Wang, Jeff

Professor
Department Of Mechanical Engineering

Latrobe Hall 108
3400 N Charles St
(410) 516-7086
thwang@jhu.edu

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About

Education
  • Ph.D. 2002, University of California, Los Angeles
  • M.S. 1994, National Taiwan University
  • B.S. 1992, National Taiwan University
Experience
  • 1998-2002: Research Assistant, University of California, Los Angeles
  • 1996-1998: Manufacturing Engineer, Taiwan Semiconductor Manufacturing Company (TSMC)
  • 1994-1996: Second Lieutenant, Marine Army, Taiwan, R.O.C.
Research Areas
  • BioMEMS and Microfluidics
  • Nano/Micro Scale Fabrication
  • Single Molecule Manipulation and Detection
  • Genetic and epigenetic Biomarker for cancer
Awards
  • 2012:  Best Paper Award - The 6th IEEE International Conference on Nano/Molecular Medicine and Engineering (IEEE NANOMED 2012)
  • 2012:  JALA & JBS Art of Science Award awarded to Wang's students Y Zhang and C Beh
  • 2012:  NIST/ Lab on a Chip Art in Science Award - micro-TAS 2012 - awarded to Wang's graduate student Yi Zhang
  • 2012:  Siebel Scholar Award awarded to Wang's student Yi Zhang
  • 2011:  Best Paper Award - The 6th Annual IEEE International Conference on Nano/Micro Engineered and Molecular Systems (IEEE NEMS 2011)
  • 2011:  Best Poster Award - 5th Annual INBT NanoBio Symposium
  • 2011:  JALA Ten Award - Journal of Laboratory Automation - Society for Laboratory Automation and Screening
  • 2011:  NIST/ Lab on a Chip Art in Science Award - micro-TAS 2011 - awarded to Wang's graduate student DJ Shin &Yi Zhang
  • 2010:  American Association for Cancer Research (AACR) Scholar-in-Training Award awarded to Wang's graduate student Yi Zhang
  • 2010:  Best Poster Award - 4th Johns Hopkins NanoBio Symposium
  • 2010:  Siebel Scholar Award awarded to Wang's graduate student Kelvin Liu
  • 2009:  Best Poster Award - 3rd Johns Hopkins NanoBio Symposium
  • 2009:  Johns Hopkins University Provost's Undergraduate Research Award (PURA) awarded to Wang's undergraduate student Brian Keeley
  • 2009:  Siebel Scholar Award awarded to Wang's graduate student Vas Bailey
  • 2007:  Co-author and Faculty Advisor to Hunter Chen - winner of Excellence in Research Award - American Society of Gene Therapy
  • 2007:  CRS Jorge Heller Award - Journal of Controlled Release Oustanding Paper Award
  • 2006:  CAREER Award - National Science Foundatiom
  • 2004:  Johns Hopkins University Provost's Undergraduate Research Award (PURA) awarded to Wang's undergraduate student Marcos Kuroki
  • 2003:  Johns Hopkins University Provost's Undergraduate Research Award (PURA) awarded to Wang's undergraduate student Eric Simone
  • 2002:  Best Paper/Travel Award - the First World Congress for Chinese Biomedical Engineers - held in Taipei - Taiwan
Presentations
  • K.J. Liu, T.D. Rane, Y. Zhang, C. Beh, D.J. Shin, T.H. Wang, “An Integrated Platform for Single Molecule Free Solution Hydrodynamic Separation Using Yoctomoles of DNA and Picoliter Samples”, ASME 10th International Conference on Nanochannels, Microchannels and Minichannels (ICNMM), (Presented by Wang's postdoc K.J. Liu), July 10, 2013
  • C.H. Chiou, D.J. Shin, S. Hosmane, Y Zhang and T.H. Wang, “Electromagnet-Actuated Droplet Platform for Sample-to-Answer Genetic Detection”, 26th IEEE International Conference on Micro Electro Mechanical Systems (IEEE MEMS 2013) (Presented by Wang's postdoc C.H. Chiou), January 22, 2013
  • H. C. Zec, T.D. Rane, W.C. Chu, V. Wang and T.H. Wang, " A Microfluidic Droplet Platform for Multiplexed Single Nucleotide Polymorphism Analysis of an Array Plant Genomic DNA Samples", Proc. 26th IEEE International Conference on Micro Electro Mechanical Systems (IEEE MEMS 2013) (Presented by Wang's student H.C. Zec), January 21, 2013
  • The KUST International Conference on Biomedical Engineering, HKUST, Hong Kong (Invited), January 11, 2013
  • C. W. Beh, C. Weiss, H.Q. Mao, D. L. Kraitchman, and T.H. Wang, “High-Throughput Microfluidic Preparation of Imaging-Visible Embolic Beads”, EMBS Micro and Nanotechnology in Medicine Conference (Poster presentation), December 6, 2012
  • Nanomedicine Lecture Series, Northeastern University, Boston, MA (Invited), November 20, 2012
  • NCI Alliance for Nanotechnology in Cancer Meeting, Houston, TX (Invited), November 15, 2012
