Barta, Patrick

Adjunct Associate Research Scientist
Biomedical Engineering

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  • Doctor of Medicine 1985, The Johns Hopkins University
  • Ph.D. 1985, School of Medicine
  • 2003 - Present:  Joint, SOM Psychiatry and Behavioral Sciences
  • 2002 - 2003:  Associate Professor, SOM Biomedical Engineering
Research Areas
  • Cortical manifestations of schizophrenia
  • MRI Data Processing
  • Measure
  • Measuring things in volume data
  • Neuroanatomy of schizophrenia
  • RF field inhomogeneity
  • RF field segmentation
  • RF field warping
  • Schizophrenia
  • Stereological techniques
  • Volume data
  • 1978:  Tau Beta Pi
  • 1977:  Phi Beta Kappa


Journal Articles
  • Mahon PB, Lee DS, Trinh H, Tward D, Miller MI, Younes L, Barta PE, Ratnanather JT (2015).  Morphometry of the amygdala in schizophrenia and psychotic bipolar disorder.  Schizophrenia Research.  164(1-3).
  • Ratnanather JT, Cebron S, Ceyhan E, Postell E, Pisano DV, Poynton CB, Crocker B, Honeycutt NA, Mahon PB, Barta PE (2014).  Morphometric differences in planum temporale in schizophrenia and bipolar disorder revealed by statistical analysis of labeled cortical depth maps.  Frontiers in Psychiatry.  5(AUG).
  • Takayanagi M, Wentz J, Takayanagi Y, Schretlen DJ, Ceyhan E, Wang L, Suzuki M, Sawa A, Barta PE, Ratnanather JT, Cascella NG (2013).  Reduced anterior cingulate gray matter volume and thickness in subjects with deficit schizophrenia.  Schizophrenia Research.  150(2-3).
  • Ratnanather JT, Poynton CB, Pisano DV, Crocker B, Postell E, Cebron S, Ceyhan E, Honeycutt NA, Mahon PB, Barta PE (2013).  Morphometry of superior temporal gyrus and planum temporale in schizophrenia and psychotic bipolar disorder.  Schizophrenia Research.  150(2-3).
  • Mahon PB, Eldridge H, Crocker B, Notes L, Gindes H, Postell E, King S, Potash JB, Ratnanather JT, Barta PE (2012).  An MRI study of amygdala in schizophrenia and psychotic bipolar disorder.  Schizophrenia Research.  138(2-3).
  • Qiu A, Vaillant M, Barta P, Ratnanather JT, Miller MI (2008).  Region-of-interest-based analysis with application of cortical thickness variation of left planum temporale in schizophrenia and psychotic bipolar disorder.  Human Brain Mapping.  29(8).
  • QIU A, VAILLANT M, Barta P, RATNANATHER J, MILLER M (2008).  Region-of-interest-based analysis with application of cortical thickness variation of left planum temporale in schizophrenia and psychotic bipolar disorder.  Human Brain Mapping.  29(8).  973-985.
  • Qiu A, Rosenau BJ, Greenberg AS, Hurdal MK, Barta P, Yantis S, Miller MI (2006).  Estimating linear cortical magnification in human primary visual cortex via dynamic programming.  NeuroImage.  31(1).
  • Khan A, Aylward E, Barta P, Miller M, Beg MF (2005).  Semi-automated basal ganglia segmentation using large deformation diffeomorphic metric mapping.  Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics).  3749 LNCS.
  • Qiu A, Rosenau BJ, Greenberg AS, Barta P, Yantis S, Miller MI (2005).  Localizing retinotopic fMRI activation in human primary visual cortex via dynamic programming.  Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings.  7 VOLS.
  • Barta P, Miller MI, Qiu A (2005).  A stochastic model for studying the laminar structure of cortex from MRI.  IEEE Transactions on Medical Imaging.  24(6).
