protein interactions in surface-supported bilayers.  Langmuir.  22(16).  6986-6992.
  • Li E, Hristova K (2006).  Role of receptor tyrosine kinase transmembrane domains in cell signaling and human pathologies.  Biochemistry.  45(20).  6241-6251.
  • You M, Li E, Hristova K (2006).  The achondroplasia mutation does not alter the dimerization energetics of the fibroblast growth factor receptor 3 transmembrane domain.  Biochemistry.  45(17).  5551-5556.
  • Merzlyakov M, You M, Li E, Hristova K (2006).  Transmembrane helix heterodimerization in lipid bilayers: Probing the energetics behind autosomal dominant growth disorders.  Journal of Molecular Biology.  358(1).  1-7.
  • Li E, You M, Hristova K (2006).  FGFR3 dimer stabilization due to a single amino acid pathogenic mutation.  Journal of Molecular Biology.  356(3).  600-612.
  • Merzlyakov M, Li E, Hristova K (2006).  Directed assembly of surface-supported bilayers with transmembrane helices.  Langmuir.  22(3).  1247-1253.
  • Hristova K, Li E, Merzlyakov M (2006).  FGFR3 transmembrane domain dimerization in lipid bilayers: probing the energetics behind an autosomal dominant growth disorder.  Biochemistry and Cell Biology-Biochimie Et Biologie Cellulaire.  84(6).  1072-1072.
  • Han X, Mihailescu M, Hristova K (2006).  Neutron diffraction studies of fluid bilayers with transmembrane proteins: Structural consequences of the achondroplasia mutation.  Biophysical Journal.  91(10).  3736-3747.
  • Merzlyakov M, Li E, Hristova K (2006).  Directed assembly of surface-supported bilayers with transmembrane helices.  Langmuir.  22(3).  1247-1253.
  • Merzlyakov M, Li E, Casas R, Hristova K (2006).  Spectral Forster resonance energy transfer detection of protein interactions in surface-supported bilayers.  Langmuir.  22(16).  6986-6992.
  • Li E, You M, Hristova K (2006).  FGFR3 dimer stabilization due to a single amino acid pathogenic mutation.  Journal of Molecular Biology.  356(3).  600-612.
  • Merzlyakov M, Li E, Gitsov I, Hristova K (2006).  Surface-supported bilayers with transmembrane proteins: Role of the polymer cushion revisited.  Langmuir.  22(24).  10145-10151.
  • Han X, Mihailescu M, Hristova K (2006).  Neutron diffraction studies of fluid bilayers with transmembrane proteins: Structural consequences of the achondroplasia mutation.  Biophysical Journal.  91(10).  3736-3747.
  • Li E, Hristova K (2006).  Role of receptor tyrosine kinase transmembrane domains in cell signaling and human pathologies.  Biochemistry.  45(20).  6241-6251.
  • Hristova K (2006).  PHYS 60-Probing membrane protein interactions in surface supported bilayers.  Abstracts of Papers of the American Chemical Society.  232.
  • Li E, Hristova K, Merzlyakov M (2006).  COLL 583-Energetics of receptor tyrosine kinase dimerization.  Abstracts of Papers of the American Chemical Society.  232.
  • Merzlyakov M, You M, Li E, Hristova K (2006).  Transmembrane helix heterodimerization in lipid bilayers: Probing the energetics behind autosomal dominant growth disorders.  Journal of Molecular Biology.  358(1).  1-7.
  • Nikolov V, Radisic A, Hristova K, Searson P (2006).  Bias-dependent admittance in hybrid bilayer membranes.  Langmuir.  22(17).  7156-7158.
  • You M, Li E, Hristova K (2006).  The achondroplasia mutation does not alter the dimerization energetics of the fibroblast growth factor receptor 3 transmembrane domain.  Biochemistry.  45(17).  5551-5556.
  • Hristova K, White SH (2005).  An experiment-based algorithm for predicting the partitioning of unfolded peptides into phosphatidylcholine bilayer interfaces.  Biochemistry.  44(37).  12614-12619.
