Develop high resolution real-time Spectral Domain optical coherence tomography for the early and precise detection of traumatic brain injury
To develop high resolution real-time Spectral Domain optical coherence tomography for the early and precise detection of traumatic brain injury. Traumatic brain injury (TBI), a form of acquired brain injury, occurs when a sudden trauma causes damage to the brain. TBI can result when the head suddenly and violently hits an object, or when an object pierces the skull and enters brain tissue. Symptoms of a TBI can be mild, moderate, or severe, depending on the extent of the damage to the brain. Anyone with signs of moderate or severe TBI should receive medical attention as soon as possible. Because little can be done to reverse the initial brain damage caused by trauma, medical personnel try to stabilize an individual with TBI and focus on preventing further injury. In this study, we will use OCT to investigate the retina variation of the mouse induced by specific brain injury model. The goal is to diagnose the signs of brain injury as soon as possible since retina is directly related to the brain.