  • Y. Zhang, Y. Zhang, B. Keeley, A. Stark and T.H. Wang, “Fabricating and Applying Hierarchical Silica Nanomembrane with for Solid Phase DNA Extraction” The 6th IEEE International Conference on Nano/Molecular Medicine and Engineering (IEEE NANOMED) (Presented by Wang's student Y Zhang), November 6, 2012
  • The 6th IEEE International Conference on Nano/Molecular Medicine and Engineering (IEEE-NANOMED 2012), Bangkok (Invited), November 4, 2012
  • Y. Zhang and T.H. Wang, “Droplet Immobilization, Splitting, Metering and Aliquoting with Surface Energy Traps Created Using SU8 Shadow Mask” International Conference on Miniaturized Chemical and Biochemical Analysis Systems (micro-TAS) (Presented by Wang's student Y. Zhang), October 30, 2012
  • Y. Zhang and T.H. Wang, “Surface Energy Trap Assisted Rapid Serial Dilution on Droplet Platform for Bacteria Antibiotics Susceptibility Test” International Conference on Miniaturized Chemical and Biochemical Analysis Systems (micro-TAS) (Poster presentation), October 30, 2012
  • D.D. Nalayanda, W.B. Fulton, T.H. Wang, F. Abdullah, "A Multifluidic Platform for Studying Ventilator-Induced Injury of the Epithelia Barrier", Biomedical Engineering Society Annual Meeting (BMES) (Poster presentation), September 26, 2012
  • D. Kraitchman, C.R. Weiss, C.W. Beh, C. Hu, P. Dicamillo, Y. Fu, J.A. Cook, K.L. Gabrielson, T.H. Wang, H.Q. Mao, "In vivo Biocompatibility and Efficacy of an X-ray-visible, Uniform, Alginate Microshpere for Embolic Therapy", World Molecular Imaging Congress (WMIC), Dublin, Ireland, September, 2012 (Poster presentation), September 6, 2012
  • B. Keely, Y. Song, L. Zhang, M. Chen and T.H. Wang, “Single Quantum Dot Fluorescence Enhancement by Tunable Nanoporous Gold”, IEEE 12th International Conference on Nanotechnology (IEEE NANO 2012)(Presented by Wang's student B. Keely), August 23, 2012
  • B. Keeley, Yi Zhang, Ye Zhang, A. Stark, T.H. Wang, “Quantum Dot FRET Linker Probes for Highly Sensitive DNA Methylation Detection”, 12th International Conference on Nanotechnology (IEEE NANO) (Presented by Wang's student B. Keeley), August 21, 2012
  • T.H. Wang and Y. Zhang , “Quantum Dot Electrophoretic Mobility Shift Assay and Its Application to the Measurement of Exonuclease Activity”, 12th International Conference on Nanotechnology (IEEE NANO), August 21, 2012
  • T.D. Rane and H. Zec, W.C. Chu and T.H. Wang, “Multiplexed Screening of a Large Library of Biological Samples through on-Demand Droplet Generation and Fusion”, ASME 2012 10th International Conference on Nanochannels, Microchannels and Minichannels (ICNMM 2012) (Presented by Wang's student T.D. Rane), July 10, 2012
  • Seminar at the Department of Mechanical and Electro-Mechanical Engineering, National Sun Yat-Sen University, Kaohsiung, Taiwan (Invited), June 21, 2012
  • The 4th International Symposium on Microchemistry and Microsystems (ISMM 2012), Hsinchu, Taiwan (Invited), June 12, 2012
  • Y. Zhang and T.H. Wang, "Surface Energy Trap Enabled Complex Droplet Manipulation Platform for Point-of-care Diagnostics" ACS Colloids and Surfaces Symposium (Presented by Wang's student Y. Zhang), June 12, 2012
  • Y. Zhang and T.H. Wang, "High Resolution Genetic and Epigenetic Analysis by Mapping DNA Quantity into Electrophoretic Mobility through Quantum Dot Nanotether", ACS Colloids and Surfaces Symposium (Presented by Wang's student Y. Zhang), June 11, 2012
  • Naon-Bio Symposium “Cancer The Big Picture”, Johns Hopkins University, Baltimore, MD (Invited), May 4, 2012
  • NIH/NIBIB Nano-SIG Seminar Series, National Institutes of Health, Bethesda, MD (Invited), April 17, 2012
  • C. Weiss, P.A. DiCamillo, C.W. Beh, T.H. Wang, H.Q. Mao, D. Kraitchman, "Gastric artery embolization with X-ray-visible embolic beads and c-arm cone beam CT for increased accuracy," Annual Scientific Meeting of Society of Interventional Radiology (SIR) (Poster presentation), March 25, 2012
  • H. Zec, Y. Zhang and T.H. Wang, “Flip-Drop: Droplet Array Created by Surface Energy Trap for Combinatorial Screening,” 26th IEEE International Conference on Micro Electro Mechanical Systems (IEEE MEMS 2013) (poster presentation), January 23, 2012
  • H. Zec and Y. Zhang and T.H. Wang “ All-in-One Droplet Platform for Multiplexed Genetic Detection in Blood” 26th IEEE International Conference on Micro Electro Mechanical Systems (IEEE MEMS 2013)(poster presentation), January 22, 2012