  • You M, Li E, Wimley WC, Hristova K (2005).  Förster resonance energy transfer in liposomes: Measurements of transmembrane helix dimerization in the native bilayer environment.  Analytical Biochemistry.  340(1).  154-164.
  • Iwamoto T, You M, Li E, Spangler J, Tomich JM, Hristova K (2005).  Synthesis and initial characterization of FGFR3 transmembrane domain: Consequences of sequence modifications.  Biochimica et Biophysica Acta - Biomembranes.  1668(2).  240-247.
  • Li E, You M, Hristova K (2005).  Sodium dodecyl sulfate-polyacrylamide gel electrophoresis and förster resonance energy transfer suggest weak interactions between fibroblast growth factor receptor 3 (FGFR3) transmembrane domains in the absence of extracellular domains and ligands.  Biochemistry.  44(1).  352-360.
  • Hristova K, Merzlyakov M, Li E (2005).  Probing membrane protein dimerization in supported lipid bilayers.  Abstracts of Papers of the American Chemical Society.  229.  U632-U632.
  • Li E, You M, Hristova K (2005).  Sodium dodecyl sulfate - Polyacrylamide gel electrophoresis and Forster resonance energy transfer suggest weak interactions between fibroblast growth factor receptor 3 (FGFR3) transmembrane domains in the absence of extracellular domains and ligands.  Biochemistry.  44(1).  352-360.
  • Iwamoto T, You M, Li E, Spangler J, Tomich JM, Hristova K (2005).  Synthesis and initial characterization of FGFR3 transmembrane domain: consequences of sequence modifications.  Biochimica Et Biophysica Acta-Biomembranes.  1668(2).  240-247.
  • You M, Li E, Wimley WC, Hristova K (2005).  Forster resonance energy transfer in liposomes: Measurements of transmembrane helix dimerization in the native bilayer environment.  Analytical Biochemistry.  340(1).  154-164.
  • Hristova K, White SH (2005).  An experiment-based algorithm for predicting the partitioning of unfolded peptides into phosphatidylcholine bilayer interfaces.  Biochemistry.  44(37).  12614-12619.
  • Li E, Hristova K (2004).  Imaging forster resonance energy transfer measurements of transmembrane helix interactions in lipid bilayers on a solid support.  Langmuir.  20(21).  9053-9060.
  • Li E, You M, Hristova K (2004).  Measurements of transmembrane helix dimerization in lipid bilayer environments.  Biophysical Journal.  86(1).  375A-375A.
  • Li E, Hristova K (2004).  Imaging forster resonance energy transfer measurements of transmembrane helix interactions in lipid bilayers on a solid support.  Langmuir.  20(21).  9053-9060.
  • Li EW, Gallagher G, Werbin J, You M, Hristova K (2003).  Mimicking transmembrane signaling events.  Biophysical Journal.  84(2).  294A-294A.
  • White SH, Hristova K, Tobias DJ (2002).  Determination of dynamic 3D structures of membranes from 1D data: Molecular dynamics/absolute scale refinement (MoDAS).  Abstracts of Papers American Chemical Society.  224(1-2).  35-PHYS 35.
  • Jayasinghe S, Hristova K, White SH (2001).  Energetics, stability, and prediction of transmembrane helices.  Journal of Molecular Biology.  312(5).  927-934.
  • Jayasinghe S, Hristova K, White SH (2001).  MPtopo: A database of membrane protein topology.  Protein Science.  10(2).  455-458.
  • Jayasinghe S, Hristova K, White SH (2001).  MPtopo: A database of membrane protein topology.  Protein Science.  10(2).  455-458.
  • Hristova K, Dempsey CE, White SH (2001).  Structure, location, and lipid perturbations of melittin at the membrane interface.  Biophysical Journal.  80(2).  801-811.
