News: Research Highlight

Andrew Wong, left, a materials science and engineering doctoral student, developed the metastasis research device with his faculty adviser, Peter Searson. IMAGE: WILL KIRK / HOMEWOODPHOTO.JHU.EDU

Viewing Cancer on the Move

October 31, 2014

Johns Hopkins engineers have invented a lab device to give cancer researchers an unprecedented microscopic look at metastasis, the complex way that tumor cells spread through the body, causing more than 90 percent of cancer-related deaths

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Configurations of five different (A) Cu-centered and (B) Zr-centered polyhedra, in which the center atoms are the top five atoms with the highest participation fractions for each constituent species. These are representatives of GUMs in this MG. Orange spheres are for Cu atoms and silver ones for Zr atoms.

Soft Spots and Their Structural Signature in a Metallic Glass

September 26, 2014

Jun Ding, a PhD student working with Prof. Evan Ma, has demonstrated a structure-property correlation in metallic amorphous solids. This was achieved in collaboration with Prof. Michael Falk’s group in our department. Their findings were recently published in the Proceedings for the National Academy of Sciences (PNAS).

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SKPM scanning schematic

How Static Charge Affects Organic Transistor Switching Voltages

June 9, 2014

A sideways transistor geometry correlated static charge quantitatively to changes in threshold voltage (VT) without disturbing transistor materials or interfaces, and also showed striking differences among different polymer gate materials. This will indicate more effective gate insulator choices for printed transistors with stabilized, defined VT, and inspire new material structures for other applications.

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The FRET Signatures of Noninteracting Proteins in Membranes

March 18, 2014

Förster resonance energy transfer (FRET) experiments are often used to study interactions between integral membrane proteins in cellular membranes. However, in addition to the FRET of sequence-specific interactions, these experiments invariably record a contribution due to proximity FRET, which occurs when a donor and an acceptor approach each other by chance within distances of ∼100 Å.

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toroidal structures

Toroidal Structures from Brush Amphiphiles

December 5, 2013

The self-assembly of amphiphilic block copolymers has been widely studied as an approach for engineering nano-objects. A variety of different features, including spherical micelles, cylindrical or worm-like micelles, toroids, and vesicles result from the self assembly of linear amphiphilic block copolymers by manipulating the ratio of dissimilar blocks, solvent quality, and coronal interactions.

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