  • MF3 Industrial Advisory Board (IAB) Meeting / DARPA NEMS/MEMS S&T Fundamentals PI Meeting, Arlington, VA, December 8, 2011
  • NCI Innovative Molecular Analysis Technologies Program,12th Principal Investigators Meeting, Bethesda, MD, November 14, 2011
  • The 5th IEEE International Conference on Nano/Molecular Medicine and Engineering (IEEE-NANOMED 2011), Jeju Island, Korea, November 9, 2011
  • DuPont Pioneer Hi-Bred Seminar Series, Johnston, Iowa, October 31, 2011
  • Mechanical Engineering Department, Johns Hopkins University, Baltimore, MD, October 20, 2011
  • The 15th International Conference on Miniaturized Chemical and Biochemical Analysis Systems (micro-TAS 2010), Seattle, Washington, October 4, 2011
  • NCI Alliance for Nanotechnology in Cancer Annual Principal Investigators’ Meeting, Boston, MA, September 20, 2011
  • The 33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC ’11), Boston, MA (Presented by postdoc K. Liu), September 3, 2011
  • Cancer Detection and Diagnostics Technologies for Global Health, Rockville, Maryland, August 22, 2011
  • The First Annual EITC Young Investigator Conference, Cambridge, MA, August 18, 2011
  • The 16th International Conference on Solid-State Sensors, Actuators and Microsystems (Transducers 2011), Beijing, China (Presented by student Y. Zhang), June 6, 2011
  • SPIE Defense, Security and Sensing Conference, Orlando, FL, April 27, 2011
  • Monsanto Chemistry Seminar Series, St. Louis, MO, April 19, 2011
  • SLAS Lab Automation Conference and Exhibition (Lab Automation 2011), Palm Springs, CA, February 1, 2011
  • The Lab Automation Conference and Exhibition (Lab Automation 2011), February 1, 2011
  • The 6th Annual IEEE International Conference on Nano/Micro Engineered and Molecular Systems (IEEE-NEMS), Kaohsiung, Taiwan, January 21, 2011
  • MF3 Industrial Advisory Board (IAB) Meeting  / DARPA NEMS/MEMS S&T Fundamentals PI Meeting, December 14, 2010
  • 2010 IEEE International Conference on Nano/Molecular Medicine and Engineering (IEEE-NANOMED 2010), Hong Kong, December 6, 2010
  • NIH/NIAID Middle Atlantic Regional Center of Excellence (MARCE) PI meeting, November 15, 2010
  • 2010 Biomaterials Day Symposium, Baltimore, MD, October 29, 2010
  • 14th International Conference on Miniaturized Chemical and Biochemical Analysis Systems (micro-TAS 2010), Groningen, Netherlands(Presented by student C. Beh & Y. Zhang), October 3, 2010
  • 2nd Johns Hopkins Ovarian Cancer Symposium: Early Carcinogenesis, Cancer Genomics & Biology, Baltimore, MD, September 30, 2010
  • 2010 Gordon Conference on Bioanalytical Sensors, New London, NH, June 22, 2010
  • NIH/NIAID Middle Atlantic Regional Center of Excellence (MARCE) PI meeting, June 2, 2010
  • Fischell Department of Bioengineering, University of Maryland, College Park,  MD, April 23, 2010
  • 6th National RCE Meeting, Las Vegas, Nevada, April 12, 2010
  • 23rd IEEE International Conference on Micro Electro Mechanical Systems (IEEE MEMS2010), Hong Kong (Presented by student Y. Zhang), January 24, 2010
  • Integrating Micro- and Nano-Technologies for Analysis of Biomolecules Cell Biophysics Symposium, School of Medicine. Baltimore, Maryland. 2008-11-24. (Invited), November 24, 2008
  • Nanobiosensing Method for Molecular Analysis of Cancer NIH NCI Innovative Molecular Analysis Technologies (IMAT) Program PI meeting. Boston. Massachusetts. 2008-10-28., October 28, 2008
  • Microfluidic, Free-Standing Corneal Epithelium through Enzymatic Etching within Hybrid PDMS-Collagen Devices Biomedical Engineering Society Annual Meeting. St. Louis, Missouri. 2008-10-03., October 3, 2008
  • Micro/Nanotechnology for Ultrasensitive and High-throughput Biomolecular Analysis Pathology Grand Rounds, Johns Hopkins School of Medicine. Baltimore. Maryland. 2008-09-18. (Invited), September 18, 2008
  • Microfluidic Single-Molecule Platform for Ultrasensitive Detection Symposium Toward a Strategic Vision for Basic Sciences for Chemical and Biological Defense. Atlanta, Georgia. 2008-08-07. (Invited), August 7, 2008
  • E. Coli Detection in Picoliter Droplets using Confocal Fluorescence Detection MF3 Industrial Advisory Board (IAB) Meeting. Irvine, California. 2008-08-06., August 6, 2008