  • Strasser HC, Lilyestrom J, Ashby ER, Honeycutt NA, Schretlen DJ, Pulver AE, Hopkins RO, Depaulo JR, Potash JB, Schweizer B, Yates KO, Kurian E, Barta PE, Pearlson GD (2005).  Hippocampal and ventricular volumes in psychotic and nonpsychotic bipolar patients compared with schizophrenia patients and community control subjects: A pilot study.  Biological Psychiatry.  57(6).
  • Khan A, Aylward E, Barta P, Miller M, Beg MF (2005).  Semi-automated basal ganglia segmentation using large deformation diffeomorphic metric mapping..  Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention.  8(Pt 1).
  • Buchanan RW, Francis A, Arango C, Miller K, Lefkowitz DM, McMahon RP, Barta PE, Pearlson GD (2004).  Morphometric Assessment of the Heteromodal Association Cortex in Schizophrenia.  American Journal of Psychiatry.  161(2).
  • Ratnanather JT, Barta PE, Honeycutt NA, Lee N, Morris HM, Dziorny AC, Hurdal MK, Pearlson GD, Miller MI (2003).  Dynamic programming generation of boundaries of local coordinatized submanifolds in the neocortex: Application to the planum temporale.  NeuroImage.  20(1).
  • Barta P, Dazzan P (2003).  Hemispheric surface area: Sex, laterality and age effects.  Cerebral Cortex.  13(4).
  • Rivkin P, Kraut M, Barta P, Anthony J, Arria AM, Pearlson G (2000).  White matter hyperintensity volume in late-onset and early-onset schizophrenia.  International Journal of Geriatric Psychiatry.  15(12).
  • Aylward EH, Codori AM, Rosenblatt A, Sherr M, Brandt J, Stine OC, Barta PE, Pearlson GD, Ross CA (2000).  Rate of caudate atrophy in presymptomatic and symptomatic stages of Huntington's disease.  Movement Disorders.  15(3).
  • Honeycutt NA, Musick A, Barta PE, Pearlson GD (2000).  Measurement of the planum temporale (PT) on magnetic resonance imaging scans: Temporal PT alone and with parietal extension.  Psychiatry Research - Neuroimaging.  98(2).
  • Frederikse M, Lu A, Aylward E, Barta P, Sharma T, Pearlson G (2000).  Sex differences in inferior parietal lobule volume in schizophrenia.  American Journal of Psychiatry.  157(3).
  • Schretlen D, Pearlson GD, Anthony JC, Aylward EH, Augustine AM, Davis A, Barta P (2000).  Elucidating the contributions of processing speed, executive ability, and frontal lobe volume to normal age-related differences in fluid intelligence.  Journal of the International Neuropsychological Society.  6(1).
  • Aylward EH, Minshew NJ, Goldstein G, Honeycutt NA, Augustine AM, Yates KO, Barta PE, Pearlson GD (1999).  MRI volumes of amygdala and hippocampus in non-mentally retarded autistic adolescents and adults.  Neurology.  53(9).
  • Frederikse ME, Lu A, Aylward E, Barta P, Pearlson G (1999).  Sex differences in the inferior parietal lobule.  Cerebral Cortex.  9(8).
  • Sharma T, Lancaster E, Sigmundsson T, Lewis S, Takei N, Gurling H, Barta P, Pearlson G, Murray R (1999).  Lack of normal pattern of cerebral asymmetry in familial schizophrenic patients and their relatives - The Maudsley Family Study.  Schizophrenia Research.  40(2).
  • Aylward EH, Li Q, Honeycutt NA, Warren AC, Pulsifer MB, Barta PE, Chan MD, Smith PD, Jerram M, Pearlson GD (1999).  MRI volumes of the hippocampus and amygdala in adults with Down's syndrome with and without dementia.  American Journal of Psychiatry.  156(4).
  • Honeycutt NA, Smith PD, Aylward E, Li Q, Chan M, Barta PE, Pearlson GD (1998).  Mesial temporal lobe measurements on magnetic resonance imaging scans.  Psychiatry Research - Neuroimaging.  83(2).
