{"id":55401,"date":"2026-01-14T10:00:00","date_gmt":"2026-01-14T15:00:00","guid":{"rendered":"https:\/\/engineering.jhu.edu\/ams\/?post_type=tribe_events&p=55401"},"modified":"2026-01-14T10:00:00","modified_gmt":"2026-01-14T15:00:00","slug":"ams-special-seminar-series-alan-amin","status":"publish","type":"tribe_events","link":"https:\/\/engineering.jhu.edu\/ams\/event\/ams-special-seminar-series-alan-amin\/","title":{"rendered":"AMS Special Seminar Series | Alan Amin"},"content":{"rendered":"

Location: <\/strong>Shaffer 3<\/p>\n

When:<\/strong> January 22nd at 1:30 p.m.<\/p>\n

Title:<\/strong> Machine Learning for Nature’s Overlooked Experiments<\/p>\n

Abstract: <\/strong><\/span>Large-scale efforts have amassed vast biological sequence data, enabling machine learning models to learn conserved motifs and advance protein engineering. Yet in many high-impact domains\u2014shrinking proteins for therapeutic delivery, engineering antibodies for diverse targets, incorporating priors into underpowered genetic studies\u2014practitioners still resort to mining homologues, starting from scratch, or using simple linear models. The barrier is not data scarcity but that models trained on canonical evolutionary signals fail when the relevant information lies elsewhere. My work demonstrates that large-scale biological data can be leveraged for these problems given the appropriate statistical and computational framework: learning how nature navigates combinatorial deletion space to build smaller proteins, how our immune systems optimize antibodies, and how flexible models can scale to massive genetic datasets without overfitting.<\/p>\n

Bio:<\/strong> Alan is a faculty fellow at the Courant Institute at New York University, working with the Wilson lab. In the summer of 2023, he was a postdoc at Jura\u00a0bio. He completed my PhD in the Harvard Systems\u00a0Biology\u00a0program supervised by Debora Marks in 2023. He graduated with a BS in Biochemistry and Mathematics from the University of Toronto in 2019.<\/div>\n

Zoom link:<\/strong> https:\/\/wse.zoom.us\/j\/92755277282?pwd=iULpLaFnWAcWl6tQYUbeyZaN3zwBzn.1<\/p>\n","protected":false},"excerpt":{"rendered":"

