Johns Hopkins engineers have invented a lab device to give cancer researchers an unprecedented microscopic look at metastasis, the complex way that tumor cells spread through the body, causing more than 90 percent of cancer-related deaths
Jun Ding, a PhD student working with Prof. Evan Ma, has demonstrated a structure-property correlation in metallic amorphous solids. This was achieved in collaboration with Prof. Michael Falk’s group in our department. Their findings were recently published in the Proceedings for the National Academy of Sciences (PNAS).
A sideways transistor geometry correlated static charge quantitatively to changes in threshold voltage (VT) without disturbing transistor materials or interfaces, and also showed striking differences among different polymer gate materials. This will indicate more effective gate insulator choices for printed transistors with stabilized, defined VT, and inspire new material structures for other applications.
Förster resonance energy transfer (FRET) experiments are often used to study interactions between integral membrane proteins in cellular membranes. However, in addition to the FRET of sequence-specific interactions, these experiments invariably record a contribution due to proximity FRET, which occurs when a donor and an acceptor approach each other by chance within distances of ∼100 Å.
The construction of hybrid systems −those involving multiple components exhibiting distinct physicochemical characteristics− through non-directional interactions results from a balance between self-organization and integrative co-assembly.
The self-assembly of amphiphilic block copolymers has been widely studied as an approach for engineering nano-objects. A variety of different features, including spherical micelles, cylindrical or worm-like micelles, toroids, and vesicles result from the self assembly of linear amphiphilic block copolymers by manipulating the ratio of dissimilar blocks, solvent quality, and coronal interactions.
Aliphatic polycarbonates and polyesters are two important classes of biocompatible and biodegradable materials widely used for drug delivery and tissue engineering applications.
Johns Hopkins engineers and cardiology experts have teamed up to develop a fingernail-sized biosensor that could alert doctors when serious brain injury occurs during heart surgery.