  • Quantum Dots For Molecular Analysis of Cancers NanoBio Symposium 2008, Institute for NanoBiotechnology & The Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins School of Medicine. Baltimore, Maryland. 2008-05-01. (Invited), May 1, 2008
  • Towards Single-Molecule Diagnostics Using Microfluidic Manipulation and Quantum Dot Nanosensors Departmental Seminar, Department of Aerospace and Mechanical Engineering, University of Arizona. Tucson, Arizona. 2008-04-10. (Invited), April 10, 2008
  • Ultratrace Detection of Explosives Enabled by an Integrated Microfluidic Nanosensing System NSF/DHS S&T Explosives and Related Threats: Frontiers in Prediction and Detection (EXP) Grantees Conference. Arlington, Virginia. 2008-01-17., January 17, 2008
  • Quantitative Kinetic Analysis of DNA Nanocomplex Self-Assembly with Quantum Dots FRET in a Microfluidic Device 21st IEEE International Conference on Micro Electro Mechanical Systems. . 2008-01-14., January 14, 2008
  • E. Coli Detection in Picoliter Droplets Using Confocal Fluorescence Detection MF3 Industrial Advisory Board (IAB) Meeting / DARPA NEMS/MEMS S&T Fundamentals PI Meeting. Napa Valley, California. 2008-01-13., January 13, 2008
  • Quantitative Confocal Spectroscopy – Rectifying the Limitations of Single Molecule Detection The 3rd Annual IEEE International Conference on Nano/Micro Engineered and Molecular Systems (IEEE-NEMS). Sanya, Hainan, China. 2008-01-00. (Invited), December 31, 2007
  • Towards Single-Molecule Diagnostics Using Microfluidic Manipulation and Quantum Dot Nanosensors Seminar: Department of Mechanical Engineering and Mechanics, Drexel University. Philadelphia, Pennsylvania. 2007-11-00. (Invited), October 31, 2007
  • Integrating Micro- and Nano-Technologies for Analysis of Biomolecules Division Seminar: Department of Oncology, Johns Hopkins Medical Institute. Baltimore, Maryland. 2007-09-00. (Invited), August 31, 2007
  • Quantum Dots-FRET-Based Nanosensors for Point Mutation Detection HUGO IX International Symposium on Mutation in The Genome (2007 Mutation Detection). Xiamen, China. 2007-09-00. (Invited), August 31, 2007
  • Towards Single-Molecule Diagnostics Using Microfluidic Manipulation and Quantum Dot Nanosensors The Symposium: Nano Meets Micro, Center of Advanced Learning in Information Technologies (CALIT), IMEC. Leuven, Belgium. 2007-09-00. (Invited), August 31, 2007
  • QD-FRET Detection of E-coli in Microfluidic Droplets MF3 Industrial Advisory Board (IAB) Meeting / DARPA NEMS/MEMS S&T Fundamentals PI Meeting. San Francisco, California. 2007-06-00. (Invited), May 31, 2007
  • Towards Single-Molecule Diagnostics Using Microfluidic Manipulation and Quantum Dot Nanosensors Bureau of Forensic Services, Department of Justice, Sate of California. Richmond, California. 2007-06-00. (Invited), May 31, 2007
  • Towards Single-Molecule Diagnostics Using Microfluidic Manipulation and Quantum Dot Nanosensors Fifth International Conference on Nanochannels, Microchannels and Minichannels (ASME ICNMM 2007). Puebla, Mexico . 2007-06-00. (Invited), May 31, 2007
  • Towards Single-Molecule Diagnostics Using Microfluidic Manipulation and Quantum Dot Nanosensors Department of Electrical and Computer Engineering, University of Maryland, College Park. Maryland. 2007-03-00. (Invited), February 28, 2007
  • Towards Single-Molecule Diagnostics Using Microfluidic Manipulation and Quantum Dot Nanosensors Divisional Research Seminars in the Division of Gynecological Pathology, Johns Hopkins Medical Institute. Baltimore, Maryland. 2006-11-14. (Invited), November 14, 2006
  • Pushing The Sensitivity of Nanoscale Biosensing Systems to The Fundamental Limit PI Meeting, DARPA N/MEMS Science and Technology Fundamentals / Micro/Nano Fluidics Fundamentals Focus (MF3) Center. Minneapolis, Minnesota. 2006-10-26. (Invited), October 26, 2006
  • Integrating single-molecule detection, quantum dot nanosensors, and microfluidic manipulations for analysis of low-abundance biomolecules The 2nd American Academy of Nanomedicine Annual Meeting. Washington DC. 2006-09-09. (Invited), September 9, 2006
  • Single Molecule Quantitative Detection and Analysis of Low-Abundance Biomolecules The Symposium: Mining the Biology-Physics Interface, Biology Department, Johns Hopkins University. Baltimore, Maryland. 2006-01-25. (Invited), January 25, 2006