Location: Shaffer 3 When: January 22nd at 1:30 p.m. Title: Machine Learning for Nature’s Overlooked Experiments Abstract: Large-scale efforts have amassed vast biological sequence data, enabling machine learning models to…<\/p>\n","protected":false},"author":69,"featured_media":0,"template":"","meta":{"_acf_changed":false,"_relevanssi_hide_post":"","_relevanssi_hide_content":"","_relevanssi_pin_for_all":"","_relevanssi_pin_keywords":"","_relevanssi_unpin_keywords":"","_relevanssi_related_keywords":"","_relevanssi_related_include_ids":"","_relevanssi_related_exclude_ids":"","_relevanssi_related_no_append":"","_relevanssi_related_not_related":"","_relevanssi_related_posts":"","_relevanssi_noindex_reason":"","_tribe_events_status":"","_tribe_events_status_reason":"","footnotes":""},"tags":[],"tribe_events_cat":[260],"class_list":["post-55401","tribe_events","type-tribe_events","status-publish","hentry","tribe_events_cat-seminars-and-endowed-lectures","cat_seminars-and-endowed-lectures"],"acf":[],"yoast_head":"\nAMS Special Seminar Series | Alan Amin | Department of Applied Mathematics and Statistics<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/engineering.jhu.edu\/ams\/event\/ams-special-seminar-series-alan-amin\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"AMS Special Seminar Series | Alan Amin | Department of Applied Mathematics and Statistics\" \/>\n<meta property=\"og:description\" content=\"Location: Shaffer 3 When: January 22nd at 1:30 p.m. Title: Machine Learning for Nature’s Overlooked Experiments Abstract: Large-scale efforts have amassed vast biological sequence data, enabling machine learning models to…\" \/>\n<meta property=\"og:url\" content=\"https:\/\/engineering.jhu.edu\/ams\/event\/ams-special-seminar-series-alan-amin\/\" \/>\n<meta property=\"og:site_name\" content=\"Department of Applied Mathematics and Statistics\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"1 minute\" \/>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"AMS Special Seminar Series | Alan Amin | Department of Applied Mathematics and Statistics","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/engineering.jhu.edu\/ams\/event\/ams-special-seminar-series-alan-amin\/","og_locale":"en_US","og_type":"article","og_title":"AMS Special Seminar Series | Alan Amin | Department of Applied Mathematics and Statistics","og_description":"Location: Shaffer 3 When: January 22nd at 1:30 p.m. Title: Machine Learning for Nature’s Overlooked Experiments Abstract: Large-scale efforts have amassed vast biological sequence data, enabling machine learning models to…","og_url":"https:\/\/engineering.jhu.edu\/ams\/event\/ams-special-seminar-series-alan-amin\/","og_site_name":"Department of Applied Mathematics and Statistics","twitter_card":"summary_large_image","twitter_misc":{"Est. reading time":"1 minute"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/engineering.jhu.edu\/ams\/event\/ams-special-seminar-series-alan-amin\/","url":"https:\/\/engineering.jhu.edu\/ams\/event\/ams-special-seminar-series-alan-amin\/","name":"AMS Special Seminar Series | Alan Amin | Department of Applied Mathematics and Statistics","isPartOf":{"@id":"https:\/\/engineering.jhu.edu\/ams\/#website"},"datePublished":"2026-01-14T15:00:00+00:00","breadcrumb":{"@id":"https:\/\/engineering.jhu.edu\/ams\/event\/ams-special-seminar-series-alan-amin\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/engineering.jhu.edu\/ams\/event\/ams-special-seminar-series-alan-amin\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/engineering.jhu.edu\/ams\/event\/ams-special-seminar-series-alan-amin\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/engineering.jhu.edu\/ams\/"},{"@type":"ListItem","position":2,"name":"Events","item":"https:\/\/engineering.jhu.edu\/ams\/events\/"},{"@type":"ListItem","position":3,"name":"AMS Special Seminar Series | Alan Amin"}]},{"@type":"WebSite","@id":"https:\/\/engineering.jhu.edu\/ams\/#website","url":"https:\/\/engineering.jhu.edu\/ams\/","name":"Hopkins Applied Math & Statistics","description":"Department of Applied Mathematics and Statistics","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/engineering.jhu.edu\/ams\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"}]}},"distributor_meta":false,"distributor_terms":false,"distributor_media":false,"distributor_original_site_name":"Department of Applied Mathematics and Statistics","distributor_original_site_url":"https:\/\/engineering.jhu.edu\/ams","push-errors":false,"_links":{"self":[{"href":"https:\/\/engineering.jhu.edu\/ams\/wp-json\/wp\/v2\/tribe_events\/55401","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/engineering.jhu.edu\/ams\/wp-json\/wp\/v2\/tribe_events"}],"about":[{"href":"https:\/\/engineering.jhu.edu\/ams\/wp-json\/wp\/v2\/types\/tribe_events"}],"author":[{"embeddable":true,"href":"https:\/\/engineering.jhu.edu\/ams\/wp-json\/wp\/v2\/users\/69"}],"version-history":[{"count":1,"href":"https:\/\/engineering.jhu.edu\/ams\/wp-json\/wp\/v2\/tribe_events\/55401\/revisions"}],"predecessor-version":[{"id":55410,"href":"https:\/\/engineering.jhu.edu\/ams\/wp-json\/wp\/v2\/tribe_events\/55401\/revisions\/55410"}],"wp:attachment":[{"href":"https:\/\/engineering.jhu.edu\/ams\/wp-json\/wp\/v2\/media?parent=55401"}],"wp:term":[{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/engineering.jhu.edu\/ams\/wp-json\/wp\/v2\/tags?post=55401"},{"taxonomy":"tribe_events_cat","embeddable":true,"href":"https:\/\/engineering.jhu.edu\/ams\/wp-json\/wp\/v2\/tribe_events_cat?post=55401"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}