  • Hristova K, Dempsey CE, White SH (2001).  Structure, location, and lipid perturbations of melittin at the membrane interface.  Biophysical Journal.  80(2).  801-811.
  • Jayasinghe S, Hristova K, White SH (2001).  Energetics, stability, and prediction of transmembrane helices.  Journal of Molecular Biology.  312(5).  927-934.
  • White SH, Ladokhin AS, Jayasinghe S, Hristova K (2001).  How membranes shape protein structure.  Journal of Biological Chemistry.  276(35).  32395-32398.
  • Hristova K, White SH (2001).  Effect of lipid headgroups on peptide partitioning into bilayer interfaces.  Biophysical Journal.  80(1).  544A-544A.
  • Hristova K, White SH (2000).  Complete structure of dioleoylphosphatidylcholine (DOPC) bilayers as a function of hydration.  Biophysical Journal.  78(1).  21A-21A.
  • Hristova K, White SH (2000).  Free energies of transfer of C- and N-termini of peptides into octanol and POPC bilayers: An appendix to the first experimentally determined hydrophobicity scales.  Biophysical Journal.  78(1).  14A-14A.
  • Jayasinghe S, Hristova K, White SH (2000).  MPEx & MPtopo: Tools for membrane protein topology analysis.  Biophysical Journal.  78(1).  158A-158A.
  • Hristova K, Wimley WC, Mishra VK, Anantharamiah GM, Segrest JP, White SH (1999).  An amphipathic α-helix at a membrane interface: A structural study using a novel X-ray diffraction method.  Journal of Molecular Biology.  290(1).  99-117.
  • Anantharamiah GM, Hristova K, Mishra VK, Segrest JP, White SH, Wimley WC (1999).  An amphipathic alpha-helix at a membrane interface: A structural study using a novel X-ray diffraction method.  Journal of Molecular Biology.  290(1).  99-117.
  • Hristova K, White SH (1999).  Disposition of melittin in fluid lipid bilayers determined by x-ray diffraction.  Biophysical Journal.  76(1).  A219-A219.
  • Wimley WC, Hristova K, Ladokhin AS, Silvestro L, Axelsen PH, White SH (1998).  Folding of β-sheet membrane proteins: A hydrophobic hexapeptide model.  Journal of Molecular Biology.  277(5).  1091-1110.
  • Hristova K, Ladokhin A, White SH, Wimley WC (1998).  Protein folding in membranes: Pondering the nature of the bilayer milieu.  Kongelige Danske Videnskabernes Selskab Biologiske Skrifter.  49(0).  99-106.
  • White SH, Wimley WC, Ladokhin AS, Hristova K (1998).  Protein folding in membranes: Determining energetics of peptide-bilayer interactions.  Methods in Enzymology.  295.  62-87.
  • Hristova K, White SH (1998).  Determination of the hydrocarbon core structure of fluid dioleoylphosphocholine (DOPC) bilayers by x-ray diffraction using specific bromination of the double-bonds: Effect of hydration.  Biophysical Journal.  74(5).  2419-2433.
  • Hristova K, White SH (1998).  Determination of the hydrocarbon core structure of fluid dioleoylphosphocholine (DOPC) bilayers by x-ray diffraction using specific bromination of the double-bonds: Effect of hydration.  Biophysical Journal.  74(5).  2419-2433.
  • Hristova K, Selsted ME, White SH (1997).  Critical role of lipid composition in membrane permeabilization by rabbit neutrophil defensins.  Journal of Biological Chemistry.  272(39).  24224-24233.
  • Ladokhin AS, Wimley WC, Hristova K, White SH (1997).  Mechanism of leakage of contents of membrane vesicles determined by fluorescence requenching.  Methods in Enzymology.  278.  474-486.
  • Hristova K, Selsted ME, White SH (1997).  Critical role of lipid composition in membrane permeabilization by rabbit neutrophil defensins.  Journal of Biological Chemistry.  272(39).  24224-24233.