  • Towards Single-Molecule Diagnostics Using Microfluidic Manipulation and Quantum Dot Nanosensors Biomedical Engineering Department, University of California, Irvine. Irvine, California. 2006-01-12. (Invited), January 12, 2006
  • Integrative Innovations in Nanotechnologies, Single-Molecule Detection and Microlfuidics for Sensing & Quantification of Biomolecules . Howard Hughes Medical Institute, Johns Hopkins Medical School. 2005-11-23., November 23, 2005
  • Integrating Microfluidic Manipulations and Single-Molecule Detection for Quantitative Analysis of Biomolecules on a Chip 6th Annual CAMD/CBM2 Summer Workshop. Barton Rouge, LA. 2005-07-25. (Invited), July 25, 2005
  • Point Mutation Detection with Quantum Dot Nanosensor International Conference on Bio-Nano-Information Fusion. Marina DelRay, California. 2005-07-21., July 21, 2005
  • Quantitative Detection of Biomolecules with Microfluidic Manipulations and Single-molecule Detection The Chinese Biopharmaceutical Association (CBA) Annual Conference. Rockville, Maryland. 2005-06-19. (Invited), June 19, 2005
  • Integrative Innovations in Nanotechnologies, Single-Molecule Detection and Microlfuidics for Sensing & Quantification of Biomolecules . Pathology Department, Johns Hopkins Medical School . 2005-01-14., January 14, 2005
  • Micro/Nano Technologies for Single-Molecule Detection NioMEMS and Nanotech World 2004. Washington, D.C.. 2004-08-18. (Invited), August 18, 2004
  • Ultrasensitive Quantitative Analysis of Biomolecules Using Single-molecule Detection and Micro Fluidic Devices Invited talk at Peking University. Beijing, China . 2004-05-24. (Invited), May 24, 2004
  • Ultrasensitive Quantitative Analysis of Biomolecules Using SIngle-molecule Detection and Micro FLuidic Devices Invited Talk at Shanghai Jaio Tong University. Shanghai, China. 2004-05-21. (Invited), May 21, 2004
  • Ultrasensitive Genomic Analysis Using Single-molecule Detection, Micro Fluidic Chips, and Nanoparticle Molecular Probes The First U.S. -China Nanotechnology Forum. Beijing, China. 2004-05-17. (Invited), May 17, 2004
  • Ultrasensitive Bio-Detection with Quantum Dot-based Nano Biosensors Invited Talk at Sensors and Electron Devices Directorate, Army Research Laboratory. Army Research Laboratory . 2004-02-24. (Invited), February 24, 2004
  • Specific Single-Biomolecule Detection Mechanical Engineering Departmental Seminar, Johns Hopkins University. Baltimore, MD. 2003-10-23., October 23, 2003
  • Nano/Micro Technologies for Single Molecule Manipulation and Detection 2003 IEEE International Conference on Robotics and Automation . Taipei, Taiwan. 2003-09-17. (Invited), September 17, 2003
  • Specific Single-Biomolecule Detection Using Fluorescence Correlation Spectroscopy and Quantum-dot Probes Invited Talk in the Biomedical Engineering Department at University of Southern California . Los Angeles, California. 2003-09-07., September 7, 2003
  • Specific Single-Biomolecule Detection Using Fluorescence Correlation Spectroscopy and Quantum-dot Probes Invited Talk at the Center for Cell Mimetic Space Exploration (CMISE) at University of California, Los Angeles. Los Angeles, California. 2003-09-05., September 5, 2003
  • BioMEMS for Single Molecule Manipulation and Detection 2003 BioMEMS Conference. San Jose, Claifornia. 2003-06-17. (Invited), June 17, 2003
  • BioMEMS Devices for Control and Manipulation of Single Molecules CISSTS ERC (Engineering Research Center for Computer-Integrated Surgical Systems and Technology ) Seminar . . 2003-04-09. (Invited), April 9, 2003
  • Nano/Micro Technology for Detecting a Single DNA Molecule 2002 World Congress for Chinese Biomedical Engineer (WCCBME2002). Taipei, Taiwan. 2002-12-11., December 11, 2002
  • High Throughput, Quantitative DNA Methylation Screening Using a Quantum Dot Based Nanotechnology Assay 2. AACR Molecular Diagnostics in Cancer Therapeutic Development conference: Fulfilling the Promise of Personalized Medicine,. Philadelphia, Pennsylvania, . 0000-00-00., November 30, 1999
  • Single-Molecule Quantitative Detection and Analysis of Low-Abundance Biomolecules The Symposium: Mining the Biology-Physics Interface, Biology Department, Johns Hopkins University. Baltimore, Maryland. 0000-00-00., November 30, 1999

Publications

Journal Articles
  • Wang, T.H. (2013). Discerning single molecule interactions of DNA and quantum dots. Biotechnology Journal. 8(1). 15-16.