  • Sharma T, Lancaster E, Lee D, Lewis S, Sigmundsson T, Takei N, Gurling H, Barta P, Pearlson G, Murray R (1998).  Brain changes in schizophrenia. Volumetric MRI study of families multiply affected with schizophrenia - The Maudsley Family Study 5.  British Journal of Psychiatry.  173(AUG.).
  • Pearlson GD, Breiter SN, Aylward EH, Warren AC, Grygorcewicz M, Frangou S, Barta PE, Pulsifer MB (1998).  MRI brain changes in subjects with Down syndrome with and without dementia.  Developmental Medicine and Child Neurology.  40(5).
  • Aylward EH, Anderson NB, Bylsma FW, Wagster MV, Barta PE, Sherr M, Feeney J, Davis A, Rosenblatt A, Pearlson GD, Ross CA (1998).  Frontal lobe volume in patients with Huntington's disease.  Neurology.  50(1).
  • Buchanan RW, Vladar K, Barta PE, Pearlson GD (1998).  Structural evaluation of the prefrontal cortex in schizophrenia.  American Journal of Psychiatry.  155(8).
  • Schlaepfer TE, Strain EC, Greenberg BD, Preston KL, Lancaster E, Bigelow GE, Barta PE, Pearlson GD (1998).  Site of opioid action in the human brain: Mu and kappa agonists' subjective and cerebral blood flow effects.  American Journal of Psychiatry.  155(4).
  • Barta PE, Dhingra L, Royall R, Schwartz E (1997).  Improving sterological estimates for the volume of structures identified in three-dimensional arrays of spatial data.  Journal of Neuroscience Methods.  75(2).
  • Aylward EH, Augustine A, Li Q, Barta PE, Pearlson GD (1997).  Measurement of frontal lobe volume on magnetic resonance imaging scans.  Psychiatry Research - Neuroimaging.  75(1).
  • Frangou S, Sharma T, Sigmudsson T, Barta P, Pearlson G, Murray RM (1997).  The Maudsley Family Study 4. Normal planum temporale asymmetry in familial schizophrenia. A volumetric MRI study.  British Journal of Psychiatry.  170(APR.).
  • Aylward EH, Li Q, Habbak R, Warren A, Pulsifer MB, Barta PE, Jerram M, Pearlson G (1997).  Basal ganglia volume in adults with Down syndrome.  Psychiatry Research - Neuroimaging.  74(2).
  • Barta PE, Powers RE, Aylward EH, Chase GA, Harris GJ, Rabins PV, Tune LE, Pearlson GD (1997).  Quantitative MRI volume changes in late onset schizophrenia and Alzheimer's disease compared to normal controls.  Psychiatry Research - Neuroimaging.  68(2-3).
  • Aylward EH, Li Q, Stine OC, Ranen N, Sherr M, Barta PE, Bylsma FW, Pearlson GD, Ross CA (1997).  Longitudinal change in basal ganglia volume in patients with Huntington's disease.  Neurology.  48(2).
  • Frangou S, Aylward E, Warren A, Sharma T, Barta P, Pearlson G (1997).  Small planum temporale volume in Down's syndrome: A volumetric MRI study.  American Journal of Psychiatry.  154(10).
  • Barta PE, Pearlson GD, Brill LB, Royall R, McGilchrist IK, Pulver AE, Powers RE, Casanova MF, Tien AY, Frangou S, Petty RG (1997).  Planum temporale asymmetry reversal in schizophrenia: Replication and relationship to gray matter abnormalities.  American Journal of Psychiatry.  154(5).
  • Aylward EH, Habbak R, Warren AC, Pulsifer MB, Barta PE, Jerram M, Pearlson GD (1997).  Cerebellar volume in adults with Down syndrome.  Archives of Neurology.  54(2).