  • Hristova K, Selsted ME, White SH (1996).  Interactions of monomeric rabbit neutrophil defensins with bilayers: Comparison with dimeric human defensin HNP-2.  Biochemistry.  35(36).  11888-11894.
  • Hristova K, Selsted ME, White SH (1996).  Interactions of monomeric rabbit neutrophil defensins with bilayers: Comparison with dimeric human defensin HNP-2.  Biochemistry.  35(36).  11888-11894.
  • Hristova K, Kenworthy A, McIntosh TJ (1995).  Effect of Bilayer Composition on the Phase Behavior of Liposomal Suspensions Containing Polyethylene glycol)–Lipids.  Macromolecules.  28(23).  7693-7699.
  • Hristova K, Needham D (1995).  Phase Behavior of a Lipid/Polymer-Lipid Mixture in Aqueous Medium.  Macromolecules.  28(4).  991-1002.
  • Hristova K, Needham D (1995).  Influence of bilayer fluctuations on the steric interactions between polymer-grafted bilayers.  Liquid Crystals.  18(3).  423-430.
  • Kenworthy AK, Hristova K, Needham D, McIntosh TJ (1995).  Range and magnitude of the steric pressure between bilayers containing phospholipids with covalently attached poly(ethylene glycol).  Biophysical Journal.  68(5).  1921-1936.
  • Hristova K, Needham D (1994).  The Influence of polymer-grafted lipids on the physical properties of lipid bilayers: A theoretical study.  Journal of Colloid And Interface Science.  168(2).  302-314.
  • Petrov AG, Miller BA, Hristova K, Usherwood PNR (1993).  Flexoelectric effects in model and native membranes containing ion channels.  European Biophysics Journal.  22(4).  289-300.
  • Hristova K, Miller BA, Petrov AG, Usherwood PN (1993).  FLEXOELECTRIC EFFECTS IN MODEL AND NATIVE MEMBRANES CONTAINING ION CHANNELS.  European Biophysics Journal with Biophysics Letters.  22(4).  289-300.
  • Hristova K, Bivas I, Derzhanski A (1992).  Frequency dependence of the membrane flexoelectric voltage response. Adsorption of multivalent counterions on the surface of curved lipid bilayer.  Molecular Crystals and Liquid Crystals Science and Technology. Section A. Molecular Crystals and Liquid Crystals.  215(1).  237-244.
  • Needham D, Hristova K, Mcintosh TJ, Dewhirst M, Wu N, Lasic DD (1992).  Polymer-grafted liposomes: Physical basis for the "stealth" property.  Journal of Liposome Research.  2(3).  411-430.
  • Bivas I, Hristova K (1991).  The electric part of the curvature elasticity of a membrane and its relation to flexoelectricity.  Liquid Crystals.  9(6).  883-892.
  • Derzhanski A, Petrov AG, Todorov AT, Hristova K (1990).  Flexoelectricity of lipid bilayers.  Liquid Crystals.  7(3).  439-449.
Books
  • Lin J, Hristova K, Searson P (2013).  Electrically Addressable, Biologically Relevant Surface-Supported Bilayers.  769-820.
Book Chapters
  • He L, Hristova K (2014).  Quantification of the effects of mutations on receptor tyrosine kinase (RTK) activation in mammalian cells.  Receptor Tyrosine Kinases: Methods and Protocols.  81-87.
  • Lin J, Hristova K, Searson PC (2013).  Electrically addressable, biologically relevant surface-supported bilayers.  Handbook of Biofunctional Surfaces.  769-820.
  • Merzlyakov M, Hristova K (2008).  FORSTER RESONANCE ENERGY TRANSFER MEASUREMENTS OF TRANSMEMBRANE HELIX DIMERIZATION ENERGETICS.  Fluorescence Spectroscopy.  450.  107-127.
  • Hristova K, Ladokhin AS, White SH, Wimley WC (1998).  Protein folding in membranes: Determining energetics of peptide-bilayer interactions.  Methods in Enzymology; Energetics of biological macromolecules, Part B.  295.  62-87.
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