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    View record in Web of Science SM
  • Zhang, Y., Wang, T.H. (2012). Quantum dot enabled molecular sensing and diagnostics. Theranostics. 2(7). 631-54.
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  • Zhang, Y., Liu, K.J., Wang, T.L., Shih, I.M, Wang, T.H. (2012). Mapping DNA Quantity into Electrophoretic Mobility through Quantum Dot Nanotethers for High-Resolution Genetic and Epigenetic Analysis.. ACS Nano. 6(1). 858-64.
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  • Zec, H., Rane, T.D., Wang, T.H. (2012). Microfluidic platform for on-demand generation of spatially indexed combinatorial droplets. Lab on a Chip. 12(17). 3055-3062.
    View record in Web of Science SM
  • Beh, C.W., Zhou, W.Z., Wang, T.H. (2012). PDMS-glass bonding using grafted polymeric adhesive - alternative process flow for compatibility with patterned biological molecules. Lab on a Chip. 12(20). 4120-4127.
    View record in Web of Science SM
  • Rane, T.D., Zec, H.C., Puleo, C., Lee, A.P., Wang, T.H. (2012). Droplet microfluidics for amplification-free genetic detection of single cells. Lab on a Chip. 12(18). 3341-7.
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  • Song, Y., Zhang, Y., Wang, T.H. (2012). Single Quantum Dot Analysis Enables Multiplexed Point Mutation Detection by Gap Ligase Chain Reaction. Small.
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  • Rane, T.D., Zec, H.C., Wang, T.H. (2012). A serial sample loading system: interfacing multiwell plates with microfluidic devices. J Lab Autom. 17(5). 370-7.
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  • Zhang, Y., Park, S., Liu, K., Tsuan, J., Yang, S., Wang, T. (2011). A surface topography assisted droplet manipulation platform for biomarker detection and pathogen identification. Lab on a Chip. 11(3). 398-406.
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  • Zhang, Y., Wang, T.H. (2011). Micro magnetic gyromixer for speeding up reactions in droplets. Microfluidics and Nanofluidics. 1-8.
  • Zhang, Y., Wang, T.H. (2011). Quantum dots-enabled high-resolution analysis of gene copy number variation: Electrophoretic migration and band broadening of QD-DNA nanocomplex. IEEE Nanotechnology Magazine. 5(2). 23-27.
  • Liu, K.J., Rane, T.D., Zhang, Y., Wang, T.H. (2011). Single-molecule analysis enables free solution hydrodynamic separation using yoctomole levels of DNA. Journal of the American Chemical Society. 133(18). 6898-6901.
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  • Park, S., Zhang, Y., Wang, T.H., Yang, S. (2011). Continuous dielectrophoretic bacterial separation and concentration from physiological media of high conductivity. Lab on a Chip - Miniaturisation for Chemistry and Biology. 11(17). 2893-2900.
  • Park, S., Zhang, Y., Lin, S., Wang, T.H., Yang, S. (2011). Advances in microfluidic PCR for point-of-care infectious disease diagnostics. Biotechnology Advances. 29(6). 830-839.
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  • Zhang, Y., Park, S., Yang, S., Wang, T. (2010). An all-in-one microfluidic device for parallel DNA extraction and gene analysis. Biomedical Microdevices. 12(6). 1043-1049.
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  • Zhang, Y., Park, S., Yang, S., Wang, T.H. (2010). An all-in-one microfluidic device for parallel DNA extraction and gene analysis.. Biomed Microdevices. 12(6). 1043-9.
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  • Wang, T., Wong, P.K. (2010). Transforming Microfluidics into Laboratory Automation. Jala. 15(3).
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  • Liu, K.J., Brock, M.V., Shih, I.M., Wang, T.H. (2010). Decoding circulating nucleic acids in human serum using microfluidic single molecule spectroscopy. Journal of the American Chemical Society. 132(16). 5793-5798.
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  • Nalayanda, D.D., Wang, Q., Fulton, W.B., Wang, T.H., Abdullah, F. (2010). Engineering an artificial alveolar-capillary membrane: a novel continuously perfused model within microchannels. Journal of Pediatric Surgery. 45(1). 45-51.
    DOI » View record in Web of Science SM
  • Wang, T.H., Wong, P.K. (2010). Transforming Microfluidics into Laboratory Automation. JALA - Journal of the Association for Laboratory Automation. 15(3).
  • Rane, T., Puleo, C., Liu, K., Zhang, Y., Lee, A., Wang, T. (2010). Counting single molecules in sub-nanolitre droplets. Lab on a Chip. 10(2). 161-164.
    DOI » View record in Web of Science SM
  • Bailey, V.J., Keeley, B.P., Razavi, C.R., Griffiths, E., Carraway, H.E., Wang, T. (2010). DNA methylation detection using MS-qFRET, a quantum dot-based nanoassay. Methods. 52(3). 237-241.
