{"id":15612,"date":"2017-10-17T11:40:30","date_gmt":"2017-10-17T15:40:30","guid":{"rendered":"https:\/\/engineering.jhu.edu\/chembe\/?p=15612"},"modified":"2021-12-02T14:13:35","modified_gmt":"2021-12-02T19:13:35","slug":"keeping-antibodies-pure-costs","status":"publish","type":"news","link":"https:\/\/engineering.jhu.edu\/chembe\/news\/keeping-antibodies-pure-costs\/","title":{"rendered":"Keeping antibodies pure and costs down"},"content":{"rendered":"

Third-year PhD candidate Yi Li<\/strong> is planning a career as an industrial research scientist because she wants to help create new products to treat cancer. In her ChemBE lab, she\u2019s laying the foundation for that future by working on an antibody purification project using self-assembling peptide nanofibers.<\/p>\n

Li, a native of China\u2019s Shandong province who earned her bachelor\u2019s degree in chemical engineering at Tsinghua University in Beijing, was attracted to Johns Hopkins by its strengths in chemical and biological research. Until recently, her lab has focused on the role of peptide nanofibers in cancer drug delivery, and her project represents a new application of peptide nanofibers. Many cancer drugs rely on monoclonal antibodies, but the current method of purifying them\u2014using affinity chromatography\u2014is prohibitively expensive. Her group hopes to reduce the costs of purification and ease the process without affecting the antibodies\u2019 bioactivity.<\/p>\n

\u201cIn the lab, we design the chemical structure of the peptide conjugates,\u201d Li says. \u201cThrough the design, we can partly control the morphology of the self-assembling nanostructures.\u201d<\/p>\n

Li says her experiences in the department have given her the confidence to face and address challenges in both research and life, which she expects to follow her through her PhD and beyond.<\/p>\n

Outside of the lab, Li enjoys traveling, cooking, and spending time with friends. She appreciates the smiles and greetings she exchanges with passersby in the U.S. \u201cPeople here are so outgoing,\u201d she notes.<\/p>\n","protected":false},"template":"","class_list":["post-15612","news","type-news","status-publish","hentry","news_categories-research"],"acf":[],"yoast_head":"\nKeeping antibodies pure and costs down - Department of Chemical and Biomolecular Engineering<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/engineering.jhu.edu\/chembe\/news\/keeping-antibodies-pure-costs\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Keeping antibodies pure and costs down - Department of Chemical and Biomolecular Engineering\" \/>\n<meta property=\"og:description\" content=\"Third-year PhD candidate Yi Li is planning a career as an industrial research scientist because she wants to help create new products to treat cancer. In her ChemBE lab, she\u2019s…\" \/>\n<meta property=\"og:url\" content=\"https:\/\/engineering.jhu.edu\/chembe\/news\/keeping-antibodies-pure-costs\/\" \/>\n<meta property=\"og:site_name\" content=\"Department of Chemical and Biomolecular Engineering\" \/>\n<meta property=\"article:modified_time\" content=\"2021-12-02T19:13:35+00:00\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"1 minute\" \/>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Keeping antibodies pure and costs down - Department of Chemical and Biomolecular Engineering","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/engineering.jhu.edu\/chembe\/news\/keeping-antibodies-pure-costs\/","og_locale":"en_US","og_type":"article","og_title":"Keeping antibodies pure and costs down - Department of Chemical and Biomolecular Engineering","og_description":"Third-year PhD candidate Yi Li is planning a career as an industrial research scientist because she wants to help create new products to treat cancer. 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