  • Pearlson GD, Barta PE, Powers RE, Menon RR, Richards SS, Aylward EH, Federman EB, Chase GA, Petty RG, Tien AY (1997).  Medial and superior temporal gyral volumes and cerebral asymmetry in schizophrenia versus bipolar disorder.  Biological Psychiatry.  41(1).
  • Davison SE, Aylward EH, McArthur JC, Selnes OA, Lyketsos C, Barta PE, Pearlson GD (1996).  A quantitative MRI study of the basal ganglia in depression in HIV seropositive men.  Journal of Neuro-AIDS.  1(3).
  • Tune L, Barta P, Wong D, Powers RE, Pearlson G, Tien AY, Wagner HN (1996).  Striatal dopamine D2receptor quantification and superior temporal gyrus: Volume determination in 14 chronic schizophrenic subjects.  Psychiatry Research - Neuroimaging.  67(2).
  • Tien AY, Eaton WW, Schlaepfer TE, McGilchrist IK, Menon R, Powers R, Aylward E, Barta P, Strauss ME, Pearlson GD (1996).  Exploratory factor analysis of MRI brain structure measures in schizophrenia.  Schizophrenia Research.  19(2-3).
  • Harris GJ, Aylward EH, Peyser CE, Pearlson GD, Brandt J, Roberts-Twillie JV, Barta PE, Folstein SE (1996).  Single photon emission computed tomographic blood flow and magnetic resonance volume imaging of basal ganglia in Huntington's disease.  Archives of Neurology.  53(4).
  • Aylward EH, Harris GJ, Hoehn-Saric R, Barta PE, Machlin SR, Pearlson GD (1996).  Normal caudate nucleus in obsessive-compulsive disorder assessed by quantitative neuroimaging.  Archives of General Psychiatry.  53(7).
  • Aylward EH, Codori AM, Barta PE, Pearlson GD, Harris GJ, Brandt J (1996).  Basal ganglia volume and proximity to onset in presymptomatic Huntington disease.  Archives of Neurology.  53(12).
  • Noga JT, Aylward E, Barta PE, Pearlson GD (1995).  Cingulate gyrus in schizophrenic patients and normal volunteers.  Psychiatry Research: Neuroimaging.  61(4).
  • Barta PE, Petty RG, McGilchrist I, Lewis RW, Jerram M, Casanova MF, Powers RE, Brill LB, Pearlson GD (1995).  Asymmetry of the planum temporale: methodological considerations and clinical associations.  Psychiatry Research: Neuroimaging.  61(3).
  • Menon RR, Barta PE, Aylward EH, Richards SS, Vaughn DD, Tien AY, Harris GJ, Pearlson GD (1995).  Posterior superior temporal gyrus in schizophrenia: grey matter changes and clinical correlates.  Schizophrenia Research.  16(2).
  • Petty RG, Barta PE, Pearlson GD, McGilchrist IK, Lewis RW, Tien AY, Pulver A, Vaughn DD, Casanova MF, Powers RE (1995).  Reversal of asymmetry of the planum temporale in schizophrenia.  American Journal of Psychiatry.  152(5).
  • Aylward EH, Brettschneider PD, McArthur JC, Harris GJ, Schlaepfer TE, Henderer JD, Barta PE, Tien AY, Pearlson GD (1995).  Magnetic resonance imaging measurement of gray matter volume reductions in HIV dementia.  American Journal of Psychiatry.  152(7).
  • Aylward EH, Brandt J, Codori AM, Mangus RS, Barta PE, Harris GJ (1994).  Reduced basal ganglia volume associated with the gene for Huntington's disease in asymptomatic at-risk persons.  Neurology.  44(5).
  • Harris GJ, Barta PE, Peng LW, Lee S, Brettschneider PD, Shah A, Henderer JD, Schlaepfer TE, Pearlson GD (1994).  MR volume segmentation of gray matter and white matter using manual thresholding: Dependence on image brightness.  American Journal of Neuroradiology.  15(2).