    DOI » View record in Web of Science SM
  • Jiang, X., Zheng, Y., Chen, H.H., Leong, K.W., Wang, T.H., Mao, H.Q. (2010). Dual-sensitive micellar nanoparticles regulate dna unpacking and enhance gene-delivery efficiency. Advanced Materials. 22(23). 2556-2560.
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  • Bailey, V.J., Zhang, Y., Keeley, B.P., Yin, C., Pelosky, K.L., Brock, M., Baylin, S.B., Herman, J.G., Wang, T.H. (2010). Single-tube analysis of DNA methylation with silica superparamagnetic beads. Clinical Chemistry. 56(6). 1022-1025.
    DOI » View record in Web of Science SM
  • Bailey, V.J., Keeley, B.P., Razavi, C.R., Griffiths, E., Carraway, H.E., Wang, T.H. (2010). DNA methylation detection using MS-qFRET, a quantum dot-based nanoassay.. Methods. 52(3). 237-41.
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  • Bailey, V.J., Keeley, B.P., Zhang, Y., Ho, Y.P., Easwaran, H., Brock, M.V., Pelosky, K.L., Carraway, H.E., Baylin, S.B., Herman, J.G., Wang, T.H. (2010). Enzymatic incorporation of multiple dyes for increased sensitivity in QD-FRET sensing for DNA methylation detection. ChemBioChem. 11(1). 71-74.
    DOI » View record in Web of Science SM
  • Zhang, Y., Bailey, V., Puleo, C., Easwaran, H., Griffiths, E., Herman, J., Baylin, S., Wang, T. (2009). DNA methylation analysis on a droplet-in-oil PCR array. Lab on a Chip. 1059-1064.
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    View record in Web of Science SM
  • Nalayanda, D., Puleo, C., Fulton, W., Sharpe, L., Wang, T., Abdullah, F. (2009). An open-access microfluidic model for lung-specific functional studies at an air-liquid interface. Biomedical Microdevices. 11(5). 1081-1089.
    DOI » View record in Web of Science SM
  • Puleo, C.M., Wang, T. (2009). Microfluidic means of achieving attomolar detection limits with molecular beacon probes. Lab on a Chip. 9(8). 1065-1072.
    DOI » View record in Web of Science SM
  • Puleo, C.M., Wang, T.H. (2009). Microfluidic means of achieving attomolar detection limits with molecular beacon probes. Lab on a Chip - Miniaturisation for Chemistry and Biology. 9(8). 1065-1072.
  • Ho, Y.P., Chen, H.H., Leong, K.W., Wang, T.H. (2009). Combining QD-FRET and microfluidics to monitor DNA nanocomplex self-assembly in real-time. Journal of visualized experiments : JoVE. (30).
  • Ho, Y.P., Chen, H.H., Leong, K.W., Wang, T.H. (2009). The convergence of quantum-dot-mediated fluorescence resonance energy transfer and microfluidics for monitoring DNA polyplex self-assembly in real time. Nanotechnology. 20(9).
    DOI » View record in Web of Science SM
  • Chen, H., Ho, Y., Jiang, X., Mao, H., Wang, T., Leong, K. (2009). Simultaneous non-invasive analysis of DNA condensation and stability by two-step QD-FRET. Nano Today. 4(2). 125-134.
    DOI » View record in Web of Science SM
  • Chen, H.H., Ho, Y.P., Jiang, X., Mao, H.Q., Wang, T.H., Leong, K.W. (2009). Erratum to Simultaneous non-invasive analysis of DNA condensation and stability by two-step QD-FRET [Nano Today 4 (2009) 125-134] (DOI:10.1016/j.nantod.2009.02.008). Nano Today. 4(3). 280.
    DOI » View record in Web of Science SM
  • Puleo, C., Ambrose, W., Takezawa, T., Elisseeff, J., Wang, T. (2009). Integration and application of vitrified collagen in multilayered microfluidic devices for corneal microtissue culture. Lab on a Chip. 9(22). 3221-3227.
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  • Bailey, V., Easwaran, H., Zhang, Y., Griffiths, E., Belinsky, S., Herman, J., Baylin, S., Carraway, H., Wang, T. (2009). MS-qFRET: A quantum dot-based method for analysis of DNA methylation. Genome Research. 19(8). 1455-1461.
    DOI » View record in Web of Science SM
  • Yeh, H.C., Puleo, C.M., Ho, Y.P., Bailey, V.J., Teck, C.L., Liu, K., Wang, T.H. (2008). Tunable blinking kinetics of Cy5 for precise DNA quantification and single-nucleotide difference detection. Biophysical Journal. 95(2). 729-737.
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  • Lim, T.C., Bailey, V.J., Ho, Y.P., Wang, T.H. (2008). Intercalating dye as an acceptor in quantum-dot-mediated FRET. Nanotechnology. 19(7).
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  • Liu, K.J., Wang, T.H. (2008). Cylindrical illumination confocal spectroscopy: Rectifying the limitations of confocal single molecule spectroscopy through one-dimensional beam shaping. Biophysical Journal. 95(6). 2964-2975.
