Chen, Yun

Assistant Professor
Mechanical Engineering

Latrobe Hall 219
yun.chen@jhu.edu

Jump to:

About

Experience
  • 2015 - Present:  Faculty Member of Center for Cell Dynamics, SOM School of Medicine
Presentations
  • "A microtissue-building toolbox to study biophysical effects on cell dynamics", 2017 ASCB/EMBO meeting.  Philadelphia Pennsylvania, United States of America (the).  December 3, 2017
  • "Multidisciplinary Research Career Development", Boston Taiwanese Biotechnology Association (BTBA) symposium.  Cambrudge Massachusetts, United States of America (the).  August 5, 2017
  • "Environmental Adaptation at The Multi-Cellular Level", NSF Quantitative Cell Biology workshop: Cells as Dynamical Systems.  San Francisco California, United States of America (the).  May 22, 2017
  • "Building an Imaging-Based Toolbox to Study Mechnochemistry", Seminar Series of the Patent Examiner Technical Training Program.  Alexandria Virginia, United States of America (the).  April 25, 2017
  • "3D bio-printing organoids of physiological geometry at micron resolution", Biology Department Seminar.  Clinton New York, United States of America (the).  February 27, 2017
  • "Developing 3D Molding Technique to Study the Effect of Geometry on Protein Expression", American Society of Cell Biology 2016 Annual Meeting.  San Francisco, United States of America (the).  December 4, 2016
  • "Imaging Organoids", National Cancer Institute Department Seminar.  Frederick Maryland, United States of America (the).  August 24, 2016

Publications

Journal Articles
  • Chen Y, Oleg Milberg, Akiko Shitara, Andrius Masedunskas, Duy T. Tran,, Mary Anne Conti, Robert S. Adelstein, Kelly G. Ten Hagen, Roberto Weigert (2017).  Concerted actions of distinct nonmuscle myosin II isoforms drive intracellular membrane remodeling in live animals.  Journal of Cell Biology.  216(7).  1925.
  • Masedunskas A, Chen Y, Stussman R, Weigert R, Mather IH (2017).  Kinetics of milk lipid droplet transport, growth, and secretion revealed by intravital imaging: lipid droplet release is intermittently stimulated by oxytocin..  Molecular biology of the cell.  28(7).  935-946.
  • Rosenberg AZ, Armani MD, Fetsch PA, Xi L, Pham TT, Raffeld M, Chen Y, O'Flaherty N, Stussman R, Blackler AR, Du Q, Hanson JC, Roth MJ, Filie AC, Roh MH, Emmert-Buck MR, Hipp JD, Tangrea MA (2016).  High-Throughput Microdissection for Next-Generation Sequencing..  PloS one.  11(3).  e0151775.
  • Tangrea MA, Rosenberg AZ, Fetsch PA, Armani MD, Xi L, Raffeld M, Pham TT, Chen Y, O’Flaherty N, Stussman R, others (2015).  Do-It-Yourself expression microdissection (DIY xMD): A low-cost, high-throughput cell and organelle isolation system.  Cancer Research.  75(15 Supplement).  230-230.
  • Porat-Shliom N, Chen Y, Tora M, Shitara A, Masedunskas A, Weigert R (2014).  In vivo tissue-wide synchronization of mitochondrial metabolic oscillations.  Cell reports.  9(2).  514-521.
  • Chen Y, Tangrea MA, Rosenberg AZ, Du Q, Emmert-Buck MA (2014).  Diffusion Discrepancy between Stroma of Tumor and Normal Tissues.  Biophysical Journal.  106(2).  734a.
  • Qian C, Yu X, Chen D, Dodd S, Bouraoud N, Pothayee N, Chen Y, Beeman S, Bennett K, Murphy-Boesch J, others (2013).  Wireless amplified nuclear MR detector (WAND) for high-spatial-resolution MR imaging of internal organs: preclinical demonstration in a rodent model.  Radiology.  268(1).  228-236.
  • Chen Y, Dodd SJ, Tangrea MA, Emmert-Buck MR, Koretsky AP (2013).  Measuring collective cell movement and extracellular matrix interactions using magnetic resonance imaging.  Scientific reports.  3.
  • Chen Y, Pasapera AM, Koretsky AP, Waterman CM (2013).  Orientation-specific responses to sustained uniaxial stretching in focal adhesion growth and turnover.  Proceedings of the National Academy of Sciences.  110(26).  E2352-E2361.
  • Chen Y, Guzik S, Sumner JP, Moreland J, Koretsky AP (2011).  Magnetic manipulation of actin orientation, polymerization, and gliding on myosin using superparamagnetic iron oxide particles.  Nanotechnology.  22(6).  065101.
  • Chen Y, Veracini L, Benistant C, Jacobson K (2009).  The transmembrane protein CBP plays a role in transiently anchoring small clusters of Thy-1, a GPI-anchored protein, to the cytoskeleton.  Journal of cell science.  122(21).  3966-3972.
  • Thelin WR, Chen Y, Gentzsch M, Kreda SM, Sallee JL, Scarlett CO, Borchers CH, Jacobson K, Stutts MJ, Milgram SL (2007).  Direct interaction with filamins modulates the stability and plasma membrane expression of CFTR.  Journal of Clinical Investigation.  117(2).  364.
  • Chen Y, Lagerholm BC, Yang B, Jacobson K (2006).  Methods to measure the lateral diffusion of membrane lipids and proteins.  Methods.  39(2).  147-153.
  • Chen Y, Thelin WR, Yang B, Milgram SL, Jacobson K (2006).  Transient anchorage of cross-linked glycosyl-phosphatidylinositol-anchored proteins depends on cholesterol, Src family kinases, caveolin, and phosphoinositides.  The Journal of cell biology.  175(1).  169-178.
  • Chen Y, Yang B, Jacobson K (2004).  Transient confinement zones: a type of lipid raft?.  Lipids.  39(11).  1115-1119.
  • Peterson LJ, Rajfur Z, Maddox AS, Freel CD, Chen Y, Edlund M, Otey C, Burridge K (2004).  Simultaneous stretching and contraction of stress fibers in vivo.  Molecular biology of the cell.  15(7).  3497-3508.
  • Chen Y, Lai M (2001).  c-Jun NH2-terminal kinase activation leads to a FADD-dependent but Fas ligand-independent cell death in Jurkat T cells.  Journal of Biological Chemistry.  276(11).  8350-8357.
Back to top