  • Aylward EH, Roberts-Twillie JV, Barta PE, Kumar AJ, Harris GJ, Geer M, Peyser CE, Pearlson GD (1994).  Basal ganglia volumes and white matter hyperintensities in patients with bipolar disorder.  American Journal of Psychiatry.  151(5).
  • Schlaepfer TE, Harris GJ, Tien AY, Peng LW, Lee S, Federman EB, Chase GA, Barta PE, Pearlson GD (1994).  Decreased regional cortical gray matter volume in schizophrenia.  American Journal of Psychiatry.  151(6 SUPPL.).
  • Aylward EH, Reiss A, Barta PE, Tien A, Han W, Lee J, Pearlson GD (1994).  Magnetic resonance imaging measurement of posterior fossa structures in schizophrenia.  American Journal of Psychiatry.  151(10).
  • Pearlson GD, Tune LE, Wong DF, Aylward EH, Barta PE, Powers RE, Tien AY, Chase GA, Harris GJ, Rabins PV (1993).  Quantitative D2dopamine receptor PET and structural MRI changes in late-onset schizophrenia.  Schizophrenia Bulletin.  19(4).
  • Aylward EH, Henderer JD, Mcarthur JC, Brettschneider PD, Harris GJ, Barta PE, Pearlson GD (1993).  Reduced basal ganglia volume in hiv-1-associated dementia: Results from quantitative neuroimaging.  Neurology.  43(10).
  • Pearlson GD, Geer MJ, Barta PE, Chilcoat HD (1993).  A computerized magnetic resonance imaging study of corpus callosum morphology in schizophrenia.  Psychological Medicine.  23(1).
  • Piven J, Nehme E, Simon J, Barta P, Pearlson G, Folstein SE (1992).  Magnetic resonance imaging in autism: measurement of the cerebellum, pons, and fourth ventricle.  Biological Psychiatry.  31(5).
  • Schwartz JM, Aylward E, Barta PE, Tune LE, Pearlson GD (1992).  Sylvian fissure size in schizophrenia measured with the magnetic resonance imaging rating protocol of the Consortium to Establish a Registry for Alzheimer's Disease.  American Journal of Psychiatry.  149(9).
  • Harris GJ, Pearlson GD, Peyser CE, Aylward EH, Roberts J, Barta PE, Chase GA, Folstein SE (1992).  Putamen volume reduction on magnetic resonance imaging exceeds caudate changes in mild Huntington's disease.  Annals of Neurology.  31(1).
  • Pearlson GD, Harris GJ, Powers RE, Barta PE, Camargo EE, Chase GA, Noga JT, Tune LE (1992).  Quantitative Changes in Mesial Temporal Volume, Regional Cerebral Blood Flow, and Cognition in Alzheimer's Disease.  Archives of General Psychiatry.  49(5).
  • Barta PE, Pearlson GD, Powers RE, Richards SS, Tune LE (1990).  Auditory hallucinations and smaller superior temporal gyral volume in schizophrenia.  American Journal of Psychiatry.  147(11).
  • Barta P, Barta W (1988).  DISPO advisor - expert system for psychiatric disposition.  Proceedings - Annual Symposium on Computer Applications in Medical Care.
  • Miller MI, Barta PE, Sachs B (1987).  Strategies for the representation of a tone in background noise in the temporal aspects of the discharge patterns of auditory-nerve fibers.  Journal of the Acoustical Society of America.  81(3).
  • Young ED, Barta PE (1986).  Rate responses of auditory nerve fibers to tones in noise near masked threshold.  Journal of the Acoustical Society of America.  79(2).
  • Schneider M, Tolchin SG, Kahane SN, Goldberg HS, Barta P (1985).  WORKSTATION-BASED INPATIENT CLINICAL SYSTEM IN THE JOHNS HOPKINS HOSPITAL..  Proceedings - Annual Symposium on Computer Applications in Medical Care.
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