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  • Liu, K.J., Zhang, Y., Wang, T.H. (2008). Detect the dots. IEEE Nanotechnology Magazine. 2(1). 14-18.
  • Chen, H., Ho, Y., Jiang, X., Mao, H., Wang, T., Leong, K. (2008). Quantitative comparison of intracellular unpacking kinetics of polyplexes by a model constructed from quantum Dot-FRET. Molecular Therapy. 16(2). 324-332.
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  • Puleo, C.M., Yeh, H.C., Liu, K.J., Wang, T.H. (2008). Coupling confocal fluorescence detection and recirculating microfluidic control for single particle analysis in discrete nanoliter volumes. Lab on a Chip. 8(5). 822-825.
    DOI » View record in Web of Science SM
  • Nalayanda, D.D., Puleo, C.M., Fulton, W.B., Wang, T.H., Abdullah, F. (2007). Characterization of pulmonary cell growth parameters in a continuous perfusion microfluidic environment. Experimental Lung Research. 33(6). 321-335.
    DOI » View record in Web of Science SM
  • Puleo, C.M., Yeh, H.C., Wang, T.H. (2007). Applications of MEMS technologies in tissue engineering. Tissue Engineering. 13(12). 2839-2854.
    DOI » View record in Web of Science SM
  • Chao, S.Y., Ho, Y.P., Bailey, V.J., Wang, T.H. (2007). Quantification of low concentrations of DNA using single molecule detection and velocity measurement in a microchannel. Journal of Fluorescence. 17(6). 767-774.
    DOI » View record in Web of Science SM
  • Yeh, H., Ho, Y., Shih, I., Wang, T. (2006). Homogeneous point mutation detection by quantum dot-mediated two-color fluorescence coincidence analysis. Nucleic Acids Research. 34(5).
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  • Yeh, H.C., Puleo, C.M., Lim, T.C., Ho, Y.P., Giza, P.E., Huang, R.C.C., Wang, T.H. (2006). A microfluidic-FCS platform for investigation on the dissociation of Sp1-DNA complex by doxorubicin. Nucleic Acids Research. 34(21).
    DOI » View record in Web of Science SM
  • Puleo, C.M., Liu, K., Wang, T. (2006). Pushing miRNA quantification to the limits: high-throughput miRNA gene expression analysis using single-molecule detection. Nanomedicine. 1(1). 123-127.
    DOI » View record in Web of Science SM
  • Ho, Y., Chen, H., Leong, K., Wang, T. (2006). Evaluating the intracellular stability and unpacking of DNA nanocomplexes by quantum dots-FRET. Journal of Controlled Release. 116(1). 83-89.
    DOI » View record in Web of Science SM
  • Zhang, C., Yeh, H., Kuroki, M., Wang, T. (2005). Single-quantum-dot-based DNA nanosensor. Nature Materials. 4(11). 826-831.
    DOI » View record in Web of Science SM
  • Zhang, C., Chao, S., Wang, T. (2005). Comparative quantification of nucleic acids using single-molecule detection and molecular beacons. Analyst. 130(4). 483-488.
    DOI » View record in Web of Science SM
  • Yeh, H., Chao, S., Ho, Y., Wang, T. (2005). Single-molecule detection and probe strategies for rapid and ultrasensitive genomic detection. Current Pharmaceutical Biotechnology. 6(6). 453-461.
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  • Yeh, H.C., Ho, Y.P., Wang, T.H. (2005). Quantum dot-mediated biosensing assays for specific nucleic acid detection.. Nanomedicine. 1(2). 115-21.
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  • Wang, T., Peng, Y., Zhang, C., Wong, P., Ho, C. (2005). Single-molecule tracing on a fluidic microchip for quantitative detection of low-abundance nucleic acids. Journal of the American Chemical Society. 127(15). 5354-5359.
    DOI » View record in Web of Science SM
  • Ho, Y., Kung, M., Yang, S., Wang, T. (2005). Multiplexed hybridization detection with multicolor colocalization of quantum dot nanoprobes. Nano Letters. 5(9). 1693-1697.
    DOI » View record in Web of Science SM
  • Wong, P., Chen, C., Wang, T., Ho, C. (2004). Electrokinetic bioprocessor for concentrating cells and molecules. Analytical Chemistry. 76(23). 6908-6914.
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  • Wong, P., Wang, T., Deval, J., Ho, C. (2004). Electrokinetics in micro devices for biotechnology applications. IEEE-ASME Transactions on Mechatronics. 9(2). 366-376.
    DOI » View record in Web of Science SM
Book Chapters
  • Wang, T.H., Liu, K., Yeh, H.C.A.P. (2010). Nanobiosensors. Microtechnology and Nanotechnology in Biomedical Applications. (pp.346-394).
Other Publications
  • Wang, T.H., Bailey, V.J., Zhang, Y., Liu, K. (2010). Quantum Dots DNA Nanosensors - Ultrasensitive Platform for Detecting Genomic Cancer Markers. BIOforum Europe. vol.1-2 pp.28-30.
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